Development of a new phantom simulating extracellular space of tumor cell growth and cell edema for diffusion-weighted magnetic resonance imaging.
The objectives were to develop a phantom simulating various cell densities and to evaluate repeatability. MATERIALS AND METHODS: The acrylic fine particles with three different diameters were used to simulate human cells. Four-degree cell density components were developed by adjusting the volume of 10-μm particles (5, 20, 35, and 50% volume, respectively). Two-degree components to simulate cell edema were also developed by adjusting the diameter without changing number (17% and 40% volume, respectively). Spearman's rank correlation coefficient was used to find a significant correlation between apparent diffusion co...
Source: Magma - January 3, 2020 Category: Radiology Authors: Mikayama R, Yabuuchi H, Matsumoto R, Kobayashi K, Yamashita Y, Kimura M, Kamitani T, Sagiyama K, Yamasaki Y Tags: MAGMA Source Type: research

Performing IVIM-DWI using the multifunctional nanosystem for the evaluation of the antitumor microcirculation changes.
Abstract OBJECTIVES: There is a controversy about the D* and f values of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) for mid- and long-term efficacy monitoring of tumor blood perfusion. To monitor the antitumor efficacy of the F/A-PLGA@DOX/SPIO nanosystem via IVIM-DWI and to explore the value of parameters pseudo-diffusion (D*) and fraction of pseudo-diffusion (f) for evaluating therapeutic effect in non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Thirty-six A549 tumor-bearing mice were divided randomly into three groups (each n = 12). Group 1 (G1) was injected ...
Source: Magma - January 3, 2020 Category: Radiology Authors: Gao P, Liu Y, Shi C, Liu Y, Luo L Tags: MAGMA Source Type: research

Special issue on magnetic resonance imaging biomarkers of renal disease.
PMID: 31897904 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - January 3, 2020 Category: Radiology Authors: Hockings P, Laustsen C, Joles JA, Mark PB, Sourbron S Tags: MAGMA Source Type: research

Pilot study utilizing MRI 3D TGSE PASL (arterial spin labeling) differentiating clearance rates of labeled protons in the CNS of patients with early Alzheimer disease from normal subjects.
DISCUSSION: Signal decay in normal age groups correlates with decay of T1blood, thus CSF paravascular flow egresses and is inseparable from venous outflow. The AD group correlates with decay rate T1CSF, indicating a proportion of labeled blood ultra-filtered within the brain (paravascular fluid) is retained. This provides indirect evidence of reduced paravascular clearance in AD. Further development may produce an efficient biomarker identifying neurodegenerative diseases and future treatment efficacy. PMID: 31897905 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - January 3, 2020 Category: Radiology Authors: Joseph CR, Benhatzel CM, Stern LJ, Hopper OM, Lockwood MD Tags: MAGMA Source Type: research

ESMRMB Round Table report on "Can Europe Lead in Machine Learning of MRI-Data?"
ESMRMB Round Table report on "Can Europe Lead in Machine Learning of MRI-Data?" MAGMA. 2020 Jan 03;: Authors: Pizzini FB, Pesapane F, Niessen W, Geerts-Ossevoort L, Broeckx N PMID: 31897906 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - January 3, 2020 Category: Radiology Authors: Pizzini FB, Pesapane F, Niessen W, Geerts-Ossevoort L, Broeckx N Tags: MAGMA Source Type: research

Comparison of axial and coronal acquisitions by non-contrast-enhanced renal 3D MR angiography using flow-in time-spatial labeling inversion pulse.
Abstract OBJECTIVE: We evaluated image quality differences between axial and coronal non-contrast-enhanced renal three-dimensional (3D) magnetic resonance angiography (MRA) acquisitions, using time-spatial labeling inversion pulse (Time-SLIP) with flow-in balanced steady-state free precession (bSSFP). MATERIALS AND METHODS: Axial and coronal images were acquired in 128 subjects using non-contrast-enhanced 3D-MRA with Time-SLIP flow-in bSSFP on a clinical 1.5-T MRI system. Visualization of source and maximum intensity projection (MIP) images of renal arteries were compared between the axial and coronal acquisi...
Source: Magma - December 28, 2019 Category: Radiology Authors: Takahashi J, Ohmoto-Sekine Y, Yoshida T, Miyazaki M Tags: MAGMA Source Type: research

