Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR.
DISCUSSION: Three metabolic pathways can be probed simultaneously in the mouse liver in vivo, in real time,  using hyperpolarized DHAc. PMID: 32910316 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - September 10, 2020 Category: Radiology Authors: Marco-Rius I, Wright AJ, Hu DE, Savic D, Miller JJ, Timm KN, Tyler D, Brindle KM, Comment A Tags: MAGMA Source Type: research

Detecting small pulmonary nodules with spiral ultrashort echo time sequences in 1.5  T MRI.
This study investigated ultrashort echo time (UTE) sequences in 1.5 T magnetic resonance imaging (MRI) for small lung nodule detection. MATERIALS AND METHODS: A total of 120 patients with 165 small lung nodules before video-associated thoracoscopic resection were enrolled. MRI sequences included conventional volumetric interpolated breath-hold examination (VIBE, scan time 16 s), spiral UTE (TE 0.05 ms) with free-breathing (scan time 3.5-5 min), and breath-hold sequences (scan time 20 s). Chest CT provided a standard reference for nodule size and morphology. Nodule detection sensitivity was eva...
Source: Magma - September 9, 2020 Category: Radiology Authors: Huang YS, Niisato E, Su MM, Benkert T, Hsu HH, Shih JY, Chen JS, Chang YC Tags: MAGMA Source Type: research

Contrast optimization in arterial spin labeling with multiple post-labeling delays for cerebrovascular assessment.
CONCLUSION: We successfully assessed brain perfusion of patients with asymptomatic CAS using multi-PLD ASL with FA sweep. We were able to show subtle individual differences. Moreover, prolonged arterial transit time in patients was observed, although they were considered asymptomatic, suggesting that it may not be an adequate term to characterize them. PMID: 32885356 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - September 3, 2020 Category: Radiology Authors: Paschoal AM, Leoni RF, Foerster BU, Dos Santos AC, Pontes-Neto OM, Paiva FF Tags: MAGMA Source Type: research

On the reproducibility of hippocampal MEGA-sLASER GABA MRS at 7T using an optimized analysis pipeline.
CONCLUSION: The increased spectral dispersion of ultra-high-field spectroscopy allows for reproducible spectral quantification, despite a very broad line width. The achieved reproducibility enables the routine use of hippocampal GABA spectroscopy at 7 Tesla. PMID: 32865653 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - August 31, 2020 Category: Radiology Authors: Völzke Y, Pracht ED, Hattingen E, Y Tse DH, Stöcker T Tags: MAGMA Source Type: research

Routine sagittal whole-spine magnetic resonance imaging in finding incidental spine lesions.
Abstract PURPOSE: To examine the efficacy and feasibility of T2-weighted whole-spine sagittal magnetic resonance imaging (MRI) screening for all patients who undergo MRI of the lumbar spine for any indication. METHODS: A review of 1145 consecutive T2-weighted whole-spine sagittal MRI screening sequences performed for lumbar spine imaging was undertaken for the purposes of documenting the incidence and clinical significance of thoracic and cervical spine incidental findings, as well as to establish correlation between these pathologies and those found in the lumbar spine. RESULTS: Out of the 1145 patients...
Source: Magma - August 12, 2020 Category: Radiology Authors: Smorgick Y, Granek T, Mirovsky Y, Rabau O, Anekstein Y, Tal S Tags: MAGMA Source Type: research

OPERA: a  novel method to reduce ghost and aliasing artifacts.
OPERA: a novel method to reduce ghost and aliasing artifacts. MAGMA. 2020 Aug 12;: Authors: Dell'Orso A, Positano V, Arisi G, d'Errico F, Taddei A, Banchi B, De Felice C Abstract OBJECTIVE: A method for Orthogonal Phase Encoding Reduction of Artifact (OPERA) was developed and tested. MATERIALS AND METHODS: Because the position of ghosts and aliasing artifacts is predictable along columns or rows, OPERA combines the intensity values of two images acquired using the same parameters, but with swapped phase-encoding directions, to correct the artifacts. Simulations and phantom experiments were c...
Source: Magma - August 12, 2020 Category: Radiology Authors: Dell'Orso A, Positano V, Arisi G, d'Errico F, Taddei A, Banchi B, De Felice C Tags: MAGMA Source Type: research

Does the brain have mechanical compliance?
PMID: 32770369 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - August 8, 2020 Category: Radiology Authors: Alperin N Tags: MAGMA Source Type: research

