High-energy X-ray diffraction experiment employing a compact synchrotron X-ray source based on inverse Compton scattering
This study demonstrates high-energy XRD at an ICS with strongly absorbing mineralogical samples embedded in soft tissue. A quantitative comparison of the measured XRD patterns with calculations of their expected shapes validates the performance of ICSs for XRD. This analysis was performed for two types of kidney stones of different materials. Since these stones are not isolated in a human body, the influence of the surrounding soft tissue on the XRD pattern is investigated and a correction for this soft tissue contribution is introduced.PMID:38631968 | DOI:10.1016/j.zemedi.2024.03.003 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - April 17, 2024 Category: Radiology Authors: Johannes Melcher Martin Dierolf Benedikt G ünther Klaus Achterhold Daniela Pfeiffer Franz Pfeiffer Source Type: research
High-energy X-ray diffraction experiment employing a compact synchrotron X-ray source based on inverse Compton scattering
This study demonstrates high-energy XRD at an ICS with strongly absorbing mineralogical samples embedded in soft tissue. A quantitative comparison of the measured XRD patterns with calculations of their expected shapes validates the performance of ICSs for XRD. This analysis was performed for two types of kidney stones of different materials. Since these stones are not isolated in a human body, the influence of the surrounding soft tissue on the XRD pattern is investigated and a correction for this soft tissue contribution is introduced.PMID:38631968 | DOI:10.1016/j.zemedi.2024.03.003 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - April 17, 2024 Category: Radiology Authors: Johannes Melcher Martin Dierolf Benedikt G ünther Klaus Achterhold Daniela Pfeiffer Franz Pfeiffer Source Type: research
High-energy X-ray diffraction experiment employing a compact synchrotron X-ray source based on inverse Compton scattering
This study demonstrates high-energy XRD at an ICS with strongly absorbing mineralogical samples embedded in soft tissue. A quantitative comparison of the measured XRD patterns with calculations of their expected shapes validates the performance of ICSs for XRD. This analysis was performed for two types of kidney stones of different materials. Since these stones are not isolated in a human body, the influence of the surrounding soft tissue on the XRD pattern is investigated and a correction for this soft tissue contribution is introduced.PMID:38631968 | DOI:10.1016/j.zemedi.2024.03.003 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - April 17, 2024 Category: Radiology Authors: Johannes Melcher Martin Dierolf Benedikt G ünther Klaus Achterhold Daniela Pfeiffer Franz Pfeiffer Source Type: research
High-energy X-ray diffraction experiment employing a compact synchrotron X-ray source based on inverse Compton scattering
This study demonstrates high-energy XRD at an ICS with strongly absorbing mineralogical samples embedded in soft tissue. A quantitative comparison of the measured XRD patterns with calculations of their expected shapes validates the performance of ICSs for XRD. This analysis was performed for two types of kidney stones of different materials. Since these stones are not isolated in a human body, the influence of the surrounding soft tissue on the XRD pattern is investigated and a correction for this soft tissue contribution is introduced.PMID:38631968 | DOI:10.1016/j.zemedi.2024.03.003 (Source: Zeitschrift fur Medizinische Physik)
Source: Zeitschrift fur Medizinische Physik - April 17, 2024 Category: Radiology Authors: Johannes Melcher Martin Dierolf Benedikt G ünther Klaus Achterhold Daniela Pfeiffer Franz Pfeiffer Source Type: research
Comparison of trace elements in peripheral blood and bone marrow of newly diagnosed multiple myeloma patients
In this study, we aimed to evaluate alterations in trace elements in the blood and bone marrow serum of patients with newly diagnosed multiple myeloma (NMM). The levels of zinc (Zn), copper (Cu), iron (Fe), manganese (Mn), magnesium (Mg), selenium (Se), arsenic (As), boron (B), nickel (Ni), silicon (Si) and chromium (Cr) were analyzed in the venous blood samples of the patient group comprising 70 patients with NMM (41 males and 29 females) and compared to those in the control group comprising 30 individuals (18 males and 12 females). In addition, trace element levels were analyzed in bone marrow samples from the patient gr...