MRI for diagnosis of post-renal transplant complications: current state-of-the-art and future perspectives.
Abstract Kidney transplantation has developed into a widespread procedure to treat end stage renal failure, with transplantation results improving over the years. Postoperative complications have decreased over the past decades, but are still an important cause of morbidity and mortality. Early accurate diagnosis and treatment is the key to prevent renal allograft impairment or even graft loss. Ideally, a diagnostic tool should be able to detect post-transplant renal dysfunction, differentiate between the different causes and monitor renal function during and after therapeutic interventions. Non-invasive imaging m...
Source: Magma - December 26, 2019 Category: Radiology Authors: Schutter R, Lantinga VA, Borra RJH, Moers C Tags: MAGMA Source Type: research

Cell density quantification with TurboSPI: R2* mapping with compensation for off-resonance fat modulation.
DISCUSSION: The proposed model is a promising tool for quantitative TurboSPI R2* cell tracking, with further refinements offering the possibility of better specificity and sensitivity. PMID: 31872356 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - December 23, 2019 Category: Radiology Authors: O'Brien-Moran Z, Bowen CV, Rioux JA, Brewer KD Tags: MAGMA Source Type: research

Clinical evaluation of fully automated thigh muscle and adipose tissue segmentation using a U-Net deep learning architecture in context of osteoarthritic knee pain.
Abstract OBJECTIVE: Segmentation of thigh muscle and adipose tissue is important for the understanding of musculoskeletal diseases such as osteoarthritis. Therefore, the purpose of this work is (a) to evaluate whether a fully automated approach provides accurate segmentation of muscles and adipose tissue cross-sectional areas (CSA) compared with manual segmentation and (b) to evaluate the validity of this method based on a previous clinical study. MATERIALS AND METHODS: The segmentation method is based on U-Net architecture trained on 250 manually segmented thighs from the Osteoarthritis Initiative (OAI). The...
Source: Magma - December 23, 2019 Category: Radiology Authors: Kemnitz J, Baumgartner CF, Eckstein F, Chaudhari A, Ruhdorfer A, Wirth W, Eder SK, Konukoglu E Tags: MAGMA Source Type: research

Quantification of testicular fat deposition in the evaluation of middle-aged overweight male infertility.
Abstract OBJECTIVES: To measure the testicular volume and testicular fat deposition of middle-aged overweight men and to assess the utility of testicular fat deposition and testicular volume in determining and monitoring testicular infertility. MATERIALS AND METHODS: Pelvic MRI with thin slice T2WI, T1WI and mDIXON Quant was performed on 30 middle-aged overweight patients in the treatment group and 30 middle-aged overweight men in the control group. Testicular volume and testicular fat deposition were measured separately based on thin slice T2WI and the fat fraction (FF) map of mDIXON Quant, and the testicula...
Source: Magma - December 17, 2019 Category: Radiology Authors: Li QL, Yang F, Zhou WY, Cheng N, Tang WJ, Guo Y, Guo RM Tags: MAGMA Source Type: research

DTI of the kidney in children: comparison between normal kidneys and those with ureteropelvic junction (UPJ) obstruction.
Abstract OBJECTIVE: To compare renal diffusion tensor imaging (DTI) parameters in patients with or without ureteropelvic junction (UPJ) obstruction. METHODS: Patients that underwent functional MR urography (MRU) with renal DTI were retrospectively selected. Kidneys deemed normal on T2-weighted images and functional parameters were used as controls and compared to those kidneys with morphologic and functional findings of UPJ obstruction. DTI included a 20-direction DTI with b values of b = 0 s/mm2 and b = 400 s/mm2. Diffusion Toolkit was used for analysis and segmentation....
Source: Magma - December 16, 2019 Category: Radiology Authors: Otero HJ, Calle-Toro JS, Maya CL, Darge K, Serai SD Tags: MAGMA Source Type: research