Segmentation of the fascia lata and reproducible quantification of intermuscular adipose tissue (IMAT) of the thigh.
DISCUSSION: The FL segmentation is an important step to quantify IMAT with high precision and may be useful to investigate effects of aging and treatment on changes of IMAT and FF. ClinicalTrials.gov identifier NCT2857660, August 5, 2016. TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT2857660, August 5, 2016. PMID: 32761398 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - August 6, 2020 Category: Radiology Authors: Chaudry O, Friedberger A, Grimm A, Uder M, Nagel AM, Kemmler W, Engelke K Tags: MAGMA Source Type: research

Automated reference tissue normalization of T2-weighted MR images of the prostate using object recognition.
ot M Abstract OBJECTIVES: To develop and evaluate an automated method for prostate T2-weighted (T2W) image normalization using dual-reference (fat and muscle) tissue. MATERIALS AND METHODS: Transverse T2W images from the publicly available PROMISE12 (N = 80) and PROSTATEx (N = 202) challenge datasets, and an in-house collected dataset (N = 60) were used. Aggregate channel features object detectors were trained to detect reference fat and muscle tissue regions, which were processed and utilized to normalize the 3D images by linear scaling. Mean prostate pseudo T2 value...
Source: Magma - July 31, 2020 Category: Radiology Authors: Sunoqrot MRS, Nketiah GA, Selnæs KM, Bathen TF, Elschot M Tags: MAGMA Source Type: research

Diffusion-weighted imaging in the assessment of renal function in patients with diabetes mellitus type 2.
Abstract OBJECTIVE: Investigation of functional magnetic resonance (MR) imaging role in early diagnosis of diabetic nephropathy (DN) in patients with diabetes mellitus (DM) type 2, by quantification of the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values. MATERIAL AND METHODS: 10 healthy volunteers and 91 DM type 2 patients were scanned using diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) sequences. Patients were divided into four groups based on the estimated glomerular filtration value (eGFR). ADC and FA values, calculated in six regions of interest in each kid...
Source: Magma - July 30, 2020 Category: Radiology Authors: Mrđanin T, Nikolić O, Molnar U, Mitrović M, Till V Tags: MAGMA Source Type: research

In vitro real-time magnetic resonance imaging for quantification of thrombosis.
Abstract OBJECTIVES: Thrombosis is a leading cause of failure for cardiovascular devices. While computational simulations are a powerful tool to predict thrombosis and evaluate the risk for medical devices, limited experimental data are available to validate the simulations. The aim of the current study is to provide experimental data of a growing thrombus for device-induced thrombosis. MATERIALS AND METHODS: Thrombosis within a backward-facing step (BFS), or sudden expansion was investigated, using bovine and human blood circulated through the BFS model for 30 min, with a constant inflow rate of 0.76 L/...
Source: Magma - July 29, 2020 Category: Radiology Authors: Yang L, Neuberger T, Manning KB Tags: MAGMA Source Type: research

Detection of early cartilage degeneration in the tibiotalar joint using 3 T gagCEST imaging: a feasibility study.
z A Abstract OBJECTIVE: To establish and optimize a stable 3 Tesla (T) glycosaminoglycan chemical exchange saturation transfer (gagCEST) imaging protocol for assessing the articular cartilage of the tibiotalar joint in healthy volunteers and patients after a sustained injury to the ankle. METHODS: Using Bloch-McConnell simulations, we optimized the sequence protocol for a 3 T MRI scanner for maximum gagCEST effect size within a clinically feasible time frame of less than 07:30 min. This protocol was then used to analyze the gagCEST effect of the articular cartilage of the tibiotalar joint of 17 healthy v...
Source: Magma - July 28, 2020 Category: Radiology Authors: Abrar DB, Schleich C, Radke KL, Frenken M, Stabinska J, Ljimani A, Wittsack HJ, Antoch G, Bittersohl B, Hesper T, Nebelung S, Müller-Lutz A Tags: MAGMA Source Type: research

Disrupted white matter connectivity and organization of brain structural connectomes in tuberous sclerosis complex patients with neuropsychiatric disorders using diffusion tensor imaging.
Abstract OBJECTIVE: Tuberous sclerosis complex (TSC) is a genetic neurocutaneous syndrome with variable and unpredictable neurological comorbidity that includes epilepsy, intellectual disability (ID), autism spectrum disorder, and neurobehavioral abnormalities. The degree of white matter involvement is believed to be associated with the severity of neurological impairment. The goal of the present study was to evaluate diffusion characteristics of tubers, white matter lesions, and brain structural network alterations in TSC patients using diffusion tensor imaging (DTI), graph theoretical analysis (GTA), and network...
Source: Magma - July 26, 2020 Category: Radiology Authors: Tsai JD, Ho MC, Lee HY, Shen CY, Li JY, Weng JC Tags: MAGMA Source Type: research

