Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: Endocrine Reviews - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: Endocrine Reviews - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Attitudes and beliefs regarding Pain Medicine: results of a national palliative physician survey
CONCLUSION: This study shows that Palliative Care physicians have highly positive attitudes toward Pain Medicine specialists, but referrals remain low. Facilitating professional collaboration via joint educational/clinical sessions is one possible solution to drive ongoing interprofessional care in patients with complex pain.PMID:38677489 | DOI:10.1016/j.jpainsymman.2024.04.015 (Source: Pain Physician)
Source: Pain Physician - April 27, 2024 Category: Anesthesiology Authors: Daniel K Partain Wil L Santivasi Mihir M Kamdar Susan M Moeschler Jon C Tilburt Karen M Fischer Jacob J Strand Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: Endocrine Reviews - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Incremental Learning for Heterogeneous Structure Segmentation in Brain Tumor MRI
Med Image Comput Comput Assist Interv. 2023 Oct;14221:46-56. doi: 10.1007/978-3-031-43895-0_5. Epub 2023 Oct 1.ABSTRACTDeep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually evolving environment, requiring appropriate model updates. In an incremental learning setting, we would expect that well-trained static models are updated, following continually evolving target domain data-e.g., additional lesions or structures of interest-collected from diffe...
Source: MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention - April 26, 2024 Category: Radiology Authors: Xiaofeng Liu Helen A Shih Fangxu Xing Emiliano Santarnecchi Georges El Fakhri Jonghye Woo Source Type: research
Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research
The Canadian Breast Cancer Symposium 2023 Meeting Report
Curr Oncol. 2024 Mar 29;31(4):1774-1802. doi: 10.3390/curroncol31040135.ABSTRACTOn 15-16 June 2023, healthcare professionals and breast cancer patients and advocates from across Canada met in Toronto, Ontario, for the 2023 Canadian Breast Cancer Symposium (CBSC.). The CBSC. is a national, multidisciplinary event that occurs every 2 years with the goal of developing a personalized approach to the management of breast cancer in Canada. Experts provided state-of-the-art information to help optimally manage breast cancer patients, including etiology, prevention, diagnosis, experimental biology, and therapy of breast cancer and...
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tulin Cil Jean-Fran çois Boileau Stephen Chia M J DeCoteau Katarzyna J Jerzak Anne Koch Nancy Nixon May Lynn Quan Amanda Roberts Christine Brezden-Masley Source Type: research
Incremental Learning for Heterogeneous Structure Segmentation in Brain Tumor MRI
Med Image Comput Comput Assist Interv. 2023 Oct;14221:46-56. doi: 10.1007/978-3-031-43895-0_5. Epub 2023 Oct 1.ABSTRACTDeep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually evolving environment, requiring appropriate model updates. In an incremental learning setting, we would expect that well-trained static models are updated, following continually evolving target domain data-e.g., additional lesions or structures of interest-collected from diffe...
Source: MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention - April 26, 2024 Category: Radiology Authors: Xiaofeng Liu Helen A Shih Fangxu Xing Emiliano Santarnecchi Georges El Fakhri Jonghye Woo Source Type: research
Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research
The Canadian Breast Cancer Symposium 2023 Meeting Report
Curr Oncol. 2024 Mar 29;31(4):1774-1802. doi: 10.3390/curroncol31040135.ABSTRACTOn 15-16 June 2023, healthcare professionals and breast cancer patients and advocates from across Canada met in Toronto, Ontario, for the 2023 Canadian Breast Cancer Symposium (CBSC.). The CBSC. is a national, multidisciplinary event that occurs every 2 years with the goal of developing a personalized approach to the management of breast cancer in Canada. Experts provided state-of-the-art information to help optimally manage breast cancer patients, including etiology, prevention, diagnosis, experimental biology, and therapy of breast cancer and...
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Tulin Cil Jean-Fran çois Boileau Stephen Chia M J DeCoteau Katarzyna J Jerzak Anne Koch Nancy Nixon May Lynn Quan Amanda Roberts Christine Brezden-Masley Source Type: research
Incremental Learning for Heterogeneous Structure Segmentation in Brain Tumor MRI
Med Image Comput Comput Assist Interv. 2023 Oct;14221:46-56. doi: 10.1007/978-3-031-43895-0_5. Epub 2023 Oct 1.ABSTRACTDeep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually evolving environment, requiring appropriate model updates. In an incremental learning setting, we would expect that well-trained static models are updated, following continually evolving target domain data-e.g., additional lesions or structures of interest-collected from diffe...
Source: MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention - April 26, 2024 Category: Radiology Authors: Xiaofeng Liu Helen A Shih Fangxu Xing Emiliano Santarnecchi Georges El Fakhri Jonghye Woo Source Type: research
CellVis2: a conference on visualizing the molecular cell
Trends Biochem Sci. 2024 Apr 25:S0968-0004(24)00079-3. doi: 10.1016/j.tibs.2024.03.013. Online ahead of print.ABSTRACTIn January 2024, a targeted conference, 'CellVis2', was held at Scripps Research in La Jolla, USA, the second in a series designed to explore the promise, practices, roadblocks, and prospects of creating, visualizing, sharing, and communicating physical representations of entire biological cells at scales down to the atom.PMID:38670884 | DOI:10.1016/j.tibs.2024.03.013 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - April 26, 2024 Category: Biochemistry Authors: Ludovic Autin David S Goodsell Ivan Viola Arthur Olson Source Type: research