Consensus-based technical recommendations for clinical translation of renal ASL MRI.
This study aimed at developing technical recommendations for the acquisition, processing and analysis of renal ASL data in the human kidney at 1.5 T and 3 T field strengths that can promote standardization of renal perfusion measurements and facilitate the comparability of results across scanners and in multi-centre clinical studies. METHODS: An international panel of 23 renal ASL experts followed a modified Delphi process, including on-line surveys and two in-person meetings, to formulate a series of consensus statements regarding patient preparation, hardware, acquisition protocol, analysis steps and data ...
Source: Magma - December 12, 2019 Category: Radiology Authors: Nery F, Buchanan CE, Harteveld AA, Odudu A, Bane O, Cox EF, Derlin K, Gach HM, Golay X, Gutberlet M, Laustsen C, Ljimani A, Madhuranthakam AJ, Pedrosa I, Prasad PV, Robson PM, Sharma K, Sourbron S, Taso M, Thomas DL, Wang DJJ, Zhang JL, Alsop DC, Fain SB, Tags: MAGMA Source Type: research

Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients.
Abstract OBJECTIVE: To assess interobserver reproducibility of different regions of interest (ROIs) on multi-parametric renal MRI using commercially available software. MATERIALS AND METHODS: Healthy volunteers (HV), patients with heart failure (HF) and renal transplant recipients (Tx) were recruited. Localiser scans, T1 mapping and pseudo-continuous arterial spin labelling (pCASL) were performed. HV and Tx also underwent diffusion-weighted imaging to allow calculation of apparent diffusion coefficient (ADC). For T1, pCASL and ADC, ROIs were drawn for whole kidney (WK), cortex (Cx), user-defined representativ...
Source: Magma - December 10, 2019 Category: Radiology Authors: Rankin AJ, Allwood-Spiers S, Lee MMY, Zhu L, Woodward R, Kuehn B, Radjenovic A, Sattar N, Roditi G, Mark PB, Gillis KA Tags: MAGMA Source Type: research

Renal BOLD MRI in patients with chronic kidney disease: comparison of the semi-automated twelve layer concentric objects (TLCO) and manual ROI methods.
DISCUSSION: There was a high degree of agreement between the two methods in terms of regional R2* measurements and both methods did not show differences between moderate CKD patients and controls. However, R2*_Slope and Δ(R2*_Slope) showed the largest sensitivity in distinguishing CKD from controls. PMID: 31823276 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - December 10, 2019 Category: Radiology Authors: Li LP, Milani B, Pruijm M, Kohn O, Sprague S, Hack B, Prasad P Tags: MAGMA Source Type: research

Stability evaluation of Gd chelates for macromolecular MRI contrast agents.
DISCUSSION: Our macromolecular design was considered to work well for high Gd3+-chelate stability. PMID: 31823277 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - December 10, 2019 Category: Radiology Authors: Yokoyama M, Shiraishi K Tags: MAGMA Source Type: research

Comparison of multi-delay FAIR and pCASL labeling approaches for renal perfusion quantification at 3T MRI.
This study showed that compared to (balanced) pCASL, FAIR perfusion values were significantly higher and more comparable between visits. PMID: 31811490 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - December 6, 2019 Category: Radiology Authors: Harteveld AA, de Boer A, Franklin SL, Leiner T, van Stralen M, Bos C Tags: MAGMA Source Type: research

Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei.
Abstract Hyperpolarization is an emerging method in magnetic resonance imaging that allows nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six orders of magnitude at clinically relevant field strengths and administered at high concentration to a subject at the time of measurement. This transient gain in signal has enabled the non-invasive detection and imaging of gas ventilation and diffusion in the lungs, perfusion in blood vessels and tissues, and metabolic conversion in cells, animals, and patients. The rapid development of this method is based on advances in polar...
Source: Magma - December 6, 2019 Category: Radiology Authors: Topping GJ, Hundshammer C, Nagel L, Grashei M, Aigner M, Skinner JG, Schulte RF, Schilling F Tags: MAGMA Source Type: research

Cardiorenal sodium MRI in small rodents using a quadrature birdcage volume resonator at 9.4  T.
DISCUSSION: These initial results obtained in vivo in rats using the quadrature birdcage volume RF resonator for 23Na MRI permit dedicated studies on experimental models of cardiac and renal diseases, which would contribute to translational research of the cardiorenal syndrome. PMID: 31797228 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - December 3, 2019 Category: Radiology Authors: Boehmert L, Waiczies H, Kuehne A, Oezerdem C, Waiczies S, Starke L, Ku MC, Pohlmann A, Seeliger E, Niendorf T Tags: MAGMA Source Type: research

