Elderly-onset severe parkinsonism in Wilson Disease: A case report
Background: Wilson ’s disease (WD) is an autosomal-recessive copper metabolism disease caused by ATP7B mutations. Here, we reported an unusual case of an elderly WD patient with progressive parkinsonism and a unique therapy regimen. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: K.-F. Li, J. Li, Y.-P. Liao, S.-H. Zhu, C. Jagadish K, H.-Z. Chen, W.-M. Yang Source Type: research
Elevated salivary copper levels in patients with Wilson's disease
This study assesses whether salivary copper is increased in Wilson’s disea se patients compared to healthy controls. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: P.A.A.M. Bonilha, V. Cavalcanti de Souza, I. Brand ão, F. Santos Costa, C.D.B. Amaral, B. Gioppo Betini, E. Reis Barbosa, H.A. Ghizoni Teive Source Type: research
Cuproptosis: unveiling a new frontier in cancer biology and therapeutics
Copper plays vital roles in numerous cellular processes and its imbalance can lead to oxidative stress and dysfunction. Recent research has unveiled a unique form of copper-induced cell death, termed cuproptos... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - May 1, 2024 Category: Molecular Biology Authors: Ying Feng, Zhibo Yang, Jianpeng Wang and Hai Zhao Tags: Review Source Type: research
Fabrication of a sustainable superhydrophobic surface of Ag-NPs@SA on copper alloy for corrosion resistance, photocatalysis, and simulated distribution of Ag atoms
Analyst, 2024, Advance Article DOI: 10.1039/D3AN02182C, PaperNoor Hassan, Zeeshan Ajmal, Sun Liang heng, Khaled Fahmi Fawy, Sajid Mahmood, Fazila Mushtaq, Munirah D. Albaqami, Saikh Mohammad, Raqiqa Tur Rasool, Ghulam Abbas Ashraf Artificial superhydrophobic surfaces that do not absorb water, in a similar way to the lotus leaf, show tremendous promise in numerous applications. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - April 30, 2024 Category: Chemistry Authors: Noor Hassan Source Type: research
Rapid and Green Fabrication of Nanozyme with Geminal CuN3O Configuration for Efficient Catecholase ‐Mimicking
An efficient catecholase-like nanozyme with geminal CuN3O configuration is fabricated, which shows potential applications in biocatalysis and analytical detection. AbstractFabrication of nanozyme with catecholase-like catalytic activity faces the great challenge of merging outstanding activity with low cost as well as simple, rapid, and low-energy-consumed production, restricting its industrial applications. Herein, an inexpensive yet robust nanozyme (i.e., DT-Cu) via simple one-step coordination between diaminotriazole (DT) and CuSO4 within 1 h in water at room temperature is constructed. The asymmetric dicopper site wi...
Source: Small - April 30, 2024 Category: Nanotechnology Authors: Meng Yuan,
Ke Han,
Hong Yang,
Li Mi,
Chaofeng Huang,
Xun Hu,
Fei He Tags: Research Article Source Type: research
Facile fabrication of nanocellulose-supported membrane composited with modified carbon nitride and HKUST-1 for efficient photocatalytic degradation of formaldehyde
In this study, we developed a novel composite membrane material capable of adsorbing and photo-catalyzing formaldehyde by immobilizing HKUST-1 (copper open framework composed of 1,3,5-benzenetricarboxylic acid) onto NFC (Nano-fibrillated cellulose) membranes and subsequently loading modified carbon nitride. The synthesized CNx@HN composite membrane (consisting of NFC membrane with anchored HKUST-1 and modified g-C3Nx nanosheets) was thoroughly characterized, and its photocatalytic degradation performance towards low concentrations of formaldehyde (3.0 mg/m3) was investigated. The results demonstrated that HKUST-1's porous ...