Interactive tool to create adjustable anatomical atlases for mouse brain imaging.
Abstract OBJECTIVE: Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics. RESULT: To overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain a...
Source: Magma - July 21, 2020 Category: Radiology Authors: Sack M, Zheng L, Gass N, Ende G, Sartorius A, Weber-Fahr W Tags: MAGMA Source Type: research

Combine contrast-enhanced 3D T2-weighted short inversion time inversion recovery MR neurography with MR angiography at 1.5  T in the assessment of brachial plexopathy.
Combine contrast-enhanced 3D T2-weighted short inversion time inversion recovery MR neurography with MR angiography at 1.5 T in the assessment of brachial plexopathy. MAGMA. 2020 Jul 13;: Authors: Xu Z, Zhang T, Chen J, Liu Z, Wang T, Hu Y, Zhang J, Xue F Abstract PURPOSE: To explore the benefits of using a single injection of contrast agent at a 1.5 T system to perform both contrast-enhanced MR angiography (MRA) and 3D-T2-STIR MR neurography (MRN) to assess of brachial plexopathy. METHODS: In this prospective study, 27 patients with suspected brachial plexopathy, received an imaging pr...
Source: Magma - July 13, 2020 Category: Radiology Authors: Xu Z, Zhang T, Chen J, Liu Z, Wang T, Hu Y, Zhang J, Xue F Tags: MAGMA Source Type: research

Altered spontaneous brain activity in essential tremor with and without resting tremor: a resting-state fMRI study.
This study aims to use resting-state functional magnetic resonance imaging (rs-fMRI) to explore the alterations of brain activity between the drug-naïve patients of rET and ETwr. METHODS: We recruited 19 patients with rET, 31 patients with ETwr and 25 healthy controls (HCs) to undergo a 3.0-T rs-fMRI examination. The differences of regional brain spontaneous activity between the rET, ETwr and HCs, as well as between total ET (rET + ETwr) and HCs were measured by amplitude of low-frequency fluctuation (ALFF) and fractional ALFF (fALFF). The relationships between the altered brain measurements and the...
Source: Magma - July 13, 2020 Category: Radiology Authors: Li JY, Suo XL, Li NN, Lei D, Lu ZJ, Wang L, Peng JX, Duan LR, Jing-Xi, Yi-Jiang, Gong QY, Peng R Tags: MAGMA Source Type: research

Characterization of hardware-related spatial distortions for IR-PETRA pulse sequence using a brain specific phantom.
DISCUSSION: The spatial accuracy of MR images, besides being impacted by hardware performance, scanner capabilities, and imaging parameters, is mainly affected by its imaging strategy and data acquisition scheme. In 3.0 T, even without applying vendor correction algorithms, spatial accuracy of IR-PETRA image is sufficient for generating pseudo-CTs. In 1.5 T, distortion-correction is required to provide this accuracy. PMID: 32632747 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - July 6, 2020 Category: Radiology Authors: Ahmadian S, Jabbari I, Bagherimofidi SM, Saligheh Rad H Tags: MAGMA Source Type: research

Application of a stretched-exponential model for morphometric analysis of accelerated diffusion-weighted 129Xe MRI of the rat lung.
Abstract OBJECTIVE: Diffusion-weighted, hyperpolarized 129Xe MRI is useful for the characterization of microstructural changes in the lung. A stretched exponential model was proposed for morphometric extraction of the mean chord length (Lm) from diffusion-weighted data. The stretched exponential model enables accelerated mapping of Lm in a single-breathhold using compressed sensing. Our purpose was to compare Lm maps obtained from stretched-exponential model analysis of accelerated versus unaccelerated diffusion-weighted 129Xe MRI data obtained from healthy/injured rat lungs. MATERIAL AND METHODS: Lm maps wer...
Source: Magma - July 6, 2020 Category: Radiology Authors: Ouriadov AV, Fox MS, Lindenmaier AA, Stirrat E, Serrai H, Santyr G Tags: MAGMA Source Type: research

