Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research

Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research

Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research

Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae)
The objective of this study was to evaluate the toxicity of essential oils to Diaphania hyalinata (Lepidoptera: Crambidae) and to show regions with the potential to use Cinnamomum zeylanicum, Citrus sinensis, and Syzygium aromaticum in the formulation and commercialization of insecticides to control this insect. The C. zeylanicum oil was more toxic to larvae and pupae and the S. aromaticum to eggs of D. hyalinata. Essential oils are an alternative for the management of D. hyalinata. The production of pesticides from essential oils of C. zeylanicum, C. sinensis, and S. aromaticum to control D. hyalinata has high potential i...
Source: An Acad Bras Cienc - December 21, 2023 Category: Science Authors: Isabel M DA Silva Jos é E Serrão Marinalva M Dos Santos Ricardo S DA Silva Am élia G DE Carvalho Evaldo M Pires Jos é C Zanuncio Marcus A Soares Source Type: research

csi-miR-96-5p delivered by Clonorchis sinensis extracellular vesicles promotes intrahepatic cholangiocarcinoma proliferation and migration via the ferroptosis-related PTEN/SLC7A11/GPX4 axis
Clonorchis sinensis (CS) is classified as a group 1 carcinogen and can cause intrahepatic cholangiocarcinoma (ICC). CS extracellular vesicles (CsEVs) play important roles in mediating communication between parasi... (Source: Parasites and Vectors)
Source: Parasites and Vectors - December 20, 2023 Category: Microbiology Authors: Li-Jia Wen, Ji-Gang Yin, Yong-Xin Wang, Kai Liu and Ji-Xue Zhao Tags: Research Source Type: research

Profiles of biliary microbiota in biliary obstruction patients with Clonorchis sinensis infection
ConclusionC. sinensis infection could modify the biliary microbiota, increasing the abundance and changing the phylogenetic composition of bacterial in biliary obstruction patients. This study may help deepen the understanding of the host-biliary microbiota interplay with C. sinensis infection on the background of biliary obstruction and provide new insights into understanding the pathogenesis of clonorchiasis. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - December 18, 2023 Category: Microbiology Source Type: research

Multi-omics approaches reveal the molecular mechanisms underlying the interaction between Clonorchis sinensis and mouse liver
ConclusionOur study revealed that the most severe symptoms in mice infected with C. sinensis occurred at 5 weeks post-infection. Moreover, multi-omics analysis uncovered predominant molecular events related to fibrosis changes in the liver. This study not only enhances our understanding of clonorchiasis progression but also provides valuable insights into the molecular-level interaction mechanism between C. sinensis and its host liver. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - November 24, 2023 Category: Microbiology Source Type: research

ASPSCR-1 and Sirt-5 alleviate Clonorchis liver fluke rCs NOSIP-induced oxidative stress, proliferation, and migration in cholangiocarcinoma cells
CONCLUSIONS: Our findings suggest that CsNOSIP as a component of CsESPs might promote the development and invasion of CCA and Sirt5/ ASPSCR1 as host molecules might play a novel protective role against adverse stimulus during C. sinensis infection. This work supports the idea that CsESPs induce the occurrence and progression of CCA through ROS/RNS-induced oxidative and nitrative DNA damage.PMID:37948465 | DOI:10.1371/journal.pntd.0011727 (Source: Cancer Control)
Source: Cancer Control - November 10, 2023 Category: Cancer & Oncology Authors: Meng Bian Shan Li Hanzong Zhou Lijun Bi Yong Shen Chen Tingjin Xinbing Yu Yan Huang Qingxia Xu Source Type: research

ASPSCR-1 and Sirt-5 alleviate Clonorchis liver fluke r < i > Cs < /i > NOSIP-induced oxidative stress, proliferation, and migration in cholangiocarcinoma cells
ConclusionsOur findings suggest thatCsNOSIP as a component ofCsESPs might promote the development and invasion of CCA and Sirt5/ ASPSCR1 as host molecules might play a novel protective role against adverse stimulus duringC.sinensis infection. This work supports the idea thatCsESPs induce the occurrence and progression of CCA through ROS/RNS-induced oxidative and nitrative DNA damage. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - November 10, 2023 Category: Tropical Medicine Authors: Meng Bian Source Type: research

ASPSCR-1 and Sirt-5 alleviate Clonorchis liver fluke r < i > Cs < /i > NOSIP-induced oxidative stress, proliferation, and migration in cholangiocarcinoma cells
ConclusionsOur findings suggest thatCsNOSIP as a component ofCsESPs might promote the development and invasion of CCA and Sirt5/ ASPSCR1 as host molecules might play a novel protective role against adverse stimulus duringC.sinensis infection. This work supports the idea thatCsESPs induce the occurrence and progression of CCA through ROS/RNS-induced oxidative and nitrative DNA damage. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - November 10, 2023 Category: Tropical Medicine Authors: Meng Bian Source Type: research