Comparison between synthetic and conventional magnetic resonance imaging in patients with multiple sclerosis and controls.
CONCLUSIONS: SyMRI can be used in clinical practice because it has a similar diagnostic accuracy which reduces the scanning time compared to the conventional one. However, synthetic T2-FLAIR images need to be improved. PMID: 31782035 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - November 28, 2019 Category: Radiology Authors: Di Giuliano F, Minosse S, Picchi E, Marfia GA, Da Ros V, Muto M, Muto M, Pistolese CA, Laghi A, Garaci F, Floris R Tags: MAGMA Source Type: research

Hyperpolarised 13C-MRI metabolic and functional imaging: an emerging renal MR diagnostic modality.
Abstract Magnetic resonance imaging (MRI) is a well-established modality for assessing renal morphology and function, as well as changes that occur during disease. However, the significant metabolic changes associated with renal disease are more challenging to assess with MRI. Hyperpolarized carbon-13 MRI is an emerging technique which provides an opportunity to probe metabolic alterations at high sensitivity by providing an increase in the signal-to-noise ratio of 20,000-fold or more. This review will highlight the current status of hyperpolarised 13C-MRI and its translation into the clinic and how it compares to...
Source: Magma - November 28, 2019 Category: Radiology Authors: Pedersen M, Ursprung S, Jensen JD, Jespersen B, Gallagher F, Laustsen C Tags: MAGMA Source Type: research

Diffusion tensor imaging of the human thigh: consideration of DTI-based fiber tracking stop criteria.
Abstract OBJECTIVES: To consider the tract-based analysis of DTI parameters in human muscle by assessing different fiber tracking stop criteria settings on diffusion parameters. MATERIALS AND METHODS: 30 healthy volunteers underwent a 3 T MRI. Diffusion-weighted images were acquired to perform DTI and fiber tracking analysis for six thigh muscles. Whole thigh muscles were evaluated by fiber tractography using different fiber tracking stop parameters [FA (0.01-0.15) to (0.4-0.99); angle 10°-30°, step size 0.75 mm, 1.5 mm, 3 mm]. Diffusion and tractography-derived parameters per stop...
Source: Magma - November 27, 2019 Category: Radiology Authors: Forsting J, Rehmann R, Froeling M, Vorgerd M, Tegenthoff M, Schlaffke L Tags: MAGMA Source Type: research

Consensus-based technical recommendations for clinical translation of renal BOLD MRI.
ST, Sourbron S, Pohlmann A, Fain SB, Prasad PV Abstract Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative provides technical recommendations based on a consensus report with the aim to move towards standardized protocols that facilitate clinical translation and comparison of data across sites. We used a recently published systematic review paper, which included a detailed summary of renal BOLD MRI technical parameters and areas of investigation in its supplementary material, as the starting point in developing...
Source: Magma - November 25, 2019 Category: Radiology Authors: Bane O, Mendichovszky IA, Milani B, Dekkers IA, Deux JF, Eckerbom P, Grenier N, Hall ME, Inoue T, Laustsen C, Lerman LO, Liu C, Morrell G, Pedersen M, Pruijm M, Sadowski EA, Seeliger E, Sharma K, Thoeny H, Vermathen P, Wang ZJ, Serafin Z, Zhang JL, Franci Tags: MAGMA Source Type: research

Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI.
Abstract To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was exp...
Source: Magma - November 22, 2019 Category: Radiology Authors: Dekkers IA, de Boer A, Sharma K, Cox EF, Lamb HJ, Buckley DL, Bane O, Morris DM, Prasad PV, Semple SIK, Gillis KA, Hockings P, Buchanan C, Wolf M, Laustsen C, Leiner T, Haddock B, Hoogduin JM, Pullens P, Sourbron S, Francis S Tags: MAGMA Source Type: research

Diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy: a comparison of motion-compensated spin echo and stimulated echo techniques.
Abstract OBJECTIVES: Diffusion tensor cardiovascular magnetic resonance (DT-CMR) interrogates myocardial microstructure. Two frequently used in vivo DT-CMR techniques are motion-compensated spin echo (M2-SE) and stimulated echo acquisition mode (STEAM). Whilst M2-SE is strain-insensitive and signal to noise ratio efficient, STEAM has a longer diffusion time and motion compensation is unnecessary. Here we compare STEAM and M2-SE DT-CMR in patients. MATERIALS AND METHODS: Biphasic DT-CMR using STEAM and M2-SE, late gadolinium imaging and pre/post gadolinium T1-mapping were performed in a mid-vent...
Source: Magma - November 22, 2019 Category: Radiology Authors: Khalique Z, Scott AD, Ferreira PF, Nielles-Vallespin S, Firmin DN, Pennell DJ Tags: MAGMA Source Type: research

