Involvement of autologous myeloid dendritic cells in the evaluation of immediate hypersensitivity reactions to betalactams

CONCLUSIONS: mDCs from selective AP efficiently recognise the culprit drug which trigger the IDHR. mDCs also trigger proliferation of lymphocytes, mainly those with a Th2 cytokine pattern, although these responses depend on the nature of the drug, mimicking the patient's reaction.PMID:38432423 | DOI:10.1016/j.clim.2024.110166

Source: Clinical Immunology - March 3, 2024 Category: Allergy & Immunology Authors: Ruben Fernandez-Santamaria Adriana Ariza Gador Bogas Maria Salas Silvia Calvo Cecilia Frecha C Cristobalina Mayorga Maria Jose Torres Tahia Diana Fernandez Source Type: research