Frequency of changes in immunoglobulins, B-cells, and B-regulatory cells in patients with allergic reactions to amoxicillin over time after the acute reaction.
Amoxicillin (AX) immediate allergic reactions have been increasing over last decades due to its higher prescription. Although AX-specific immunoglobulin E (sIgE) is the most important immunoglobulin involved in allergic reactions, others may also play an important role during both acute and recovery phases. Our main goal was to analyze the frequency of different serum-AX-specific immunoglobulins, blood switched B cells with different isotypes, and B regulatory cells at different time-points after the acute reaction.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Rub én Fernández-Santamaría, Maria Salas Cassinello, Gador Bogas Herrera, Cristobalina Mayorga, Maria Torres Jaen, Cezmi Akdis, Mubeccel Akdis, Willem Van de Veen Source Type: research