Obituary for Professor Michael J. Day.
PMID: 32613668 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - July 1, 2020 Category: Veterinary Research Authors: Foster A Tags: Vet Dermatol Source Type: research

A comparative study of subcutaneous, intralymphatic and sublingual immunotherapy for the long-term control of dogs with nonseasonal atopic dermatitis.
Abstract BACKGROUND: Allergen-specific immunotherapy (ASIT) is the only causative treatment of canine atopic dermatitis (cAD). Different routes for administration of ASIT have been used; however, comparative studies are lacking. HYPOTHESIS/OBJECTIVES: The present study compared the efficacy and safety of subcutaneous (SCIT), intralymphatic (ILIT) and sublingual (SLIT) immunotherapy. ANIMALS: 30 atopic dogs were included and allocation to three groups (SCIT, n = 8; ILIT, n = 12; SLIT, n = 10) was determined by the owners. METHODS AND MATERIALS: ASIT was administered usin...
Source: Veterinary Dermatology - June 14, 2020 Category: Veterinary Research Authors: Fischer NM, Rostaher A, Favrot C Tags: Vet Dermatol Source Type: research

Efficacy of oral sarolaner against Lynxacarus radovskyi in naturally infested cats.
CONCLUSION: A single oral dose of sarolaner effectively eliminated L. radovskyi in most cats. PMID: 32497276 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - June 4, 2020 Category: Veterinary Research Authors: Campos DR, Chaves JKO, Assis RCP, Fernandes JI, Scott FB Tags: Vet Dermatol Source Type: research

Equine herpesvirus-1 associated ulcerative dermatitis in a horse.
vé F Abstract This case report describes the clinical and histopathological findings of an infection caused by equine herpesvirus-1 (EHV-1) in a horse showing respiratory signs and a papular, crusted, and ulcerative dermatitis involving mucosa. This diagnosis was supported by real-time polymerase chain reaction positive for EHV-1 on nasal swabs and tissues. PMID: 32479674 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - June 1, 2020 Category: Veterinary Research Authors: Bergeron CC, Allano M, Cluzel C, Doré M, Sauvé F Tags: Vet Dermatol Source Type: research

A pilot study to identify perceived barrier and motivating factors of primary veterinarians for specialty referral and management of atopic dermatitis with allergen-specific immunotherapy.
CONCLUSIONS AND CLINICAL SIGNIFICANCE: Numerous factors appear to influence decisions to recommend referral or ASIT for management of pets with cAD. Further work is needed to determine if these can be generalized to larger populations with a goal of providing suggestions to bridge these gaps and improve outcomes. PMID: 32416025 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - May 16, 2020 Category: Veterinary Research Authors: Flanagan S, Schick A, Lewis TP Tags: Vet Dermatol Source Type: research

Detection of circulating  antikeratinocyte autoantibodies in feline pemphigus foliaceus.
Detection of circulating antikeratinocyte autoantibodies in feline pemphigus foliaceus. Vet Dermatol. 2020 May 06;: Authors: Levy BJ, Mamo LB, Bizikova P Abstract BACKGROUND: Circulating anti-keratinocyte immunoglobulin (Ig)G targeting desmosomal proteins have been identified in people and dogs with pemphigus foliaceus (PF). By contrast, detection attempts in PF-affected cats have been largely unsuccessful. HYPOTHESIS/OBJECTIVES: To detect circulating anti-keratinocyte autoantibodies in PF-affected cats and determine their titres and tissue-staining patterns. ANIMALS: Thirty PF-affected...
Source: Veterinary Dermatology - May 6, 2020 Category: Veterinary Research Authors: Levy BJ, Mamo LB, Bizikova P Tags: Vet Dermatol Source Type: research

Equine pythiosis in Egypt: clinicopathological findings, detection, identification and genotyping of Pythium insidiosum.
CONCLUSIONS AND CLINICAL IMPORTANCE: Direct sample multiplex-PCR assay is a potential tool for the early and rapid diagnosis of equine pythiosis. It overcomes limitations associated with morphological identification and provides a definitive diagnosis. PMID: 32342602 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 28, 2020 Category: Veterinary Research Authors: Tartor YH, Hamad MH, Abouzeid NZ, El-Belkemy FA Tags: Vet Dermatol Source Type: research

