Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: Respiratory Care)
Source: Respiratory Care - April 15, 2024 Category: Respiratory Medicine Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research

Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2024 Category: Respiratory Medicine Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research

Pediatric anesthesiology in Brazil, Chile, and Mexico
CONCLUSIONS: Brazil an upper middle-income country, population 203 million, has a public system insufficiently resourced and a private system, resulting in inequitable safety and accessibility. Surgical complications constitute the third leading cause of mortality. Anesthesiology residency is 3 years, with required rotations in pediatric anesthesia; five hospitals offer pediatric anesthesia fellowships. Anesthesiology is a physician-only practice. A Pediatric Anesthesia Committee within the Brazilian Society of Anesthesiology offers education through seasonal courses and workshops including pediatric advanced life support....
Source: Paediatric Anaesthesia - April 15, 2024 Category: Anesthesiology Authors: Vin ícius Caldeira Quintão Mario Concha Lina Andrea Sarmiento Arg üello Silvana Cavallieri Luis I Cortinez Gabriel Soares de Sousa Marcella Marino Malavazzi Clemente Ricardo Vieira Carlos Juan Manuel Rodr íguez Karla Guti érrez Denis H Jablonka Anner Source Type: research

Pelphix: Surgical Phase Recognition from X-ray Images in Percutaneous Pelvic Fixation
Med Image Comput Comput Assist Interv. 2023 Oct;14228:133-143. doi: 10.1007/978-3-031-43996-4_13. Epub 2023 Oct 1.ABSTRACTSurgical phase recognition (SPR) is a crucial element in the digital transformation of the modern operating theater. While SPR based on video sources is well-established, incorporation of interventional X-ray sequences has not yet been explored. This paper presents Pelphix, a first approach to SPR for X-ray-guided percutaneous pelvic fracture fixation, which models the procedure at four levels of granularity - corridor, activity, view, and frame value - simulating the pelvic fracture fixation workflow a...
Source: MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention - April 15, 2024 Category: Radiology Authors: Benjamin D Killeen Han Zhang Jan Mangulabnan Mehran Armand Russell H Taylor Greg Osgood Mathias Unberath Source Type: research

Chemists Invent Drugs and Drugs Save Lives
ChemMedChem. 2024 Apr 14:e202400074. doi: 10.1002/cmdc.202400074. Online ahead of print.ABSTRACTDrug molecules are the centrepiece of modern medical therapies, providing relief from pain, combatting infections and providing a myriad of other therapeutic effects. The quest for new and improved drug molecules drives medical research, and the introduction of a new drug frequently becomes a newsworthy event capturing the attention of the press and general public. And yet, misconceptions abound. Often, the general public thinks that drug molecules are designed, created, and invented by physicians rather than chemists - a misund...
Source: ChemMedChem - April 15, 2024 Category: Chemistry Authors: Donald F Weaver Source Type: research

Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: Respiratory Care)
Source: Respiratory Care - April 15, 2024 Category: Respiratory Medicine Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research

Household Air Pollution Interventions to Improve Health in Low- and Middle-Income Countries: An Official American Thoracic Society Research Statement
Conclusions: HAP is associated with adverse health effects in observational studies. However, it remains unclear which household energy interventions reduce exposure, improve health, can be scaled, and are sustainable. Researchers should engage with policy makers and practitioners working to scale cleaner energy solutions to understand and address their information needs.PMID:38619436 | DOI:10.1164/rccm.202402-0398ST (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 15, 2024 Category: Respiratory Medicine Authors: Peggy S Lai Nicholas L Lam Bill Gallery Alison G Lee Heather Adair-Rohani Donee Alexander Kalpana Balakrishnan Iwona Bisaga Zoe A Chafe Thomas Clasen Anait é Díaz-Artiga Andrew Grieshop Kat Harrison Stella M Hartinger Darby Jack Seyram Kaali Melissa Lyd Source Type: research

The N-LVA Study: effectiveness and cost-effectiveness of lymphaticovenous anastomosis (LVA) for patients with cancer who suffer from chronic peripheral lymphoedema - study protocol of a multicentre, randomised sham-controlled trial
The objective of this study is to evaluate whether LVA is effective and cost-effective compared with sham surgery in improving the HRQoL. Methods and analysis A multicentre, double-blind, randomised sham-controlled trial conducted in three university hospitals in the Netherlands. The study population comprises 110 patients over the age of 18 years with unilateral, peripheral cancer-related lymphoedema, including 70 patients with upper limb lymphoedema and 40 patients with lower limb lymphoedema. A total of 55 patients will undergo the LVA operation, while the remaining 55 will undergo sham surgery. The follow-up will be a...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Kleeven, A., Jonis, Y. M. J., Tielemans, H., van Kuijk, S., Kimman, M., van der Hulst, R., Vasilic, D., Hummelink, S., Qiu, S. S. Tags: Open access, Surgery Source Type: research