Comparison of models of diffusion in Wilms' tumours and normal contralateral renal tissue.
This study aimed to compare the suitability of four diffusion models (mono exponential, IVIM [Intravoxel Incoherent Motion], stretched exponential, and kurtosis) in Wilms' tumours and the unaffected contralateral kidneys. MATERIALS AND METHODS: DWI data were retrospectively reviewed (110 Wilms' tumours and 75 normal kidney datasets). The goodness of fit for each model was measured voxel-wise using Akaike Information Criteria (AIC). Mean AIC was calculated for each tumour volume (or contralateral normal kidney tissue). One-way ANOVAs with Greenhouse-Geisser correction and post hoc tests using the Bonferroni correction ...
Source: Magma - July 2, 2020 Category: Radiology Authors: Rogers HJ, Verhagen MV, Clark CA, Hales PW Tags: MAGMA Source Type: research

Parallel implementation of L  + S signal recovery in dynamic MRI.
Parallel implementation of L + S signal recovery in dynamic MRI. MAGMA. 2020 Jun 29;: Authors: Qazi SA, Tariq F, Ullah I, Omer H Abstract Dynamic MRI is useful to diagnose different diseases, e.g. cardiac ailments, by monitoring the structure and function of the heart and blood flow through the valves. Faster data acquisition is highly desirable in dynamic MRI, but this may lead to aliasing artifacts due to under-sampling. Advanced image reconstruction algorithms are required to obtain aliasing-free MR images from the acquired under-sampled data. One major limitation of using the advance...
Source: Magma - June 29, 2020 Category: Radiology Authors: Qazi SA, Tariq F, Ullah I, Omer H Tags: MAGMA Source Type: research

Magnetic resonance markers of bilateral neuronal metabolic dysfunction in patients with unilateral internal carotid artery occlusion.
DISCUSSION: Patients with unilateral ICA occlusion have reduced NAA/Cho ratio in the white matter of both hemispheres and have bilateral atrophy of hippocampus. The alteration of hemodynamics alone cannot explain these changes. PMID: 32594274 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - June 27, 2020 Category: Radiology Authors: Malucelli A, Skoch A, Ostry S, Tomek A, Urbanova B, Martinkovic L, Buksakowska I, Mohapl M, Netuka D, Hort J, Sroubek J, Vrana J, Moravec T, Bartos R, Sames M, Hajek M, Horinek D Tags: MAGMA Source Type: research

Accelerating the co-simulation method for the design of transmit array coils for MRI.
CONCLUSION: A fast and accurate method for tuning and decoupling of a TxArray coil can be achieved using its equivalent circuit model combined with the co-simulation method. PMID: 32594275 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - June 27, 2020 Category: Radiology Authors: Sadeghi-Tarakameh A, Kazemivalipour E, Gundogdu U, Erdogan S, Atalar E Tags: MAGMA Source Type: research

Generalization of three-dimensional golden-angle radial acquisition to reduce eddy current artifacts in bSSFP CMR imaging.
CONCLUSION: Reducing the angular step in cardio-respiratory-binned golden-angle imaging shows potential for overcoming eddy current-induced image artifacts associated with 3D golden-angle radial imaging. PMID: 32592094 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - June 26, 2020 Category: Radiology Authors: Fyrdahl A, Holst K, Caidahl K, Ugander M, Sigfridsson A Tags: MAGMA Source Type: research

Influence of injection rate in determining the development of artifacts during the acquisition of dynamic arterial phase in Gd-EOB-DTPA MRI studies.
Abstract OBJECTIVE: To assess whether different Gd-EOB-DTPA injection rates could influence the development of artifacts during the arterial phase of liver MRI studies. MATERIALS AND METHODS: All Gd-EOB-DTPA liver MRI studies performed for different clinical indications at a single tertiary referral center were retrospectively evaluated. Each examination was acquired on a 1.5 T scanner with T1 In- and Out-of-Phase, T2 with and without fat-saturation, DWI, and 3D-T1 fat-sat dynamic sequences. Patients were divided into two groups according to the injection rate (1 ml/s and 1.5 ml/s). A single ra...
Source: Magma - June 19, 2020 Category: Radiology Authors: Ippolito D, Maino C, Pecorelli A, Riva L, Querques G, Talei Franzesi C, Sironi S Tags: MAGMA Source Type: research

