Burkholderia gladioli deep pyoderma in a dog secondary to immunosuppressive ciclosporin and prednisone therapy
Vet Dermatol. 2024 Apr 23. doi: 10.1111/vde.13254. Online ahead of print.ABSTRACTA dog presented with deep pyoderma on the paw, following treatment with ciclosporin and prednisone for immune-mediated haemolytic anaemia. Cytological evaluation, skin biopsy, aerobic culture, next-generation DNA sequencing and PCR were used to detect the first reported case of Burkholderia gladioli in a dog.PMID:38654610 | DOI:10.1111/vde.13254 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 24, 2024 Category: Veterinary Research Authors: Wayne Rosenkrantz Jana M Ritter M Kelly Keating Julu Bhatnagar Janina A Krumbeck Source Type: research
Burkholderia gladioli deep pyoderma in a dog secondary to immunosuppressive ciclosporin and prednisone therapy
Vet Dermatol. 2024 Apr 23. doi: 10.1111/vde.13254. Online ahead of print.ABSTRACTA dog presented with deep pyoderma on the paw, following treatment with ciclosporin and prednisone for immune-mediated haemolytic anaemia. Cytological evaluation, skin biopsy, aerobic culture, next-generation DNA sequencing and PCR were used to detect the first reported case of Burkholderia gladioli in a dog.PMID:38654610 | DOI:10.1111/vde.13254 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 24, 2024 Category: Veterinary Research Authors: Wayne Rosenkrantz Jana M Ritter M Kelly Keating Julu Bhatnagar Janina A Krumbeck Source Type: research
Jian Gan powder ameliorates immunological liver injury in mice by modulating the gut microbiota and metabolic profiles
ConclusionsJGP intervention improves ILI by restoring gut microbiota and modifying its metabolic profiles. These results provide a novel insight into the mechanism of JGP in treating ILI and the scientific basis to support its clinical application. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 20, 2024 Category: Research Source Type: research
Burkholderia thailandensis uses a type VI secretion system to lyse protrusions without triggering host cell responses
Cell Host Microbe. 2024 Apr 16:S1931-3128(24)00113-6. doi: 10.1016/j.chom.2024.03.013. Online ahead of print.ABSTRACTTo spread within a host, intracellular Burkholderia form actin tails to generate membrane protrusions into neighboring host cells and use type VI secretion system-5 (T6SS-5) to induce cell-cell fusions. Here, we show that B. thailandensis also uses T6SS-5 to lyse protrusions to directly spread from cell to cell. Dynamin-2 recruitment to the membrane near a bacterium was followed by a short burst of T6SS-5 activity. This resulted in the polymerization of the actin of the newly invaded host cell and disruption...
Source: Cell Host and Microbe - April 19, 2024 Category: Microbiology Authors: Miro Thorsten Wilhelm Plum Hoi Ching Cheung Patricia Reist Iscar Yahua Chen Yunn-Hwen Gan Marek Basler Source Type: research
< em > Burkholderia pseudomallei < /em > pericarditis as a mimicker of tuberculous pericarditis: a case report
Hong Kong Med J. 2024 Apr 17. doi: 10.12809/hkmj2310671. Online ahead of print.NO ABSTRACTPMID:38629321 | DOI:10.12809/hkmj2310671 (Source: Hong Kong Medical Journal)
Source: Hong Kong Medical Journal - April 17, 2024 Category: General Medicine Authors: F H C Lau M F Lin W S Ng Source Type: research
< em > Burkholderia pseudomallei < /em > pericarditis as a mimicker of tuberculous pericarditis: a case report
Hong Kong Med J. 2024 Apr;30(2):167-169. doi: 10.12809/hkmj2310671. Epub 2024 Apr 17.NO ABSTRACTPMID:38629321 | DOI:10.12809/hkmj2310671 (Source: Hong Kong Med J)
Source: Hong Kong Med J - April 17, 2024 Category: General Medicine Authors: F H C Lau M F Lin W S Ng Source Type: research
< em > Burkholderia pseudomallei < /em > pericarditis as a mimicker of tuberculous pericarditis: a case report
Hong Kong Med J. 2024 Apr;30(2):167-169. doi: 10.12809/hkmj2310671. Epub 2024 Apr 17.NO ABSTRACTPMID:38629321 | DOI:10.12809/hkmj2310671 (Source: Hong Kong Medical Journal)
Source: Hong Kong Medical Journal - April 17, 2024 Category: General Medicine Authors: F H C Lau M F Lin W S Ng Source Type: research
Molecular characterization and evaluation of novel management options for Burkholderia glumae BG1, the causative agent of panicle blight of rice (Oryza sativa L.)
