St. John ’ s Wort: A Hidden Danger For Hypertension?
Conclusion: Navigating The Use Of St. John’s Wort Amidst Hypertension While St. John’s Wort is generally safe for most people, it may pose challenges for individuals managing high blood pressure, especially those on specific medications, such as calcium blockers. Reflecting on Trista Best’s wisdom, informed decision-making and regular healthcare consultations are key to safely traversing the landscape of supplements. As we continually unearth the potentials of these natural remedies, balancing their benefits and risks is fundamental to our health journey. This in-depth understanding helps ensur...
Source: The EMT Spot - June 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Nocturnal Hypertension Unveiled: Protect Your Health While You Sleep
Is your blood pressure working the night shift? Let’s decode the mysteries of nocturnal hypertension together – from its symptoms and causes, to diagnosis and effective management. Sleep peacefully with our handy guide! Quick Summary Nocturnal Hypertension refers to high blood pressure that occurs at night, usually when blood pressure should naturally dip due to the circadian rhythm. Risk factors for nocturnal hypertension include conditions such as sleep apnea, diabetes, kidney disease, and lifestyle factors like high salt intake and lack of adequate sleep. Diagnosis and management of nocturna...
Source: The EMT Spot - June 3, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Masked Hypertension: Your Silent Health Threat
Conclusion Masked hypertension is a silent threat that occurs when normal blood pressure readings at the doctor’s office conceal high readings at home or elsewhere. Although the precise cause remains uncertain, factors like smoking, excessive alcohol, and work-related stress appear to play a role. Despite the symptomless nature of this condition, regular monitoring of blood pressure can help detect and manage it effectively, preventing serious complications. Regular lifestyle modifications and prescribed medications can help keep this masked menace at bay. References Cuspidi, C., et al. (2023). Masked hy...
Source: The EMT Spot - May 30, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

20-something with huge verapamil overdose and cardiogenic shock
A 20-something presented after a huge verapamil overdose in cardiogenic shock.  He had been seen at an outside institution and been given 6 g calcium gluconate, KCl, and a norepinephrine drip.The initial K was 3.0 mEq/L and ionized calcium was 5.5 mg/dL (sorry, Europeans, for the weird units)Here was the initial ED ECG:There is a junctional rhythm with retrograde P-waves (see the dip in the T-wave in lead II across the bottom; you can follow that up to all the other leads and see the retrograde P wave).  There is also Left Bundle Branch Block (LBBB). There is huge proportionally excessively discord...
Source: Dr. Smith's ECG Blog - May 26, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

10 Effective Blood Pressure Treatment Methods: Your Essential Guide To Beating Hypertension
Conclusion To summarize, early detection by watching out for symptoms of high blood pressure and prompt action are vital when it comes management. Consulting a doctor to identify the cause of hypertension and addressing it at the root is crucial in preventing its recurrence. While lifestyle factors contribute significantly to its development, high blood pressure can also coexist as a comorbidity with other health conditions. While prescription medications prescribed by a doctor are highly effective, alternative approaches can be considered for non-critical conditions. Incorporating lifestyle changes, such as...
Source: The EMT Spot - May 16, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