Cutaneous polyautoimmunity in two unrelated dogs: pemphigus foliaceus and generalized discoid lupus erythematosus.
CONCLUSIONS AND CLINICAL IMPORTANCE: Cutaneous polyautoimmunity can occur in the dog. Depending on the specific disease combinations, overlapping clinical features may present diagnostic and/or therapeutic challenges. Moreover, these cases should be monitored for development of additional cutaneous or extra-cutaneous AD(s). PMID: 32342582 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 27, 2020 Category: Veterinary Research Authors: Levy BJ, Linder KE, Mamo LB, Herrmann I, Bizikova P Tags: Vet Dermatol Source Type: research

Clindamycin resistance of skin derived Staphylococcus pseudintermedius is higher in dogs with a previous antibiotic history.
CONCLUSIONS: Given the high prevalence of clindamycin resistance in MSSP isolated from dogs with prior antimicrobial exposure, it is recommended that bacterial culture and susceptibility testing be pursued before prescribing systemic antimicrobials. Clindamycin should be regarded as the preferred treatment option if susceptibility is confirmed, due to its narrow spectrum and reduced selective pressure for MRSP. PMID: 32323363 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 22, 2020 Category: Veterinary Research Authors: van Damme CMM, Broens EM, Auxilia ST, Schlotter YM Tags: Vet Dermatol Source Type: research

Chrysomya bezziana (Diptera: Calliphoridae) infestation in two Malaysian cats treated with oral lotilaner.
Abstract The most common fly species associated with screwworm myiasis in Southeast Asia is Chrysomya bezziana (Ch. bezziana), the Old-World screwworm. Treatment of screwworm myiasis in cats traditionally has comprised subcutaneous injection of ivermectin or oral administration of nitenpyram, combined with aggressive tissue debridement and larval removal under general anaesthesia. Two cats diagnosed with cutaneous myiasis caused by the larvae of Ch. bezziana were treated with lotilaner. In both cats, a single dose of lotilaner at 6-26 mg/kg, killed all larvae within 24 h, negating the need for ...
Source: Veterinary Dermatology - April 22, 2020 Category: Veterinary Research Authors: Han HS, Yasmin L Tags: Vet Dermatol Source Type: research

Efficacy of three disinfectant formulations and a hydrogen peroxide/silver fogging system on surfaces experimentally inoculated with meticillin-resistant Staphylococcus pseudintermedius.
Abstract BACKGROUND: Effective environmental disinfection is necessary to prevent nosocomial infections from meticillin-resistant Staphylococcus pseudintermedius (MRSP). However, there are currently no commercial disinfectant sprays or fogging systems with label claims against MRSP. HYPOTHESIS/OBJECTIVES: To evaluate the efficacy of a quaternary ammonium product (QAC), an accelerated hydrogen peroxide product (AHP), a hydrogen peroxide and silver product (HAL), and a hydrogen peroxide and silver fogging system (FOG) against MRSP. METHODS AND MATERIALS: Sterile plastic surfaces inoculated with MRSP were t...
Source: Veterinary Dermatology - April 20, 2020 Category: Veterinary Research Authors: Soohoo J, Daniels JB, Brault SA, Rosychuk RAW, Schissler JR Tags: Vet Dermatol Source Type: research

A case of atypical multifocal nodular eosinophilic dermatosis in a Labrador retriever dog.
CONCLUSIONS AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is a novel nodular clinical and eosinophilic histopathological pattern combination. This case offers evidence of a spectrum of sterile eosinophilic dermatoses rather than multiple different disease processes. PMID: 32307791 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 19, 2020 Category: Veterinary Research Authors: Emery CB, Affolter VK, Outerbridge CA, Lam ATH, White SD Tags: Vet Dermatol Source Type: research

Rapid response of hyperkeratotic erythema multiforme to oclacitinib in two dogs.
CONCLUSION AND CLINICAL IMPORTANCE: Oclacitinib could be considered as a fast-acting and effective treatment option for HKEM in dogs. PMID: 32307815 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 19, 2020 Category: Veterinary Research Authors: High EJ, Linder KE, Mamo LB, Levy BJ, Herrmann I, Bizikova P Tags: Vet Dermatol Source Type: research