Respiratory motion-corrected, compressively sampled dynamic MR image reconstruction by exploiting multiple sparsity constraints and phase correlation-based data binning.
CONCLUSION: The proposed method achieves significant improvement in the AP and RMSE values at different AFs for both the phantom and in vivo data. PMID: 31754909 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - November 21, 2019 Category: Radiology Authors: Najeeb F, Usman M, Aslam I, Qazi SA, Omer H Tags: MAGMA Source Type: research

Modeling radiofrequency responses of realistic multi-electrode leads containing helical and straight wires.
CONCLUSION: These results highlight the need to evaluate a LEM for each electrode of a multi-electrode lead as well as for each possible surrounding medium. It is also shown that the results derived from simulations based on simplified single-electrode leads can significantly mislead multi-electrode lead analyses. PMID: 31745756 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - November 19, 2019 Category: Radiology Authors: Kozlov M, Horner M, Kainz W Tags: MAGMA Source Type: research

A hybrid (iron-fat-water) phantom for liver iron overload quantification in the presence of contaminating fat using magnetic resonance imaging.
This study proposes a phantom design concomitantly containing various concentrations of iron and fat suitable for devising accurate simultaneous T2* and fat quantification technique. MATERIALS AND METHODS: A 46-vial iron-fat-water phantom with various iron concentrations covering clinically relevant T2* relaxation time values, from healthy to severely overloaded liver and wide fat percentages ranges from 0 to 100% was prepared. The phantom was constructed using insoluble iron (II, III) oxide powder containing microscale particles. T2*-weighted imaging using multi-gradient-echo (mGRE) sequence, and chemical shift imagi...
Source: Magma - November 16, 2019 Category: Radiology Authors: Mobini N, Malekzadeh M, Haghighatkhah H, Saligheh Rad H Tags: MAGMA Source Type: research

Multi-stage automated local arterial input function selection in perfusion MRI.
CONCLUSION: The results suggest the proposed solution provides a more robust approach to perfusion quantification than currently available fully automated local AIF methods. PMID: 31722036 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - November 13, 2019 Category: Radiology Authors: Tabbara R, Connelly A, Calamante F Tags: MAGMA Source Type: research

Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI.
DISCUSSION: The consensus-based technical recommendations for renal DWI aim to facilitate inter-site harmonization and increase clinical impact of the technique on a larger scale by setting a framework for acquisition protocols for future renal DWI studies. We anticipate an iterative process with continuous updating of the recommendations according to progress in the field. PMID: 31676990 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - November 1, 2019 Category: Radiology Authors: Ljimani A, Caroli A, Laustsen C, Francis S, Mendichovszky IA, Bane O, Nery F, Sharma K, Pohlmann A, Dekkers IA, Vallee JP, Derlin K, Notohamiprodjo M, Lim RP, Palmucci S, Serai SD, Periquito J, Wang ZJ, Froeling M, Thoeny HC, Prasad P, Schneider M, Niendo Tags: MAGMA Source Type: research

Correction to: Semi-automatic segmentation from intrinsically-registered 18F-FDG-PET/MRI for treatment response assessment in a breast cancer cohort: comparison to manual DCE-MRI.
, Jerome NP Abstract The original version of this article unfortunately contained a mistake in Fig. 6. PMID: 31664580 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 29, 2019 Category: Radiology Authors: Andreassen MMS, Goa PE, Sjøbakk TE, Hedayati R, Eikesdal HP, Deng C, Østlie A, Lundgren S, Bathen TF, Jerome NP Tags: MAGMA Source Type: research

Dynamic MR imaging of the skeletal muscle in young and senior volunteers during synchronized minimal neuromuscular electrical stimulation.
In conclusion, NMES-synchronized MRI could be successfully applied in senior volunteers with strain results clearly different from the younger volunteers. Also, differences within the senior group were detected both in the magnitude of strain and in the position of maximum strain pixels. PMID: 31650419 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 24, 2019 Category: Radiology Authors: Deligianni X, Klenk C, Place N, Garcia M, Pansini M, Hirschmann A, Schmidt-Trucksäss A, Bieri O, Santini F Tags: MAGMA Source Type: research

