Effects of soy milk consumption on gut microbiota, inflammatory markers, and disease severity in patients with ulcerative colitis: a study protocol for a randomized clinical trial
This study is a randomized clinical trial, in which thirty patients with mild to moderate severity of UC will be randomly allocated to receive either 250  mL/day soy milk plus routine treatments (n = 15) or only routine treatments (n = 15) for 4 weeks. Assessment of anthropometric measures and biochemical indicators including serum concentrations of high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interferon gamma (IFN-γ) will be done at the study baseline and end of trial. In addition, the quantity of butyrate-producing bacteria includingClostridiu...
Source: Trials - June 22, 2020 Category: Research Source Type: clinical trials

A randomized controlled trial investigating the effect of a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols on the intestinal microbiome and inflammation in patients with ulcerative colitis: study protocol for a randomized controlled trial
This study is a randomized clinical trial. Thirty patients with mild to moderate ulcerative colitis will be randomly allocated to receive a low FODMAP diet (n = 15) or to continue their usual diet as control (n = 15), for 4 weeks. The quantity of intestinal microbiota including Clostridium cluster IV,Faecalibacterium prausnitzii, Rosburia spp., Lactobacillus spp., Bifidobacteria spp.,Akkermansia muciniphila,Bacteroides fragilis, and Ruminococcus spp., and theFirmicutes toBacteroidetes ratio and calprotectin and lactoferrin levels will be explored in fecal samples from patients. In addition, anthropometric measure...
Source: Trials - February 17, 2020 Category: Research Source Type: clinical trials

Prevention of Preterm Infection by Autologous Umbilical Cord Blood Mononuclear Cells Therapy
Conditions:   Infection, Bacteroides;   Neonates Premature;   Neonatal Death Interventions:   Other: Autologous Umbilical Cord Blood Mononuclear Cells Therapy;   Drug: 0.9% Sodium Chloride Sponsor:   Guangdong Women and Children's Hospital and Health Institute Not yet recruiting - verified December 2016 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 3, 2016 Category: Research Source Type: clinical trials