Comparison of various treatment options for canine atopic dermatitis: a blinded, randomized, controlled study in a colony of research atopic beagle dogs.
CONCLUSIONS AND CLINICAL IMPORTANCE: Lokivetmab prevented flares when given before challenge. Oclacitinib and lokivetmab have some positive effects on skin barrier parameters. PMID: 32301565 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 17, 2020 Category: Veterinary Research Authors: Marsella R, Ahrens K, Wilkes R, Trujillo A, Dorr M Tags: Vet Dermatol Source Type: research

Long-lasting successful treatment of a donkey with cutaneous lupus erythematous with methotrexate.
Abstract Cutaneous lupus erythematosus (CLE) is a rare immune-mediated dermatitis. To the best of the authors' knowledge it has not been described in donkeys. A 5-year-old male neutered donkey, living in south-east France, was diagnosed with CLE. Clinical signs included generalized symmetrical areas of alopecia, erythema, crusting and scales. Diagnostic tests included examination of skin biopsy samples by histopathological and immunohistochemical analysis which demonstrated an interface dermatitis with CD8+ T cells. The skin condition was successfully treated initially with glucocorticoids and methotrexate; succes...
Source: Veterinary Dermatology - April 15, 2020 Category: Veterinary Research Authors: Mosca M, Randleff-Rasmussen P, Milhau N, Panzuti P, Meylan M, Desjardin I, Pin D Tags: Vet Dermatol Source Type: research

Acral congenital superficial dermal lymphatic malformations in two unrelated cats: clinicopathological, dermoscopic and ultrastructural findings.
CONCLUSION AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first description of the clinical, dermoscopic, histopathological and ultrastructural characteristics of SDCLM in cats resembling the human counterpart. SDCLMs are rare conditions and appropriate histopathological and immunohistochemical confirmation is required to avoid misdiagnosis and mistreatment. PMID: 32249482 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 6, 2020 Category: Veterinary Research Authors: Legnani S, Abramo F, Zanna G, Graziano L, Cornegliani L, Roccabianca P Tags: Vet Dermatol Source Type: research

Invasive histiocytoma in the ear canal of a dog.
CONCLUSIONS AND CLINICAL IMPORTANCE: Although single CH are typically associated with benign behaviour, the mass in this dog demonstrated locally invasive behaviour. Cutaneous histiocytomas in the ear canals of dogs may represent a particularly aggressive variant of the condition. PMID: 32249514 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - April 6, 2020 Category: Veterinary Research Authors: Fernandez M, Boudreaux BB, Wilson L, Moore PF, Rademacher N, Pucheu-Haston C Tags: Vet Dermatol Source Type: research

Corrigendum.
Authors: PMID: 32153081 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - March 12, 2020 Category: Veterinary Research Tags: Vet Dermatol Source Type: research

Addendum.
Authors: PMID: 32153082 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - March 12, 2020 Category: Veterinary Research Tags: Vet Dermatol Source Type: research

Identification of fusidic acid resistance in clinical isolates of Staphylococcus pseudintermedius from dogs in Korea.
Abstract BACKGROUND: Staphylococcus pseudintermedius is a major bacterial species associated with canine pyoderma and otitis. Fusidic acid is used to treat skin infections caused by Gram-positive bacteria. The incidence of resistance to fusidic acid in S. pseudintermedius has importance in terms of limiting treatment options for bacterial infections. HYPOTHESIS/OBJECTIVES: To evaluate the occurrence and mechanisms of fusidic acid resistance in clinical isolates of S. pseudintermedius. ANIMALS: Fifty-two S. pseudintermedius isolates were collected from dogs with pyoderma (n = 36) ...
Source: Veterinary Dermatology - March 1, 2020 Category: Veterinary Research Authors: Lim YJ, Hyun JE, Hwang CY Tags: Vet Dermatol Source Type: research

Atopic dermatitis in a cohort of West Highland white terriers in Switzerland. Part II: estimates of early life factors and heritability.
CONCLUSION AND CLINICAL IMPORTANCE: These results suggest that several environmental factors could influence the development of cAD but clearly demonstrate the genetic influence of the individual and the dam. Further studies are needed to identify specific environmental factors, which could be potential targets for primary disease intervention. PMID: 32077169 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - February 19, 2020 Category: Veterinary Research Authors: Rostaher A, Dolf G, Fischer NM, Silaghi C, Akdis C, Zwickl L, Audergon S, Favrot C Tags: Vet Dermatol Source Type: research

Editorial.
PMID: 31957201 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 22, 2020 Category: Veterinary Research Authors: Lloyd D Tags: Vet Dermatol Source Type: research

