Optimized sequential therapy < em > vs < /em > 10- and 14-d concomitant therapy for eradicating < em > Helicobacter pylori < /em > : A randomized clinical trial
CONCLUSION: The optimized 14-d sequential therapy is a safe and effective alternative. Its eradication rate is comparable to that of the 14-d concomitant therapy while causing fewer AEs and allowing a gain in terms of cost.PMID:38463026 | PMC:PMC10921140 | DOI:10.3748/wjg.v30.i6.556 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Hassan Seddik Jihane Benass Sanaa Berrag Asmae Sair Reda Berraida Hanae Boutallaka Source Type: research

Optimized sequential therapy < em > vs < /em > 10- and 14-d concomitant therapy for eradicating < em > Helicobacter pylori < /em > : A randomized clinical trial
CONCLUSION: The optimized 14-d sequential therapy is a safe and effective alternative. Its eradication rate is comparable to that of the 14-d concomitant therapy while causing fewer AEs and allowing a gain in terms of cost.PMID:38463026 | PMC:PMC10921140 | DOI:10.3748/wjg.v30.i6.556 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - March 11, 2024 Category: Gastroenterology Authors: Hassan Seddik Jihane Benass Sanaa Berrag Asmae Sair Reda Berraida Hanae Boutallaka Source Type: research

Optimized sequential therapy < em > vs < /em > 10- and 14-d concomitant therapy for eradicating < em > Helicobacter pylori < /em > : A randomized clinical trial
CONCLUSION: The optimized 14-d sequential therapy is a safe and effective alternative. Its eradication rate is comparable to that of the 14-d concomitant therapy while causing fewer AEs and allowing a gain in terms of cost.PMID:38463026 | PMC:PMC10921140 | DOI:10.3748/wjg.v30.i6.556 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 11, 2024 Category: Gastroenterology Authors: Hassan Seddik Jihane Benass Sanaa Berrag Asmae Sair Reda Berraida Hanae Boutallaka Source Type: research

Optimized sequential therapy < em > vs < /em > 10- and 14-d concomitant therapy for eradicating < em > Helicobacter pylori < /em > : A randomized clinical trial
CONCLUSION: The optimized 14-d sequential therapy is a safe and effective alternative. Its eradication rate is comparable to that of the 14-d concomitant therapy while causing fewer AEs and allowing a gain in terms of cost.PMID:38463026 | PMC:PMC10921140 | DOI:10.3748/wjg.v30.i6.556 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - March 11, 2024 Category: Gastroenterology Authors: Hassan Seddik Jihane Benass Sanaa Berrag Asmae Sair Reda Berraida Hanae Boutallaka Source Type: research

Multisite primary care led amoxicillin challenge pathway to safely remove penicillin allergy label
ConclusionsOur study demonstrates a pediatric specific screener and pathway for pediatric providers to safely remove penicillin allergy labels following latest allergy practice parameters. (Source: Drugs and Therapy Perspectives)
Source: Drugs and Therapy Perspectives - March 10, 2024 Category: Drugs & Pharmacology Source Type: research

Bismuth add-on improves the efficacy of 2-week tegoprazan-based triple therapy for first-line Helicobacter pylori eradication: a real-world evidence study
CONCLUSIONS: The bismuth add-on increased the first-line H. pylori eradication rate of 2-week TPZ-based triple therapy.PMID:38459869 | DOI:10.1080/14787210.2024.2329251 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - March 9, 2024 Category: Infectious Diseases Authors: Jun-Hyung Cho Source Type: research

The multicenter real-world report of the efficacies of 14-day esomeprazole-based and rabeprazole-based high-dose dual therapy in first-line Helicobacter pylori eradication in Taiwan
CONCLUSIONS: Esomeprazole-based HDDT achieved over 90% eradication rates but rabeprazole-based HDDT, which failed.PMID:38461114 | DOI:10.1016/j.jmii.2024.02.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 9, 2024 Category: Microbiology Authors: Wei-Chen Tai I-Ting Wu Hsin-Ming Wang Pao-Yuan Huang Chih-Chien Yao Cheng-Kun Wu Shih-Cheng Yang Chih-Ming Liang Pin-I Hsu Seng-Kee Chuah Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

Bismuth add-on improves the efficacy of 2-week tegoprazan-based triple therapy for first-line Helicobacter pylori eradication: a real-world evidence study
CONCLUSIONS: The bismuth add-on increased the first-line H. pylori eradication rate of 2-week TPZ-based triple therapy.PMID:38459869 | DOI:10.1080/14787210.2024.2329251 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - March 9, 2024 Category: Infectious Diseases Authors: Jun-Hyung Cho Source Type: research

The multicenter real-world report of the efficacies of 14-day esomeprazole-based and rabeprazole-based high-dose dual therapy in first-line Helicobacter pylori eradication in Taiwan
CONCLUSIONS: Esomeprazole-based HDDT achieved over 90% eradication rates but rabeprazole-based HDDT, which failed.PMID:38461114 | DOI:10.1016/j.jmii.2024.02.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 9, 2024 Category: Microbiology Authors: Wei-Chen Tai I-Ting Wu Hsin-Ming Wang Pao-Yuan Huang Chih-Chien Yao Cheng-Kun Wu Shih-Cheng Yang Chih-Ming Liang Pin-I Hsu Seng-Kee Chuah Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

The multicenter real-world report of the efficacies of 14-day esomeprazole-based and rabeprazole-based high-dose dual therapy in first-line Helicobacter pylori eradication in Taiwan
CONCLUSIONS: Esomeprazole-based HDDT achieved over 90% eradication rates but rabeprazole-based HDDT, which failed.PMID:38461114 | DOI:10.1016/j.jmii.2024.02.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 9, 2024 Category: Microbiology Authors: Wei-Chen Tai I-Ting Wu Hsin-Ming Wang Pao-Yuan Huang Chih-Chien Yao Cheng-Kun Wu Shih-Cheng Yang Chih-Ming Liang Pin-I Hsu Seng-Kee Chuah Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research

The multicenter real-world report of the efficacies of 14-day esomeprazole-based and rabeprazole-based high-dose dual therapy in first-line Helicobacter pylori eradication in Taiwan
CONCLUSIONS: Esomeprazole-based HDDT achieved over 90% eradication rates but rabeprazole-based HDDT, which failed.PMID:38461114 | DOI:10.1016/j.jmii.2024.02.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 9, 2024 Category: Microbiology Authors: Wei-Chen Tai I-Ting Wu Hsin-Ming Wang Pao-Yuan Huang Chih-Chien Yao Cheng-Kun Wu Shih-Cheng Yang Chih-Ming Liang Pin-I Hsu Seng-Kee Chuah Source Type: research

Safety of direct oral provocation test to delabel reported mild beta-lactam allergy in infants
CONCLUSIONS: A direct DPT without prior tests is a safe and effective procedure to delabel BL allergy, even in infants. The authors wish to emphasize the importance of properly validating BL allergy suspicions by promoting appropriate diagnostic procedures in infants as, in most cases, DHRs can be excluded and there is no need for further therapeutic restrictions.PMID:38459885 | DOI:10.15586/aei.v52i2.887 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Francisca Cunha In ês Cunha Eva Gomes Source Type: research