Sterically Hindered Tetradentate [Pt(O^N^C^N)] Emitters with Radiative Decay Rates up to 5.3 × 105 s−1 for Phosphorescent Organic Light‐Emitting Diodes with LT95 Lifetime over 9200 h at 1000 cd m−2 (Small 12/2024)
Organic Light-Emitting DiodesIn article number2307393, Gang Cheng, Lei Dai, Chi-Ming Che, and co-workers realized operationally stable and high-performance vapor-deposited green phosphorescent organic light-emitting diodes with sterically hindered tetradentate [Pt(O^N^C^N)] emitters. The corresponding Pt-based devices display EL spectra with full width at half maximum down to 36 nm, high external quantum efficiency and CE of up to 27.6% and 98.7 cd A−1, respectively, alongside practical device lifetimes (LT95) of up to 9270 hours at an initial luminance of 1000 cd m−2. (Source: Small)
Source: Small - March 23, 2024 Category: Nanotechnology Authors: Tsz ‐Lung Lam, Huiyang Li, Kaixin Tan, Ziyong Chen, Yu‐Kan Tang, Jun Yang, Gang Cheng, Lei Dai, Chi‐Ming Che Tags: Inside Front Cover Source Type: research

Preterm birth increases cerebral palsy hazards in children of mothers with chronic hypertension in pregnancy
Children of mothers with chronic-hypertension in pregnancy have high rates of preterm-birth ( (Source: Pediatrics and Neonatology)
Source: Pediatrics and Neonatology - March 22, 2024 Category: Perinatology & Neonatology Authors: Yi-Chien Huang, Hung-Chih Lin, Yu-Tzu Chang, Ming-Luen Tsai, Yu-Chia Chang, Lan-Wan Wang Source Type: research

Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function
J Cell Mol Med. 2024 Apr;28(7):e18243. doi: 10.1111/jcmm.18243.ABSTRACTHumans lacking heme oxygenase 1 (HMOX1) display growth retardation, haemolytic anaemia, and vulnerability to stress; however, cardiac function remains unclear. We aimed to explore the cardiac function of zebrafish lacking hmox1a at baseline and in response to stress. We generated zebrafish hmox1a mutants using CRISPR/Cas9 genome editing technology. Deletion of hmox1a increases cardiac output and further induces hypertrophy in adults. Adults lacking hmox1a develop myocardial interstitial fibrosis, restrain cardiomyocyte proliferation and downregulate ren...
Source: J Cell Mol Med - March 21, 2024 Category: Molecular Biology Authors: Hong Wang Juuso Siren Sanni Perttunen Katariina Immonen Yu-Chia Chen Suneeta Narumanchi Riikka Kosonen Jere Paavola Mika Laine Ilkka Tikkanen P äivi Lakkisto Source Type: research

Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function
J Cell Mol Med. 2024 Apr;28(7):e18243. doi: 10.1111/jcmm.18243.ABSTRACTHumans lacking heme oxygenase 1 (HMOX1) display growth retardation, haemolytic anaemia, and vulnerability to stress; however, cardiac function remains unclear. We aimed to explore the cardiac function of zebrafish lacking hmox1a at baseline and in response to stress. We generated zebrafish hmox1a mutants using CRISPR/Cas9 genome editing technology. Deletion of hmox1a increases cardiac output and further induces hypertrophy in adults. Adults lacking hmox1a develop myocardial interstitial fibrosis, restrain cardiomyocyte proliferation and downregulate ren...
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Hong Wang Juuso Siren Sanni Perttunen Katariina Immonen Yu-Chia Chen Suneeta Narumanchi Riikka Kosonen Jere Paavola Mika Laine Ilkka Tikkanen P äivi Lakkisto Source Type: research

Hemorrhage risk prediction after computed tomography-guided lung biopsy: Clinical parameters and quantitative pulmonary vascular analysis
CONCLUSIONS: Higher-grade pulmonary hemorrhage may occur after CT-guided lung biopsy. Lesion depth, vessel density, and BV5 are independent risk factors for higher-grade pulmonary hemorrhage. Nomograms integrating clinical parameters and radiographic pulmonary vasculature measures offer enhanced capability for assessing hemorrhage risk following CT-guided lung biopsy, thereby facilitating improved patient clinical care.PMID:38514373 | DOI:10.1016/j.jfma.2024.03.011 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 21, 2024 Category: General Medicine Authors: Keng-Chian Lin Wei-Chun Ko Yu-Dian Tsai Chia-Yun Chang Yung-Hsuan Yang Yu-Sen Huang Yeun-Chung Chang Source Type: research

Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function
J Cell Mol Med. 2024 Apr;28(7):e18243. doi: 10.1111/jcmm.18243.ABSTRACTHumans lacking heme oxygenase 1 (HMOX1) display growth retardation, haemolytic anaemia, and vulnerability to stress; however, cardiac function remains unclear. We aimed to explore the cardiac function of zebrafish lacking hmox1a at baseline and in response to stress. We generated zebrafish hmox1a mutants using CRISPR/Cas9 genome editing technology. Deletion of hmox1a increases cardiac output and further induces hypertrophy in adults. Adults lacking hmox1a develop myocardial interstitial fibrosis, restrain cardiomyocyte proliferation and downregulate ren...
Source: J Cell Mol Med - March 21, 2024 Category: Molecular Biology Authors: Hong Wang Juuso Siren Sanni Perttunen Katariina Immonen Yu-Chia Chen Suneeta Narumanchi Riikka Kosonen Jere Paavola Mika Laine Ilkka Tikkanen P äivi Lakkisto Source Type: research

Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function
J Cell Mol Med. 2024 Apr;28(7):e18243. doi: 10.1111/jcmm.18243.ABSTRACTHumans lacking heme oxygenase 1 (HMOX1) display growth retardation, haemolytic anaemia, and vulnerability to stress; however, cardiac function remains unclear. We aimed to explore the cardiac function of zebrafish lacking hmox1a at baseline and in response to stress. We generated zebrafish hmox1a mutants using CRISPR/Cas9 genome editing technology. Deletion of hmox1a increases cardiac output and further induces hypertrophy in adults. Adults lacking hmox1a develop myocardial interstitial fibrosis, restrain cardiomyocyte proliferation and downregulate ren...
Source: Molecular Medicine - March 21, 2024 Category: Molecular Biology Authors: Hong Wang Juuso Siren Sanni Perttunen Katariina Immonen Yu-Chia Chen Suneeta Narumanchi Riikka Kosonen Jere Paavola Mika Laine Ilkka Tikkanen P äivi Lakkisto Source Type: research

Hemorrhage risk prediction after computed tomography-guided lung biopsy: Clinical parameters and quantitative pulmonary vascular analysis
CONCLUSIONS: Higher-grade pulmonary hemorrhage may occur after CT-guided lung biopsy. Lesion depth, vessel density, and BV5 are independent risk factors for higher-grade pulmonary hemorrhage. Nomograms integrating clinical parameters and radiographic pulmonary vasculature measures offer enhanced capability for assessing hemorrhage risk following CT-guided lung biopsy, thereby facilitating improved patient clinical care.PMID:38514373 | DOI:10.1016/j.jfma.2024.03.011 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - March 21, 2024 Category: General Medicine Authors: Keng-Chian Lin Wei-Chun Ko Yu-Dian Tsai Chia-Yun Chang Yung-Hsuan Yang Yu-Sen Huang Yeun-Chung Chang Source Type: research

Design and simulation of light field patterns for angular color variation reduction in micro-LED and mini-LED RGB arrays
We propose a methodology to mitigate angular color variation in full-color micron-scale LED arrays. By simulating light field distribution ... (Source: Applied Optics)
Source: Applied Optics - March 21, 2024 Category: Physics Authors: Shu-Mei Yang Chia-Hsin Chao Yu-Sheng Chen Ming-Hsien Wu Yen-Hsiang Fang Chien-Chung Lin Source Type: research

Assessing the diversity and determinants of health ‐related quality of life measures in patients with acute heart failure
ConclusionsThis study illuminates the variance in HR-QoL measurement tools for Taiwanese HFrEF patients. Using a range of these tools is beneficial in unveiling diverse determinants and approaching comprehensive patient-centred care. However, for a more precise HR-QoL assessment in Taiwanese HFrEF patients, recalibrating the EQ-5D-derived utility scores might be necessary, emphasizing the importance of patient-specific considerations within the HF-PAC programme. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 21, 2024 Category: Cardiology Authors: Dhrumil Patil, Hsin ‐Ju Tang, Fang‐Hsiu Kuo, Han Siong Toh, I‐Ning Yang, Wei‐Ting Chang, Mei‐Chuan Lee, Kai‐Ning Chung, Chi‐Ya Huang, Wan‐Hsuan Hsu, Ting‐Chia Chang, Jhih‐Yuan Shih, Chia‐Te Liao Tags: Original Article Source Type: research

Cancers, Vol. 16, Pages 1233: Enhancing Whole-Brain Magnetic Field Homogeneity for 3D-Magnetic Resonance Spectroscopic Imaging with a Novel Unified Coil: A Preliminary Study
Li Hsin-Jung Yang Hui Han The spectral quality of magnetic resonance spectroscopic imaging (MRSI) can be affected by strong magnetic field inhomogeneities, posing a challenge for 3D-MRSI’s widespread clinical use with standard scanner-equipped 2nd-order shim coils. To overcome this, we designed an empirical unified shim–RF head coil (32-ch RF receive and 51-ch shim) for 3D-MRSI improvement. We compared its shimming performance and 3D-MRSI brain coverages against the standard scanner shim (2nd-order spherical harmonic (SH) shim coils) and integrated parallel reception, excitation, and shi...
Source: Cancers - March 21, 2024 Category: Cancer & Oncology Authors: Archana Vadiraj Malagi Xinqi Li Na Zhang Yucen Liu Yuheng Huang Fardad Michael Serry Ziyang Long Chia-Chi Yang Yujie Shan Yubin Cai Jeremy Zepeda Nader Binesh Debiao Li Hsin-Jung Yang Hui Han Tags: Article Source Type: research