The Relationship between Mitochondrial Genome Mutations in Monocytes and the Development of Obesity and Coronary Heart Disease
CONCLUSIONS: It was revealed that some variants of mitochondrial DNA (mtDNA) heteroplasmy are associated with CVD risk factors. The results demonstrate the potential for using these molecular genetic markers to develop personalized CVD and metabolic disorder treatments.PMID:38538346 | DOI:10.31083/j.fbs1601006 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - March 27, 2024 Category: Biomedical Science Authors: Taisiya V Tolstik Tatiana V Kirichenko Anastasia I Bogatyreva Yuliya V Markina Vladislav A Kalmykov Alexander M Markin Source Type: research
Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study
Cardiovasc Toxicol. 2024 Mar 27. doi: 10.1007/s12012-024-09846-5. Online ahead of print.ABSTRACTThe aim of this study was to comprehensively assess the causal relationship between the overall genetic effect of circulating ApoE levels and panvascular lesions using newer genome-wide association data and two-sample bidirectional Mendelian randomization (MR) analysis. Two-way MR using single-nucleotide polymorphisms of circulating ApoE as instrumental variables was performed using the highest-priority Genome-wide association study (GWAS) data, with factor-adjusted and data-corrected statistics, to estimate causal associations ...
Source: Cardiovascular Toxicology - March 27, 2024 Category: Cardiology Authors: Yi-Ming Shi Dian Ou Jia-Ting Li Le Bao Xiao-Dan Liu Wei Zhang Huang Ding Source Type: research
Value of cardiodynamicsgram in early diagnosis of patients with acute coronary syndrome
CONCLUSIONS: CDG has high value in early diagnosis of ACS patients and is expected to become an important means of early diagnosis of ACS in emergency.PMID:38538355 | DOI:10.3760/cma.j.cn121430-20231009-00851 (Source: Atherosclerosis)
Source: Atherosclerosis - March 27, 2024 Category: Cardiology Authors: Xiubing Gong Yanan Gu Xiangyue Jiang Qingli Dou Source Type: research
Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease
CONCLUSIONS: Due to limited evidence, we are uncertain if text messaging reduces medication adherence, fatal and non-fatal cardiovascular events, and combined cardiovascular events in people with cardiovascular diseases when compared to usual care. Furthermore, text messaging may result in little or no effect on low-density lipoprotein cholesterol, blood pressure, and heart rate compared to usual care. The included studies were of low methodological quality, and no studies assessed the effects of text messaging in low-income countries or beyond the 12-month follow-up. Long-term and high-quality randomised trials are needed...
Source: Cochrane Database of Systematic Reviews - March 27, 2024 Category: General Medicine Authors: Julie Redfern Qiang Tu Karice Hyun Matthew A Hollings Nashid Hafiz Clara Zwack Caroline Free Pablo Perel Clara K Chow Source Type: research
The Relationship between Mitochondrial Genome Mutations in Monocytes and the Development of Obesity and Coronary Heart Disease
CONCLUSIONS: It was revealed that some variants of mitochondrial DNA (mtDNA) heteroplasmy are associated with CVD risk factors. The results demonstrate the potential for using these molecular genetic markers to develop personalized CVD and metabolic disorder treatments.PMID:38538346 | DOI:10.31083/j.fbs1601006 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - March 27, 2024 Category: Biomedical Science Authors: Taisiya V Tolstik Tatiana V Kirichenko Anastasia I Bogatyreva Yuliya V Markina Vladislav A Kalmykov Alexander M Markin Source Type: research
Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study
Cardiovasc Toxicol. 2024 Mar 27. doi: 10.1007/s12012-024-09846-5. Online ahead of print.ABSTRACTThe aim of this study was to comprehensively assess the causal relationship between the overall genetic effect of circulating ApoE levels and panvascular lesions using newer genome-wide association data and two-sample bidirectional Mendelian randomization (MR) analysis. Two-way MR using single-nucleotide polymorphisms of circulating ApoE as instrumental variables was performed using the highest-priority Genome-wide association study (GWAS) data, with factor-adjusted and data-corrected statistics, to estimate causal associations ...
Source: Cardiovascular Toxicology - March 27, 2024 Category: Cardiology Authors: Yi-Ming Shi Dian Ou Jia-Ting Li Le Bao Xiao-Dan Liu Wei Zhang Huang Ding Source Type: research
Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease
CONCLUSIONS: Due to limited evidence, we are uncertain if text messaging reduces medication adherence, fatal and non-fatal cardiovascular events, and combined cardiovascular events in people with cardiovascular diseases when compared to usual care. Furthermore, text messaging may result in little or no effect on low-density lipoprotein cholesterol, blood pressure, and heart rate compared to usual care. The included studies were of low methodological quality, and no studies assessed the effects of text messaging in low-income countries or beyond the 12-month follow-up. Long-term and high-quality randomised trials are needed...
