Circulating tumor cells help differentiate benign ovarian lesions from cancer before surgery: A literature review and proof of concept study using flow cytometry with fluorescence imaging
Oncol Lett. 2024 Mar 26;27(5):234. doi: 10.3892/ol.2024.14367. eCollection 2024 May.ABSTRACTCurrent tools are insufficient for distinguishing patients with ovarian cancer from those with benign ovarian lesions before extensive surgery. The present study utilized a readily accessible platform employing a negative selection strategy, followed by flow cytometry, to enumerate circulating tumor cells (CTCs) in patients with ovarian cancer. These counts were compared with those from patients with benign ovarian lesions. CTC counts at baseline, before and after anticancer therapy, and across various clinical scenarios involving o...
Source: Oncology Letters - April 10, 2024 Category: Cancer & Oncology Authors: Yung-Chia Kuo Chi-Hsi Chuang Hsuan-Chih Kuo Cheng-Tao Lin Angel Chao Huei-Jean Huang Hung-Ming Wang Jason Chia-Hsun Hsieh Hung-Hsueh Chou Source Type: research
Pharmacological interventions to improve sleep in people with Alzheimer's disease: a meta-analysis of randomized controlled trials
CONCLUSION: Although melatonin was the most investigated intervention, the evidence for its efficacy is inconclusive. On the other hand, trazodone and orexin receptor antagonists showed promising results; however, more RCTs are needed for definite answers.PMID:38597219 | DOI:10.1080/14737175.2024.2341004 (Source: Expert Review of Neurotherapeutics)
Source: Expert Review of Neurotherapeutics - April 10, 2024 Category: Neurology Authors: Amy Bedward Jasmine Kaur Sadiyah Seedat Holly Donohue Chia Siang Kow Muhammad Kamran Rasheed Amaan Javed Syed Shahzad Hasan Source Type: research
Pharmacological interventions to improve sleep in people with Alzheimer's disease: a meta-analysis of randomized controlled trials
CONCLUSION: Although melatonin was the most investigated intervention, the evidence for its efficacy is inconclusive. On the other hand, trazodone and orexin receptor antagonists showed promising results; however, more RCTs are needed for definite answers.PMID:38597219 | DOI:10.1080/14737175.2024.2341004 (Source: Expert Review of Neurotherapeutics)
Source: Expert Review of Neurotherapeutics - April 10, 2024 Category: Neurology Authors: Amy Bedward Jasmine Kaur Sadiyah Seedat Holly Donohue Chia Siang Kow Muhammad Kamran Rasheed Amaan Javed Syed Shahzad Hasan Source Type: research
