Modulation of secretory factors by lipofundin contributes to its anti ‑neuroinflammatory effects
Exp Ther Med. 2024 Feb 27;27(4):169. doi: 10.3892/etm.2024.12456. eCollection 2024 Apr.ABSTRACTAs the global population ages, the prevalence of neuroinflammatory diseases such as Alzheimer's disease, Parkinson's disease and stroke continues to increase. Therefore, it is necessary to develop preventive and therapeutic methods against neuroinflammatory diseases. Lipofundin is a lipid emulsion commonly used in clinical anesthetic solvents and nutritional supplements. Lipid emulsions have been shown to possess anti-inflammatory properties. However, the potential beneficial effect of lipofundin against neuroinflammation require...
Source: Experimental and Therapeutic Medicine - March 13, 2024 Category: General Medicine Authors: Ming-Shan Chen Chia-Lin Hu Shin-Kuang Jiang Zhi-Yong Chong Jui-Chieh Chen Source Type: research
Efficacy of Definitive Radiotherapy for Patients with Clinical Stage IIIB or IIIC Lung Adenocarcinoma and Epidermal Growth Factor Receptor (EGFR) Mutations Treated Using First- or Second-Generation EGFR Tyrosine Kinase Inhibitors
CONCLUSION: The addition of definitive RT to first- or second-generation EGFR TKI treatment does not significantly improve OS of patients with EGFR-mutated stage IIIB or IIIC lung adenocarcinoma. NCT03521154NCT05167851.PMID:38476120 | PMC:PMC10932622 | DOI:10.1155/2024/8889536 (Source: Respiratory Care)
Source: Respiratory Care - March 13, 2024 Category: Respiratory Medicine Authors: Chih-Yen Tu Te-Chun Hsia Ying-Chun Lin Ji-An Liang Chia-Chin Li Chun-Ru Chien Source Type: research
Association of postpartum depression with child growth and developmental outcomes: a community-based study
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-107. Online ahead of print.NO ABSTRACTPMID:38478737 | DOI:10.4103/singaporemedj.SMJ-2023-107 (Source: Singapore Medical Journal)
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Moira Suyin Chia Nur Adila Binte Ahmad Hatib Elaine Chu Shan Chew Shu-Ling Chong Rehena Sultana Ade Xin Ning Tan Xiaoxuan Guo David Chee Chin Ng Padmini Sita Yeleswarapu Pratibha Keshav Agarwal Helen Yu Chen Yoke Hwee Chan Source Type: research
HER2-low breast cancers: challenges in the interpretation of immunohistochemistry
Singapore Med J. 2024 Mar 13. doi: 10.4103/singaporemedj.SMJ-2023-037. Online ahead of print.ABSTRACTOverexpression of human epidermal growth factor receptor 2 (HER2) protein in breast cancers carries significant prognostic and therapeutic implications. Anti-HER2 blockade has shown to be a useful adjunct to surgery in treating HER2-positive tumours. Up till today, the HER2 immunohistochemistry (IHC) and in situ hybridisation (ISH) scoring algorithms are geared towards identifying HER2-positive cases. A recently published Phase III clinical trial (DESTINY-Breast04) has demonstrated that an antibody-drug conjugate (trastuzum...
Source: Singapore Medical Journal - March 13, 2024 Category: General Medicine Authors: Noel Chia Mihir Ananta Gudi Emad Rakha Puay Hoon Tan Source Type: research
Modulation of secretory factors by lipofundin contributes to its anti ‑neuroinflammatory effects
Exp Ther Med. 2024 Feb 27;27(4):169. doi: 10.3892/etm.2024.12456. eCollection 2024 Apr.ABSTRACTAs the global population ages, the prevalence of neuroinflammatory diseases such as Alzheimer's disease, Parkinson's disease and stroke continues to increase. Therefore, it is necessary to develop preventive and therapeutic methods against neuroinflammatory diseases. Lipofundin is a lipid emulsion commonly used in clinical anesthetic solvents and nutritional supplements. Lipid emulsions have been shown to possess anti-inflammatory properties. However, the potential beneficial effect of lipofundin against neuroinflammation require...
Source: Experimental and Therapeutic Medicine - March 13, 2024 Category: General Medicine Authors: Ming-Shan Chen Chia-Lin Hu Shin-Kuang Jiang Zhi-Yong Chong Jui-Chieh Chen Source Type: research
