"This drug turned me into a robot": an actor-network analysis of a web-based ethnographic study of psychostimulant use.
CONCLUSION: These findings may contribute to shaping public health policies and interventions that acknowledge the values of the individuals they seek to help, and that attempt to reduce the potential harms associated with these pharmaceuticals as an alternative to more prohibitive approaches.
PMID: 30465287 [PubMed - as supplied by publisher] (Source: Canadian Journal of Public Health)
Source: Canadian Journal of Public Health - November 21, 2018 Category: International Medicine & Public Health Authors: Robitaille C Tags: Can J Public Health Source Type: research
Enhancing the Nature-of-Activities Account of Enhancement
AbstractMany find it intuitive that those who use enhancements like steroids and Adderall in Olympic weightlifting and education are due less praise than those who perform equally well without using these enhancements. Nonetheless, it is not easy to coherently explain why one might be justifiably due less praise for using these technologies to enhance one ’s performance. Justifications for this intuition which rely on concerns regarding authenticity, cheating, or shifts in who is responsible for the performance face serious problems. Santoni de Sio et al., however, have recently defended a justification for this intuitio...
Source: Neuroethics - October 1, 2018 Category: Medical Ethics Source Type: research
Caffeine-Induced Psychosis in a Bodybuilder With Chronic Testosterone and Amphetamine/Dextroamphetamine Misuse.
Authors: Gomes CAB, Mahgoub Y
PMID: 29947481 [PubMed - in process] (Source: The Primary Care Companion for CNS Disorders)
Source: The Primary Care Companion for CNS Disorders - June 29, 2018 Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
Using drug knowledgebase information to distinguish between look-alike-sound-alike drugs
ConclusionsDrug indications data from a drug knowledgebase can discriminate between many LASA drugs. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 22, 2018 Category: Information Technology Source Type: research
Enhancing the Nature-of-Activities Account of Enhancement
AbstractMany find it intuitive that those who use enhancements like steroids and Adderall in Olympic weightlifting and education are due less praise than those who perform equally well without using these enhancements. Nonetheless, it is not easy to coherently explain why one might be justifiably due less praise for using these technologies to enhance one ’s performance. Justifications for this intuition which rely on concerns regarding authenticity, cheating, or shifts in who is responsible for the performance face serious problems. Santoni de Sio et al., however, have recently defended a justification for this intuitio...
Source: Neuroethics - May 3, 2018 Category: Medical Ethics Source Type: research
Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research
Placental Complications Associated With Psychostimulant Use in Pregnancy.
CONCLUSION: Psychostimulant use during pregnancy was associated with a small increased relative risk of preeclampsia and preterm birth. The absolute increases in risks are small and, thus, women with significant ADHD should not be counseled to suspend their ADHD treatment based on these findings.
PMID: 29112657 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 3, 2017 Category: OBGYN Authors: Cohen JM, Hernández-Díaz S, Bateman BT, Park Y, Desai RJ, Gray KJ, Patorno E, Mogun H, Huybrechts KF Tags: Obstet Gynecol Source Type: research
Discordant reporting of nonmedical amphetamine use among Adderall-using high school seniors in the US
(Source: Drug and Alcohol Dependence)
Source: Drug and Alcohol Dependence - October 20, 2017 Category: Addiction Authors: Joseph J. Palamar, Austin Le Tags: Short communication Source Type: research
22.5 Animal Models and Amphetamine Isomers in Attention-Deficit/Hyperactivity Drug Development
Psychostimulants with different isomers of amphetamine, such as Adderall and d-amphetamine, are known to be safe and effective treatments for ADHD. Clinical studies have demonstrated that l-amphetamine is not an inactive isomer. Adderall contains approximately 25 percent l-amphetamine; Evekeo ® contains approximately 50 percent l-amphetamine. Clinical studies and animal models have suggested that there may be a role for different isomer combinations of amphetamine based on the patient’s diagnosis and genetic makeup. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2017 Category: Psychiatry Authors: Paul E.A. Glaser Source Type: research
Extended-Release ADHD Drug
Another extended-release amphetamine-dextroamphetamine combination medication has receivedapproval for the treatment of attention-deficit/hyperactivity disorder (ADHD). Marketed as Mydayis, the drug is indicated for teens and adults. Children aged 12 years or younger should not take the drug. (Source: JAMA)
Source: JAMA - August 1, 2017 Category: General Medicine Source Type: research
Adderall might improve your test scores – but so could a placebo
Some students take ADHD drugs to improve their academic performance. A trial suggests Adderall can work in this way, but it ’s largely due to the placebo effect (Source: New Scientist - Health)
Source: New Scientist - Health - July 20, 2017 Category: Consumer Health News Source Type: research
Patient-relevant outcomes associated with generic tamsulosin, levothyroxine and amphetamine in the FDA Adverse Event Reporting System: a pilot study.
CONCLUSION: FAERS reveals several domains of patient-relevant concerns associated with generic drugs.
PMID: 28686057 [PubMed - as supplied by publisher] (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - July 8, 2017 Category: General Medicine Tags: J Comp Eff Res Source Type: research
Posterior reversible leukoencephalopathy syndrome after kratom ingestion.
We report a young man who suddenly developed severe headache, disorientation, and aphasia following ingestion of kratom and Adderall. Computed tomography and magnetic resonance imaging of his head revealed foci of vasogenic edema in the posterior occipital lobes, frontal lobes, and brainstem. In addition, he had a small area of hemorrhage in the left posterior occipital lobe. Lumbar puncture revealed an increased number of red blood cells but no other abnormalities. His initial blood pressure was elevated but returned to normal during hospitalization. This case suggests that kratom can cause posterior reversible encephalop...
Source: Baylor University Medical Center Proceedings - July 1, 2017 Category: Universities & Medical Training Authors: Castillo A, Payne JD, Nugent K Tags: Proc (Bayl Univ Med Cent) Source Type: research
An Algorithm to Identify Generic Drugs in the FDA Adverse Event Reporting System
ConclusionsThe algorithm demonstrated high inter-rater reliability with moderate internal consistency for identifying generic drugs in the FAERS, in our sample. Future efforts should focus on improving the reliability and validity of identifying generics through improving the completeness of reporting in the FAERS. (Source: Drug Safety)
Source: Drug Safety - June 7, 2017 Category: Drugs & Pharmacology Source Type: research
Substance Use Among Transgender Students in California Public Middle and High Schools
CONCLUSIONSThe study's findings indicate a need for community‐ and school‐based interventions that reduce substance use among transgender youth. (Source: Journal of School Health)
Source: Journal of School Health - April 6, 2017 Category: Health Management Authors: Kris Tunac De Pedro, Tamika D. Gilreath, Christopher Jackson, Monica Christina Esqueda Tags: RESEARCH ARTICLE Source Type: research
