Adalimumab/Amoxicillin/clavulanic-acid
(Source: Reactions Weekly)
Source: Reactions Weekly - February 1, 2024 Category: Drugs & Pharmacology Source Type: research
Outcomes of Single Dose Oral Amoxicillin Challenges in a Pediatric Outpatient Allergy Clinic
We examined the outcomes of single dose oral amoxicillin challenges performed at a single center. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Laura Wang, Allison Hicks, Maureen Bauer, Kirstin Carel Source Type: research
Frequency of changes in immunoglobulins, B-cells, and B-regulatory cells in patients with allergic reactions to amoxicillin over time after the acute reaction.
Amoxicillin (AX) immediate allergic reactions have been increasing over last decades due to its higher prescription. Although AX-specific immunoglobulin E (sIgE) is the most important immunoglobulin involved in allergic reactions, others may also play an important role during both acute and recovery phases. Our main goal was to analyze the frequency of different serum-AX-specific immunoglobulins, blood switched B cells with different isotypes, and B regulatory cells at different time-points after the acute reaction. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Rub én Fernández-Santamaría, Maria Salas Cassinello, Gador Bogas Herrera, Cristobalina Mayorga, Maria Torres Jaen, Cezmi Akdis, Mubeccel Akdis, Willem Van de Veen Source Type: research
Prospective study to analyze the synergistic effect of amoxicillin and lipopolysaccharide in basophil activation to improve the diagnosis of IgE-mediated hypersensitivity reactions to amoxicillin
Amoxicillin (AX) is the betalactam (BL) most frequently involved in IgE-mediated reactions. Basophil activation test (BAT) is a safe complementary in vitro tool for IgE-mediated reactions; however, its sensitivity is sub-optimal. This fact could be related to the requirement of including pathogen-derived molecules, as shown by a preliminary case-control study evaluating the synergistic effect of lipopolysaccharide (LPS) and AX. Our aim was to perform a prospective real-life study to analyze if the inclusion of LPS in BAT could reproduce the acute phase of BL-allergic reactions and therefore increase its sensitivity. (Sourc...
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Jose Cespedes, Rub én Fernández-Santamaría, Reyes García-Otón, Silvia Calvo-Serrano, Gádor Bogas, Leonardo Tomei, Miriam Monge, Maria Salas, Inmaculada Dona Diaz, Marina Labella, Cristobalina Mayorga, Tahia Fernández, María Torres, Adriana Ariza V Source Type: research
Efficacy and Safety of Vonoprazan-Amoxicillin Dual Regimen With Varying Dose and Duration for Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Study
This study aims to investigate vonoprazan with varying amoxicillin dose and duration. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 1, 2024 Category: Gastroenterology Authors: Xiang Peng, Jia-Yin Yao, Yu-qian Ma, Guo-hua Li, Huang-wei Chen, Yu Wan, Dong-sheng Liang, Min Zhang, Min Zhi Source Type: research
Rapid screening of bacteriostatic and bactericidal antimicrobial agents against Escherichia coli by combining machine learning (artificial intelligence) and UV-VIS spectroscopy
Analyst, 2024, Advance Article DOI: 10.1039/D3AN01608K, PaperR. Orrell-Trigg, M. Awad, S. Gangadoo, S. Cheeseman, Z. L. Shaw, V. K. Truong, D. Cozzolino, J. Chapman A standard UV-Vis spectrophotometer, chemometrics, and machine learning algorithms enables faster identification of bacteriostatic and bactericidal mechanisms. Compared to traditional methods, this approach accelerates the evaluation of tetracycline and amoxicillin onE. coli. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - January 31, 2024 Category: Chemistry Authors: R. Orrell-Trigg Source Type: research
Neck Space Infection: A Retrospective Study of 40 Cases at a Tertiary Care Center in Sibu, Malaysia
This study is intended to explore the relationship of etiologies of neck space infection (NSI) and its prevalent microorganisms of NSI and to compare the treatments and its clinical outcomes with other studies. A retrospective study of 1 year duration from April 2022–April 2023 at ENT department Hospital Sibu includes total 40 NSI patients. 30 male and 10 female patients, with a male-to-female ratio of 3 were studied, with a mean age of 35.07 (± 18.25) years. Diabetes mellitus still constituted a high risk factor (27.3%), whi le patients with biohazard status (Hepatitis B and C) contributes 15.1%. There were 18 case...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - January 27, 2024 Category: ENT & OMF Source Type: research
Informal sale of antibiotics in Guatemalan convenience stores before and after implementation of federal antibiotic dispensing legislation
CONCLUSIONS: Antibiotics remain widely available in convenience stores consistent with no significant change in the informal sector after implementation of prescription requirements for pharmacies. Importantly, effects from regulatory change could have been masked by potential changes in antibiotic use during the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic.PMID:38273410 | PMC:PMC10809560 | DOI:10.1186/s40360-023-00720-8 (Source: BMC Pharmacology and Toxicology)
Source: BMC Pharmacology and Toxicology - January 25, 2024 Category: Drugs & Pharmacology Authors: N Rojop P Moreno L Grajeda J Romero L Reynoso E Mu ñoz G H Palmer C Cord ón-Rosales D R Call B M Ramay Source Type: research
Exploratory Pilot Studies to Demonstrate Mechanisms of Preventing Antibiotic-Associated Diarrhea and the Role for Probiotics
Ann Fam Med. 2024 Nov 1;21(Suppl 3). doi: 10.1370/afm.22.s1.4766.ABSTRACTContext: Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. One of the most common indications for probiotic treatment is the prevention of antibiotic-associated diarrhea (AAD). Unfortunately, many probiotic products used for AAD are not supported by rigorous independent research, and often results in non-evidence-based usage. Additionally, it is not clear when is the most appropriate time to take a probiotic when on an antibiotic course. Objectives: The primary aim is to determine the ...
Source: Annals of Family Medicine - January 25, 2024 Category: Primary Care Authors: Daniel Merenstein Tina Tan Keisha Herbin Smith Source Type: research
Incidence of catheter-associated urinary tract infections by Gram-negative bacilli and their ESBL and carbapenemase production in specialized hospitals of Bahir Dar, northwest Ethiopia
ConclusionsIncidence of CAUTI with Gram-negative bacilli is high. As most of the GNB isolates are MDR and showed a super high rate of resistance to amoxicillin-clavulanic and third-generation cephalosporins, empirical treatment with these substances is virtually ineffective in patients with suspected GNB infection in Ethiopia. The expression of ESBL and carbapenemase among GNB isolates is also a concern. Therefore, improved infection prevention and control measures, careful use of catheters and third generation of cephalosporins are needed to improve patient outcomes and reduce the burden of CAUTIs and the spreading of ant...
Source: Antimicrobial Resistance and Infection Control - January 25, 2024 Category: Infectious Diseases Source Type: research
A New Case of Fournier's Gangrene Caused by Actinotignum schaalii
In conclusion, it is thought that a significant proportion of A.schaalii infections may be overlooked due to the difficulty in growth and identification. Increasing the diagnostic power of clinical microbiology laboratories for poorly identified bacteria and renewing the databases of commercial identification systems are important for the early and accurate diagnosis and treatment of serious infections that may occur with such agents.PMID:38263943 | DOI:10.5578/mb.20249908 (Source: Mikrobiyoloji Bulteni)
Source: Mikrobiyoloji Bulteni - January 24, 2024 Category: Microbiology Authors: Hanife Tutan Cemil Kutsal Özlem Gül Elif Seren Tanr ıverdi Ay şe Barış Mehmet Emin Bulut Elif Akta ş Source Type: research