Source: International Journal of Biological Macromolecules - April 30, 2024 Category: Biochemistry Authors: Zicheng Chen Xuefeng Zhang Kai Xu Xiangyang He Junkai Li Lanhe Zhang Guanhua Wang Source Type: research
Encapsulation of copper phenanthroline within horse spleen apoferritin: characterisation, cytotoxic activity and ability to retain temozolomide
RSC Adv. 2024 Apr 29;14(20):14008-14016. doi: 10.1039/d3ra07430g. eCollection 2024 Apr 25.ABSTRACTProtein capsules are promising drug delivery vehicles for cancer research therapies. Apoferritin (AFt) is a self-assembling 12 nm diameter hollow nanocage with many desirable features for drug delivery, however, control of drug retention inside the protein cage remains challenging. Here we report the encapsulation of copper(ii)-1,10-phenanthroline (Cu(phen)) within the horse spleen AFt (HSAFt) nanocage, by diffusion of the metal through the pores between the protein subunits. Transmission electron microscopy revealed the forma...
Source: Cancer Control - April 30, 2024 Category: Cancer & Oncology Authors: Maria Letizia Cassioli Michael Fay Lyudmila Turyanska Tracey D Bradshaw Neil R Thomas Anca Pordea Source Type: research
Deciphering Cuproptosis-related Signatures in Pediatric Allergic Asthma using Integrated scRNA-seq and Bulk RNA-seq Analysis
Conclusion This work provided a machine learning model containing five important variables, which may have good diagnostic efficiency for pediatric AA.PMID:38687912 | DOI:10.1080/02770903.2024.2349596 (Source: Journal of Asthma)
Source: Journal of Asthma - April 30, 2024 Category: Respiratory Medicine Authors: Jingping Liu Yujia Sun Chunxin Tian Dong Qin Lanying Gao Source Type: research
Copper/Polyaniline Interfaces Confined CO2 Electroreduction for Selective Hydrocarbon Production
ChemSusChem. 2024 Apr 30:e202400209. doi: 10.1002/cssc.202400209. Online ahead of print.ABSTRACTPolyaniline (PANI) provides an attractive organic platform for CO2 electrochemical reduction due to the ability to adsorb CO2 molecules and in providing means to interact with metal nanostructures. In this work, a novel PANI supported copper catalyst has been developed by coupling the interfacial polymerization of PANI and Cu nanoparticles. The hybrid catalyst demonstrates excellent activity towards production of hydrocarbon products including CH4 and C2H4, compared with the use of bare Cu nanoparticles. A faradaic efficiency of...
Source: ChemSusChem - April 30, 2024 Category: Chemistry Authors: Yeqing Xu Yong Zhao Alena Kochubei Chong Yong Lee Pawel Wagner Zhiqi Chen Yijiao Jiang Wei Yan Gordon Wallace Caiyun Wang Source Type: research
Novel isatin-triazole based thiosemicarbazones as potential anticancer agents: synthesis, DFT and molecular docking studies
In this study, two distinct types of isatin-triazole hybrids 3a and 3b were accessed via copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC), together with their mono and bis-thiosemicarbazone derivatives 4a-h and 5a-h. In addition to the characterization by physical, spectral and analytical data, a DFT study was carried out to obtain the optimized geometries of all thiosemicarbazones. The global reactivity values showed that among the synthesized derivatives, 4c, 4g and 5c having nitro substituents are the most soft compounds, with compound 5c having the highest electronegativity and electrophilicity index values...
Source: Adv Data - April 30, 2024 Category: Epidemiology Authors: Alia Mushtaq Rabbia Asif Waqar Ahmed Humayun Muhammad Moazzam Naseer Source Type: research
Control over Anion Coordination on Pd(II), Cu(I), and Ag(I) with Regioisomeric Phosphine-Carboxylate Ligands
Chemistry. 2024 Apr 30:e202401215. doi: 10.1002/chem.202401215. Online ahead of print.ABSTRACTThe coordination of anionic donors is involved at various stages of catalytic cycles in transition-metal catalysis, but control over the spatial positioning of anions around a metal center is a challenge in coordination chemistry. Here we show that regioisomeric phosphine-carboxylate ligands provide spatial anion control on palladium(II) centers by favoring either κ2, cis-κ1, or trans-κ1 coordination of the carboxylate donor. Additionally, the palladium(II) carboxylates, which contain a methyl donor, upon protonation, deliver m...
