Hemoglobin uptake and utilization by human protozoan parasites: a review
The protozoan disease is a major global health concern. Amoebiasis, leishmaniasis, Chagas disease, and African sleeping sickness affect several million people worldwide, leading to millions of deaths annually and immense social and economic problems. Iron is an essential nutrient for nearly all microbes, including invading pathogens. The majority of iron in mammalian hosts is stored intracellularly in proteins, such as ferritin and hemoglobin (Hb). Hb, present in blood erythrocytes, is a very important source of iron and amino acids for pathogenic microorganisms ranging from bacteria to eukaryotic pathogens, such as worms,...
Source: Frontiers in cellular and infection microbiology - June 9, 2023 Category: Microbiology Source Type: research
Unraveling the genetic mechanisms governing the host response to bovine anaplasmosis
This study provides comprehensive information about the crosstalk of genes involved in host defense as well as parasite persistence in the host upon infection with A. marginale.PMID:37279864 | DOI:10.1016/j.gene.2023.147532 (Source: Gene)
Source: Gene - June 6, 2023 Category: Genetics & Stem Cells Authors: Sonika Ahlawat Vikas Choudhary Rashmeet Kaur Reena Arora Rekha Sharma Formal Analyses Pooja Chhabra Formal Analyses Ashish Kumar Mandeep Kaur Source Type: research
Unraveling the genetic mechanisms governing the host response to bovine anaplasmosis
This study provides comprehensive information about the crosstalk of genes involved in host defense as well as parasite persistence in the host upon infection with A. marginale.PMID:37279864 | DOI:10.1016/j.gene.2023.147532 (Source: Gene)
Source: Gene - June 6, 2023 Category: Genetics & Stem Cells Authors: Sonika Ahlawat Vikas Choudhary Rashmeet Kaur Reena Arora Rekha Sharma Formal Analyses Pooja Chhabra Formal Analyses Ashish Kumar Mandeep Kaur Source Type: research
Metronidazole induced cutaneous adverse drug reaction- a systematic review of descriptive studies
CONCLUSION: Clinicians and healthcare professionals should be cognizant of the potential cutaneous adverse drug reactions (CADRs) induced by metronidazole to mitigate fatal circumstances. The management of the CADRs appears to respond effectively with immediate drug discontinuation and supportive therapy.PMID:37264661 | DOI:10.2174/2772432819666230601155545 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - June 2, 2023 Category: Drugs & Pharmacology Authors: Shifa Taj Mohammed Zuber Vidhyashree B H Rajesh Venkataraman Sathish Kumar Bp Syed Afrid Sai Kiran Source Type: research
Metronidazole induced cutaneous adverse drug reaction- a systematic review of descriptive studies
CONCLUSION: Clinicians and healthcare professionals should be cognizant of the potential cutaneous adverse drug reactions (CADRs) induced by metronidazole to mitigate fatal circumstances. The management of the CADRs appears to respond effectively with immediate drug discontinuation and supportive therapy.PMID:37264661 | DOI:10.2174/2772432819666230601155545 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - June 2, 2023 Category: Drugs & Pharmacology Authors: Shifa Taj Mohammed Zuber Vidhyashree B H Rajesh Venkataraman Sathish Kumar Bp Syed Afrid Sai Kiran Source Type: research
Metronidazole induced cutaneous adverse drug reaction- a systematic review of descriptive studies
CONCLUSION: Clinicians and healthcare professionals should be cognizant of the potential cutaneous adverse drug reactions (CADRs) induced by metronidazole to mitigate fatal circumstances. The management of the CADRs appears to respond effectively with immediate drug discontinuation and supportive therapy.PMID:37264661 | DOI:10.2174/2772432819666230601155545 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - June 2, 2023 Category: Drugs & Pharmacology Authors: Shifa Taj Mohammed Zuber Vidhyashree B H Rajesh Venkataraman Sathish Kumar Bp Syed Afrid Sai Kiran Source Type: research
Metronidazole induced cutaneous adverse drug reaction- a systematic review of descriptive studies
CONCLUSION: Clinicians and healthcare professionals should be cognizant of the potential cutaneous adverse drug reactions (CADRs) induced by metronidazole to mitigate fatal circumstances. The management of the CADRs appears to respond effectively with immediate drug discontinuation and supportive therapy.PMID:37264661 | DOI:10.2174/2772432819666230601155545 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - June 2, 2023 Category: Drugs & Pharmacology Authors: Shifa Taj Mohammed Zuber Vidhyashree B H Rajesh Venkataraman Sathish Kumar Bp Syed Afrid Sai Kiran Source Type: research
The Gal/GalNac lectin as a possible acetylcholine receptor in Entamoeba histolytica
In conclusion, ACh is captured by the parasite, and the interaction promotes the activation of signaling pathways involved in pathogenicity mechanisms, contributing to disease and the establishment of invasive amebiasis. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - May 16, 2023 Category: Microbiology Source Type: research
Prevalence and molecular characterization of < i > Entamoeba moshkovskii < /i > in diarrheal patients from Eastern India
In this study, we determined the prevalence and characterized the E. moshkovskii isolates in eastern India. MethodsA three-year systemic surveillance study among a total of 6051 diarrhoeal patients from ID Hospital and BC Roy Hospital, Kolkata was conducted for E. moshkovskii detection via a nested PCR system targeting 18S rRNA locus. The outer primer set detected the genus Entamoeba and the inner primer pair identified the E. moshkovskii species. The 18S rRNA locus of the positive samples was sequenced. Genetic and phylogenetic structures were determined using DnaSP.v5 and MEGA-X. GraphPad Prism (v.8.4.2), CA, USA was use...
