Histocompatibility assessment in hematopoietic stem cell transplantation: recommendations from the Italian Association of Immunogenetics and Biology of Transplantation (Associazione Italiana di Immunogenetica e Biologia dei Trapianti - AIBT)
Blood Transfus. 2023 Jun 12. doi: 10.2450/BloodTransfus.495. Online ahead of print.ABSTRACTThe outcome of allogeneic hematopoietic stem cell transplantation (HSCT) is significantly influenced by the degree of HLA histocompatibility between donor and recipient. To provide shared indications for required histocompatibility testing and interpretation before HSCT, the Italian Society for Immunogenetics and Transplantation Biology (Associazione Italiana di Immunogenetica e Biologia dei Trapianti [AIBT]) gathered members and created a working group to discuss and develop recommendations for histocompatibility assessment in HSCT....
Source: Blood Transfusion - July 17, 2023 Category: Hematology Authors: Roberto Crocchiolo Caterina Fusco Marco Andreani Giovanni Rombol à Michela Falco Cinzia Vecchiato Lucia Garbarino Lia Mele Allegra B Mazzi Alessandra Picardi Letizia Lombardini Simona Pollichieni Maria C De Stefano Fabio Ciceri Massimo Cardillo Franco Pa Source Type: research
Histocompatibility assessment in hematopoietic stem cell transplantation: recommendations from the Italian Association of Immunogenetics and Biology of Transplantation (Associazione Italiana di Immunogenetica e Biologia dei Trapianti - AIBT)
Blood Transfus. 2023 Jun 12. doi: 10.2450/BloodTransfus.495. Online ahead of print.ABSTRACTThe outcome of allogeneic hematopoietic stem cell transplantation (HSCT) is significantly influenced by the degree of HLA histocompatibility between donor and recipient. To provide shared indications for required histocompatibility testing and interpretation before HSCT, the Italian Society for Immunogenetics and Transplantation Biology (Associazione Italiana di Immunogenetica e Biologia dei Trapianti [AIBT]) gathered members and created a working group to discuss and develop recommendations for histocompatibility assessment in HSCT....
Source: Blood Transfusion - July 17, 2023 Category: Hematology Authors: Roberto Crocchiolo Caterina Fusco Marco Andreani Giovanni Rombol à Michela Falco Cinzia Vecchiato Lucia Garbarino Lia Mele Allegra B Mazzi Alessandra Picardi Letizia Lombardini Simona Pollichieni Maria C De Stefano Fabio Ciceri Massimo Cardillo Franco Pa Source Type: research
Histocompatibility assessment in hematopoietic stem cell transplantation: recommendations from the Italian Association of Immunogenetics and Biology of Transplantation (Associazione Italiana di Immunogenetica e Biologia dei Trapianti - AIBT)
Blood Transfus. 2023 Jun 12. doi: 10.2450/BloodTransfus.495. Online ahead of print.ABSTRACTThe outcome of allogeneic hematopoietic stem cell transplantation (HSCT) is significantly influenced by the degree of HLA histocompatibility between donor and recipient. To provide shared indications for required histocompatibility testing and interpretation before HSCT, the Italian Society for Immunogenetics and Transplantation Biology (Associazione Italiana di Immunogenetica e Biologia dei Trapianti [AIBT]) gathered members and created a working group to discuss and develop recommendations for histocompatibility assessment in HSCT....
Source: Blood Transfusion - July 17, 2023 Category: Hematology Authors: Roberto Crocchiolo Caterina Fusco Marco Andreani Giovanni Rombol à Michela Falco Cinzia Vecchiato Lucia Garbarino Lia Mele Allegra B Mazzi Alessandra Picardi Letizia Lombardini Simona Pollichieni Maria C De Stefano Fabio Ciceri Massimo Cardillo Franco Pa Source Type: research
Psychological and Psychiatric Aspects of Brain and Spinal Cord Tumors
Adv Exp Med Biol. 2023;1405:673-687. doi: 10.1007/978-3-031-23705-8_26.ABSTRACTCentral nervous system (CNS) tumors are mainly diagnosed by physical symptoms such as paralysis, visual field defect, seizure, and loss of consciousness. The psychological and psychiatric background of CNS tumors, whether in preoperative or postoperative period, has long been a neglected topic; however, lately, many authors and researchers have paid more attention to these manifestations. Neurocognition is a subset of parameters, including attention, memory, mood, emotions, language production, personality, executive function, problem-solving, c...