Clonorchis sinensis calcium-binding protein Cs16 causes acute hepatic injury possibly by reprogramming the metabolic pathway of bone marrow-derived monocytes
In this study, we report that C. sinensis calcium-binding protein Cs16 activates host immune cells and induces immunopathology in liver.MethodsImmunohistochemistry was used to detect the localization of Cs16 in C. sinensis adult worms. ELISA was used to detect the serum levels of anti-Cs16 IgG antibody in infected humans and mice. Bile duct injection model was used to figure out the role of Cs16 in vivo. RT-qPCR and ELISA were used to detect the cytokine production from Cs16-treated BMMs in vitro. Seahorse assay was used to detect the metabolic pathway of Cs16-treated BMMs in vitro.ResultCs16 localizes in the tegument and ...
Source: Frontiers in cellular and infection microbiology - October 18, 2023 Category: Microbiology Source Type: research

Spatio-temporal disparities of Clonorchis sinensis infection in animal hosts in China: a systematic review and meta-analysis
ConclusionsThere are spatio-temporal disparities in the animal infections ofC.sinensis in different areas of China. Animal infections are primarily concentrated in regions with low altitude and high precipitation. The results suggest that implementing One Health-based comprehensive measures targeting both humans and animals, especially in high epidemic areas, is essential for successful eradication ofC.sinensis in China. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - October 17, 2023 Category: Infectious Diseases Source Type: research

Parallel detection of multiple zoonotic parasites using a real-time fluorogenic loop-mediated isothermal amplification-based quadruple-sample microfluidic chip
Zoonotic parasites pose significant health risks globally. In the present study, we combined a microfluidic chip with loop-mediated isothermal amplification (on-chip LAMP) to detect five zoonotic parasites: Toxoplasma gondii, Cryptosporidium parvum, Cryptosporidium hominis, Clonorchis sinensis, and Taenia solium. This method enabled the simultaneous parallel analysis of five genetic markers from a maximum of four samples per chip. The on-chip LAMP assay was conducted in a highly automated format via the addition (by pipetting) of each sample in a single operation. The reaction was performed in volumes as low as 5 μL at ...
Source: Frontiers in Microbiology - September 26, 2023 Category: Microbiology Source Type: research

Fabrication of Nickel/Zinc Oxide Nanocomposites from Citrus sinensis Extract Prompts Apoptosis Through Impeding JAK/STAT3 Signaling in Gastric Cancer
In this study, we sought to fabricate nickel/zinc oxide nanocomposites utilizing Citrus sinensis (C. sinensis) peel extract (CS-Ni/ZnO NCs) and investigate their ability to impede the JAK/STAT3 signaling pathway in gastric cancer AGS cells. Different methods, including UV-Vis spectral analysis, FT-IR, XRD, FE-SEM, EDAX, DLS, and zeta potential, were used to characterize the fabricated CS-Ni/ZnO NCs. By measuring ROS, MMP, and apoptotic cell death using the appropriate fluorescence describing procedures, the anticancer potential of CS-Ni/ZnO NCs was examined against AGS cells. The synthesized CS-Ni/ZnO NCs displayed a rod s...
Source: Applied Biochemistry and Biotechnology - September 15, 2023 Category: Biochemistry Authors: Zhifei Li Zhongwei Sun Source Type: research

Fabrication of Nickel/Zinc Oxide Nanocomposites from Citrus sinensis Extract Prompts Apoptosis Through Impeding JAK/STAT3 Signaling in Gastric Cancer
In this study, we sought to fabricate nickel/zinc oxide nanocomposites utilizing Citrus sinensis (C. sinensis) peel extract (CS-Ni/ZnO NCs) and investigate their ability to impede the JAK/STAT3 signaling pathway in gastric cancer AGS cells. Different methods, including UV-Vis spectral analysis, FT-IR, XRD, FE-SEM, EDAX, DLS, and zeta potential, were used to characterize the fabricated CS-Ni/ZnO NCs. By measuring ROS, MMP, and apoptotic cell death using the appropriate fluorescence describing procedures, the anticancer potential of CS-Ni/ZnO NCs was examined against AGS cells. The synthesized CS-Ni/ZnO NCs displayed a rod s...
Source: Applied Biochemistry and Biotechnology - September 15, 2023 Category: Biochemistry Authors: Zhifei Li Zhongwei Sun Source Type: research