Viruses, Vol. 16, Pages 592: High Prevalence of Hepatitis B Virus Drug Resistance Mutations to Lamivudine among People with HIV/HBV Coinfection in Rural and Peri-Urban Communities in Botswana
Conclusions: The high prevalence of lamivudine RAMs discourages the use of ART regimens with 3TC as the only HBV-active drug in people with HIV/HBV. (Source: Viruses)
Source: Viruses - April 11, 2024 Category: Virology Authors: Bonolo B. Phinius Motswedi Anderson Irene Gobe Margaret Mokomane Wonderful T. Choga Basetsana Phakedi Tsholofelo Ratsoma Gorata Mpebe Joseph Makhema Roger Shapiro Shahin Lockman Rosemary Musonda Sikhulile Moyo Simani Gaseitsiwe Tags: Article Source Type: research
GSE263394 Dolutegravir induces FOLR1 expression during brain organoid development.
Contributors : Daniel Kraushaar ; Carlo Donato Caiaffa ; Robert M CabreraSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe brain and spinal cord are formed during neurulation, a developmental process that occurs during the first month of pregnancy and can be modified by low serum levels of folic acid (FA), environmental factors, or genetic predispositions. In 2018, data from a surveillance study in Botswana, a country with one of the highest incidences of human immunodeficiency virus (HIV) and lacking mandatory food folate fortification programs, revealed an increased risk of neur...
Source: GEO: Gene Expression Omnibus - April 10, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Adult surgical admissions at a Botswana tertiary teaching hospital - spectrum, comorbidity profile, and outcomes
CONCLUSION: Contributions of emergency and elective admissions were even. A higher burden of diseases was found in gastroenterology. The higher mortalities associated with hypertension, diabetes, and CD4 count < 200 warrant further study.PMID:38568128 (Source: South African Journal of Surgery)
Source: South African Journal of Surgery - April 3, 2024 Category: Surgery Authors: A G Bedada M J Mpapho S G Hamda Source Type: research
