The impact of free antiretroviral therapy for pregnant non-citizens and their infants in Botswana
CONCLUSIONS: Following the expansion of free antiretroviral therapy to non-citizens, gaps narrowed in ANC and antiretroviral therapy use in pregnancy between citizens and non-citizens living with HIV. Disparities in adverse birth outcomes were no longer observed.PMID:37885157 | DOI:10.1002/jia2.26161 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - October 27, 2023 Category: Infectious Diseases Authors: Christina Fennell Daniel Escudero Rebecca Zash Modiegi Diseko Gloria Mayondi Judith Mabuta Tumalano Sekoto Tendani Gaolathe Mompati Mmalane Shahin Lockman Joseph Makhema Roger Shapiro Source Type: research

The impact of free antiretroviral therapy for pregnant non-citizens and their infants in Botswana
CONCLUSIONS: Following the expansion of free antiretroviral therapy to non-citizens, gaps narrowed in ANC and antiretroviral therapy use in pregnancy between citizens and non-citizens living with HIV. Disparities in adverse birth outcomes were no longer observed.PMID:37885157 | PMC:PMC10603275 | DOI:10.1002/jia2.26161 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - October 27, 2023 Category: Infectious Diseases Authors: Christina Fennell Daniel Escudero Rebecca Zash Modiegi Diseko Gloria Mayondi Judith Mabuta Tumalano Sekoto Tendani Gaolathe Mompati Mmalane Shahin Lockman Joseph Makhema Roger Shapiro Source Type: research

Tuberculosis Variant with Rifampin Resistance Undetectable by Xpert MTB/RIF, Botswana
We report transmission of a pre-extensively drug-resistant variant in Botswana that went undetected by GeneXpert. The public health impact of misdiagnosis emphasizes the need for comprehensive molecular testing to identify resistance and guide treatment.PMID:37877680 | DOI:10.3201/eid2911.230987 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 25, 2023 Category: Infectious Diseases Authors: Chawangwa Modongo Ivan Barilar Qiao Wang Tuduetso Molefi Topo Makhondo Stefan Niemann Sanghyuk S Shin Source Type: research

Tuberculosis Variant with Rifampin Resistance Undetectable by Xpert MTB/RIF, Botswana
We report transmission of a pre-extensively drug-resistant variant in Botswana that went undetected by GeneXpert. The public health impact of misdiagnosis emphasizes the need for comprehensive molecular testing to identify resistance and guide treatment.PMID:37877680 | DOI:10.3201/eid2911.230987 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 25, 2023 Category: Infectious Diseases Authors: Chawangwa Modongo Ivan Barilar Qiao Wang Tuduetso Molefi Topo Makhondo Stefan Niemann Sanghyuk S Shin Source Type: research

Stroke management and outcomes in low-income and lower-middle-income countries: a meta-analysis of 8535 patients
CONCLUSIONS: A severe healthcare disparity is present in low-income and lower-middle-income countries, where there is delayed diagnosis of strokes and increased rates of poor clinical outcomes for these patients.PMID:37856884 | DOI:10.3171/2023.2.JNS222807 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 19, 2023 Category: Neurosurgery Authors: Alexander O Aguirre James L Rogers Taylor Reardon Nathan A Shlobin Alexander M Ballatori Nolan J Brown Julian Gendreau Shane Shahrestani Source Type: research

Stroke management and outcomes in low-income and lower-middle-income countries: a meta-analysis of 8535 patients
CONCLUSIONS: A severe healthcare disparity is present in low-income and lower-middle-income countries, where there is delayed diagnosis of strokes and increased rates of poor clinical outcomes for these patients.PMID:37856884 | DOI:10.3171/2023.2.JNS222807 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 19, 2023 Category: Neurosurgery Authors: Alexander O Aguirre James L Rogers Taylor Reardon Nathan A Shlobin Alexander M Ballatori Nolan J Brown Julian Gendreau Shane Shahrestani Source Type: research

No increased in utero and peripartum HIV acquisition risk in HIV-exposed preterm infants
Conclusion: There was no observed increase of in utero and peripartum HIV acquisition among infants born preterm following foetal exposure to HIV compared to those born at term. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 19, 2023 Category: African Health Authors: Globahan Ajibola Source Type: research

Pollution index of soils along and against the wind direction within a 40  km distance of Morupule Fly Ash Dumpsite, Botswana
AbstractArsenic, chromium, copper, lead, and zinc concentrations were measured in the leeward and windward directions within 40  km of the Morupule power station to assess the long-term effects of fly ash deposition on the hazardous metal contamination of soils. Based on the quantities of these metals in the soil, the contamination factor, pollution load index, and potential ecological risk index were calculated to determin e the potential of these metals will harm the ecosystem and human health. The results showed that areas (0.1–2 km) nearer to the dumpsite, especially in the leeward direction had higher contaminatio...
Source: Environmental Quality Management - October 18, 2023 Category: Environmental Health Authors: Katumelo Gajaje, Omphile Monnakgotla, Venecio U. Ultra Jr., Trust Manyiwa Tags: RESEARCH ARTICLE Source Type: research

A simple and rapid external standard calibration HPLC method for determination of lumefantrine in dried blood spot samples from malaria patients in Botswana
In conclusion, data suggest that the method is suitable for the determination of trace Lum in biofluids and can also be used for therapeutic drug monitoring and pharmacokinetic profiling.PMID:37845823 | DOI:10.1002/bmc.5762 (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - October 17, 2023 Category: Biomedical Science Authors: Blondie O Brooks Giacomo Maria Paganotti Amos Massele Enoch Sepako Paul Adiukwu Kwenga Festus Sichilongo Source Type: research

A simple and rapid external standard calibration HPLC method for determination of lumefantrine in dried blood spot samples from malaria patients in Botswana
In conclusion, data suggest that the method is suitable for the determination of trace Lum in biofluids and can also be used for therapeutic drug monitoring and pharmacokinetic profiling.PMID:37845823 | DOI:10.1002/bmc.5762 (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - October 17, 2023 Category: Biomedical Science Authors: Blondie O Brooks Giacomo Maria Paganotti Amos Massele Enoch Sepako Paul Adiukwu Kwenga Festus Sichilongo Source Type: research

Tuberculosis Variant with Rifampin Resistance Undetectable by Xpert MTB/RIF, Botswana
C. Modongo et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - October 16, 2023 Category: Infectious Diseases Source Type: research

Accessing HIV services in Botswana: perspectives of men who have sex with men and other stakeholders
CONCLUSION: Discrimination against MSM undermines the ability of HIV interventions to address MSM sexual health needs. The findings indicate the importance of enabling MSM to overcome discrimination to seek HIV services. Also, there is a need to further explore discrimination against MSM by service providers within the healthcare settings and ways to improve their understanding of male same-sex practices.PMID:37830348 | DOI:10.1080/16549716.2023.2262197 (Source: Global Health Action)
Source: Global Health Action - October 13, 2023 Category: International Medicine & Public Health Authors: Kgosiekae Maxwell Matlapeng Gbotemi Bukola Babatunde Netsai Bianca Gwelo Olagoke Akintola Source Type: research