Diagnosis and treatment of demodicosis in dogs and cats: Clinical consensus guidelines of the World Association for Veterinary Dermatology.
CONCLUSIONS: In young dogs with generalized demodicosis, genetic and immunological factors seem to play a role in the pathogenesis and affected dogs should not be bred. In old dogs and cats, underlying immunosuppressive conditions contributing to demodicosis should be explored. Deep skin scrapings are the diagnostic gold standard for demodicosis, but trichograms and tape squeeze preparations may also be useful under certain circumstances. Amitraz, macrocyclic lactones and more recently isoxazolines have all demonstrated good efficacy in the treatment of canine demodicosis. Therapeutic selection should be guided by local dr...
Source: Veterinary Dermatology - January 22, 2020 Category: Veterinary Research Authors: Mueller RS, Rosenkrantz W, Bensignor E, Karaś-Tęcza J, Paterson T, Shipstone MA Tags: Vet Dermatol Source Type: research

Biology, diagnosis and treatment of Malassezia dermatitis in dogs and cats: Clinical Consensus Guidelines of the World Association for Veterinary Dermatology.
PMID: 31957203 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 22, 2020 Category: Veterinary Research Authors: Bond R, Morris DO, Guillot J, Bensignor EJ, Robson D, Mason KV, Kano R, Hill PB Tags: Vet Dermatol Source Type: research

Biology, diagnosis and treatment of Malassezia dermatitis in dogs and cats Clinical Consensus Guidelines of the World Association for Veterinary Dermatology.
CONCLUSIONS AND CLINICAL IMPORTANCE: There has been a remarkable expansion of knowledge on Malassezia yeasts and their role in animal disease, particularly since the early 1990's. Malassezia dermatitis in dogs and cats has evolved from a disease of obscurity and controversy on its existence, to now being a routine diagnosis in general veterinary practice. Clinical signs are well recognised and diagnostic approaches are well developed. A range of topical and systemic therapies is known to be effective, especially when predisposing factors are identified and corrected. PMID: 31957204 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 22, 2020 Category: Veterinary Research Authors: Bond R, Morris DO, Guillot J, Bensignor EJ, Robson D, Mason KV, Kano R, Hill PB Tags: Vet Dermatol Source Type: research

Equine pastern vasculitis in a horse associated with a multidrug-resistant Pseudomonas aeruginosa isolate.
CONCLUSIONS AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first report of a pastern vasculitis associated with MRPA and successfully treated with a six week course of enrofloxacin. PMID: 31930603 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 12, 2020 Category: Veterinary Research Authors: Panzuti P, Rocafort Ferrer G, Mosca M, Pin D Tags: Vet Dermatol Source Type: research

Multicentric B-cell lymphoma with presumed paraneoplastic generalized cutaneous sclerosis in a dog.
CONCLUSIONS AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first report of multicentric B-cell lymphoma in a dog with concurrent diffuse cutaneous sclerosis, similar to a human paraneoplastic reaction. PMID: 31930629 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 12, 2020 Category: Veterinary Research Authors: Affolter VK, O'Brien D, Nagle TM, Outerbridge CA Tags: Vet Dermatol Source Type: research

Immediate and residual antifungal activity of compounds used for whole body and adjuvant topical therapy against Microsporum canis: in vitro study.
CONCLUSIONS AND CLINICAL IMPORTANCE: Findings support twice weekly application of enilconazole and lime sulphur and application of adjuvant focal topical therapy daily or every other day. PMID: 31913527 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 8, 2020 Category: Veterinary Research Authors: Moriello KA Tags: Vet Dermatol Source Type: research

Chronic progressive lymphoedema in Friesian horses: suggestive phenotype of affected horses and genome-wide association study.
Abstract BACKGROUND: Chronic progressive lymphoedema (CPL) is a disabling condition affecting various draft horse breeds, including Friesian horses. HYPOTHESIS: The high incidence of CPL in Friesian horses suggests a genetic component and a predisposing phenotype. ANIMALS: For the genomic study, 26 affected and 19 control horses were evaluated. Body measurements were taken from 28 affected and nine control Friesian horses. METHODS AND MATERIALS: Axiom® Equine Genotyping Array with a total of 307,474 single nucleotide polymorphism (SNPs) was used for the case/control genome-wide association study...
Source: Veterinary Dermatology - January 6, 2020 Category: Veterinary Research Authors: Affolter VK, Dalley B, Kass PH, Brown EA, Sonder C, Bannasch DL Tags: Vet Dermatol Source Type: research

