Use of High-Resolution Geospatial and Genomic Data to Characterize Recent Tuberculosis Transmission, Botswana
Emerg Infect Dis. 2023 May;29(5):977-987. doi: 10.3201/eid2905.220796.ABSTRACTCombining genomic and geospatial data can be useful for understanding Mycobacterium tuberculosis transmission in high-burden tuberculosis (TB) settings. We performed whole-genome sequencing on M. tuberculosis DNA extracted from sputum cultures from a population-based TB study conducted in Gaborone, Botswana, during 2012-2016. We determined spatial distribution of cases on the basis of shared genotypes among isolates. We considered clusters of isolates with ≤5 single-nucleotide polymorphisms identified by whole-genome sequencing to indicate rece...
Source: Emerging Infectious Diseases - April 25, 2023 Category: Infectious Diseases Authors: Chelsea R Baker Ivan Barilar Leonardo S de Araujo Anne W Rimoin Daniel M Parker Rosanna Boyd James L Tobias Patrick K Moonan Eleanor S Click Alyssa Finlay John E Oeltmann Vladimir N Minin Chawangwa Modongo Nicola M Zetola Stefan Niemann Sanghyuk S Shin Source Type: research
Viruses, Vol. 15, Pages 1051: Poxvirus Infections in Dairy Farms and Transhumance Cattle Herds in Nigeria
This study investigated suspected LSD outbreaks in organized and transhumance cattle herds in Nigeria in 2020. A total of 42 scab/skin biopsy samples were collected from 16 outbreaks of suspected LSD in five northern States of Nigeria. The samples were analyzed using a high-resolution multiplex melting (HRM) assay to differentiate poxviruses belonging to Orthopoxvirus, Capripoxvirus, and Parapoxvirus genera. LSDV was characterized using four gene segments, namely the RNA polymerase 30 kDa subunit (RPO30), G-protein-coupled receptor (GPCR), the extracellular enveloped virus (EEV) glycoprotein and CaPV homolog of the variola...
Source: Viruses - April 25, 2023 Category: Virology Authors: David Oludare Omoniwa Irene Kasindi Meki Caleb Ayuba Kudi Anthony Kojo Sackey Maryam Aminu Adeyinka Jeremy Adedeji Clement Adebajo Meseko Pam Dachung Luka Olayinka Oluwafemi Asala Jolly Amoche Adole Rebecca Bitiyong Atai Yakubu Joel Atuman Tirumala Bharan Tags: Article Source Type: research
Use of High-Resolution Geospatial and Genomic Data to Characterize Recent Tuberculosis Transmission, Botswana
Emerg Infect Dis. 2023 May;29(5):977-987. doi: 10.3201/eid2905.220796.ABSTRACTCombining genomic and geospatial data can be useful for understanding Mycobacterium tuberculosis transmission in high-burden tuberculosis (TB) settings. We performed whole-genome sequencing on M. tuberculosis DNA extracted from sputum cultures from a population-based TB study conducted in Gaborone, Botswana, during 2012-2016. We determined spatial distribution of cases on the basis of shared genotypes among isolates. We considered clusters of isolates with ≤5 single-nucleotide polymorphisms identified by whole-genome sequencing to indicate rece...
Source: Emerging Infectious Diseases - April 23, 2023 Category: Infectious Diseases Authors: Chelsea R Baker Ivan Barilar Leonardo S de Araujo Anne W Rimoin Daniel M Parker Rosanna Boyd James L Tobias Patrick K Moonan Eleanor S Click Alyssa Finlay John E Oeltmann Vladimir N Minin Chawangwa Modongo Nicola M Zetola Stefan Niemann Sanghyuk S Shin Source Type: research
Use of High-Resolution Geospatial and Genomic Data to Characterize Recent Tuberculosis Transmission, Botswana
Emerg Infect Dis. 2023 May;29(5):977-987. doi: 10.3201/eid2905.220796.ABSTRACTCombining genomic and geospatial data can be useful for understanding Mycobacterium tuberculosis transmission in high-burden tuberculosis (TB) settings. We performed whole-genome sequencing on M. tuberculosis DNA extracted from sputum cultures from a population-based TB study conducted in Gaborone, Botswana, during 2012-2016. We determined spatial distribution of cases on the basis of shared genotypes among isolates. We considered clusters of isolates with ≤5 single-nucleotide polymorphisms identified by whole-genome sequencing to indicate rece...
Source: Emerging Infectious Diseases - April 22, 2023 Category: Infectious Diseases Authors: Chelsea R Baker Ivan Barilar Leonardo S de Araujo Anne W Rimoin Daniel M Parker Rosanna Boyd James L Tobias Patrick K Moonan Eleanor S Click Alyssa Finlay John E Oeltmann Vladimir N Minin Chawangwa Modongo Nicola M Zetola Stefan Niemann Sanghyuk S Shin Source Type: research
Stunted Growth is Associated with Dyslipidemia in Young Adults with Perinatal HIV Infection
CONCLUSION: Dyslipidemia was common among perinatally HIV-infected youth and those with evidence of early nutritional deprivation were more likely to have elevated LDL-C.PMID:37071712 | DOI:10.1097/QAI.0000000000003209 (Source: Atherosclerosis)
Source: Atherosclerosis - April 18, 2023 Category: Cardiology Authors: Maemo Lesiapeto Justine Shults Mogakolodi Mmunyane Mogomotsi Matshaba Elizabeth D Lowenthal Source Type: research
Predictive factors of delayed viral clearance of asymptomatic omicron-related COVID-19 screened positive in cancer patients receiving active anti-cancer treatment
On November 26, 2021, the omicron (B.1.1.529) variant of SARS-CoV-2 was first identified in South Africa and Botswana as a highly transmissible variant of concern and was subsequently the cause of a pandemic surge in Europe, the USA, and Asia in late 2021 to early 2022 [1]. The fifth wave of the pandemic of COVID-19 in Hong Kong, primarily attributed to the omicron variant and subvariants (BA.2, BA.4, and BA.5) started in early January 2022 and resulted in widespread transmission at warp speed since then. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 15, 2023 Category: Infectious Diseases Authors: Victor Ho-Fun Lee, Sik-Kwan Chan, Yiu-Ho Tam, Tin-Ching Chau, Jasper Fuk Woo Chan, Sum-Yin Chan, Chun-Yat Ip, Horace Cheuk-Wai Choi, Sherry Chor-Yi Ng, Kwok Keung Yuen Source Type: research
Association Between Household Food Insecurity (Access) Scores, Poverty Indicators and Child Malnutrition in Botswana
Ecol Food Nutr. 2023 Apr 13:1-16. doi: 10.1080/03670244.2023.2202392. Online ahead of print.ABSTRACTIn Botswana the Household Food Insecurity Access Scale (HFIAS) has been used in studying the urban-poor, but less in rural settings high in poverty, child malnutrition (CM), and social protection beneficiaries. This cross-sectional study compared HFIAS scores, household poverty (HP) and CM in two rural districts: Bobirwa with moderate and Mabutsane with high poverty. Households (n = 872) with children under-five years participated. Most children (87.6%) experienced food insecurity. Mean HFIAS for all households was 11.0 ± 8...
Source: Ecology of Food and Nutrition - April 14, 2023 Category: Nutrition Authors: Maria Sennye Nnyepi Matsapa Phegelo Tshepiso Galase Ramolefhe-Mutumwa David Mmopelwa Source Type: research