Source: Clinical and Experimental Medicine - April 17, 2024 Category: Research Source Type: research
Cuproptosis: Advances in Stimulus-Responsive Nanomaterials for Cancer Therapy
Adv Healthc Mater. 2024 Apr 15:e2400652. doi: 10.1002/adhm.202400652. Online ahead of print.ABSTRACTCuproptosis, a recently identified non-apoptotic programmed cell death modality, attracts considerable attention in the realm of cancer therapeutics owing to its unique cellular demise mechanisms. Since its initial report in 2022, strategies inducing or amplifying cuproptosis for cancer treatment emerge. The engineering of nano-systems to elicit cuproptosis effectively circumvents constraints associated with conventional small-molecule pharmaceutical interventions, presenting novel prospects for oncological therapy. Stimulus...
Source: Cancer Control - April 16, 2024 Category: Cancer & Oncology Authors: Jiacheng Lu Yuqing Miao Yuhao Li Source Type: research
A comparative in vitro and in vivo analysis of the impact of copper substitution on the cytocompatibility, osteogenic, and angiogenic properties of a borosilicate bioactive glass
J Biomed Mater Res A. 2024 Apr 15. doi: 10.1002/jbm.a.37721. Online ahead of print.ABSTRACTThe 0106-B1-bioactive glass (BG) composition (in wt %: 37.5 SiO2, 22.6 CaO, 5.9 Na2O, 4.0 P2O5, 12.0 K2O, 5.5 MgO, and 12.5 B2O3) has demonstrated favorable processing properties and promising bone regeneration potential. The present study aimed to evaluate the biological effects of the incorporation of highly pro-angiogenic copper (Cu) in 0106-B1-BG in vitro using human bone marrow-derived mesenchymal stromal cells (BMSCs) as well as its in vivo potential for bone regeneration. CuO was added to 0106-B1-BG in exchange for CaO, result...
Source: Biomed Res - April 16, 2024 Category: Research Authors: Linn Anna Fiehn Elke Kunisch Merve Saur Marcela Arango-Ospina Christian Merle S ébastien Hagmann Adrian Stiller Leena Hupa Hana Ka ňková Dagmar Galuskov á Tobias Renkawitz Aldo R Boccaccini Fabian Westhauser Source Type: research
Molecular characterization and evaluation of novel management options for Burkholderia glumae BG1, the causative agent of panicle blight of rice (Oryza sativa L.)
CONCLUSIONS: Overall, our study provides valuable insights into the potential and practical application of nano copper for the mitigation of bacterial panicle blight, offering promising prospects for commercial utilization in disease management.PMID:38625424 | DOI:10.1007/s11033-024-09498-2 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 16, 2024 Category: Molecular Biology Authors: Bhaskaran Sreenayana Kalyan Kumar Mondal Nivetha Mathiyalagan Kalaivanan Nagaranai Shanmugam Sanjeev Kumar Mrutyunjaya Shrinivas Reddy Chander Mani Source Type: research
Anaerobic treatment of groundwater co-contaminated by toluene and copper in a single chamber bioelectrochemical system
Bioelectrochemistry. 2024 Apr 13;158:108711. doi: 10.1016/j.bioelechem.2024.108711. Online ahead of print.ABSTRACTAddressing the simultaneous removal of multiple coexisting groundwater contaminants poses a significant challenge, primarily because of their different physicochemical properties. Indeed, different chemical compounds may necessitate establishing distinct, and sometimes conflicting, (bio)degradation and/or removal pathways. In this work, we investigated the concomitant anaerobic treatment of toluene and copper in a single-chamber bioelectrochemical cell with a potential difference of 1 V applied between the anod...
Source: Bioelectrochemistry - April 16, 2024 Category: Biochemistry Authors: Marco Resitano Matteo Tucci Alessio Mezzi Saulius Kaciulis Bruna Matturro Emilio D'Ugo Lucia Bertuccini Stefano Fazi Simona Rossetti Federico Aulenta Carolina Cruz Viggi Source Type: research
A novel organic-inorganic matrix nanofiltration membrane for remediating copper with enhanced thermal stability and mechanical strength
Environ Sci Pollut Res Int. 2024 Apr 16. doi: 10.1007/s11356-024-33321-x. Online ahead of print.ABSTRACTMembrane separation technology in the last 40 years has experienced impressive growth, displacing conventional separation processes due to inherent advantages such as less capital investment, and energy efficiency and the devices were simple, compact, and modular. In the current work, we aimed to synthesize a thin-sheet nanofiltration membrane using chitosan (CS), poly(vinyl) alcohol (PVA), and montmorillonite nanoclay (MMT) for copper removal from aqueous solution. Thermogravimetric analysis and differential scanning ca...
