Viruses, Vol. 15, Pages 1383: The Molecular Epidemiology of Clade 2.3.4.4B H5N1 High Pathogenicity Avian Influenza in Southern Africa, 2021 & ndash;2022
In this study, the complete or partial genomes of 117 viruses from the SA outbreaks in 2021–2022 were analyzed to decipher the sub-regional spread of the disease. Our analysis showed that seven H5N1 sub-genotypes were associated with the initial outbreaks, but by late 2022 only two sub-genotypes still circulated. Furthermore, SA poultry was not the source of Lesotho’s outbreaks, and the latter was most likely an introduction from wild birds. Similarly, SA and Botswana’s outbreaks in 2021 were unrelated, but viruses of Botswana’s unique sub-genotype were introduced int...
Source: Viruses - June 16, 2023 Category: Virology Authors: Celia Abolnik Thandeka Phiri Belinda Peyrot Renee de Beer Albert Snyman David Roberts Katrin Ludynia Frances Jordaan Michele Maartens Zehaad Ismail Christine Strydom Gerbrand van der Zel Jade Anthony Nadine Daniell Liesl De Boni John Grewar Adriaan Olivie Tags: Article Source Type: research
Co-trimoxazole prophylaxis for children who are HIV-exposed and uninfected: a systematic review
CONCLUSIONS: In low-mortality settings with few HIV transmissions and well-performing early infant diagnosis and treatment programmes, universal co-trimoxazole may not be required.PMID:37292018 | DOI:10.1002/jia2.26079 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - June 9, 2023 Category: Infectious Diseases Authors: Catherine J Wedderburn Ceri Evans Amy L Slogrove Andrea M Rehman Diana M Gibb Andrew J Prendergast Martina Penazzato Source Type: research
Co-trimoxazole prophylaxis for children who are HIV-exposed and uninfected: a systematic review
CONCLUSIONS: In low-mortality settings with few HIV transmissions and well-performing early infant diagnosis and treatment programmes, universal co-trimoxazole may not be required.PMID:37292018 | PMC:PMC10251133 | DOI:10.1002/jia2.26079 (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - June 9, 2023 Category: Infectious Diseases Authors: Catherine J Wedderburn Ceri Evans Amy L Slogrove Andrea M Rehman Diana M Gibb Andrew J Prendergast Martina Penazzato Source Type: research
Feeding back of individual genetic results in Botswana: mapping opportunities and challenges
We explored the views of Botswana stakeholders involved in developing, implementing and applying ethical standards for return of individual study results from genomic research. This allowed for mapping opportu... (Source: BMC Medical Ethics)
Source: BMC Medical Ethics - June 3, 2023 Category: Medical Ethics Authors: Mary Kasule, Mogomotsi Matshaba, Ambroise Wonkam and Jantina de Vries Tags: Research Source Type: research
