Molecules, Vol. 29, Pages 1225: Essential Oil Compounds in Combination with Conventional Antibiotics for Dermatology
This study aimed to determine the possible interactions between six essential oil compounds with eight antibiotics/antifungals against six pathogens (Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Acinetobacter baumannii, Cutibacterium acnes, and Candida albicans) commonly implicated in skin infections. The minimum inhibitory concentrations (MICs) for the antibiotics and essential oil compounds were evaluated singularly and in combination using the broth microdilution assay. The fractional inhibitory concentrations (FIC) were calculated to determine the interactive profile of the combinations. T...
Source: Molecules - March 8, 2024 Category: Chemistry Authors: Shivar Simbu An é Orchard Sandy van Vuuren Tags: Article Source Type: research
Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting
CONCLUSION: New associations between commonly prescribed antepartum medications and orofacial clefting were found. These findings should be confirmed as causality is not assessed in this report. Practitioners should be aware of the potential increased risk associated with these medications.PMID:38449319 | DOI:10.1177/10556656241237679 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - March 7, 2024 Category: ENT & OMF Authors: Matteo Laspro Hilliard T Brydges Alexandra N Verzella Jill Schechter Andre Alcon Ashley S Roman Roberto L Flores Source Type: research
A comparative analysis of univariate versus multivariate eco-friendly spectrophotometric manipulations for resolving severely overlapped spectra of vonoprazan and amoxicillin new combination
Anal Biochem. 2024 Mar 5:115501. doi: 10.1016/j.ab.2024.115501. Online ahead of print.ABSTRACTVonoprazan and amoxicillin are pharmacological combinations that demonstrate synergistic effects in treating Helicobacter pylori (H. pylori), a global public health concern associated with peptic ulcer disease and gastric cancer. Four spectrophotometric methods were developed, including two univariate techniques (Fourier self-deconvolution and ratio difference) and two multivariate chemometric approaches (partial least squares and principal component regression). These methods provide innovative solutions for effectively resolving...
Source: Analytical Biochemistry - March 7, 2024 Category: Biochemistry Authors: Ahmed K Kammoun Hani M Hafez Ebraam B Kamel Michael Gamal Fawzy Source Type: research
Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting
CONCLUSION: New associations between commonly prescribed antepartum medications and orofacial clefting were found. These findings should be confirmed as causality is not assessed in this report. Practitioners should be aware of the potential increased risk associated with these medications.PMID:38449319 | DOI:10.1177/10556656241237679 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - March 7, 2024 Category: ENT & OMF Authors: Matteo Laspro Hilliard T Brydges Alexandra N Verzella Jill Schechter Andre Alcon Ashley S Roman Roberto L Flores Source Type: research
A comparative analysis of univariate versus multivariate eco-friendly spectrophotometric manipulations for resolving severely overlapped spectra of vonoprazan and amoxicillin new combination
Anal Biochem. 2024 Mar 5:115501. doi: 10.1016/j.ab.2024.115501. Online ahead of print.ABSTRACTVonoprazan and amoxicillin are pharmacological combinations that demonstrate synergistic effects in treating Helicobacter pylori (H. pylori), a global public health concern associated with peptic ulcer disease and gastric cancer. Four spectrophotometric methods were developed, including two univariate techniques (Fourier self-deconvolution and ratio difference) and two multivariate chemometric approaches (partial least squares and principal component regression). These methods provide innovative solutions for effectively resolving...
Source: Analytical Biochemistry - March 7, 2024 Category: Biochemistry Authors: Ahmed K Kammoun Hani M Hafez Ebraam B Kamel Michael Gamal Fawzy Source Type: research
Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting
CONCLUSION: New associations between commonly prescribed antepartum medications and orofacial clefting were found. These findings should be confirmed as causality is not assessed in this report. Practitioners should be aware of the potential increased risk associated with these medications.PMID:38449319 | DOI:10.1177/10556656241237679 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - March 7, 2024 Category: ENT & OMF Authors: Matteo Laspro Hilliard T Brydges Alexandra N Verzella Jill Schechter Andre Alcon Ashley S Roman Roberto L Flores Source Type: research
Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting
CONCLUSION: New associations between commonly prescribed antepartum medications and orofacial clefting were found. These findings should be confirmed as causality is not assessed in this report. Practitioners should be aware of the potential increased risk associated with these medications.PMID:38449319 | DOI:10.1177/10556656241237679 (Source: The Cleft Palate-Craniofacial Journal)
Source: The Cleft Palate-Craniofacial Journal - March 7, 2024 Category: ENT & OMF Authors: Matteo Laspro Hilliard T Brydges Alexandra N Verzella Jill Schechter Andre Alcon Ashley S Roman Roberto L Flores Source Type: research
Empiric use of standard triple therapy in Helicobacter pylori eradication does not require readjustment in the clarithromycin resistance cut-off point
We appreciate the considerations of Hsu et al about the recommendation of empiric first-line therapies in our Maastricht VI/Florence consensus report for the management of Helicobacter pylori.1 2 We fully agree that H. pylori eradication therapy should aim at a cure rate of ≥90%. This also meets the expectation of patients as referred by the authors from a real-world expectation survey of the Asia-Pacific region.3 However, we disagree that the cut-off for clarithromycin resistance, at least for now, is too high at 15% for triple therapy consisting of proton pump inhibitor (PPI), amoxicillin and clarithromycin used as em...