Source: Cochrane Database of Systematic Reviews - March 27, 2024 Category: General Medicine Authors: Julie Redfern Qiang Tu Karice Hyun Matthew A Hollings Nashid Hafiz Clara Zwack Caroline Free Pablo Perel Clara K Chow Source Type: research
The Relationship between Mitochondrial Genome Mutations in Monocytes and the Development of Obesity and Coronary Heart Disease
CONCLUSIONS: It was revealed that some variants of mitochondrial DNA (mtDNA) heteroplasmy are associated with CVD risk factors. The results demonstrate the potential for using these molecular genetic markers to develop personalized CVD and metabolic disorder treatments.PMID:38538346 | DOI:10.31083/j.fbs1601006 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - March 27, 2024 Category: Biomedical Science Authors: Taisiya V Tolstik Tatiana V Kirichenko Anastasia I Bogatyreva Yuliya V Markina Vladislav A Kalmykov Alexander M Markin Source Type: research
Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study
Cardiovasc Toxicol. 2024 Mar 27. doi: 10.1007/s12012-024-09846-5. Online ahead of print.ABSTRACTThe aim of this study was to comprehensively assess the causal relationship between the overall genetic effect of circulating ApoE levels and panvascular lesions using newer genome-wide association data and two-sample bidirectional Mendelian randomization (MR) analysis. Two-way MR using single-nucleotide polymorphisms of circulating ApoE as instrumental variables was performed using the highest-priority Genome-wide association study (GWAS) data, with factor-adjusted and data-corrected statistics, to estimate causal associations ...
Source: Cardiovascular Toxicology - March 27, 2024 Category: Cardiology Authors: Yi-Ming Shi Dian Ou Jia-Ting Li Le Bao Xiao-Dan Liu Wei Zhang Huang Ding Source Type: research
Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease
CONCLUSIONS: Due to limited evidence, we are uncertain if text messaging reduces medication adherence, fatal and non-fatal cardiovascular events, and combined cardiovascular events in people with cardiovascular diseases when compared to usual care. Furthermore, text messaging may result in little or no effect on low-density lipoprotein cholesterol, blood pressure, and heart rate compared to usual care. The included studies were of low methodological quality, and no studies assessed the effects of text messaging in low-income countries or beyond the 12-month follow-up. Long-term and high-quality randomised trials are needed...
Source: Cochrane Database of Systematic Reviews - March 27, 2024 Category: General Medicine Authors: Julie Redfern Qiang Tu Karice Hyun Matthew A Hollings Nashid Hafiz Clara Zwack Caroline Free Pablo Perel Clara K Chow Source Type: research
The Relationship between Mitochondrial Genome Mutations in Monocytes and the Development of Obesity and Coronary Heart Disease
CONCLUSIONS: It was revealed that some variants of mitochondrial DNA (mtDNA) heteroplasmy are associated with CVD risk factors. The results demonstrate the potential for using these molecular genetic markers to develop personalized CVD and metabolic disorder treatments.PMID:38538346 | DOI:10.31083/j.fbs1601006 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - March 27, 2024 Category: Biomedical Science Authors: Taisiya V Tolstik Tatiana V Kirichenko Anastasia I Bogatyreva Yuliya V Markina Vladislav A Kalmykov Alexander M Markin Source Type: research
Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease
CONCLUSIONS: Due to limited evidence, we are uncertain if text messaging reduces medication adherence, fatal and non-fatal cardiovascular events, and combined cardiovascular events in people with cardiovascular diseases when compared to usual care. Furthermore, text messaging may result in little or no effect on low-density lipoprotein cholesterol, blood pressure, and heart rate compared to usual care. The included studies were of low methodological quality, and no studies assessed the effects of text messaging in low-income countries or beyond the 12-month follow-up. Long-term and high-quality randomised trials are needed...
Source: Cochrane Database of Systematic Reviews - March 27, 2024 Category: General Medicine Authors: Julie Redfern Qiang Tu Karice Hyun Matthew A Hollings Nashid Hafiz Clara Zwack Caroline Free Pablo Perel Clara K Chow Source Type: research
The Relationship between Mitochondrial Genome Mutations in Monocytes and the Development of Obesity and Coronary Heart Disease
CONCLUSIONS: It was revealed that some variants of mitochondrial DNA (mtDNA) heteroplasmy are associated with CVD risk factors. The results demonstrate the potential for using these molecular genetic markers to develop personalized CVD and metabolic disorder treatments.PMID:38538346 | DOI:10.31083/j.fbs1601006 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - March 27, 2024 Category: Biomedical Science Authors: Taisiya V Tolstik Tatiana V Kirichenko Anastasia I Bogatyreva Yuliya V Markina Vladislav A Kalmykov Alexander M Markin Source Type: research
Mobile phone text messaging for medication adherence in secondary prevention of cardiovascular disease
CONCLUSIONS: Due to limited evidence, we are uncertain if text messaging reduces medication adherence, fatal and non-fatal cardiovascular events, and combined cardiovascular events in people with cardiovascular diseases when compared to usual care. Furthermore, text messaging may result in little or no effect on low-density lipoprotein cholesterol, blood pressure, and heart rate compared to usual care. The included studies were of low methodological quality, and no studies assessed the effects of text messaging in low-income countries or beyond the 12-month follow-up. Long-term and high-quality randomised trials are needed...
Source: Cochrane Database of Systematic Reviews - March 27, 2024 Category: General Medicine Authors: Julie Redfern Qiang Tu Karice Hyun Matthew A Hollings Nashid Hafiz Clara Zwack Caroline Free Pablo Perel Clara K Chow Source Type: research