Source: PLoS Neglected Tropical Diseases - May 11, 2023 Category: Tropical Medicine Authors: Sanjib K. Sardar Source Type: research
Prevalence of amoebiasis and associated risk factors among population in Duhok city, Kurdistan Region, Iraq
Conclusions: The present study concluded that improving living conditions, providing clean water, and promoting health education programs are essential to reduce the rate of this disease among the population. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - April 29, 2023 Category: Infectious Diseases Authors: Haliz Khalid Hasan, Wijdan Mohammed Salih Mero, Ahmed Basheer Mohammed Source Type: research
A multi-epitope based vaccine against the surface proteins expressed in cyst and trophozoite stages of parasite Entamoeba histolytica
J Immunol Methods. 2023 Apr 21:113475. doi: 10.1016/j.jim.2023.113475. Online ahead of print.ABSTRACTEntamoeba histolytica, an anaerobic parasite, infects humans and other primates and causes fatal diseases, such as amebiasis, amebic liver abscesses, and many others. Thousands of people are infected and dying due to the need for a proper protective cure, especially in poor sanitizing regions, such as Latin America, Asia, and Africa. Around 10% of the world population is infected by E. histolytica every year. Consequently, novel preventive approaches are required to eliminate the threats of the parasite. A designed vaccine ...
Source: Journal of Immunological Methods - April 23, 2023 Category: Allergy & Immunology Authors: Dipankor Chatterjee Razoan Al Rimon Umar Faruq Chowdhury Mohammad Riazul Islam Source Type: research
A multi-epitope based vaccine against the surface proteins expressed in cyst and trophozoite stages of parasite Entamoeba histolytica
J Immunol Methods. 2023 Apr 21:113475. doi: 10.1016/j.jim.2023.113475. Online ahead of print.ABSTRACTEntamoeba histolytica, an anaerobic parasite, infects humans and other primates and causes fatal diseases, such as amebiasis, amebic liver abscesses, and many others. Thousands of people are infected and dying due to the need for a proper protective cure, especially in poor sanitizing regions, such as Latin America, Asia, and Africa. Around 10% of the world population is infected by E. histolytica every year. Consequently, novel preventive approaches are required to eliminate the threats of the parasite. A designed vaccine ...
Source: Journal of Immunological Methods - April 23, 2023 Category: Allergy & Immunology Authors: Dipankor Chatterjee Razoan Al Rimon Umar Faruq Chowdhury Mohammad Riazul Islam Source Type: research
A multi-epitope based vaccine against the surface proteins expressed in cyst and trophozoite stages of parasite Entamoeba histolytica
J Immunol Methods. 2023 Apr 21:113475. doi: 10.1016/j.jim.2023.113475. Online ahead of print.ABSTRACTEntamoeba histolytica, an anaerobic parasite, infects humans and other primates and causes fatal diseases, such as amebiasis, amebic liver abscesses, and many others. Thousands of people are infected and dying due to the need for a proper protective cure, especially in poor sanitizing regions, such as Latin America, Asia, and Africa. Around 10% of the world population is infected by E. histolytica every year. Consequently, novel preventive approaches are required to eliminate the threats of the parasite. A designed vaccine ...
Source: Journal of Immunological Methods - April 21, 2023 Category: Allergy & Immunology Authors: Dipankor Chatterjee Razoan Al Rimon Umar Faruq Chowdhury Mohammad Riazul Islam Source Type: research
Right basal bronchial fistula due to amebic infection: a case report
Pleuropulmonary amebiasis is the second most common form of extraintestinal invasive amebiasis, but cases that include bronchopleural fistula are rare. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 14, 2023 Category: Respiratory Medicine Authors: Tomohiro Yazawa, Hitoshi Igai, Mitsuhiro Kamiyoshihara and Ken Shirabe Tags: Case report Source Type: research