Source: Advances in Experimental Medicine and Biology - July 15, 2023 Category: Research Authors: Ahmad Pour-Rashidi Mohamad Namvar Arad Iranmehr Allegra Carpaneto Sara Hanaei Nima Rezaei Source Type: research
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression
Extracellular vesicles (EVs) harbor a plethora of different biomolecules, which they can transport across cells. In cancer, tumor-derived EVs thereby support the creation of a favorable tumor microenvironment.... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - July 10, 2023 Category: Molecular Biology Authors: Barnabas Irmer, Janes Efing, Lea Elisabeth Reitnauer, Allegra Angenendt, Saskia Heinrichs, Antonia Schubert, Matthias Schulz, Claudia Binder, Joke Tio, Uwe Hansen, Christiane Geyer, Mirjam Gerwing, Annalen Bleckmann and Kerstin Menck Tags: Research Source Type: research
Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration
Curr Neuropharmacol. 2023 Jul 5. doi: 10.2174/1570159X21666230705103839. Online ahead of print.ABSTRACTDefective autophagy in the retinal pigment epithelium (RPE) is involved in retinal degeneration, mostly in the course of age-related macular degeneration (AMD), which is an increasingly prevalent retinal disorder, eventually leading to blindness. However, most autophagy activators own serious adverse effects when administered systemically. Curcumin is a phytochemical, which induces autophagy with a wide dose-response curve, which brings minimal side effects. Recent studies indicating defective autophagy in AMD were analyz...
Source: Current Neuropharmacology - July 6, 2023 Category: Drugs & Pharmacology Authors: Roberto Pinelli Michela Ferrucci Francesca Biagioni Violet Bumah Elena Scaffidi Stefano Puglisi-Allegra Francesco Fornai Source Type: research
Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration
Curr Neuropharmacol. 2023 Jul 5. doi: 10.2174/1570159X21666230705103839. Online ahead of print.ABSTRACTDefective autophagy in the retinal pigment epithelium (RPE) is involved in retinal degeneration, mostly in the course of age-related macular degeneration (AMD), which is an increasingly prevalent retinal disorder, eventually leading to blindness. However, most autophagy activators own serious adverse effects when administered systemically. Curcumin is a phytochemical, which induces autophagy with a wide dose-response curve, which brings minimal side effects. Recent studies indicating defective autophagy in AMD were analyz...
Source: Current Neuropharmacology - July 6, 2023 Category: Drugs & Pharmacology Authors: Roberto Pinelli Michela Ferrucci Francesca Biagioni Violet Bumah Elena Scaffidi Stefano Puglisi-Allegra Francesco Fornai Source Type: research
Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration
Curr Neuropharmacol. 2023 Jul 5. doi: 10.2174/1570159X21666230705103839. Online ahead of print.ABSTRACTDefective autophagy in the retinal pigment epithelium (RPE) is involved in retinal degeneration, mostly in the course of age-related macular degeneration (AMD), which is an increasingly prevalent retinal disorder, eventually leading to blindness. However, most autophagy activators own serious adverse effects when administered systemically. Curcumin is a phytochemical, which induces autophagy with a wide dose-response curve, which brings minimal side effects. Recent studies indicating defective autophagy in AMD were analyz...
Source: Current Neuropharmacology - July 6, 2023 Category: Drugs & Pharmacology Authors: Roberto Pinelli Michela Ferrucci Francesca Biagioni Violet Bumah Elena Scaffidi Stefano Puglisi-Allegra Francesco Fornai Source Type: research
Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration
Curr Neuropharmacol. 2023 Jul 5. doi: 10.2174/1570159X21666230705103839. Online ahead of print.ABSTRACTDefective autophagy in the retinal pigment epithelium (RPE) is involved in retinal degeneration, mostly in the course of age-related macular degeneration (AMD), which is an increasingly prevalent retinal disorder, eventually leading to blindness. However, most autophagy activators own serious adverse effects when administered systemically. Curcumin is a phytochemical, which induces autophagy with a wide dose-response curve, which brings minimal side effects. Recent studies indicating defective autophagy in AMD were analyz...