Source: Environmental Science and Pollution Research International - April 16, 2024 Category: Environmental Health Authors: Sangeetha Kirubanandam Latha Srinivasan Matar Alshalwi Ashok Kumar Rajamanickam Sudha Parappurath Narayanan Source Type: research
A comparative in vitro and in vivo analysis of the impact of copper substitution on the cytocompatibility, osteogenic, and angiogenic properties of a borosilicate bioactive glass
J Biomed Mater Res A. 2024 Apr 15. doi: 10.1002/jbm.a.37721. Online ahead of print.ABSTRACTThe 0106-B1-bioactive glass (BG) composition (in wt %: 37.5 SiO2, 22.6 CaO, 5.9 Na2O, 4.0 P2O5, 12.0 K2O, 5.5 MgO, and 12.5 B2O3) has demonstrated favorable processing properties and promising bone regeneration potential. The present study aimed to evaluate the biological effects of the incorporation of highly pro-angiogenic copper (Cu) in 0106-B1-BG in vitro using human bone marrow-derived mesenchymal stromal cells (BMSCs) as well as its in vivo potential for bone regeneration. CuO was added to 0106-B1-BG in exchange for CaO, result...
Source: Biomed Res - April 16, 2024 Category: Research Authors: Linn Anna Fiehn Elke Kunisch Merve Saur Marcela Arango-Ospina Christian Merle S ébastien Hagmann Adrian Stiller Leena Hupa Hana Ka ňková Dagmar Galuskov á Tobias Renkawitz Aldo R Boccaccini Fabian Westhauser Source Type: research
Anaerobic treatment of groundwater co-contaminated by toluene and copper in a single chamber bioelectrochemical system
Bioelectrochemistry. 2024 Apr 13;158:108711. doi: 10.1016/j.bioelechem.2024.108711. Online ahead of print.ABSTRACTAddressing the simultaneous removal of multiple coexisting groundwater contaminants poses a significant challenge, primarily because of their different physicochemical properties. Indeed, different chemical compounds may necessitate establishing distinct, and sometimes conflicting, (bio)degradation and/or removal pathways. In this work, we investigated the concomitant anaerobic treatment of toluene and copper in a single-chamber bioelectrochemical cell with a potential difference of 1 V applied between the anod...
Source: Bioelectrochemistry - April 16, 2024 Category: Biochemistry Authors: Marco Resitano Matteo Tucci Alessio Mezzi Saulius Kaciulis Bruna Matturro Emilio D'Ugo Lucia Bertuccini Stefano Fazi Simona Rossetti Federico Aulenta Carolina Cruz Viggi Source Type: research
Anaerobic treatment of groundwater co-contaminated by toluene and copper in a single chamber bioelectrochemical system
Bioelectrochemistry. 2024 Apr 13;158:108711. doi: 10.1016/j.bioelechem.2024.108711. Online ahead of print.ABSTRACTAddressing the simultaneous removal of multiple coexisting groundwater contaminants poses a significant challenge, primarily because of their different physicochemical properties. Indeed, different chemical compounds may necessitate establishing distinct, and sometimes conflicting, (bio)degradation and/or removal pathways. In this work, we investigated the concomitant anaerobic treatment of toluene and copper in a single-chamber bioelectrochemical cell with a potential difference of 1 V applied between the anod...
Source: Bioelectrochemistry - April 16, 2024 Category: Biochemistry Authors: Marco Resitano Matteo Tucci Alessio Mezzi Saulius Kaciulis Bruna Matturro Emilio D'Ugo Lucia Bertuccini Stefano Fazi Simona Rossetti Federico Aulenta Carolina Cruz Viggi Source Type: research
Molecules, Vol. 29, Pages 1800: Dendritic Pyridine & ndash;Imine Copper Complexes as Metallo-Drugs
Molecules, Vol. 29, Pages 1800: Dendritic Pyridine–Imine Copper Complexes as Metallo-Drugs
Molecules doi: 10.3390/molecules29081800
Authors:
Régis Laurent
Valérie Maraval
Vania Bernardes-Génisson
Anne-Marie Caminade
Since the discovery of cisplatin in the 1960s, the search for metallo-drugs that are more efficient than platinum complexes with negligible side effects has attracted much interest. Among the other metals that have been examined for potential applications as anticancer agents is copper. The interest in copper was recently boosted by the discovery of cuproptosis, a recently evidenced f...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: R égis Laurent Val érie Maraval Vania Bernardes-G énisson Anne-Marie Caminade Tags: Review Source Type: research