Correction to: Image registration in dynamic renal MRI-current status and prospects.
Rogelj P Abstract The article Image registration in dynamic renal MRI-current status and prospects, written by Frank G. Zöllner, Amira Šerifović‑Trbalić, Gordian Kabelitz, Marek Kociński, Andrzej Materka and Peter Rogelj, was originally published electronically on the publisher's internet portal on 9 October 2019 without open access.With the author(s)' decision to opt for Open Choice the copyright of the article changed on 24 April 2020 to ©. PMID: 32529447 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - June 11, 2020 Category: Radiology Authors: Zöllner FG, Šerifović-Trbalić A, Kabelitz G, Kociński M, Materka A, Rogelj P Tags: MAGMA Source Type: research

Correction to: Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper.
i A Abstract The article Phase‑contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper, written by Giulia Villa, Steffen Ringgaard, Ingo Hermann, Rebecca Noble, Paolo Brambilla, Dinah S. Khatir, Frank G. Zöllner, Susan T. Francis, Nicholas M. Selby, Andrea Remuzzi and Anna Caroli, was originally published electronically on the publisher's internet portal on 17 August 2019 without open access. PMID: 32529448 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - June 11, 2020 Category: Radiology Authors: Villa G, Ringgaard S, Hermann I, Noble R, Brambilla P, Khatir DS, Zöllner FG, Francis ST, Selby NM, Remuzzi A, Caroli A Tags: MAGMA Source Type: research

Sodium MRI of human articular cartilage of the wrist: a feasibility study on a clinical 3T MRI scanner.
CONCLUSION: We successfully determined sodium relaxation times and concentrations of the human wrist on a 3T MRI scanner. PMID: 32500389 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - June 4, 2020 Category: Radiology Authors: Müller-Lutz A, Kamp B, Nagel AM, Ljimani A, Abrar D, Schleich C, Wollschläger L, Nebelung S, Wittsack HJ Tags: MAGMA Source Type: research

SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy.
DISCUSSION: SWI and phase imaging sensitively detected intracranial calcifications in the P301L mouse model of human tauopathy. PMID: 32468149 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - May 28, 2020 Category: Radiology Authors: Ni R, Zarb Y, Kuhn GA, Müller R, Yundung Y, Nitsch RM, Kulic L, Keller A, Klohs J Tags: MAGMA Source Type: research

Assessment of brain volumes obtained from MP-RAGE and MP2RAGE images, quantified using different segmentation methods.
CONCLUSION: The results obtained advise caution when comparing brain volumes obtained by different sequences and software packages. Of note, for most brain volume measures, the MP2RAGE and MorphoBox coefficients of variation were similar to those obtained with MP-RAGE, SIENA/X or SPM, accepted tools for clinical research. PMID: 32468150 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - May 28, 2020 Category: Radiology Authors: Alonso J, Pareto D, Alberich M, Kober T, Maréchal B, Lladó X, Rovira A Tags: MAGMA Source Type: research

Effectiveness of fat suppression using a water-selective binomial-pulse excitation in chemical exchange saturation transfer (CEST) magnetic resonance imaging.
CONCLUSION: In WE-4-based CEST magnetic resonance imaging, B0 inhomogeneity is the limiting factor for fat suppression. The CEST sites at 1.0, 2.0 ppm and 3.5 ppm unavoidably suffer from lipid artifacts. However, when the ∆B0 is confined to a limited range, these CEST sites are only affected by small lipid artifacts, which may be ignorable in some cases of clinical applications. PMID: 32462557 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - May 27, 2020 Category: Radiology Authors: Zhao Y, Zu Z, Wang Z, Liu Z, Guo B, Yan X, Gochberg DF, Li J Tags: MAGMA Source Type: research

Modeling radio-frequency energy-induced heating due to the presence of transcranial electric stimulation setup at 3T.
CONCLUSION: Simulation results predicted that the electrode and gel geometries, skin electrical conductivity, and position of the temperature sensors have a significant impact on the estimated temperature rise. Therefore, these factors must be considered for reliable assessment of ΔT in subjects undergoing an MRI examination in the presence of a tES setup. PMID: 32462558 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - May 27, 2020 Category: Radiology Authors: Kozlov M, Horner M, Kainz W, Weiskopf N, Möller HE Tags: MAGMA Source Type: research