Measuring geometric accuracy in magnetic resonance imaging with 3D-printed phantom and nonrigid image registration.
DISCUSSION: Using nonrigid CT-MR registration can provide a robust and relatively test-object-agnostic method for estimating the intra- and inter-scanner variations of the geometric distortions. PMID: 31646408 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 23, 2019 Category: Radiology Authors: Nousiainen K, Mäkelä T Tags: MAGMA Source Type: research

Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA.
CONCLUSION: The process generated meaningful technical recommendations across very different MRI methods, while allowing for improvement and refinement as open issues are resolved. The results are likely to be widely supported by the renal MRI community and thereby promote more harmonisation. PMID: 31628564 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 18, 2019 Category: Radiology Authors: Mendichovszky I, Pullens P, Dekkers I, Nery F, Bane O, Pohlmann A, de Boer A, Ljimani A, Odudu A, Buchanan C, Sharma K, Laustsen C, Harteveld A, Golay X, Pedrosa I, Alsop D, Fain S, Caroli A, Prasad P, Francis S, Sigmund E, Fernández-Seara M, Sourbron S Tags: MAGMA Source Type: research

Intravascular signal suppression and microvascular signal mapping using delays alternating with nutation for tailored excitation (DANTE) pulse for arterial spin labeling perfusion imaging.
DISCUSSION: An optimized DANTE makes it possible to efficiently suppress the macro-and-micro vascular signals depending on the flow velocity. Moreover, macrovascular signal mapping may be useful to assess altered hemodynamic states. PMID: 31625029 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 17, 2019 Category: Radiology Authors: Fujiwara Y, Kimura H, Ishida S, Kanamoto M, Takei N, Matsuda T, Kosaka N, Adachi T Tags: MAGMA Source Type: research

Quantification of sodium T1 in abdominal tissues at 3  T.
DISCUSSION: 23Na-T1 quantification using a SR-TrueFISP is feasible in clinical settings, in the images constrained by clinically applicable acquisition time of reduced spatial resolution or averages. PMID: 31625030 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 17, 2019 Category: Radiology Authors: Gomolka RS, Ciritsis A, Meier A, Rossi C Tags: MAGMA Source Type: research

Determination of oxygen r1 at 3 Tesla using samples with a concentration range of dissolved oxygen.
CONCLUSION: MOLLI T1-mapping sequences may be used for detecting dissolved oxygen in vivo at 3 T with an [Formula: see text] in the range 4.18-4.8 × 10-3 s-1 mg-1 L and a corresponding LOD for dissolved oxygen of approximately 10 mg L-1. MOLLI-based T1 mapping may be a useful non-invasive tool for quantification of in vivo changes of DO concentration during oxygen challenges. PMID: 31606810 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 12, 2019 Category: Radiology Authors: Vatnehol SAS, Hol PK, Bjørnerud A, Amiry-Moghaddam M, Haglerød C, Storås TH Tags: MAGMA Source Type: research

Image registration in dynamic renal MRI-current status and prospects.
Rogelj P Abstract Magnetic resonance imaging (MRI) modalities have achieved an increasingly important role in the clinical work-up of chronic kidney diseases (CKD). This comprises among others assessment of hemodynamic parameters by arterial spin labeling (ASL) or dynamic contrast-enhanced (DCE-) MRI. Especially in the latter, images or volumes of the kidney are acquired over time for up to several minutes. Therefore, they are hampered by motion, e.g., by pulsation, peristaltic, or breathing motion. This motion can hinder subsequent image analysis to estimate hemodynamic parameters like renal blood flow or glomer...
Source: Magma - October 9, 2019 Category: Radiology Authors: Zöllner FG, Šerifović-Trbalić A, Kabelitz G, Kociński M, Materka A, Rogelj P Tags: MAGMA Source Type: research

An MRI study of solute transport in the intervertebral disc.
CONCLUSION: The MRI technique provides high-quality quantitative data which correspond well to theoretical predictions, allowing values for partition coefficient and time constant to be readily determined. These measurements provide information to underpin similar studies in vivo and may be used as a model for the transport of nutrients and pharmaceutical agents in the disc. PMID: 31586265 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - October 4, 2019 Category: Radiology Authors: Palfrey RM, Summers IR, Winlove CP Tags: MAGMA Source Type: research

Severe pulmonary regurgitation in adolescents with tetralogy of Fallot leads to increased longitudinal strain.
kinen E Abstract OBJECTIVES: Postoperative patients with tetralogy of Fallot (TOF) are often compromised by chronic pulmonary regurgitation and chronic right ventricular volume load. We sought to determine whether pulmonary regurgitation (PR) would affect right and left ventricle (RV and LV) strain. MATERIALS AND METHODS: This cross-sectional analysis included 40 patients who had TOF with surgical repair, with an average follow-up period of 11.8 ± 3.0 years. Altogether, 44 healthy volunteers with similar age and gender distribution were recruited. A cardiovascular magnetic resonance ...
Source: Magma - October 3, 2019 Category: Radiology Authors: Ylitalo P, Lehmonen L, Lauerma K, Holmström M, Pitkänen-Argillander O, Jokinen E Tags: MAGMA Source Type: research

Optimization of intravoxel incoherent motion (IVIM): variability of parameters measurements using a reduced distribution of b values for breast tumors analysis.
This study aimed to examine the variability of intravoxel incoherent motion measurements acquired from reduced distributions of b values for breast tumors analysis. MATERIALS AND METHODS: The investigations were carried out on twenty-four patients with diagnosed breast tumors. A conventional unenhanced MRI and various IVIM series preset with different distributions of b values (0-1000 s/mm2) were performed. We assessed the variability in Dslow, Dfast, and PF measurements for different distributions of 9 to 4 b values compared with the IVIM metrics for 10 b values using Wilcoxon-Signed rank test. The data was stat...
Source: Magma - September 30, 2019 Category: Radiology Authors: Doudou NR, Liu Y, Kampo S, Zhang K, Dai Y, Wang S Tags: MAGMA Source Type: research

Semi-automatic segmentation from intrinsically-registered 18F-FDG-PET/MRI for treatment response assessment in a breast cancer cohort: comparison to manual DCE-MRI.
DISCUSSION: Using PET/MRI, tumor area and mean ADC value estimated with a GMM-PET can replicate manual DCE tumor definition from MRI for monitoring neoadjuvant treatment response in breast cancer. PMID: 31562584 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - September 27, 2019 Category: Radiology Authors: Andreassen MMS, Goa PE, Sjøbakk TE, Hedayati R, Eikesdal HP, Deng C, Østlie A, Lundgren S, Bathen TF, Jerome NP Tags: MAGMA Source Type: research

The reproducibility of measurements using a standardization phantom for the evaluation of fractional anisotropy (FA) derived from diffusion tensor imaging (DTI).
DISCUSSION: High reproducibility of measurements using a standardization phantom for the evaluation of FA was achieved. PMID: 31552552 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - September 24, 2019 Category: Radiology Authors: Kimura M, Yabuuchi H, Matsumoto R, Kobayashi K, Yamashita Y, Nagatomo K, Mikayama R, Kamitani T, Sagiyama K, Yamasaki Y Tags: MAGMA Source Type: research

Histogram analysis of apparent diffusion coefficients for predicting pelvic lymph node metastasis in patients with uterine cervical cancer.
Abstract OBJECTIVE: To investigate the value of apparent diffusion coefficient (ADC) histogram analysis in predicting pelvic lymph node (LN) metastasis in patients with cervical cancer undergoing surgery. MATERIALS AND METHODS: A total of 162 cervical cancer patients who underwent radical abdominal hysterectomy with pelvic LN dissection performed with pelvic 3 T-MRI including diffusion-weighted imaging were enrolled in this study. The ADC histogram variables (minimum, mean, median, 97.5th percentile [ADC97.5], and maximum) of the tumors were developed using in-house software. For predicting pelvic LN met...
Source: Magma - September 23, 2019 Category: Radiology Authors: Lee J, Kim CK, Park SY Tags: MAGMA Source Type: research

Quantitative analysis of fetal magnetic resonance phantoms and recommendations for an anthropomorphic motion phantom.
DISCUSSION: Currently available fetal phantoms lack accuracy and motion simulation. 3D printing may lead to higher accuracy compared with traditional manufacturing. Future research needs to focus on properly simulating both fetal anatomy and physiological motion to produce a phantom that is appropriate for fetal MRI sequence development and optimization. PMID: 31487004 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - September 5, 2019 Category: Radiology Authors: Shulman M, Cho E, Aasi B, Cheng J, Nithiyanantham S, Waddell N, Sussman D Tags: MAGMA Source Type: research

A quantitative alternative to the Goutallier classification system using Lava Flex and Ideal MRI techniques: volumetric intramuscular fatty infiltration of the supraspinatus muscle, a cadaveric study.
DISCUSSION: The Lava Flex technique, taking about 30% of the acquisition time, may prevent motion artifacts in outcomes associated with the longer Ideal IQ technique. However, potential magnetic field inhomogeneities should be considered. The Lava Flex technique may be a faster and valid alternative to the Goutallier classification system. PMID: 31486009 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - September 4, 2019 Category: Radiology Authors: Trevino JH, Gorny KR, Gomez-Cintron A, Zhao C, Giambini H Tags: MAGMA Source Type: research

Renal sinus fat and renal hemodynamics: a cross-sectional analysis.
CONCLUSIONS: In T2D patients, higher RSF volume was negatively associated to GFR. In addition, RSF volume was positively associated with increased renal vascular resistance, which may mediate hypertension and CKD development. Further research is needed to investigate how RSF may alter the (afferent) vascular resistance of the renal vasculature. PMID: 31471702 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - August 31, 2019 Category: Radiology Authors: Spit KA, Muskiet MHA, Tonneijck L, Smits MM, Kramer MHH, Joles JA, de Boer A, van Raalte DH Tags: MAGMA Source Type: research

Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper.
DISCUSSION: Renal PC-MRI shows promise as a non-invasive technique to reliably measure RBF, both in healthy volunteers and in patients with renal disease. Future multicentric studies are needed to provide definitive normative ranges and to demonstrate the clinical potential of PC-MRI, likely as part of a multi-parametric renal MRI protocol. PMID: 31422518 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - August 17, 2019 Category: Radiology Authors: Villa G, Ringgaard S, Hermann I, Noble R, Brambilla P, Khatir DS, Zöllner FG, Francis ST, Selby NM, Remuzzi A, Caroli A Tags: MAGMA Source Type: research

The advantages of radial trajectories for vessel-selective dynamic angiography with arterial spin labeling.
Abstract OBJECTIVES: To demonstrate the advantages of radial k-space trajectories over conventional Cartesian approaches for accelerating the acquisition of vessel-selective arterial spin labeling (ASL) dynamic angiograms, which are conventionally time consuming to acquire. MATERIALS AND METHODS: Vessel-encoded pseudocontinuous ASL was combined with time-resolved balanced steady-state free precession (bSSFP) and spoiled gradient echo (SPGR) readouts to obtain dynamic vessel-selective angiograms arising from the four main brain-feeding arteries. Dynamic 2D protocols with acquisition times of one minute or less...
Source: Magma - August 17, 2019 Category: Radiology Authors: Berry ESK, Jezzard P, Okell TW Tags: MAGMA Source Type: research

Inductive measurement and encoding of k-space trajectories in MR raw data.
The objective of this study was to concurrently acquire an inductive k-space trajectory measure and corresponding imaging data by an MR scanner. MATERIALS AND METHODS:  1D gradient measures were obtained by digital integration, regularized using measured gradient coil currents and recorded individually by the scanner concurrently with raw MR data. Gradient measures were frequency modulated into an RF signal receivable by the scanner, yielding a k-space trajectory measure from the cumulative phase of the acquired data. Generation of the gradient measure and frequency modulation was performed by previously develope...
Source: Magma - July 30, 2019 Category: Radiology Authors: Pedersen JO, Hanson CG, Xue R, Hanson LG Tags: MAGMA Source Type: research

Transverse relaxometry with transmit field-constrained stimulated echo compensation.
DISCUSSION: The proposed method generates reliable and reproducible quantitative T2 maps and should be considered for future relaxometry studies. PMID: 31338627 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - July 23, 2019 Category: Radiology Authors: Basiri R, Federico P, Lebel RM Tags: MAGMA Source Type: research