Bone morphogenetic protein 1: a prognostic indicator and potential biomarker in three cancer types
CONCLUSION: In conclusion, our study has provided some solid basis for BMP1 to be used as a reliable common biomarker for BLCA, KIRC, and LUAD patients.PMID:38463598 | PMC:PMC10918118 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - March 11, 2024 Category: Research Authors: Ming Wang Chunmei Liu Yingjie Wang Muhammad Jamil Majid Alhomrani Abdulhakeem S Alamri Walaa F Alsanie Abdulaziz Alsharif Mubarik Ali Norina Jabeen Source Type: research
Bone morphogenetic protein 1: a prognostic indicator and potential biomarker in three cancer types
CONCLUSION: In conclusion, our study has provided some solid basis for BMP1 to be used as a reliable common biomarker for BLCA, KIRC, and LUAD patients.PMID:38463598 | PMC:PMC10918118 | DOI:10.62347/PWZA6242 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - March 11, 2024 Category: Research Authors: Ming Wang Chunmei Liu Yingjie Wang Muhammad Jamil Majid Alhomrani Abdulhakeem S Alamri Walaa F Alsanie Abdulaziz Alsharif Mubarik Ali Norina Jabeen Source Type: research
Bone morphogenetic protein 1: a prognostic indicator and potential biomarker in three cancer types
CONCLUSION: In conclusion, our study has provided some solid basis for BMP1 to be used as a reliable common biomarker for BLCA, KIRC, and LUAD patients.PMID:38463598 | PMC:PMC10918118 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - March 11, 2024 Category: Research Authors: Ming Wang Chunmei Liu Yingjie Wang Muhammad Jamil Majid Alhomrani Abdulhakeem S Alamri Walaa F Alsanie Abdulaziz Alsharif Mubarik Ali Norina Jabeen Source Type: research
Bone morphogenetic protein 1: a prognostic indicator and potential biomarker in three cancer types
CONCLUSION: In conclusion, our study has provided some solid basis for BMP1 to be used as a reliable common biomarker for BLCA, KIRC, and LUAD patients.PMID:38463598 | PMC:PMC10918118 | DOI:10.62347/PWZA6242 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - March 11, 2024 Category: Research Authors: Ming Wang Chunmei Liu Yingjie Wang Muhammad Jamil Majid Alhomrani Abdulhakeem S Alamri Walaa F Alsanie Abdulaziz Alsharif Mubarik Ali Norina Jabeen Source Type: research
Bone morphogenetic protein 1: a prognostic indicator and potential biomarker in three cancer types
CONCLUSION: In conclusion, our study has provided some solid basis for BMP1 to be used as a reliable common biomarker for BLCA, KIRC, and LUAD patients.PMID:38463598 | PMC:PMC10918118 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - March 11, 2024 Category: Research Authors: Ming Wang Chunmei Liu Yingjie Wang Muhammad Jamil Majid Alhomrani Abdulhakeem S Alamri Walaa F Alsanie Abdulaziz Alsharif Mubarik Ali Norina Jabeen Source Type: research
Usefulness of a new immunochromatographic assay using fluorescent silica nanoparticles for serodiagnosis of Thai patients with amebiasis
Drug Discov Ther. 2024 Feb 15. doi: 10.5582/ddt.2023.01102. Online ahead of print.ABSTRACTA fluorescence immunochromatography (FIC) kit was developed recently using fluorescent silica nanoparticles coated with a recombinant C-terminal fragment of the surface lectin intermediate subunit (C-Igl) of Entamoeba histolytica to establish rapid serodiagnosis of amebiasis. We further evaluated the system using serum samples from 52 Thai patients with amebiasis. Of the patients, 50 (96%) tested positive using FIC. The samples were also tested using enzyme-linked immunosorbent assay (ELISA) with C-Igl as the antigen. Two samples were...
Source: Drug Discoveries and Therapeutics - February 14, 2024 Category: Drugs & Pharmacology Authors: Azumi Kakino Urassaya Pattanawong Napaporn Kuamsab Tatsuya Imai Chaturong Putaporntip Satomi Asai Xunjia Cheng Somchai Jongwutiwes Hiroshi Tachibana Source Type: research
Inhibition of choline kinase as an antiamoebic approach in Entamoeba histolytica infection
This study investigates a novel anti-amoebic approach targeting the CDP-choline pathway. Inhibition studies were conducted using potential choline kinase (CK) inhibitors to inhibit the EhCK enzyme, and RNA interference was employed to knock down the EhCK gene. Km and Vmax of purified EhCK and hCKa2 proteins were determined by pyruvate kinase-lactate dehydrogenase (PK-LDH) coupled assay. The IC50 values for EhCK and hCKa2 were determined with several commercial CK inhibitors. Selected inhibitors were incubated with E. histolytica trophozoites for 48 hours to determine the EC50 for each inhibitor. Silencing of gene encoding ...
Source: Tropical Biomedicine - February 3, 2024 Category: Tropical Medicine Authors: Z H Teh B H Lim W C See Too L L Few Source Type: research
