Influence of pH and temperature on the performance and microbial community during the production of medium-chain carboxylic acids using winery effluents as substrate
This study presents novel insights into the bioconversion mechanisms of medium-chain carboxylic acids by correlating fermentation and chain elongation kinetic profiles with the study of microbial communities at different pH (5 to 7) conditions and temperatures (30 to 40 °C). It was found that high productivities of MCCA were obtained using a native culture and winery effluents as a natural substrate. Minor pH variations significantly affected the metabolic pathway of the microorganisms for MCCA production. The maximal productivities of hexanoic (715 mg/L/d) and octanoic (350 mg/L/d) acids were found at pH 6 and 35 °C. Re...
Source: Environmental Science and Pollution Research International - April 1, 2024 Category: Environmental Health Authors: Sharon B Villegas-Rodr íguez Jorge Arreola-Vargas Germ án Buitrón Source Type: research

Exploring the prebiotic potential of hydrolyzed fucoidan fermented in vitro with human fecal inocula: Impact on microbiota and metabolome
Int J Biol Macromol. 2024 Mar 29:131202. doi: 10.1016/j.ijbiomac.2024.131202. Online ahead of print.ABSTRACTFucoidan is widely applied in food and pharmaceutical industry for the promising bioactivities. Low-molecular weight hydrolyzed fucoidan has gained attention for its beneficial health effects. Here, the modulation on microbiome and metabolome features of fucoidan and its acidolyzed derivatives (HMAF, 1.5-20 kDa; LMAF, <1.5 kDa) were investigated through human fecal cultures. Fucose is the main monosaccharide component in fucoidan and LMAF, while HMAF contains abundant glucuronic acid. LMAF fermentation resulted in...
Source: International Journal of Biological Macromolecules - March 31, 2024 Category: Biochemistry Authors: Xinru Huang Shaoping Nie Xiaodan Fu Shihao Nan Xinmiao Ren Rong Li Source Type: research

Exploring the prebiotic potential of hydrolyzed fucoidan fermented in vitro with human fecal inocula: Impact on microbiota and metabolome
Int J Biol Macromol. 2024 Mar 29:131202. doi: 10.1016/j.ijbiomac.2024.131202. Online ahead of print.ABSTRACTFucoidan is widely applied in food and pharmaceutical industry for the promising bioactivities. Low-molecular weight hydrolyzed fucoidan has gained attention for its beneficial health effects. Here, the modulation on microbiome and metabolome features of fucoidan and its acidolyzed derivatives (HMAF, 1.5-20 kDa; LMAF, <1.5 kDa) were investigated through human fecal cultures. Fucose is the main monosaccharide component in fucoidan and LMAF, while HMAF contains abundant glucuronic acid. LMAF fermentation resulted in...
Source: International Journal of Biological Macromolecules - March 31, 2024 Category: Biochemistry Authors: Xinru Huang Shaoping Nie Xiaodan Fu Shihao Nan Xinmiao Ren Rong Li Source Type: research

Colitis reduces active social engagement in mice and is ameliorated by supplementation with human microbiota members
Nat Commun. 2024 Mar 30;15(1):2769. doi: 10.1038/s41467-024-46733-7.ABSTRACTMultiple neurological disorders are associated with gastrointestinal (GI) symptoms, including autism spectrum disorder (ASD). However, it is unclear whether GI distress itself can modify aspects of behavior. Here, we show that mice that experience repeated colitis have impaired active social engagement, as measured by interactions with a foreign mouse, even though signs of colitis were no longer present. We then tested the hypothesis that individuals with ASD harbor a microbiota that might differentially influence GI health by performing microbiota...
Source: Cancer Control - March 30, 2024 Category: Cancer & Oncology Authors: D Garrett Brown Michaela Murphy Roberto Cadeddu Rickesha Bell Allison Weis Tyson Chiaro Kendra Klag Jubel Morgan Hilary Coon W Zac Stephens Marco Bortolato June L Round Source Type: research

Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research

Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research

Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research

Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research

Exploring the diversity of vaginal microbiota between healthy women and cervical cancer patients in India
Conclusion. Differences in the vaginal microbiome between healthy and ICC women could help in the early prediction of cervical cancer risk and thus in designing prevention strategies.PMID:38546452 | DOI:10.1099/jmm.0.001819 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - March 28, 2024 Category: Microbiology Authors: Ashwini Kamble Shilpa Naik Manju Talathi Deepali Jadhav Meena Sakharkar Jian Yang Om Prakash Ruchika Kaul-Ghanekar Source Type: research