Patulous Eustachian tube and palatine defect in a Dachshund with chronic unilateral otitis externa and otitis media.
CONCLUSION AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first case of pET described in animals. The ET dysfunction and palatine defect were likely the cause of the otitis in this dog. Clinicians should investigate pET in animals with signs of OE characterized by frothy liquid and food fragments in the ear canal in addition to sneezing after drinking water. PMID: 31908074 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 6, 2020 Category: Veterinary Research Authors: Koch SN, Torres SMF, Kramek B Tags: Vet Dermatol Source Type: research

Granulomatous mural folliculitis in a dog treated with ciclosporin and methotrexate.
CONCLUSIONS AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first report of the long-term management of a granulomatous mural folliculitis in a dog. Ciclosporin and MTX appeared to be an effective treatment option. Additional treated cases are needed to assess the effectiveness of MTX in canine immune-mediated diseases. PMID: 31908101 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 6, 2020 Category: Veterinary Research Authors: Panzuti P, Mosca M, Pin D Tags: Vet Dermatol Source Type: research

Is a de novo nonsense variant in the ASPDH gene the cause of ulcerative skin lesions in a Holstein calf?
CONCLUSION AND CLINICAL IMPORTANCE: The observed phenotype in the calf may represent a novel form of a vesicular skin disorder. Haploinsufficiency of the ASPDH gene might be considered as a possible cause. PMID: 31908106 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 6, 2020 Category: Veterinary Research Authors: Brunner MAT, Veiga IMB, Niggeler A, Häfliger IM, Stettler M, Meylan M, Welle M, Drögemüller C Tags: Vet Dermatol Source Type: research

Efficacy of a Bruton's Tyrosine Kinase Inhibitor (PRN-473) in the treatment of canine pemphigus foliaceus.
CONCLUSIONS AND CLINICAL IMPORTANCE: BTKi monotherapy may have beneficial effects in some cases of cPF. PMID: 31899567 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 3, 2020 Category: Veterinary Research Authors: Goodale EC, Varjonen KE, Outerbridge CA, Bizikova P, Borjesson D, Murrell DF, Bisconte A, Francesco M, Hill RJ, Masjedizadeh M, Nunn P, Gourlay SG, White SD Tags: Vet Dermatol Source Type: research

Effect of diphenhydramine and cetirizine on immediate and late phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study.
CONCLUSION AND CLINICAL SIGNIFICANCE: In conclusion, oral cetirizine was effective in preventing cutaneous allergic reactions without any obvious adverse effects in dogs. Oral DPH failed to show an inhibitory effect despite attaining plasma drug concentrations that are considered effective in people. PMID: 31899570 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 3, 2020 Category: Veterinary Research Authors: Banovic F, Denley T, Blubaugh A, Scheibe I, Lemo N, Papich MG Tags: Vet Dermatol Source Type: research

Evaluation of hair follicle parameters using TrichoScale Pro © in healthy dogs: a pilot study.
CONCLUSIONS: While it provides less useful data for canine hair coats than for human scalp hair, the system evaluated provides an easy, non-invasive, rapid means for assessing several important canine hair follicle parameters: daily hair growth rates, anagen and telogen percentages, primary and secondary hair percentages, and mean hair thickness. This diagnostic tool could serve to establish breed-specific hair coat standards, evaluating hair follicle changes in various canine alopecic conditions, and monitoring coat-promoting treatments in dogs. PMID: 31898370 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 2, 2020 Category: Veterinary Research Authors: Schuldenfrei MD, Pieper JB Tags: Vet Dermatol Source Type: research

Recovery of meticillin-resistant Staphylococcus species from pet grooming salons.
CONCLUSIONS AND CLINICAL IMPORTANCE: Clipper blades, clipper handles and leashes are potential fomites for meticillin-resistant staphylococci in a grooming salon; increased disinfection practices for these items are indicated. A prospective, controlled, large-scale study is warranted to examine the effect of grooming salon hygiene practices on the isolation of meticillin-resistant staphylococci in salons. PMID: 31876006 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - December 25, 2019 Category: Veterinary Research Authors: Gould AP, Coyner KS, Trimmer AM, Weese JS, Budke CM Tags: Vet Dermatol Source Type: research