CONCLUSIONS: Overall, our study provides valuable insights into the potential and practical application of nano copper for the mitigation of bacterial panicle blight, offering promising prospects for commercial utilization in disease management.PMID:38625424 | DOI:10.1007/s11033-024-09498-2 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 16, 2024 Category: Molecular Biology Authors: Bhaskaran Sreenayana Kalyan Kumar Mondal Nivetha Mathiyalagan Kalaivanan Nagaranai Shanmugam Sanjeev Kumar Mrutyunjaya Shrinivas Reddy Chander Mani Source Type: research
A < em > Burkholderia cenocepacia < /em > -like environmental isolate strongly inhibits the plant fungal pathogen < em > Zymoseptoria tritici < /em >
Appl Environ Microbiol. 2024 Apr 16:e0222223. doi: 10.1128/aem.02222-23. Online ahead of print.ABSTRACTFungal phytopathogens cause significant reductions in agricultural yields annually, and overusing chemical fungicides for their control leads to environmental pollution and the emergence of resistant pathogens. Exploring natural isolates with strong antagonistic effects against pathogens can improve our understanding of their ecology and develop new treatments for the future. We isolated and characterized a novel bacterial strain associated with the species Burkholderia cenocepacia, termed APO9, which strongly inhibits Zy...
Source: Applied and Environmental Microbiology - April 16, 2024 Category: Microbiology Authors: Tingting Song Suyash Gupta Yael Sorokin Omer Frenkel Eddie Cytryn Jonathan Friedman Source Type: research
Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to Burkholderia pseudomallei, a lung-tropic pathogen
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
Source: Infection and Immunity - April 15, 2024 Category: Infectious Diseases Authors: Lara Lovelace-MaconSarah M. BakerDeirdre DuckenSudeshna SealGuilhem RerolleDiane TomitaKelly D. SmithSandra SchwarzT. Eoin West1Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington Source Type: research
Hospital-acquired pneumonia due to Burkholderia cepacia in a thalassemia pregnancy with postoperative eclampsia: A case report
Respir Med Case Rep. 2024 Apr 4;49:102021. doi: 10.1016/j.rmcr.2024.102021. eCollection 2024.ABSTRACTThere are limited case reports on individuals infected with Burkholderia cepacia who do not have typical risk factors, particularly pregnant women with beta-thalassemia. A 34-year-old pregnant female with beta-thalassemia trait and hypertension was admitted to the hospital. The patient was diagnosed with eclampsia and underwent a cesarean section. After two days following the surgery, the patient experienced hospitality-acquired pneumonia. B.cepacia was isolated from blood cultures, and antibiotic susceptibility testing ind...
Source: Respiratory Care - April 11, 2024 Category: Respiratory Medicine Authors: Khoa Nguyen-Dang Ngoc Duong-Minh Hanh-Duyen Bui-Thi Source Type: research
Hospital-acquired pneumonia due to Burkholderia cepacia in a thalassemia pregnancy with postoperative eclampsia: A case report
Respir Med Case Rep. 2024 Apr 4;49:102021. doi: 10.1016/j.rmcr.2024.102021. eCollection 2024.ABSTRACTThere are limited case reports on individuals infected with Burkholderia cepacia who do not have typical risk factors, particularly pregnant women with beta-thalassemia. A 34-year-old pregnant female with beta-thalassemia trait and hypertension was admitted to the hospital. The patient was diagnosed with eclampsia and underwent a cesarean section. After two days following the surgery, the patient experienced hospitality-acquired pneumonia. B.cepacia was isolated from blood cultures, and antibiotic susceptibility testing ind...
Source: Respiratory Care - April 11, 2024 Category: Respiratory Medicine Authors: Khoa Nguyen-Dang Ngoc Duong-Minh Hanh-Duyen Bui-Thi Source Type: research
Melioidosis masquerading as malignancy in tropical Australia; lessons for clinicians and implications for clinical management
We present a case series of 7 patients from tropical Australia whom local clinicians initially believed to have cancer ‒ most commonly lung cancer ‒ only for further investigation to establish a diagnosis of melioidosis. All 7 patients had comorbidities that predisposed them to developing melioidosis and all survived, but their delayed diagnosis resulted in 3 receiving anti-cancer therapies that resulted in significant morbidity. The study emphasises the importance of thorough diagnostic evaluation and repeated collection of microbiological samples. It is hoped that our experience will encourage other clinicians ‒ in...
Source: Acta Tropica - April 10, 2024 Category: Infectious Diseases Authors: Kelly Baker Ty Duncan Samantha Kung Simon Smith Josh Hanson Source Type: research
Melioidosis masquerading as malignancy in tropical Australia; lessons for clinicians and implications for clinical management
We present a case series of 7 patients from tropical Australia whom local clinicians initially believed to have cancer ‒ most commonly lung cancer ‒ only for further investigation to establish a diagnosis of melioidosis. All 7 patients had comorbidities that predisposed them to developing melioidosis and all survived, but their delayed diagnosis resulted in 3 receiving anti-cancer therapies that resulted in significant morbidity. The study emphasises the importance of thorough diagnostic evaluation and repeated collection of microbiological samples. It is hoped that our experience will encourage other clinicians ‒ in...
Source: Acta Tropica - April 10, 2024 Category: Infectious Diseases Authors: Kelly Baker Ty Duncan Samantha Kung Simon Smith Josh Hanson Source Type: research
