Solubility Enhancement of Fexofenadine using Self-Nano emulsifying Drug Delivery System for improved biomimetic attributes
Conclusion: Thus, the investigation revealed that, the L-SNEDDs incorporated fexofenadine was most effective with a mixture of surfactant and co-surfactant with improved solubility intend to relieve pain associated with inflammation with single-dose oral administration.PMID:37832935 | DOI:10.1016/j.pharma.2023.10.003 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 13, 2023 Category: Drugs & Pharmacology Authors: Popat Mohite Anjali Joshi Sudarshan Singh Bhupendra Prajapati Source Type: research

Solubility Enhancement of Fexofenadine using Self-Nano emulsifying Drug Delivery System for improved biomimetic attributes
Conclusion: Thus, the investigation revealed that, the L-SNEDDs incorporated fexofenadine was most effective with a mixture of surfactant and co-surfactant with improved solubility intend to relieve pain associated with inflammation with single-dose oral administration.PMID:37832935 | DOI:10.1016/j.pharma.2023.10.003 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 13, 2023 Category: Drugs & Pharmacology Authors: Popat Mohite Anjali Joshi Sudarshan Singh Bhupendra Prajapati Source Type: research

Solubility Enhancement of Fexofenadine using Self-Nano emulsifying Drug Delivery System for improved biomimetic attributes
Conclusion: Thus, the investigation revealed that, the L-SNEDDs incorporated fexofenadine was most effective with a mixture of surfactant and co-surfactant with improved solubility intend to relieve pain associated with inflammation with single-dose oral administration.PMID:37832935 | DOI:10.1016/j.pharma.2023.10.003 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 13, 2023 Category: Drugs & Pharmacology Authors: Popat Mohite Anjali Joshi Sudarshan Singh Bhupendra Prajapati Source Type: research

The Shift to Synthetics: A Review of Novel Synthetic Matrices for Wound Closure
Surg Technol Int. 2023 Oct 7;42:sti42/1711. Online ahead of print.ABSTRACTSince the late 1990s, a growing number of "skin substitutes" have become available to practitioners seeking to heal large surface wounds. These extracellular matrices were originally from xenograft sources, and then from very highly engineered living human cellular tissues. More recently, they consist of biosynthetic materials that are combinations of silicone, collagen and chondroitin. The list of xenograft materials as well as minimally manipulated human tissues, such as human skin-, amniotic- and placental-based products, has grown exponentially. ...
Source: Surgical Technology International - October 6, 2023 Category: Surgery Authors: Callie P Horn Allegra L Fierro John C Lantis Source Type: research

AI tools as science policy advisers? The potential and the pitfalls
Nature, Published online: 27 September 2023; doi:10.1038/d41586-023-02999-3Large language models and other artificial-intelligence systems could be excellent at synthesizing scientific evidence for policymakers — but only with appropriate safeguards and humans in the loop. (Source: Nature AOP)
Source: Nature AOP - September 27, 2023 Category: Research Authors: Chris Tyler K. L. Akerlof Alessandro Allegra Zachary Arnold Henriette Canino Marius A. Doornenbal Josh A. Goldstein David Budtz Pedersen William J. Sutherland Source Type: research

Stereotactic Body Radiation Therapy and Abiraterone Acetate for Patients Affected by Oligometastatic Castrate-Resistant Prostate Cancer: A Randomized Phase II Trial (ARTO)
CONCLUSION: The trial reached its primary end point of biochemical control and PFS, suggesting a clinical advantage for SBRT in addition to first-line AAP treatment in patients with metastatic castration-resistant prostate cancer.PMID:37733977 | DOI:10.1200/JCO.23.00985 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Giulio Francolini Andrea Gaetano Allegra Beatrice Detti Vanessa Di Cataldo Saverio Caini Alessio Bruni Gianluca Ingrosso Rolando Maria D'Angelillo Anna Rita Alitto Matteo Augugliaro Luca Triggiani Silvana Parisi Gaetano Facchini Marco Banini Gabriele Simo Source Type: research

Stereotactic Body Radiation Therapy and Abiraterone Acetate for Patients Affected by Oligometastatic Castrate-Resistant Prostate Cancer: A Randomized Phase II Trial (ARTO)
CONCLUSION: The trial reached its primary end point of biochemical control and PFS, suggesting a clinical advantage for SBRT in addition to first-line AAP treatment in patients with metastatic castration-resistant prostate cancer.PMID:37733977 | DOI:10.1200/JCO.23.00985 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Giulio Francolini Andrea Gaetano Allegra Beatrice Detti Vanessa Di Cataldo Saverio Caini Alessio Bruni Gianluca Ingrosso Rolando Maria D'Angelillo Anna Rita Alitto Matteo Augugliaro Luca Triggiani Silvana Parisi Gaetano Facchini Marco Banini Gabriele Simo Source Type: research