Disruptions of Gut Microbiota are Associated with Cognitive Deficit of Preclinical Alzheimer's Disease: A Cross-Sectional Study
CONCLUSION: The gut microbiota in patients with preclinical AD has significantly changed in terms of composition and richness. Correlations have been discovered between changes in characteristic species and cognitive performances. Gut microbiota alterations have shown promise in affecting AD pathology and cognitive deficit.PMID:38529601 | DOI:10.2174/0115672050303878240319054149 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 26, 2024 Category: Neurology Authors: Binbin Yu Guomeng Wan Shupeng Cheng Pengcheng Wen Xi Yang Jiahuan Li Huifang Tian Yaxin Gao Qian Zhong Jin Liu Jianan Li Yi Zhu Source Type: research

Disruptions of Gut Microbiota are Associated with Cognitive Deficit of Preclinical Alzheimer's Disease: A Cross-Sectional Study
CONCLUSION: The gut microbiota in patients with preclinical AD has significantly changed in terms of composition and richness. Correlations have been discovered between changes in characteristic species and cognitive performances. Gut microbiota alterations have shown promise in affecting AD pathology and cognitive deficit.PMID:38529601 | DOI:10.2174/0115672050303878240319054149 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 26, 2024 Category: Neurology Authors: Binbin Yu Guomeng Wan Shupeng Cheng Pengcheng Wen Xi Yang Jiahuan Li Huifang Tian Yaxin Gao Qian Zhong Jin Liu Jianan Li Yi Zhu Source Type: research

Disruptions of Gut Microbiota are Associated with Cognitive Deficit of Preclinical Alzheimer's Disease: A Cross-Sectional Study
CONCLUSION: The gut microbiota in patients with preclinical AD has significantly changed in terms of composition and richness. Correlations have been discovered between changes in characteristic species and cognitive performances. Gut microbiota alterations have shown promise in affecting AD pathology and cognitive deficit.PMID:38529601 | DOI:10.2174/0115672050303878240319054149 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 26, 2024 Category: Neurology Authors: Binbin Yu Guomeng Wan Shupeng Cheng Pengcheng Wen Xi Yang Jiahuan Li Huifang Tian Yaxin Gao Qian Zhong Jin Liu Jianan Li Yi Zhu Source Type: research

Disruptions of Gut Microbiota are Associated with Cognitive Deficit of Preclinical Alzheimer's Disease: A Cross-Sectional Study
CONCLUSION: The gut microbiota in patients with preclinical AD has significantly changed in terms of composition and richness. Correlations have been discovered between changes in characteristic species and cognitive performances. Gut microbiota alterations have shown promise in affecting AD pathology and cognitive deficit.PMID:38529601 | DOI:10.2174/0115672050303878240319054149 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 26, 2024 Category: Neurology Authors: Binbin Yu Guomeng Wan Shupeng Cheng Pengcheng Wen Xi Yang Jiahuan Li Huifang Tian Yaxin Gao Qian Zhong Jin Liu Jianan Li Yi Zhu Source Type: research

Disruptions of Gut Microbiota are Associated with Cognitive Deficit of Preclinical Alzheimer's Disease: A Cross-Sectional Study
CONCLUSION: The gut microbiota in patients with preclinical AD has significantly changed in terms of composition and richness. Correlations have been discovered between changes in characteristic species and cognitive performances. Gut microbiota alterations have shown promise in affecting AD pathology and cognitive deficit.PMID:38529601 | DOI:10.2174/0115672050303878240319054149 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 26, 2024 Category: Neurology Authors: Binbin Yu Guomeng Wan Shupeng Cheng Pengcheng Wen Xi Yang Jiahuan Li Huifang Tian Yaxin Gao Qian Zhong Jin Liu Jianan Li Yi Zhu Source Type: research

Disruptions of Gut Microbiota are Associated with Cognitive Deficit of Preclinical Alzheimer's Disease: A Cross-Sectional Study
CONCLUSION: The gut microbiota in patients with preclinical AD has significantly changed in terms of composition and richness. Correlations have been discovered between changes in characteristic species and cognitive performances. Gut microbiota alterations have shown promise in affecting AD pathology and cognitive deficit.PMID:38529601 | DOI:10.2174/0115672050303878240319054149 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - March 26, 2024 Category: Neurology Authors: Binbin Yu Guomeng Wan Shupeng Cheng Pengcheng Wen Xi Yang Jiahuan Li Huifang Tian Yaxin Gao Qian Zhong Jin Liu Jianan Li Yi Zhu Source Type: research