The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent and Young Adult Cancers Version 6
Indian Pediatr. 2024 Apr 15;61(4):380-382.NO ABSTRACTPMID:38597104 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 10, 2024 Category: Pediatrics Authors: Maya Prasad Smita Bhatia Ramandeep Singh Arora Source Type: research
The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent and Young Adult Cancers Version 6
Indian Pediatr. 2024 Apr 15;61(4):380-382.NO ABSTRACTPMID:38597104 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 10, 2024 Category: Pediatrics Authors: Maya Prasad Smita Bhatia Ramandeep Singh Arora Source Type: research
The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent and Young Adult Cancers Version 6
Indian Pediatr. 2024 Apr 15;61(4):380-382.NO ABSTRACTPMID:38597104 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 10, 2024 Category: Pediatrics Authors: Maya Prasad Smita Bhatia Ramandeep Singh Arora Source Type: research
GSE254783 Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment [HiChIP]
Contributors : Kashi Raj Bhattarai ; Robert J Mobley ; Kelly R Barnett ; Daniel C Ferguson ; Jonathan D Diedrich ; Brennan P Bergeron ; Satoshi Yoshimura ; Wenjian Yang ; Kristine R Crews ; Elias Jabbour ; Christopher S Manring ; Elisabeth Paietta ; Steven M Kornblau ; Wendy Stock ; Hiroto Inaba ; Sima Jeha ; Ching-Hon Pui ; Cheng Cheng ; Mary V Relling ; William E Evans ; Jun J Yang ; Daniel SavicSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Homo sapiensAlthough acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer, there is limited understa...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Other Homo sapiens Source Type: research
GSE225263 Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment [MPRA]
Contributors : Kashi Raj Bhattarai ; Robert J Mobley ; Kelly R Barnett ; Daniel C Ferguson ; Jonathan D Diedrich ; Brennan P Bergeron ; Wenjian Yang ; Kristine R Crews ; Elias Jabbour ; Christopher S Manring ; Elisabeth Paietta ; Steven M Kornblau ; Wendy Stock ; Hiroto Inaba ; Sima Jeha ; Ching-Hon Pui ; Cheng Cheng ; Mary V Relling ; William E Evans ; Jun J Yang ; Daniel SavicSeries Type : OtherOrganism : Homo sapiens ; synthetic constructAlthough acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer, there is limited understanding of the contribution of inherited genetic variation on inter-...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Other Homo sapiens synthetic construct Source Type: research
GSE224956 Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment [ChIP-Seq]
Contributors : Kashi R Bhattarai ; Robert J Mobley ; Kelly R Barnett ; Daniel C Ferguson ; Jonathan D Diedrich ; Brennan P Bergeron ; Wenjian Yang ; Kristine R Crews ; Elias Jabbour ; Christopher S Manring ; Elisabeth Paietta ; Steven M Kornblau ; Wendy Stock ; Hiroto Inaba ; Sima Jeha ; Ching-Hon Pui ; Cheng Cheng ; Mary V Relling ; William E Evans ; Jun J Yang ; Daniel SavicSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensAlthough acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer, there is limited understanding of the contribution of inh...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research
GSE224530 Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment [ATAC-seq]
Contributors : Kashi R Bhattarai ; Robert J Mobley ; Kelly R Barnett ; Daniel C Ferguson ; Jonathan D Diedrich ; Brennan P Bergeron ; Wenjian Yang ; Kristine R Crews ; Elias Jabbour ; Christopher S Manring ; Elisabeth Paietta ; Steven M Kornblau ; Wendy Stock ; Hiroto Inaba ; Sima Jeha ; Ching-Hon Pui ; Cheng Cheng ; Mary V Relling ; William E Evans ; Jun J Yang ; Daniel SavicSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensAlthough acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer, there is limited understanding of the contribution of inh...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research
GSE224203 Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment [HiC]
Contributors : Kashi R Bhattarai ; Robert J Mobley ; Kelly R Barnett ; Daniel C Ferguson ; Jonathan D Diedrich ; Brennan P Bergeron ; Wenjian Yang ; Kristine R Crews ; Elias Jabbour ; Christopher S Manring ; Elisabeth Paietta ; Steven M Kornblau ; Wendy Stock ; Hiroto Inaba ; Sima Jeha ; Ching-Hon Pui ; Cheng Cheng ; Mary V Relling ; William E Evans ; Jun J Yang ; Daniel SavicSeries Type : OtherOrganism : Homo sapiensAlthough acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer, there is limited understanding of the contribution of inherited genetic variation on inter-individual differences in...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research
GSE224085 Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment [CUT & RUN]
Contributors : Kashi R Bhattarai ; Robert J Mobley ; Kelly R Barnett ; Daniel C Ferguson ; Jonathan D Diedrich ; Brennan P Bergeron ; Wenjian Yang ; Kristine R Crews ; Elias Jabbour ; Christopher S Manring ; Elisabeth Paietta ; Steven M Kornblau ; Wendy Stock ; Hiroto Inaba ; Sima Jeha ; Ching-Hon Pui ; Cheng Cheng ; Mary V Relling ; William E Evans ; Jun J Yang ; Daniel SavicSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensAlthough acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer, there is limited understanding of the contribution of inh...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research
ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer
DiscussionECLIM-SEHOP platform has remarkably improved the availability and accessibility of international academic clinical trials and has facilitated the centralization of resources in childhood cancer treatment. Despite the progressive improvement on clinical trial set-up metrics, timings should still be improved. The program has contributed to leveling survival rates in Spain with those of other European countries that presented major differences in the past. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - April 10, 2024 Category: Cancer & Oncology Source Type: research
Endogenous S100P-mediated autophagy regulates the chemosensitivity of leukemia cells through the p53/AMPK/mTOR pathway
Am J Cancer Res. 2024 Mar 15;14(3):1121-1138. doi: 10.62347/NWXE8730. eCollection 2024.ABSTRACTAutophagy, a highly regulated lysosome-dependent catabolic pathway, has garnered increasing attention because of its role in leukemia resistance. Among the S100 family of small calcium-binding proteins, S100P is differentially expressed in various tumor cell lines, thereby influencing tumor occurrence, invasion, metastasis, and drug resistance. However, the relationship between S100P and autophagy in determining chemosensitivity in leukemia cells remains unexplored. Our investigation revealed a negative correlation between S100P ...