Nail caps: a practical solution for pruritic cats.
Abstract Feline non-flea hypersensitivity dermatitis (NFHD) is a common, chronic, relapsing, inflammatory, pruritic disease that can be challenging to treat. Feline cases with mild disease are usually managed quite well with palmitoylethanolamide, essential fatty acids supplementation along with intermittent use of topical, oral or injectable steroids during flares. PMID: 31869475 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - December 23, 2019 Category: Veterinary Research Authors: Maina E, Graziano L, Cornegliani L Tags: Vet Dermatol Source Type: research

Occult otitis media in dogs with chronic otitis externa - magnetic resonance imaging and association with otoscopic and cytological findings.
CONCLUSIONS AND CLINICAL IMPORTANCE: Occult OM is a not uncommon finding on MRI of dogs with chronic OE. A targeted MRI study ("bulla mini-scan") may be useful as part of the clinical investigations. PMID: 31858646 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - December 19, 2019 Category: Veterinary Research Authors: Lorek A, Dennis R, van Dijk J, Bannoehr J Tags: Vet Dermatol Source Type: research

Development and validation of a graphic 2D investigator's global assessment instrument for grading the overall severity of atopic dermatitis in dogs.
Abstract BACKGROUND: Clinical trials enrolling dogs with atopic dermatitis (AD) use validated instruments that aggregate the extent and severity of selected skin lesions; none of these provides a global assessment of the severity of all lesions. OBJECTIVES: To validate an Investigator Global Assessment (IGA) instrument to globally evaluate the severity of skin lesions in dogs with AD. ANIMALS: Forty dogs with AD. METHODS AND MATERIALS: A 2D graphic IGA (2D-IGA) instrument was created to subjectively score, with a single dot, the overall extent and severity of all canine AD lesions. This tool was tes...
Source: Veterinary Dermatology - December 12, 2019 Category: Veterinary Research Authors: High EJ, Olivry T Tags: Vet Dermatol Source Type: research

In vitro killing of canine strains of Staphylococcus pseudintermedius and Escherichia coli by cefazolin, cefovecin, doxycycline and pradofloxacin over a range of bacterial densities.
Abstract BACKGROUND: Bacterial densities likely fluctuate during infection and may exceed the bacterial density used in susceptibility testing. As such, investigation of bacterial killing by antibiotics over a range of varying bacterial densities may provide important differences between compounds and could impact drug selection for therapy. ANIMALS/MATERIALS: No animals were used. Bacterial strains collected from dogs with urinary tract infections were studied. HYPOTHESIS/OBJECTIVES: To measure killing of clinical isolates of S. pseudintermedius and E. coli by cefazolin, cefovecin, doxycycline and prado...
Source: Veterinary Dermatology - December 11, 2019 Category: Veterinary Research Authors: Blondeau JM, Fitch SD Tags: Vet Dermatol Source Type: research

An investigation of cross-reactivity between the poultry red mite and house dust and storage mites in dogs with contact with chickens infested with red mites.
CONCLUSIONS AND CLINICAL SIGNIFICANCE: Contact with PRM-infested chickens may lead to sensitization without allergy, independently from sensitization to house dust and storage mites. PMID: 31808208 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - December 5, 2019 Category: Veterinary Research Authors: Martins LML, Ventura ACN, Brazis P, Cerrato S Tags: Vet Dermatol Source Type: research

In vitro antimicrobial efficacy of two medical grade honey formulations against common high-risk meticillin-resistant staphylococci and Pseudomonas spp. pathogens.
Abstract BACKGROUND: Antimicrobial resistance is a problem in human and animal healthcare. Honey may be used for its wound healing properties and antimicrobial effects. OBJECTIVE: To investigate the antimicrobial activity of two commercially available medical grade honeys (MGHs) against Staphylococcus spp. and Pseudomonas spp. isolates. METHODS AND MATERIALS: Two formulations, MGH1 (40% w/v honey) and MGH2 (80% w/v Manuka honey), were tested in vitro for minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) against 11 Staphylococcus and 11 Pseudomonas isolates at low [1.5&...
Source: Veterinary Dermatology - December 5, 2019 Category: Veterinary Research Authors: Cremers N, Belas A, Santos Costa S, Couto I, de Rooster H, Pomba C Tags: Vet Dermatol Source Type: research

