Exploration of the Amino Acid Metabolic Profiling and Pathway in Clonorchis sinensis –Infected Rats Revealed by the Targeted Metabolomic Analysis
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - April 4, 2024 Category: Infectious Diseases Authors: Jie Wan Jian Ding Xiaoli Zhang Xinyi Hu Rui Chen Su Han Source Type: research

The crosstalk between cholangiocytes and hepatic stellate cells promotes the progression of epithelial-mesenchymal transition and periductal fibrosis during Clonorchis sinensis infection
Clonorchis sinensis infection is one of the risk factors that provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis and even cholangiocarcinoma (CCA). Disrupted or aberrant intercellular comm... (Source: Parasites and Vectors)
Source: Parasites and Vectors - March 22, 2024 Category: Microbiology Authors: Junyeong Yi, Ji Hoon Jeong, Jihee Won, Seok Chung and Jhang Ho Pak Tags: Research Source Type: research

Genes, Vol. 15, Pages 380: First Record of Comparative Plastid Genome Analysis and Phylogenetic Relationships among Corylopsis Siebold & amp; Zucc. (Hamamelidaceae)
Genes, Vol. 15, Pages 380: First Record of Comparative Plastid Genome Analysis and Phylogenetic Relationships among Corylopsis Siebold & Zucc. (Hamamelidaceae) Genes doi: 10.3390/genes15030380 Authors: Tae-Hee Kim Young-Ho Ha Hiroaki Setoguchi Kyung Choi Sang-Chul Kim Hyuk-Jin Kim Corylopsis Siebold & Zucc. (Hamamelidaceae) is widely used as a horticultural plant and comprises approximately 25 species in East Asia. Molecular research is essential to distinguish Corylopsis species, which are morphologically similar. Molecular research has been conducted using a small number of genes but...
Source: Genes - March 20, 2024 Category: Genetics & Stem Cells Authors: Tae-Hee Kim Young-Ho Ha Hiroaki Setoguchi Kyung Choi Sang-Chul Kim Hyuk-Jin Kim Tags: Article Source Type: research

Expression of Concern: Molecular Characterization of Severin from < i > Clonorchis sinensis < /i > Excretory/Secretory Products and Its Potential Anti-apoptotic Role in Hepatocarcinoma PLC Cells
by The PLOS Neglected Tropical Diseases Editors (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 19, 2024 Category: Tropical Medicine Authors: The PLOS Neglected Tropical Diseases Editors Source Type: research

FASN-mediated fatty acid biosynthesis remodels immune environment in Clonorchis sinensis infection-related intrahepatic cholangiocarcinoma
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer with high lethality. Clonorchis sinensis (C. sinensis) infection is an important risk factor for ICC. Here we investigated the clinical impact and underlying molecular characteristics of C. sinensis-infected ICC. (Source: Journal of Hepatology)
Source: Journal of Hepatology - March 18, 2024 Category: Gastroenterology Authors: Lixia Xu, Ying Zhang, Zhilong Lin, Xinlang Deng, Xiaoxue Ren, Mingle Huang, Shangru Li, Qianying Zhou, Fei Fang, Qingxia Yang, Gaomin Zheng, Zebin Chen, Zhongdao Wu, Xi Sun, Jie Lin, Jingxian Shen, Jianping Guo, Xiaoxing Li, Tianchen Xue, Jing Tan, Xiaoxu Tags: Research Article Source Type: research

Natural variables separate the endemic areas of Clonorchis sinensis and Opisthorchis viverrini along a continuous, straight zone in Southeast Asia
ConclusionsOur findings highlight the critical role of specific climatic and environmental factors in influencing the geographical distribution ofC. sinensis andO. viverrini. This spatial delineation offers valuable insights for integrated surveillance and control strategies, particularly in regions with sympatric transmission. The results underscore the need for tailored interventions, considering regional epidemiological variations. Future collaborations integrating eco-epidemiology, molecular epidemiology, and parasitology are essential to further elucidate the complex interplay of liver fluke distributions in Asia. (So...
Source: Infectious Diseases of Poverty - March 12, 2024 Category: Infectious Diseases Source Type: research

Comprehensive investigation of differentially expressed ncRNAs, mRNAs, and their ceRNA networks in the regulation of shell color formation in clam, Cyclina sinensis
This study aimed to address this knowledge gap by systematically identifying ncRNAs in the mantles of C. sinensis with purple and white shells. Through our analysis, we identified a differential expression of 1244 mRNAs, 196 lncRNAs, 49 circRNAs, and 23 miRNAs between purple- and white-shell clams. Functional enrichment analysis revealed the involvement of these differentially expressed ncRNAs in biomineralization and pigmentation processes. To gain further insights into the regulatory mechanisms underlying shell color formation, we established competitive endogenous RNA (ceRNA) networks. These networks allowed us to ident...
Source: Gene - March 7, 2024 Category: Genetics & Stem Cells Authors: Yuyan Sun Xuxiao Liu Xin Shan Yiwo Wang Chongyu Zhong Chaofa Lu Bin Guan Shun Yao Yujia Huo Runkai Sun Min Wei Zhiguo Dong Source Type: research

Comprehensive investigation of differentially expressed ncRNAs, mRNAs, and their ceRNA networks in the regulation of shell color formation in clam, Cyclina sinensis
This study aimed to address this knowledge gap by systematically identifying ncRNAs in the mantles of C. sinensis with purple and white shells. Through our analysis, we identified a differential expression of 1244 mRNAs, 196 lncRNAs, 49 circRNAs, and 23 miRNAs between purple- and white-shell clams. Functional enrichment analysis revealed the involvement of these differentially expressed ncRNAs in biomineralization and pigmentation processes. To gain further insights into the regulatory mechanisms underlying shell color formation, we established competitive endogenous RNA (ceRNA) networks. These networks allowed us to ident...
Source: Gene - March 7, 2024 Category: Genetics & Stem Cells Authors: Yuyan Sun Xuxiao Liu Xin Shan Yiwo Wang Chongyu Zhong Chaofa Lu Bin Guan Shun Yao Yujia Huo Runkai Sun Min Wei Zhiguo Dong Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research

Comparative Phylogenetic Analysis of Ancient Korean Tea "Hadong Cheon-Nyeon Cha ( < em > Camellia sinensis < /em > var. < em > sinensis < /em > )" Using Complete Chloroplast Genome Sequences
This study determined seven Camellia sinensis var. sinenesis, including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes. Further, differences in SNPs and InDels were detected across the seven chloroplast genomes through variance analysis. Principal component and phylogenetic analysis suggested that regional constraints, rather than functional constraints, strongly affected the sequence evolution of the cp geno...
Source: Current Issues in Molecular Biology - February 23, 2024 Category: Molecular Biology Authors: Doobo Shim Seung Ho Jeon Jong Cheol Kim Dong-Kyung Yoon Source Type: research