Source: Cell Research - April 9, 2024 Category: Cytology Authors: Min Peng Fanghua Ye Chenying Fan Jiajia Dong Wenwen Chai Wenjun Deng Hui Zhang Liangchun Yang Source Type: research
Assessment of the FRET-based Teen sensor to monitor ERK activation changes preceding morphological defects in a RASopathy zebrafish model and phenotypic rescue by MEK inhibitor
CONCLUSION: This work proves the usefulness of FRET imaging protocols on both live and fixed Teen ERK reporter fish to readily monitor and quantify pharmacologically- and genetically-induced ERK activity modulations in early embryos, representing a useful tool in pre-clinical applications targeting RAS-MAPK signaling.PMID:38594640 | DOI:10.1186/s10020-024-00807-w (Source: Molecular Medicine)
Source: Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Giulia Fasano Stefania Petrini Valeria Bonavolont à Graziamaria Paradisi Catia Pedalino Marco Tartaglia Antonella Lauri Source Type: research
Radiation doses received by major organs at risk in children and young adolescents treated for cancer with external beam radiation therapy: a large-scale study from 12 European countries
CONCLUSION: The detailed dose estimates provide very useful information for former patients or clinicians who have only limited knowledge about radiation therapy protocols or techniques, but who know the type and site of childhood cancer, gender, age and year of treatment. This will allow better prediction of the long-term risk of iatrogenic events and better referral to long-term follow-up clinics.PMID:38582233 | DOI:10.1016/j.ijrobp.2024.03.032 (Source: Health Physics)
Source: Health Physics - April 6, 2024 Category: Physics Authors: Ibrahima Diallo Rodrigue S Allodji Cristina Veres St éphanie Bolle Damien Llanas Safaa Ezzouhri Wael Zrafi Ghazi Debiche Vincent Souchard Romain Fauchery Nadia Haddy Neige Journy Charlotte Demoor-Goldschmidt David L Winter Lars Hjorth Thomas Wiebe Riccar Source Type: research
Radiation doses received by major organs at risk in children and young adolescents treated for cancer with external beam radiation therapy: a large-scale study from 12 European countries
CONCLUSION: The detailed dose estimates provide very useful information for former patients or clinicians who have only limited knowledge about radiation therapy protocols or techniques, but who know the type and site of childhood cancer, gender, age and year of treatment. This will allow better prediction of the long-term risk of iatrogenic events and better referral to long-term follow-up clinics.PMID:38582233 | DOI:10.1016/j.ijrobp.2024.03.032 (Source: Health Physics)
Source: Health Physics - April 6, 2024 Category: Physics Authors: Ibrahima Diallo Rodrigue S Allodji Cristina Veres St éphanie Bolle Damien Llanas Safaa Ezzouhri Wael Zrafi Ghazi Debiche Vincent Souchard Romain Fauchery Nadia Haddy Neige Journy Charlotte Demoor-Goldschmidt David L Winter Lars Hjorth Thomas Wiebe Riccar Source Type: research
Ataxia telangiectasia: a rare case report from Nepal
CONCLUSION: A-T is a complex disorder with no cure. Genetic counseling for parents is vital. Its poor prognosis due to infection susceptibility and cancer risk necessitates supportive care. Comprehensive management, including genetic counseling and careful surveillance, is imperative.PMID:38576962 | PMC:PMC10990361 | DOI:10.1097/MS9.0000000000001831 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Apil Upreti Prince Mandal Amit Upreti Srijana Sapkota Sristi Acharya Avash Yogi Bikash Gauchan Suman Bhattarai Lekhjung Thapa Source Type: research
