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Meta-analysis of the Relationship Between Zinc and Copper in Patients with Osteoarthritis
This study aims to explore the relationship between osteoarthritis and the trace elements zinc and copper and to provide a theoretical basis for research on the related mechanisms for the prevention, diagnosis, and treatment of osteoarthritis. We searched all the literature indexed in Web Of Science, Embase, and PubMed as of January 10, 2024, summarized the zinc and copper detection indexes in patients with osteoarthritis, obtained clinical data through literature screening, quality assessment, and data extraction, and analyzed the data using Revman 5.4. A total of 13 papers were included in this study, totaling 7983 study...
Source: Biological Trace Element Research - April 27, 2024 Category: Biology Authors: Haowei Zhou Yuchen Zhang Tian Tian Bingqian Wang Yalei Pan Source Type: research

Ultrasensitive NIR fluorometric assay for inorganic pyrophosphatase detection via Cu 2+ -PPi interaction using bimetallic Au-Ag nanoclusters
Anal Chim Acta. 2024 May 29;1305:342584. doi: 10.1016/j.aca.2024.342584. Epub 2024 Apr 10.ABSTRACTBACKGROUND: Inorganic pyrophosphatase (PPase) is key enzyme playing a key role in biochemical transformations such as biosynthesis of DNA and RNA, bone formation, metabolic pathways associated with lipid, carbohydrate and phosphorous. It has been reported that lung adenocarcinomas, colorectal cancer, and hyperthyroidism disorders can result from abnormal level of PPase. Therefore, it is of notable significance to develop simple and effective real time assay for PPase enzyme activity monitoring for screening of many metabolic p...
Source: Analytica Chimica Acta - April 27, 2024 Category: Chemistry Authors: Deepika Sharma Nishima Wangoo Rohit K Sharma Source Type: research

Decellularized periosteum and sodium alginate-based photoresponsive dressing with copper selenide nanoparticles for infected-wound healing in diabetic mice
Int J Biol Macromol. 2024 Apr 25:131895. doi: 10.1016/j.ijbiomac.2024.131895. Online ahead of print.ABSTRACTDiabetes-related skin ulcers are of significant clinical concern. Although conventional dressings have been developed, their outcomes have not been adequate, indicating the need to investigate functional dressings for the treatment of diabetic ulcers. Copper selenide nanoparticles (Cu2Se NPs) demonstrate outstanding photoresponsiveness, which is critical to the healing process. However, their limited solubility in water restricts their application. To synthesize the ODT-PMMA@Cu2Se NP-doped decellularized periosteum�...
Source: International Journal of Biological Macromolecules - April 27, 2024 Category: Biochemistry Authors: Zhiwen Su Yan Chen Haifeng Liang Zhongxun Liu Deguang Wu Jian Li Hao Su Yiran Yan Zhi Huang Bo Yu Source Type: research

Combined effect of grooves and nanoflower structured Co 3 O 4 coating on bamboo wood for highly efficient solar steam generation at indoor and outdoor conditions
Environ Sci Pollut Res Int. 2024 Apr 27. doi: 10.1007/s11356-024-33420-9. Online ahead of print.ABSTRACTCurrently, interfacial solar steam generation (ISSG) in desalinating water has become very popular for obtaining purified water from polluted water. However, finding an efficient evaporator with low cost is a challenging task for researchers. In this work, we introduce natural bamboo wood (BW) that acts as an interfacial evaporator for obtaining purified water. Four different wood evaporators namely, flat wood (BW-FW), two-cut grooved wood (BW-2G), four-cut grooved wood (BW-4G), and four-cut grooved with Co3O4-coated woo...
Source: Environmental Science and Pollution Research International - April 27, 2024 Category: Environmental Health Authors: Marimuthu Rengasamy Arulmurugan Gnanasekaran Nandhakumar Eswaramoorthy Indhumathy Basker Kamatchi Rajaram Source Type: research

Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition
This study not only provided a potent agent for the TNBC treatment, but also demonstrated the universality of the bioorthogonally catalyzed lethality (BCL) strategy through CuAAC reation.PMID:38677004 | DOI:10.1016/j.jinorgbio.2024.112574 (Source: Journal of Inorganic Biochemistry)
Source: Journal of Inorganic Biochemistry - April 27, 2024 Category: Biochemistry Authors: Guan-Dong Zhang Meng-Meng Wang Yan Su Hongbao Fang Xu-Ling Xue Hong-Ke Liu Zhi Su Source Type: research