A small scale study to evaluate the efficacy of microneedling in the presence or absence of platelet-rich plasma in the treatment of post-clipping alopecia in dogs.
CONCLUSIONS AND CLINICAL IMPORTANCE: In dogs with post-clipping alopecia, MN + PRP appeared to induce more rapid hair regrowth than MN; however, overall results were visibly equivalent by six months regardless of method. Both MN and MN + PRP proved successful for treating post-clipping alopecia. PMID: 31797483 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - December 3, 2019 Category: Veterinary Research Authors: Diamond JC, Schick RO, Savage MY, Fadok VA Tags: Vet Dermatol Source Type: research

Sterile granulomatous dermatitis and lymphadenitis (juvenile cellulitis) in adult dogs: a retrospective analysis of 90 cases (2004-2018).
Abstract BACKGROUND: It has long been speculated that sterile granulomatous dermatitis and lymphadenitis (SGDL) occurs in adult dogs. However, only three published case reports exist. HYPOTHESIS/OBJECTIVES: To describe clinical presentation, identify breed predispositions, and assess treatment and outcomes of adult dogs with the histopathological diagnosis of SGDL. ANIMALS: Included are 90 dogs with biopsies submitted to a veterinary teaching hospital with a histopathological diagnosis consistent with SGDL, from 2004 to 2018, of which 35 had medical records available for review. METHODS: Data were a...
Source: Veterinary Dermatology - December 2, 2019 Category: Veterinary Research Authors: Inga A, Griffeth GC, Drobatz KJ, Goldschmidt KH, Mauldin EA Tags: Vet Dermatol Source Type: research

Abstracts of the 31st Annual Congress of the ECVD-ESVD, 26-29 September, 2019, Liverpool, UK.
Authors: PMID: 31749220 [PubMed] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - November 23, 2019 Category: Veterinary Research Tags: Vet Dermatol Source Type: research

Challenges and changes.
PMID: 31749221 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - November 23, 2019 Category: Veterinary Research Authors: Loeffler A Tags: Vet Dermatol Source Type: research

A case of mysterious black spots in a mixed breed dog.
PMID: 31749222 [PubMed - in process] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - November 23, 2019 Category: Veterinary Research Authors: Mauldin EA, Walsh E, Yager JA Tags: Vet Dermatol Source Type: research

Serum IgE and IgG responses to dietary antigens in dogs with and without cutaneous adverse food reactions.
CONCLUSION: This study demonstrated three protein bands and a poorly defined band predominantly recognized by sera from dogs with CAFR relative to non-CAFR dog sera. Almost all proteins were bound by IgG in all dogs, suggesting prior exposure to unreported foods. PMID: 31749195 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - November 20, 2019 Category: Veterinary Research Authors: Pucheu-Haston CM, Mougeot I Tags: Vet Dermatol Source Type: research

Efficacy study of a topical treatment with a plant extract with antibiofilm activities using an in vivo model of canine superficial pyoderma.
CONCLUSION: Topical application of W16P576 markedly reduced lesion development in this proof of principle study. Clinical trials are warranted to estimate benefits for dogs with naturally occurring pyoderma under field conditions. PMID: 31737969 [PubMed - as supplied by publisher] (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - November 18, 2019 Category: Veterinary Research Authors: Bäumer W, Jacobs M, Tamamoto-Mochizuki C Tags: Vet Dermatol Source Type: research

In vitro antibacterial activity of the manuka essential oil from Leptospermum scoparium combined with Tris-EDTA against Gram-negative bacterial isolates from dogs with otitis externa.
Abstract BACKGROUND: The increasing prevalence of antimicrobial resistance among bacteria in dogs with otitis externa has led to a need for novel therapeutic agents. HYPOTHESIS/OBJECTIVE: To examine the antibacterial effects of manuka oil combined with ethylenediaminetetraacetic acid-tromethamine (Tris-EDTA) against Gram-negative bacteria isolates from dogs with otitis externa. METHODS AND MATERIALS: A total of 53 clinical isolates including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae ssp. pneumoniae and Proteus mirabilis. Antimicrobial susceptibility was determined using disk diffusi...
Source: Veterinary Dermatology - November 15, 2019 Category: Veterinary Research Authors: Song SY, Hyun JE, Kang JH, Hwang CY Tags: Vet Dermatol Source Type: research