Artificial intelligence-based prediction of diabetic retinopathy evolution (EviRed): protocol for a prospective cohort
Introduction An important obstacle in the fight against diabetic retinopathy (DR) is the use of a classification system based on old imaging techniques and insufficient data to accurately predict its evolution. New imaging techniques generate new valuable data, but we lack an adapted classification based on these data. The main objective of the Evaluation Intelligente de la Rétinopathie Diabétique, Intelligent evaluation of DR (EviRed) project is to develop and validate a system assisting the ophthalmologist in decision-making during DR follow-up by improving the prediction of its evolution. Methods and anal...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Tadayoni, R., Massin, P., Bonnin, S., Magazzeni, S., Lay, B., Le Guilcher, A., Vicaut, E., Couturier, A., Quellec, G., Investigators, E. Tags: Open access, Ophthalmology Source Type: research

Effects of a therapeutic lifestyle modification intervention on cardiometabolic health, sexual functioning and health-related quality of life in perimenopausal Chinese women: protocol for a randomised controlled trial
Introduction Perimenopause is a critical transitional period in reproductive ageing. A set of physiological and psychological changes can affect perimenopausal women’s quality of life and further threaten their older adult health conditions. In China, less than one-third of midlife women with menopausal symptoms have actively sought professional healthcare. Regarding the public health significance of comprehensive menopause management, the current study aims to investigate the effects of a therapeutic lifestyle modification (TLM) intervention on cardiometabolic health, sexual functioning and health-related quality of...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Wang, Y., Miao, X., Viwattanakulvanid, P. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research

Predictive performance of machine learning compared to statistical methods in time-to-event analysis of cardiovascular disease: a systematic review protocol
Background Globally, cardiovascular disease (CVD) remains the leading cause of death, warranting effective management and prevention measures. Risk prediction tools are indispensable for directing primary and secondary prevention strategies for CVD and are critical for estimating CVD risk. Machine learning (ML) methodologies have experienced significant advancements across numerous practical domains in recent years. Several ML and statistical models predicting CVD time-to-event outcomes have been developed. However, it is not known as to which of the two model types—ML and statistical models—have higher discrim...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Suliman, A., Masud, M., Serhani, M. A., Abdullahi, A. S., Oulhaj, A. Tags: Open access, Cardiovascular medicine Source Type: research

Labour Care Guide implementation as a decision-making tool for monitoring labour among healthcare providers in Uganda: protocol for a mixed-methods study
Introduction The new WHO Labour Care Guide (LCG), also regarded as the ‘next-generation partograph’, is a core component of 2018 WHO consolidated guidelines on intrapartum care for positive childbirth experience. The Ugandan Ministry of Health is in the process of adopting the new WHO LCG with no local context-specific data to inform this transition. We will explore potential barriers and facilitators to healthcare providers’ (HCPs) sustained engagement in labour monitoring in Mbarara city, Southwestern Uganda, and use the data to refine the new WHO LCG and develop a suitable implementation strategy to ef...
Source: BMJ Open - April 15, 2024 Category: General Medicine Authors: Mugyenyi, G. R., Byamugisha, J., Tumuhimbise, W., Atukunda, E., Yarine, F. T. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research

Gastrointestinal Acute Radiation Syndrome: Mechanisms, Models, Markers, and Medical Countermeasures
This report provides an overview of information that was presented during the conference, and important discussions surrounding a broad range of topics that are critical for the research, development, licensure, and use of MCMs for GI-ARS.PMID:38616048 | DOI:10.1667/RADE-23-00196.1 (Source: Radiation Research)
Source: Radiation Research - April 14, 2024 Category: Physics Authors: Thomas A Winters Libero Marzella Olivia Molinar-Inglis Paul W Price Nyun Calvin Han Jonathan E Cohen Sue-Jane Wang Anthony F Fotenos Julie M Sullivan John Esker Paula J Lapinskas Andrea L DiCarlo Source Type: research

Results of the 2023 ISBI challenge to reduce GABA-edited MRS acquisition time
CONCLUSION: DL-based reconstruction pipelines have the promise to reduce the number of transients required for GABA-edited MRS.PMID:38613715 | DOI:10.1007/s10334-024-01156-9 (Source: Magma)
Source: Magma - April 13, 2024 Category: Radiology Authors: Rodrigo Pommot Berto Hanna Bugler Gabriel Dias Mateus Oliveira Lucas Ueda Sergio Dertkigil Paula D P Costa Leticia Rittner Julian P Merkofer Dennis M J van de Sande Sina Amirrajab Gerhard S Drenthen Mitko Veta Jacobus F A Jansen Marcel Breeuwer Ruud J G v Source Type: research

Results of the 2023 ISBI challenge to reduce GABA-edited MRS acquisition time
CONCLUSION: DL-based reconstruction pipelines have the promise to reduce the number of transients required for GABA-edited MRS.PMID:38613715 | DOI:10.1007/s10334-024-01156-9 (Source: Magma)
Source: Magma - April 13, 2024 Category: Radiology Authors: Rodrigo Pommot Berto Hanna Bugler Gabriel Dias Mateus Oliveira Lucas Ueda Sergio Dertkigil Paula D P Costa Leticia Rittner Julian P Merkofer Dennis M J van de Sande Sina Amirrajab Gerhard S Drenthen Mitko Veta Jacobus F A Jansen Marcel Breeuwer Ruud J G v Source Type: research