Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 4:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential bio...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 4:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential bio...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 4:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential bio...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 4:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential bio...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 4:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential bio...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 5;280:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Proteomic and N-glycoproteomic analyses of total subchondral bone protein in patients with primary knee osteoarthritis
J Proteomics. 2023 Apr 5;280:104896. doi: 10.1016/j.jprot.2023.104896. Online ahead of print.ABSTRACTN-glycosylation is an important post-translational modification necessary to maintain the structural and functional properties of proteins. Impaired N-glycosylation has been observed in several diseases. It is significantly modified by the state of cells and is used as a diagnostic or prognostic indicator for multiple human diseases, including cancer and osteoarthritis (OA). Aim of the study was to explore the N-glycosylation levels of subchondral bone proteins in patients with primary knee OA (KOA) and screen for potential...
Source: Journal of Proteomics - April 6, 2023 Category: Biochemistry Authors: Gangning Feng Yong Zhou Jiangbo Yan Zheng Wang Yong Yang Weidong Zhao Na Wang Zhidong Lu Yaogeng Chen Qunhua Jin Source Type: research
Entamoeba histolytica induced NETosis and the dual role of NETs in amoebiasiss
Int Immunopharmacol. 2023 Apr 1;118:110100. doi: 10.1016/j.intimp.2023.110100. Online ahead of print.ABSTRACTEntamoeba histolytica (Eh), a microaerophilic parasite, causes deadly enteric infections that result in Amoebiasis. Every year, the count of invasive infections reaches 50 million approximately and 40,000 to 1,00,000 deaths occurring due to amoebiasis are reported globally. Profound inflammation is the hallmark of severe amoebiasis which is facilitated by immune first defenders, neutrophils. Due to size incompatibility, neutrophils are unable to phagocytose Eh and thus, came up with the miraculous antiparasitic mech...
Source: International Immunopharmacology - April 3, 2023 Category: Allergy & Immunology Authors: Mrinalini Roy Shreya Chakraborty Sandeep Kumar Srivastava Sanket Kaushik Anupam Jyoti Vijay Kumar Srivastava Source Type: research
Systematic Analysis of the Prognostic Significance and Roles of the Integrin Alpha Family in Non-Small Cell Lung Cancers
CONCLUSION: As potential prognostic biomarkers in NSCLCs, ITGA5/8/9/L may fulfill important roles in regulating tumor progression and immune cell infiltration.PMID:36892810 | DOI:10.1007/s12325-023-02469-2 (Source: Adv Data)
Source: Adv Data - March 9, 2023 Category: Epidemiology Authors: Yu Huang Dong-Ming Guo Shi Bu Wei Xu Qing-Chun Cai Jian Xu Yue-Quan Jiang Fei Teng Source Type: research
Systematic Analysis of the Prognostic Significance and Roles of the Integrin Alpha Family in Non-Small Cell Lung Cancers
ConclusionAs potential prognostic biomarkers in NSCLCs, ITGA5/8/9/L may fulfill important roles in regulating tumor progression and immune cell infiltration. (Source: Advances in Therapy)
Source: Advances in Therapy - March 9, 2023 Category: Drugs & Pharmacology Source Type: research
A systematic review of frequency and geographic distribution of water-borne parasites in the Middle East and North Africa
CONCLUSIONS: Water-borne parasites are still endemic in many MENA countries, however, their incidence has reduced dramatically due to the control and eradication programmes in countries that could afford such programmes, some with external support and funding.PMID:36880497 | DOI:10.26719/emhj.23.016 (Source: Eastern Mediterranean Health Journal)
Source: Eastern Mediterranean Health Journal - March 7, 2023 Category: Middle East Health Authors: Sameh Abuseir Source Type: research