Source: Gut - March 7, 2024 Category: Gastroenterology Authors: Malfertheiner, P., Megraud, F., Rokkas, T., Gisbert, J. P. Tags: Gut PostScript Source Type: research
Management of Acne in Pregnancy
AbstractAcne is one of the most common dermatological conditions to affect women of childbearing age, so it is important to consider the safety of long-term acne treatments on women who could become pregnant. In this review article, we clarify what management options are available to treat acne during pregnancy. Topical treatments, typically first-line for acne, such as azelaic acid, clindamycin, erythromycin, metronidazole, benzoyl peroxide, salicylic acid, dapsone, and retinoids, were reviewed. Systemic treatments, such as zinc supplements, cephalexin, cefadroxil, amoxicillin, azithromycin, erythromycin, and corticostero...
Source: American Journal of Clinical Dermatology - March 7, 2024 Category: Dermatology Source Type: research
Time series-based prediction of antibiotic degradation via photocatalysis using ensemble gradient boosting
This study aims to evaluate the effectiveness of the laboratory-made catalyst Ni2P-ZrO2 (NPZ) in the degradation of an antibiotic in an aqueous suspension when exposed to ultraviolet (UV) light. The degradation of amoxicillin (AMX) was predicted using time series forecasting through the ensemble gradient boosting model. The degradation experiments were conducted utilizing two distinct photocatalyst compositions of Nickel phosphide-zirconium dioxide (NPZ) in the proportions of 1:9 and 2:8. The most effective experimental results were obtained using a natural pH, a catalyst concentration of 0.20 g/L and reaction duration of ...
Source: Environmental Science and Pollution Research International - March 5, 2024 Category: Environmental Health Authors: Sheetal Sethi Amit Dhir Vinay Arora Source Type: research
Time series-based prediction of antibiotic degradation via photocatalysis using ensemble gradient boosting
This study aims to evaluate the effectiveness of the laboratory-made catalyst Ni2P-ZrO2 (NPZ) in the degradation of an antibiotic in an aqueous suspension when exposed to ultraviolet (UV) light. The degradation of amoxicillin (AMX) was predicted using time series forecasting through the ensemble gradient boosting model. The degradation experiments were conducted utilizing two distinct photocatalyst compositions of Nickel phosphide-zirconium dioxide (NPZ) in the proportions of 1:9 and 2:8. The most effective experimental results were obtained using a natural pH, a catalyst concentration of 0.20 g/L and reaction duration of ...
Source: Environmental Science and Pollution Research International - March 5, 2024 Category: Environmental Health Authors: Sheetal Sethi Amit Dhir Vinay Arora Source Type: research
Involvement of autologous myeloid dendritic cells in the evaluation of immediate hypersensitivity reactions to betalactams
CONCLUSIONS: mDCs from selective AP efficiently recognise the culprit drug which trigger the IDHR. mDCs also trigger proliferation of lymphocytes, mainly those with a Th2 cytokine pattern, although these responses depend on the nature of the drug, mimicking the patient's reaction.PMID:38432423 | DOI:10.1016/j.clim.2024.110166 (Source: Clinical Immunology)
Source: Clinical Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Ruben Fernandez-Santamaria Adriana Ariza Gador Bogas Maria Salas Silvia Calvo Cecilia Frecha C Cristobalina Mayorga Maria Jose Torres Tahia Diana Fernandez Source Type: research
Involvement of autologous myeloid dendritic cells in the evaluation of immediate hypersensitivity reactions to betalactams
CONCLUSIONS: mDCs from selective AP efficiently recognise the culprit drug which trigger the IDHR. mDCs also trigger proliferation of lymphocytes, mainly those with a Th2 cytokine pattern, although these responses depend on the nature of the drug, mimicking the patient's reaction.PMID:38432423 | DOI:10.1016/j.clim.2024.110166 (Source: Clinical Immunology)
Source: Clinical Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Ruben Fernandez-Santamaria Adriana Ariza Gador Bogas Maria Salas Silvia Calvo Cecilia Frecha C Cristobalina Mayorga Maria Jose Torres Tahia Diana Fernandez Source Type: research
Involvement of autologous myeloid dendritic cells in the evaluation of immediate hypersensitivity reactions to betalactams
CONCLUSIONS: mDCs from selective AP efficiently recognise the culprit drug which trigger the IDHR. mDCs also trigger proliferation of lymphocytes, mainly those with a Th2 cytokine pattern, although these responses depend on the nature of the drug, mimicking the patient's reaction.PMID:38432423 | DOI:10.1016/j.clim.2024.110166 (Source: Clinical Immunology)
Source: Clinical Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Ruben Fernandez-Santamaria Adriana Ariza Gador Bogas Maria Salas Silvia Calvo Cecilia Frecha C Cristobalina Mayorga Maria Jose Torres Tahia Diana Fernandez Source Type: research
Involvement of autologous myeloid dendritic cells in the evaluation of immediate hypersensitivity reactions to betalactams
CONCLUSIONS: mDCs from selective AP efficiently recognise the culprit drug which trigger the IDHR. mDCs also trigger proliferation of lymphocytes, mainly those with a Th2 cytokine pattern, although these responses depend on the nature of the drug, mimicking the patient's reaction.PMID:38432423 | DOI:10.1016/j.clim.2024.110166 (Source: Clinical Immunology)
Source: Clinical Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Ruben Fernandez-Santamaria Adriana Ariza Gador Bogas Maria Salas Silvia Calvo Cecilia Frecha C Cristobalina Mayorga Maria Jose Torres Tahia Diana Fernandez Source Type: research