Layer-specific analysis of femorotibial cartilage t2 relaxation time based on registration of segmented double echo steady state (dess) to multi-echo-spin-echo (mese) images.
n F Abstract OBJECTIVE: To develop and validate a 3D registration approach by which double echo steady state (DESS) MR images with cartilage thickness segmentations are used to extract the cartilage transverse relaxation time (T2) from multi-echo-spin-echo (MESE) MR images, without direct segmentations for MESE. MATERIALS AND METHODS: Manual DESS segmentations of 89 healthy reference knees (healthy) and 60 knees with early radiographic osteoarthritis (early ROA) from the Osteoarthritis Initiative were registered to corresponding MESE images that had independent direct T2 segmentations. For validation purposes...
Source: Magma - May 26, 2020 Category: Radiology Authors: Fürst D, Wirth W, Chaudhari A, Eckstein F Tags: MAGMA Source Type: research

Single breath-hold saturation recovery 3D cardiac T1 mapping via compressed SENSE at 3T.
CONCLUSION: 3D SACORA acquires 3D T1 maps in 15 heart beats (heart rate, 60 bpm) at 3T. In addition to its short acquisition time, the sequence achieves good T1 estimation precision and accuracy. PMID: 32410103 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - May 14, 2020 Category: Radiology Authors: Ferreira da Silva T, Galan-Arriola C, Montesinos P, López-Martín GJ, Desco M, Fuster V, Ibáñez B, Sanchez-Gonzalez J Tags: MAGMA Source Type: research

Diffusion kurtosis imaging in liver: a preliminary reproducibility study in healthy volunteers.
Abstract OBJECTIVES: To systematically test the reproducibility of DKI technique in normal liver and report a complete set of DKI measurement data. MATERIALS AND METHODS: Thirty-two healthy volunteers were examined with liver DKI twice on the GE 3.0 T MRI scanner and reviewed by three professional experts. DKI-derived parameters fractional anisotropy of kurtosis (FAk), mean diffusivity (Md), axial diffusivity (Da), radial diffusivity (Dr), mean kurtosis (Mk), axial kurtosis (Ka), and radial kurtosis (Kr) in eight segments divided by Couinaud octagonal method were collected. Inter-class correlation coeffi...
Source: Magma - May 6, 2020 Category: Radiology Authors: Wang J, Dou W, Shi H, He X, Wang H, Ge Y, Cheng H Tags: MAGMA Source Type: research

Examining relaxivities in suspensions of nanodiamonds grafted by magnetic entities: comparison of two approaches.
CONCLUSIONS: Comparative study of two approaches for measuring relaxivity in suspensions containing DND as magnetic entities' carriers reveals complete identity of techniques in use. PMID: 32347397 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - April 28, 2020 Category: Radiology Authors: Panich AM, Shames AI, Goren SD, Yudina EB, Aleksenskii AE, Vul' AY Tags: MAGMA Source Type: research

MRI-based static and functional assessment of complex hip deformities in comparison with CT: a validation study.
CONCLUSION: Finally, it was concluded that MRI-based assessment of hip morphology and virtual ROM analysis is feasible and can be performed with good intermethod agreement in comparison to the gold standard (CT). Therefore, MRI appears to be substantially equivalent to CT for use in virtual ROM analysis and so may reasonably be used in place of CT for this purpose. PMID: 32323031 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - April 22, 2020 Category: Radiology Authors: Blum S, Franken L, Hartmann A, Thielemann F, Plodeck V, Danowski D, Kühn JP, Hoffmann RT, Günther KP, Goronzy J Tags: MAGMA Source Type: research

An MRI-compatible varus-valgus loading device for whole-knee joint functionality assessment based on compartmental compression: a proof-of-concept study.
This study aimed to design and validate an MRI-compatible pressure-controlled varus-valgus loading device that applies loading along the joint line. METHODS: Following the device's thorough validation, we demonstrated proof of concept by subjecting a structurally intact human cadaveric knee joint to serial imaging in unloaded and loaded configurations, i.e. to varus and valgus loading at 7.5 kPa (= 73.5 N), 15 kPa (= 147.1 N), and 22.5 kPa (= 220.6 N). Following clinical standard (PDw fs) and high-resolution 3D water-selective cartilage (WATSc) sequences, we performed...
Source: Magma - April 20, 2020 Category: Radiology Authors: Said O, Schock J, Krämer N, Thüring J, Hitpass L, Schad P, Kuhl C, Abrar D, Truhn D, Nebelung S Tags: MAGMA Source Type: research

Quantitative measurement of atheroma burden: reproducibility in serial studies of atherosclerotic femoral arteries.
CONCLUSION: DASH MRI is useful for quantifying atherosclerotic vessel area and volume of femoral arteries with low variability among serial repeated scans and between observers. PMID: 32297164 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - April 16, 2020 Category: Radiology Authors: Wang Y, Liu X, Haraldsson H, Zhu C, Ballweber M, Gasper W, Hatsukami T, Saloner D Tags: MAGMA Source Type: research

Acceleration of 2D-MR fingerprinting by reducing the number of echoes with increased in-plane resolution: a volunteer study.
Abstract OBJECTIVE: To compare the absolute values and repeatability of magnetic resonance fingerprinting (MRF) with 3000 and 1500 echoes/slice acquired in 41 s and 20 s (MRF3k and MRF1.5k, respectively). MATERIALS AND METHODS: MRF3k and MRF1.5k scans based on fast imaging with steady precession (FISP) were conducted using a 3 T scanner. Inter-scan agreement and intra-scan repeatability were investigated in 41 and 28 subjects, respectively. Region-of-interest (ROI) analysis was conducted on T1 values of MRF3k by two raters, and their agreement was evaluated using intraclass correlation coeffici...
Source: Magma - April 4, 2020 Category: Radiology Authors: Yokota Y, Okada T, Fushimi Y, Yamamoto A, Nakajima S, Fujimoto K, Oshima S, Koerzdoerfer G, Nittka M, Pfeuffer J, Togashi K Tags: MAGMA Source Type: research

An in vivo proton magnetic resonance spectroscopy study with optimized echo-time technique for concurrent quantification and T2 measurement targeting glutamate in the rat brain.
DISCUSSION: The results revealed that the quantification reliability of the OpQT2-Glu was comparable to that of the single short-TE MRS and its estimation reliability for the T2 relaxation time of glutamate was enhanced compared to the multiple TE MRS for T2 measurement. Despite certain limitations, the quantification and T2 estimation of glutamate can be concurrently performed within an acceptable scan time via high-field in vivo 1H MRS with the OpQT2-Glu. PMID: 32246286 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - April 3, 2020 Category: Radiology Authors: Yoo CH, Baek HM, Song KH, Woo DC, Choe BY Tags: MAGMA Source Type: research

Non-contrast coronary magnetic resonance angiography: current frontiers and future horizons.
Abstract Coronary magnetic resonance angiography (coronary MRA) is advantageous in its ability to assess coronary artery morphology and function without ionizing radiation or contrast media. However, technical limitations including reduced spatial resolution, long acquisition times, and low signal-to-noise ratios prevent it from clinical routine utilization. Nonetheless, each of these limitations can be specifically addressed by a combination of novel technologies including super-resolution imaging, compressed sensing, and deep-learning reconstruction. In this paper, we first review the current clinical use and mo...
Source: Magma - April 2, 2020 Category: Radiology Authors: Kato Y, Ambale-Venkatesh B, Kassai Y, Kasuboski L, Schuijf J, Kapoor K, Caruthers S, Lima JAC Tags: MAGMA Source Type: research

Use of multiparametric MRI to characterize uterine fibroid tissue types.
Abstract BACKGROUND: Although the biological characteristics of uterine fibroids (UF) have implications for therapy choice and effectiveness, there is limited MRI data about these characteristics. Currently, the Funaki classification and Scaled Signal Intensity (SSI) are used to predict treatment outcome but both screening-tools appear to be suboptimal. Therefore, multiparametric and quantitative MRI was studied to evaluate various biological characteristics of UF. METHODS: 87 patients with UF underwent an MRI-examination. Differences between UF tissues and myometrium were investigated using T2-mapping, Appar...
Source: Magma - March 26, 2020 Category: Radiology Authors: Verpalen IM, Anneveldt KJ, Vos PC, Edens MA, Heijman E, Nijholt IM, Dijkstra JR, Schutte JM, Franx A, Bartels LW, Moonen CTW, Boomsma MF Tags: MAGMA Source Type: research

Analysis of three-chamber view conventional and tagged cine MRI in patients with suspected hypertrophic cardiomyopathy.
Abstract OBJECTIVES: To investigate the potential value of adding a tagged three-chamber (3Ch) cine to clinical hypertrophic cardiomyopathy (HCM) magnetic resonance imaging (MRI) protocols, including to help distinguish HCM patients with regionally impaired cardiac function. METHODS: Forty-eight HCM patients, five patients with "septal knuckle" (SK), and 20 healthy volunteers underwent MRI at 1.5T; a tagged 3Ch cine was added to the protocol. Regional strain, myocardial wall thickness, and mitral valve leaflet lengths were measured in the 3Ch view. RESULTS: In HCM, we found a reduced tangential...
Source: Magma - March 9, 2020 Category: Radiology Authors: Chitiboi T, Kanski M, Tautz L, Hennemuth A, Halpern D, Sherrid M, Axel L Tags: MAGMA Source Type: research

Automated multi-atlas segmentation of gluteus maximus from Dixon and T1-weighted magnetic resonance images.
CONCLUSION: The method allows an accurate fully automated segmentation of gluteus maximus for Dixon and T1-weighted images and provides a relatively accurate volume measurement in shorter times (~ 20 min) than the current gold-standard manual segmentations (2 h). Visual inspection of the segmentation would be required when higher accuracy is needed. PMID: 32152794 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - March 9, 2020 Category: Radiology Authors: Belzunce MA, Henckel J, Fotiadou A, Di Laura A, Hart A Tags: MAGMA Source Type: research

Treatment margins in radiotherapy for liver tumors visualized as T2*-hypointense areas on SPIO-enhanced MRI at 9.4  T.
Treatment margins in radiotherapy for liver tumors visualized as T2*-hypointense areas on SPIO-enhanced MRI at 9.4 T. MAGMA. 2020 Mar 04;: Authors: Furuta T, Yamaguchi M, Minami M, Abe O, Fujii H Abstract OBJECTIVE: To investigate whether a SPIO-labeling technique could enable MR visualization of the treatment margin after X-irradiation at a single dose of 30 Gy. MATERIALS AND METHODS: Fifteen rats bearing N1-S1 hepatoma in either the left (group 1) or right (group 2) liver lobe were examined. Four hours after systemic SPIO administration, the left lobe was selectively irradiated at 30&...
Source: Magma - March 4, 2020 Category: Radiology Authors: Furuta T, Yamaguchi M, Minami M, Abe O, Fujii H Tags: MAGMA Source Type: research

Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method.
DISCUSSION: Flow measured by PC-MRI is affected by noise and turbulence. LBM can simulate turbulent flow efficiently and accurately, it has therefore the potential to improve clinical interpretation of PC-MRI. PMID: 32108906 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - February 27, 2020 Category: Radiology Authors: Fučík R, Galabov R, Pauš P, Eichler P, Klinkovský J, Straka R, Tintěra J, Chabiniok R Tags: MAGMA Source Type: research

Dynamic contrast-enhanced QSM for perfusion imaging: a systematic comparison of ΔR2*- and QSM-based contrast agent concentration time curves in blood and tissue.
DISCUSSION: Interestingly, arterial concentration time curves based on ΔR2* versus QSM data, for a standard DSC-MRI experiment, were generally very similar in shape, and the relaxivity obtained in voxels representing blood was similar to tissue relaxivity obtained in previous studies. PMID: 32078074 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - February 20, 2020 Category: Radiology Authors: Lind E, Knutsson L, Ståhlberg F, Wirestam R Tags: MAGMA Source Type: research

Contrast-free high-resolution 3D magnetization transfer imaging for simultaneous myocardial scar and cardiac vein visualization.
DISCUSSION: MTR and LGE showed agreement in infarct detection and localization in a swine model. Free-breathing 3D MTR maps are feasible in humans but high spatial variability was observed. Further clinical studies are warranted. PMID: 32078075 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - February 20, 2020 Category: Radiology Authors: López K, Neji R, Mukherjee RK, Whitaker J, Phinikaridou A, Razavi R, Prieto C, Roujol S, Botnar R Tags: MAGMA Source Type: research

Correction to: Development of a new phantom simulating extracellular space of tumor cell growth and cell edema for diffusion-weighted magnetic resonance imaging.
Abstract The original version of this article unfortunately contained a mistake. Second column of "Cell edema" should read as. PMID: 32060671 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - February 14, 2020 Category: Radiology Authors: Mikayama R, Yabuuchi H, Matsumoto R, Kobayashi K, Yamashita Y, Kimura M, Kamitani T, Sagiyama K, Yamasaki Y Tags: MAGMA Source Type: research

Correction to: Accelerated quantification of tissue sodium concentration in skeletal muscle tissue: quantitative capability of dictionary learning compressed sensing.
Abstract The original version of this article unfortunately contained a mistake. Title was incorrect. PMID: 32048100 [PubMed - as supplied by publisher] (Source: Magma)
Source: Magma - February 12, 2020 Category: Radiology Authors: Utzschneider M, Behl NGR, Lachner S, Gast LV, Maier A, Uder M, Nagel AM Tags: MAGMA Source Type: research