10 Effective High Blood Pressure Treatment Methods: Your Essential Guide To Beating Hypertension
Conclusion To summarize, early detection by watching out for symptoms of high blood pressure and prompt action are vital when it comes management. Consulting a doctor to identify the cause of hypertension and addressing it at the root is crucial in preventing its recurrence. While lifestyle factors contribute significantly to its development, high blood pressure can also coexist as a comorbidity with other health conditions. While prescription medications prescribed by a doctor are highly effective, alternative approaches can be considered for non-critical conditions. Incorporating lifestyle changes, such as...
Source: The EMT Spot - May 16, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, May 15th 2023
In this study, we examined the average telomere length and telomerase activity, as well as the formation of telomere associated foci (TAFs) and the mRNA expression levels of the shelterin components in cultured primary cells of Spalax, a long-lived, hypoxia-tolerant, and cancer-resistant blind mole-rat species. We showed that with cell passages, Spalax fibroblasts demonstrated significant shortening in telomere length, similar to rat cells, and in line with the processes observed earlier in tissues. We also demonstrated that the average telomere length in Spalax fibroblasts was significantly higher than the average ...
Source: Fight Aging! - May 14, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mushroom Magic: A Natural Remedy For High Blood Pressure?
Conclusion So there you have it, folks! Mushrooms aren’t just delicious; they’re also potentially a secret weapon in our fight against hypertension. By incorporating mushrooms into your diet, you’re not just treating your taste buds, but you’re also taking a proactive step towards better heart health. But remember, while mushrooms and their bioactive compounds show great promise, they’re not an alternative to medical treatment. They’re a dietary intervention, a way to supplement the efforts you’re already making to manage hypertension. As always, if you have c...
Source: The EMT Spot - May 13, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Mitochondrial Dysfunction as a Feature of Neurodegenerative Conditions
Increasing dysfunction of mitochondria, the power plants of the cell, is a feature of aging. It is also strongly connected to neurodegenerative conditions. The brain is an energy-hungry organ, and anything that interferes with the supply of nutrients and their processing to power cellular operations is going to cause issues. In this review paper, researchers discuss the link between mitochondrial dysfunction and neurodegeneration, and go on to note a few of the efforts underway to produce pharmacological treatments capable of restoring greater mitochondrial function in aged tissues. Sadly all too few of these treatments ca...
Source: Fight Aging! - May 9, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Technology Can Help Us Achieve Health Equity
There has been an incredible rise in technological advancements in the world of healthcare recently due to our sudden need for everything to be digital when COVID hit. While the cases of COVID have gone down and we’ve settled into a new normal, that isn’t the only crisis that we need a tech fix too. We need to start searching for how we can use technology, new or old, to fix health inequality and discrimination. We reached out to our beautiful Healthcare IT Today Community to get their insights on the role technology can play in working towards health equity. The following is what they had to say and be sure to...
Source: EMR and HIPAA - May 5, 2023 Category: Information Technology Authors: John Lynn Tags: C-Suite Leadership Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops Regulations Alex Rothberg Andrew Kobylinski Ben Zaniello MD Bronwyn Spira Cardio Diagnosti Source Type: blogs

Do Blood Pressure Supplements Interact With Any Foods Or Drinks?
Conclusion To sum things up, blood pressure supplements are a safe and effective option for managing hypertension, and they typically do not interact with most foods and drinks. However, some fruits and beverages may reduce the effectiveness of natural supplements. To ensure that you receive the maximum benefit from your blood pressure supplements, avoiding certain foods and drinks is essential. Licorice, grapefruit, and alcohol are among the top culprits that can interfere with the efficacy of supplements and cause negative side effects. High-fat meals and salt substitutes containing potassium can also hinder ...
Source: The EMT Spot - May 3, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Supplements Source Type: blogs

Optum Store Opting Out of Direct-to-Consumer Pharmacy Biz
Last November [2022], I blogged (see my post athttps://blog.sstrumello.com/2022/11/cigna-express-scripts-by-insiderx.html for reference) how Cigna ' s Express Scripts was discontinuing the company ' s cash-pay mail order pharmacy by InsideRx (the coupon website/app is owned by Express Scripts). Well, now rival United Healthcare ' s OptumRx is doing the same, effectively shutting down its Optum Store. Have a look at this notice:I know it ' s impossible to read, but the first paragraph reads:" We ' re sad to say that starting June 1st, 2023, you will no longer be able to fill prescriptions through the Optum Store except...
Source: Scott's Web Log - May 2, 2023 Category: Endocrinology Tags: 2023 Diabetes Mine Express Scripts by InsideRx Healthline Optum Optum Store OptumRx RVO Health LLC United Healthcare Source Type: blogs

Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved. Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

More Details on Cyclarity's Approach to Clearing 7-Ketocholesterol
This recent article from the SENS Research Foundation discusses calcium chelation and, separately, the tailored cyclodextrin molecules developed by Cyclarity to sequester 7-ketocholesterol. This altered form of cholesterol is toxic to cells, and may provide a significant contribution to a range of age-related conditions, including atherosclerosis. Cyclarity will be conducting initial human trials in the near future. Since the best way to determine exactly how important 7-ketocholesterol is in the context of atherosclerosis in humans is to remove it, it will be interesting to see how this goes. It is vital to progress that ...
Source: Fight Aging! - April 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs