Reviewing the all-in-pod heart health segment
BY ANISH KOKA The All-in podcast is a fairly popular show that features successful silicon valley investors commenting about everything worth commenting on from politics to health. The group has good chemistry and interesting insights that breaks the mold of the usual tribal politics that controls legacy media analysis of current events. Last week, the podcast touched on a topic I spend a fair amount of time on: Cardiology. Brad Gerstner, who is actually a guest host for this particular episode starts off by referencing something called Heartflow to evaluate the heart that has been recommended by one of the o...
Source: The Health Care Blog - July 20, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice All-in Podcast Anish Koka Brad Gerstner cardiology Source Type: blogs

Alpha-Beta-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In conclusion, the advent of alpha-beta-blockers has marked a significant advancement in cardiovascular treatment. These medications, combining the properties of both alpha and beta blockers, have demonstrated superiority in managing various cardiovascular conditions. They offer the potential for enhanced blood pressure control, cardiovascular protection, and versatility in the management of several cardiovascular conditions. The choice of using alpha-beta-blockers, however, must be tailored to the individual patient. Considerations such as past medical records, present health conditions, concurrent ...
Source: The EMT Spot - July 20, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Pulmonary Arterial Hypertension: Unraveling Its Impact On Heart And Lungs
Conclusion Navigating the complexities of Pulmonary Arterial Hypertension (PAH) might seem daunting. However, with the right knowledge and proactive approach, it’s possible to manage the condition and maintain a good quality of life. PAH, a unique type of high blood pressure affecting the arteries in the lungs, can put extra strain on the heart. Over time, this can lead to heart failure. The condition’s root cause may vary, from genetic factors to other health issues like heart defects, liver disease, or autoimmune diseases. Remember, sometimes the cause remains unknown, resulting in idiopathic pulmonary ...
Source: The EMT Spot - July 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

How Alcohol Affects Blood Pressure: A Detailed Insight
Conclusion In this guide, we’ve explored the complex relationship between alcohol and blood pressure. We’ve seen that alcohol, whether consumed moderately, heavily, or in a binge pattern, can impact blood pressure. We also delved into the biological mechanisms at play, the role of various drinking patterns, and the sobering revelations of recent research. While the pleasure of a drink might be fleeting, its effects on our body, particularly on our blood pressure, can be long-lasting. The key takeaway? Moderation. Even a small reduction in alcohol intake can have significant health benefits, partic...
Source: The EMT Spot - July 18, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Alpha-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion To summarize, the treatment of hypertension is a critical aspect of healthcare due to its significant impact on cardiovascular health. While natural supplements and lifestyle modifications are important for overall well-being, the use of chemical drugs in managing hypertension remains necessary. Chemical drugs for hypertension have undergone extensive research and have been proven effective in lowering blood pressure levels. Alpha-blockers offer a targeted approach to address the specific mechanisms involved in hypertension, allowing for precise blood pressure control. They work by inhibiting the ...
Source: The EMT Spot - July 17, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Yoghurt: A Delicious Solution To High Blood Pressure?
Conclusion In a nutshell, the humble pot of yoghurt could be a powerful tool in the fight against high blood pressure. From its impressive mineral content to the potential blood-pressure-lowering action of its amino acids, yoghurt has proven to be more than just a tasty snack. However, as we’ve learned from Dr. Lee, the type and quantity of yoghurt we consume matters. The takeaway? Dietary choices can significantly impact our health, making conscious consumption essential. Now, you might view that bowl of yoghurt in a new light, not only for its delicious taste but also for its potential health-...
Source: The EMT Spot - July 16, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer'...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Late Life Rapamycin Treatment Reverses Diastolic Dysfunction in Mice
Inhibitors of mTOR such as rapamycin are increasingly well studied. This class of drug stimulates cellular stress responses, principally autophagy, and thus produces outcomes that are broadly similar to the long-term improvement of health resulting from calorie restriction, exercise, or other demonstrated means of upregulating autophagy. This results in benefits to health, such as those noted in today's open access paper. It is one thing to demonstrate that a drug improves measures of autophagy known to decline with age, and note that many of the interventions shown to modestly slow aging in laboratory species are c...
Source: Fight Aging! - July 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Angiotensin II Receptor Blockers (ARBs) For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion Cardiovascular disease (CVD) has become a leading cause of death globally, necessitating the adoption of preventive measures, early detection, and effective management strategies. Hypertension, a significant risk factor for CVD, requires active management to mitigate associated risks. Angiotensin II Receptor Blockers (ARBs) have emerged as a favored choice among healthcare professionals due to their effectiveness and unique benefits. ARBs offer several advantages compared to other blood pressure medications. They effectively control blood pressure, protect vital organs such as the heart and kidneys, ...
Source: The EMT Spot - July 11, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