Source: Current Neuropharmacology - July 6, 2023 Category: Drugs & Pharmacology Authors: Roberto Pinelli Michela Ferrucci Francesca Biagioni Violet Bumah Elena Scaffidi Stefano Puglisi-Allegra Francesco Fornai Source Type: research
Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration
Curr Neuropharmacol. 2023 Jul 5. doi: 10.2174/1570159X21666230705103839. Online ahead of print.ABSTRACTDefective autophagy in the retinal pigment epithelium (RPE) is involved in retinal degeneration, mostly in the course of age-related macular degeneration (AMD), which is an increasingly prevalent retinal disorder, eventually leading to blindness. However, most autophagy activators own serious adverse effects when administered systemically. Curcumin is a phytochemical, which induces autophagy with a wide dose-response curve, which brings minimal side effects. Recent studies indicating defective autophagy in AMD were analyz...
Source: Current Neuropharmacology - July 6, 2023 Category: Drugs & Pharmacology Authors: Roberto Pinelli Michela Ferrucci Francesca Biagioni Violet Bumah Elena Scaffidi Stefano Puglisi-Allegra Francesco Fornai Source Type: research
Curcumin as a Perspective Protection for Retinal Pigment Epithelium during Autophagy Inhibition in the Course of Retinal Degeneration
Curr Neuropharmacol. 2023 Jul 5. doi: 10.2174/1570159X21666230705103839. Online ahead of print.ABSTRACTDefective autophagy in the retinal pigment epithelium (RPE) is involved in retinal degeneration, mostly in the course of age-related macular degeneration (AMD), which is an increasingly prevalent retinal disorder, eventually leading to blindness. However, most autophagy activators own serious adverse effects when administered systemically. Curcumin is a phytochemical, which induces autophagy with a wide dose-response curve, which brings minimal side effects. Recent studies indicating defective autophagy in AMD were analyz...
Source: Current Neuropharmacology - July 6, 2023 Category: Drugs & Pharmacology Authors: Roberto Pinelli Michela Ferrucci Francesca Biagioni Violet Bumah Elena Scaffidi Stefano Puglisi-Allegra Francesco Fornai Source Type: research
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion
Platelets and erythrocytes constitute over 95% of all hematopoietic stem cell output. However, the clonal dynamics of HSC contribution to these lineages remains largely unexplored. (Source: Genome Biology)
Source: Genome Biology - June 27, 2023 Category: Genetics & Stem Cells Authors: Edyta E. Wojtowicz, Jayna J. Mistry, Vladimir Uzun, Charlotte Hellmich, Anita Scoones, Desmond W. Chin, Laura M. Kettyle, Francesca Grasso, Allegra M. Lord, David J. Wright, Graham J. Etherington, Petter S. Woll, Mirjam E. Belderbos, Kristian M. Bowles, C Tags: Research Source Type: research
Weight-based Discrimination Linked to Disordered Eating in Sexual Minority Young Adults
Three in ten young adults who identify as members of sexual minorities experience weight-based discrimination and may have a higher risk of disordered eating behaviors as a result, a study in the International Journal of Eating Disorders has found.“Overall, given the elevated risk of [disordered eating behaviors] among sexual minority adolescents and young adults, the effects of weight-based discrimination must be considered when developing eating disorders prevention efforts and effective clinical care for this underserved population,” w rote Allegra R. Gordon, Sc.D., M.P.H., of Boston University School of Public Heal...
Source: Psychiatr News - June 26, 2023 Category: Psychiatry Tags: Allegra Gordon binge eating Everyday Discrimination Scale overeating sexual minorities U.S. Growing Up Today Study weight-based discrimination Source Type: research