Chip-based automated equipment for dual-mode point-of-care testing foodborne pathogens
Biosens Bioelectron. 2024 Apr 25;257:116338. doi: 10.1016/j.bios.2024.116338. Online ahead of print.ABSTRACTFoodborne pathogens have a substantial bearing on food safety and environmental health. The development of automated, portable and compact devices is essential for the on-site and rapid point-of-care testing (POCT) of bacteria. Here, this work developed a micro-automated microfluidic device for detecting bacteria, such as Escherichia coli (E. coli) O157:H7, using a seashell-like microfluidic chip (SMC) as an analysis and mixing platform. The automated device integrates a colorimetric/fluorescent system for the metabo...
Source: Biosensors and Bioelectronics - April 27, 2024 Category: Biotechnology Authors: Binfeng Yin Haoyu Zhu Shiyu Zeng A S M Muhtasim Fuad Sohan Xinhua Wan Jun Liu Pan Zhang Xiaodong Lin Source Type: research

Adsorption structures, vibrational Raman spectra and chemical binding properties of thioglycolic acid on Cu(111) surfaces: A DFT study
Chemphyschem. 2024 Apr 27:e202400330. doi: 10.1002/cphc.202400330. Online ahead of print.ABSTRACTCopper is widely used in everyday life and industrial production because of its good electrical and thermal conductivity. To overcome copper oxidation and maintain its good physical properties, small organic molecules adsorbed on the surface of copper make a passivated layer to further avoid copper corrosion. In this work, we have investigated thioglycolic acid (TGA, another name is mercaptoacetic acid) adsorbed on copper surfaces by using density functional theory (DFT) calculations and a periodical slab model. We first get fi...
Source: Chemphyschem - April 27, 2024 Category: Chemistry Authors: Lai-Ke Chen Yuan-Hui Xiao Jian-De Lin Zubia Sajid Jian-Zhang Zhou De-Yin Wu Zhong-Qun Tian Source Type: research

Zinc oxide nanoflakes supported copper oxide nanosheets as a bifunctional electrocatalyst for OER and HER in an alkaline medium
Environ Res. 2024 Apr 25:119030. doi: 10.1016/j.envres.2024.119030. Online ahead of print.ABSTRACTBifunctional electrocatalysts are the attractive research in the hydrogen evolution reaction (HER) and the oxygen evolution reaction (OER) in the overall water-splitting reactions. The design and development of the cost-effective OER/HER bifunctional electrocatalysts with superior catalytic activity are still remaining as the big challenges. Herein, we have developed the CuO-ZnO nanocomposite as a bifunctional OER/HER electrocatalyst via simple chemical precipitation method. The nanocomposite was investigated for its crystalli...
Source: Environmental Research - April 27, 2024 Category: Environmental Health Authors: M Praveen Kumar Natesan Kumaresan R V Mangalaraja Irina Zaporotskova A Arulraj G Murugadoss A Pugazhendhi Source Type: research

Oenothera biennis with strong copper toxicity resistance enriches trace copper in seeds under copper pollution soil
Ecotoxicol Environ Saf. 2024 Apr 25;277:116382. doi: 10.1016/j.ecoenv.2024.116382. Online ahead of print.ABSTRACTExcess copper (Cu) imparts negative effects on plant growth and productivity in soil. To develop the ability of O. biennis to govern pollution soil containing excessive Cu, we investigated seed germination, seedling growth, and seed yield. Furthermore, Cu content and the expression levels of Cu transport related genes in different tissues were measured under exogenous high concentration Cu. O. biennis seeds were sensitive to excess Cu, with an observed reduction in the germination rate, primary root length, fres...
Source: Ecotoxicology and Environmental Safety - April 27, 2024 Category: Environmental Health Authors: Jie Dong Shuchang Yang Zhiling Kou Yunting Chen Tao Yang Peng Gao Wuhua Zhang Jinzhu Zhang Daidi Che Aoxue Wang Source Type: research

Biochemical and molecular-level effects of co-exposure to chlorpyrifos and lambda-cyhalothrin on the earthworm (Eisenia fetida)
Ecotoxicol Environ Saf. 2024 Apr 26;277:116374. doi: 10.1016/j.ecoenv.2024.116374. Online ahead of print.ABSTRACTFarmland soil organisms frequently encounter pesticide mixtures presented in their living environment. However, the underlying toxic mechanisms employed by soil animals to cope with such combined pollution have yet to be explored. This investigation aimed to reveal the changes in cellular and mRNA levels under chlorpyrifos (CPF) and lambda-cyhalothrin (LCT) co-exposures in earthworms (Eisenia fetida). Results exhibited that the combination of CPF and LCT triggered an acute synergistic influence on the animals. M...
Source: Ecotoxicology and Environmental Safety - April 27, 2024 Category: Environmental Health Authors: Dou Wang Liping Chen Guiling Yang Zhenlan Xu Lu Lv Tao Tang Yanhua Wang Source Type: research