Extended-Release ADHD Drug

Another extended-release amphetamine-dextroamphetamine combination medication has receivedapproval for the treatment of attention-deficit/hyperactivity disorder (ADHD). Marketed as Mydayis, the drug is indicated for teens and adults. Children aged 12 years or younger should not take the drug.
Source: JAMA - Category: General Medicine Source Type: research

Related Links:

Publication date: Available online 10 November 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Alessio Bellato, Iti Arora, Chris Hollis, Madeleine J. GroomAbstractAlthough arousal mechanisms have frequently been found to be atypical in ADHD, these findings usually emerged from indirect behavioural measures which give only a limited understanding of arousal dysregulation in this condition. To assess the hypothesis that functioning of the autonomic nervous system (ANS), one component of arousal, is atypical in ADHD, we carried out a systematic review of the literature on 55 studies investigating electro-dermal,...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
In this study, we proposed a dynamical systems perspective to assess how the DMN over time recruits different configurations of network segregation and integration. Specifically, we were interested in configurations for which both intra- and inter-network connections are retained, as opposed to commonly used methods which assess network segregation as a single measure. From resting-state fMRI data, we extracted three different stable configurations of FC patterns for the DMN, namely synergies. We provided evidence supporting our hypothesis that ADHD differs compared to controls, both in terms of recruitment rate and topolo...
Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: Available online 7 November 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Yan Zeng, Ying Tang, Yan Yue, Wenxing Li, Xia Qiu, Peng Hu, Jun Tang, Huiqing Wang, Xiaoyan Yang, Yi Qu, Dezhi MuAbstractWe conducted a systematic review and meta-analysis to evaluate the association between parental diabetes mellitus and the risk of ADHD in offspring. The PubMed, EMBASE, Cochrane, and Web of Science databases were searched from inception to May 31, 2019. Thirteen observational studies containing 5,052,736 participants were included. Two reviewers independently extracted data and assessed the quality...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Few if any experts believe that existing psychiatric diagnostic categories included in the DSM/ICD are actually discrete disease entities. Attention-deficit/hyperactivity disorder (ADHD) is emblematic of the problems in the existing psychiatric classification system. ADHD symptoms reliably cluster into two correlated dimensions in factor analysis. However, children with ADHD vary considerably in their symptom profiles, symptom trajectories, clinical outcomes, and biological and psychological correlates.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Review Source Type: research
While there are a number of drugs to treat Attention Deficit Hyperactivity Disorder (ADHD), they can have some pretty serious side effects. Researchers in Singapore at the country’s Institute of Mental Health (IMH), Duke-NUS (National Universit...
Source: Medgadget - Category: Medical Devices Authors: Tags: Neurology Pediatrics Psychiatry Source Type: blogs
This study aims to analyze the effect of stimulant on processing speed performance and attention indices in children with ASD and ADHD.Methods: Forty children aged 6-18 years diagnosed with ASD who also met the criteria for ADHD were recruited. All children performed a computerized performance test for the assessment of cognitive attention performance three times: twice while they are drug naïve and once an hour after taking a single dose of 10 mg. methylphenidate (MPH). This performance was compared to a group of children diagnosed with 'ADHD only' without ASD.Results: A significant difference (p 
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
[Neurobehavioral Comorbidities in Pentylenetetrazol-kindled Mice and Role of the α4β2 Nicotinic Acetylcholine Receptor]. Yakugaku Zasshi. 2019;139(11):1397-1402 Authors: Takechi K Abstract Patients with epilepsy are often affected by not only seizures but also a variety of cognitive and psychiatric comorbidities that further impair their quality of life. However, it is unclear whether epilepsy is associated with psychic function. The aim of the present study was to clarify the effects of kindling-induced epileptic seizures on psychic functioning, using behavioral pharmacological tests. Pent...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - Category: Drugs & Pharmacology Authors: Tags: Yakugaku Zasshi Source Type: research
Abstract Over the last decade there has been an increase in the prevalence of autism spectrum disorder (ASD); however, its pathogenic mechanisms remain unclear. To date, no effective drug has been developed to treat the core symptoms of ASD, especially social interaction deficits. Previous studies have mainly focused on the glutamatergic, GABAergic, and serotonergic signaling pathways; however, a growing number of studies have reported abnormalities in the dopaminergic pathway, such as mutations and functional alterations of dopamine-related molecules, in ASD patients. Furthermore, atypical antipsychotic drugs ris...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - Category: Drugs & Pharmacology Authors: Tags: Yakugaku Zasshi Source Type: research
Source: Neuropsychiatric Disease and Treatment - Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research
ConclusionThis study provides insights into parents’ perceptions regarding an integrated intervention approach for early stuttering and behavior management. It also indicates how adopting a holistic approach to stuttering intervention is positive and has social validity.
Source: Journal of Fluency Disorders - Category: Speech-Language Pathology Source Type: research
More News: Adderall | ADHD | Amphetamine | Children | General Medicine | Hyperactivity