ACE Inhibitors For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In conclusion, the rising utilization of blood pressure medications reflects a growing awareness of the importance of managing hypertension for overall health. ACE inhibitors, among other drug classes, are widely used due to their effectiveness in lowering blood pressure and providing additional benefits for heart and kidney health. It’s essential to consult your doctor before starting or adjusting ACE inhibitor treatment to ensure personalized care and monitor for potential side effects or drug interactions. Taking ACE inhibitors as prescribed, following consistent dosing schedules, and attend...
Source: The EMT Spot - July 9, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Navitus 2022 Drug Trend Report
   Its been many years since I posted news of a PBM Drug Trend Report. Once upon a time, PBM drug trend reports contained lots of interesting information. However, over time (in 2021, for example, when reports from the preceding year were published), CVS Caremark published only a bare-bones summary, while Prime Therapeutics, MedImpact, and other large PBMs all completelystopped publishing drug trend reports. The reason is basically because its becoming harder and harder for PBMs to present themselves as saving money when the biggest PBMs aren ' t saving any entities any money on prescription drugs anymore (I...
Source: Scott's Web Log - July 5, 2023 Category: Endocrinology Tags: 2022 2023 Drug Trend Report Navitus Navitus Health Solutions PBM Source Type: blogs

Thinking New Thoughts about the Human Brain | TAPP 139
In Episode 139, we explore anew discovery in nerve signaling in the brain called adendritic action potential (dCaAP), we look at a whackyproposed model of brain function, and we share some ideas about how we can help our students understand thecore concepts ofchemical signaling andsignal transduction in different contexts. Put on your thinking caps and jump into this fresh episode now.00:00 | Introduction00:50 | Dendritic Action Potentials12:16 | Transducer Model of the Brain21:43 | Chemical Signals& Signal Transduction35:09 | Staying Connected ★ If you cannot see or activate the audio player, go to:theAPprofess...
Source: The A and P Professor - June 28, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs

Ultrahigh-Resolution Photon-counting CT Useful Prior to Transcatheter Aortic Valve Replacement
Assessment of coronary anatomy prior to Transcatheter Aortic Valve Replacement has great prognostic significance. Invasive coronary angiography is done prior to TAVR though CT coronary angiography has a role in ruling out coronary artery disease in those with low or intermediate pretest probabilities. Accurate interpretation of coronary arteries in those planned for TAVR has challenges because of high occurrence of abnormal heart rhythm, contraindications for beta blockers and nitroglycerine administraton. Still important is the blooming artifacts on CT coronary angiography in those with coronary stents or severe calcific...
Source: Cardiophile MD - June 21, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Pump Up the Potassium
The element potassium plays a pivotal role in our bodies. It’s found in all our cells, where it regulates their volume and pressure. To do this, our bodies carefully control potassium levels so that the concentration is about 30 times higher inside cells than outside. Potassium works closely with sodium, which regulates the extracellular fluid volume and has a higher concentration outside cells than inside. These concentration differences create an electrochemical gradient, or a membrane potential. Potassium is the primary regulator of the pressure and volume inside cells, and it’s important for nerve transmiss...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 21, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Molecular Structures Cellular Processes Element Proteins Source Type: blogs

Can You Follow A Vegan Diet With Hypertension?
Conclusion Returning to our original question—can you follow a vegan diet with hypertension?—current research suggests a tentative ‘yes.’ With thoughtful planning and balanced nutrition, the potential benefits can outweigh the challenges. However, it’s vital to remember that managing hypertension is a multifaceted undertaking, and dietary changes should be just one part of a comprehensive lifestyle and medical management plan. Read also: Can You Consume High-Sodium Foods With Hypertension? Reference Vegetarian Diets and Blood Pressure Among White Subjects: Results from the Adventist H...
Source: The EMT Spot - June 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs