Anaerobic energy metabolism in human microaerophile parasites
Exp Parasitol. 2023 Feb 23:108492. doi: 10.1016/j.exppara.2023.108492. Online ahead of print.ABSTRACTMucosal-associated parasites, such as Giardia intestinalis, Entamoeba histolytica, and Trichomonas vaginalis, have significant clinical relevance. The pathologies associated with infection by these parasites are among those with the highest incidence of gastroenteritis (giardiasis and amoebiasis) and sexually transmitted infections (trichomoniasis). The treatment of these diseases is based on drugs that act on the anaerobic metabolism of these parasites, such as nitroimidazole and benzimidazole derivatives. One interesting ...
Source: Experimental Parasitology - February 25, 2023 Category: Parasitology Authors: Ayra Diandra Carvalho-de-Ara újo Luiz Fernando Carvalho-Kelly Jos é Roberto Meyer-Fernandes Source Type: research
Anaerobic energy metabolism in human microaerophile parasites
Exp Parasitol. 2023 Feb 23:108492. doi: 10.1016/j.exppara.2023.108492. Online ahead of print.ABSTRACTMucosal-associated parasites, such as Giardia intestinalis, Entamoeba histolytica, and Trichomonas vaginalis, have significant clinical relevance. The pathologies associated with infection by these parasites are among those with the highest incidence of gastroenteritis (giardiasis and amoebiasis) and sexually transmitted infections (trichomoniasis). The treatment of these diseases is based on drugs that act on the anaerobic metabolism of these parasites, such as nitroimidazole and benzimidazole derivatives. One interesting ...
Source: Experimental Parasitology - February 25, 2023 Category: Parasitology Authors: Ayra Diandra Carvalho-de-Ara újo Luiz Fernando Carvalho-Kelly Jos é Roberto Meyer-Fernandes Source Type: research
Anaerobic energy metabolism in human microaerophile parasites
Exp Parasitol. 2023 Feb 23:108492. doi: 10.1016/j.exppara.2023.108492. Online ahead of print.ABSTRACTMucosal-associated parasites, such as Giardia intestinalis, Entamoeba histolytica, and Trichomonas vaginalis, have significant clinical relevance. The pathologies associated with infection by these parasites are among those with the highest incidence of gastroenteritis (giardiasis and amoebiasis) and sexually transmitted infections (trichomoniasis). The treatment of these diseases is based on drugs that act on the anaerobic metabolism of these parasites, such as nitroimidazole and benzimidazole derivatives. One interesting ...
Source: Experimental Parasitology - February 25, 2023 Category: Parasitology Authors: Ayra Diandra Carvalho-de-Ara újo Luiz Fernando Carvalho-Kelly Jos é Roberto Meyer-Fernandes Source Type: research
GSE219293 Differential DNA Methylation Associated with Multiple Sclerosis in an Underrepresented Population and Disease Modifying Treatments in an Underrepresented Minority Population
The objectives were to identify differential methylation of genomic DNA (gDNA) associated with disease susceptibility and treatment responses in a cohort of MS patients from underrepresented minority populations. Patients with MS and controls with non-inflammatory neurologic conditions were consented and enrolled under an IRB-approved protocol. Approximately 64% of donors identified as Black or African American and 30% as White, Hispanic-Latino. Infinium MethylationEPIC bead arrays were utilized to measure epigenome-wide gDNA methylation of whole blood. Data were analyzed in the presence and absence of adjustments for un...
Source: GEO: Gene Expression Omnibus - February 7, 2023 Category: Genetics & Stem Cells Tags: Methylation profiling by genome tiling array Homo sapiens Source Type: research