Source: Chemistry - April 30, 2024 Category: Chemistry Authors: Elisa Gonz ález-Fernández Nittert Marinus Jyoti Dhankhar Anthony Linden Ilija Coric Source Type: research
Facile fabrication of nanocellulose-supported membrane composited with modified carbon nitride and HKUST-1 for efficient photocatalytic degradation of formaldehyde
In this study, we developed a novel composite membrane material capable of adsorbing and photo-catalyzing formaldehyde by immobilizing HKUST-1 (copper open framework composed of 1,3,5-benzenetricarboxylic acid) onto NFC (Nano-fibrillated cellulose) membranes and subsequently loading modified carbon nitride. The synthesized CNx@HN composite membrane (consisting of NFC membrane with anchored HKUST-1 and modified g-C3Nx nanosheets) was thoroughly characterized, and its photocatalytic degradation performance towards low concentrations of formaldehyde (3.0 mg/m3) was investigated. The results demonstrated that HKUST-1's porous ...
Source: International Journal of Biological Macromolecules - April 30, 2024 Category: Biochemistry Authors: Zicheng Chen Xuefeng Zhang Kai Xu Xiangyang He Junkai Li Lanhe Zhang Guanhua Wang Source Type: research
Carbonized cellulose microspheres loaded with Pd NPs as catalyst in p-nitrophenol reduction and Suzuki-Miyaura coupling reaction
Int J Biol Macromol. 2024 Apr 28:131904. doi: 10.1016/j.ijbiomac.2024.131904. Online ahead of print.ABSTRACTCatalytic reduction of p-nitrophenol is usually carried out using transition metal nanoparticles such as gold, palladium, silver and copper, especially palladium nanoparticles, which are characterized by fast reaction rate, high turnover frequency, good selectivity and high yield. However, the aggregation and precipitation of the metals lead to the decomposition of the catalyst, which results in a significant reduction of the catalytic activity. Therefore, the preparation of homogeneous stabilized palladium nanoparti...
Source: International Journal of Biological Macromolecules - April 30, 2024 Category: Biochemistry Authors: Jiayin Gao Yaoyao Wang Yuqing Yu Mengxiang Zhu Wen Kong Genyan Liu Xiaogang Luo Source Type: research
Synthesis, characterization, and investigation of antibacterial activity of Novel CMC/CuO NPs/CQDs bionanocomposite coating
Int J Biol Macromol. 2024 Apr 28:131922. doi: 10.1016/j.ijbiomac.2024.131922. Online ahead of print.ABSTRACTIn recent decades, healthcare-associated infections (HAIs) have become a common problem in healthcare facilities such as hospitals. As a result, researchers are currently developing nanocomposite coatings that are strengthened with antibacterial nanoparticles. In this research, a novel antibacterial bionanocomposite coating based on carboxymethyl cellulose polymer/copper oxide nanoparticles/carbon quantum dots was coated on medical grade 316 stainless steel by sol-gel dip-coating method. The effect of the concentrati...
Source: International Journal of Biological Macromolecules - April 30, 2024 Category: Biochemistry Authors: Hamidreza Amoon Ayoub Moghadam Maryam Chalabi Hajkarim Source Type: research
The Oscillatory Behaviour of Cu-ZSM-5 Catalysts for N2O Decomposition: Investigation of Cu species by complementary techniques
Chemphyschem. 2024 Apr 30:e202400339. doi: 10.1002/cphc.202400339. Online ahead of print.ABSTRACTCopper-exchanged ZSM-5 (Cu-ZSM-5) is a promising catalyst thanks to the Cu redox pair. A particular feature of this material consists in the presence of spontaneous isothermal oscillations which take place during N2O decomposition reaction, depending on the operating conditions. In the present work, a set of five Cu-ZSM-5 catalysts are synthesised by three procedures and three different copper precursor concentrations: i) wet impregnation, ii) single ion exchange, and iii) double ion exchange. Catalytic tests reveal that the io...
Source: Chemphyschem - April 30, 2024 Category: Chemistry Authors: Andrea Rizzetto Enrico Sartoretti Khrystyna Khoma Marco Armandi Marco Piumetti Samir Bensaid Raffaele Pirone Source Type: research
