Injectable Thermoresponsive Gels Offer Sustained Dual Release of Bupivacaine Hydrochloride and Ketorolac Tromethamine For Up To Two Weeks
Publication date: Available online 26 May 2021Source: International Journal of PharmaceuticsAuthor(s): Hani Abdeltawab, Darren Svirskis, Ben J Boyd, Andrew Hill, Manisha Sharma (Source: International Journal of Pharmaceutics)
Source: International Journal of Pharmaceutics - May 30, 2021 Category: Drugs & Pharmacology Source Type: research
Pre-Emptive Topical Ketorolac Tromethamine 0.5% for Panretinal Photocoagulation
Journal of Ocular Pharmacology and Therapeutics, Ahead of Print. (Source: Journal of Ocular Pharmacology and Therapeutics)
Source: Journal of Ocular Pharmacology and Therapeutics - April 1, 2021 Category: Opthalmology Authors: Joanne Shalini Chewa Raja Sujaya Singh Fazliana Ismail Source Type: research
Drugs for Allergic Rhinitis and Allergic Conjunctivitis
Date: April 19, 2021
Issue #:
1622Summary:
The choice of drugs for treatment of allergic rhinitis
depends on the severity of symptoms and whether
they are are intermittent or persistent (see Table 1). (Source: The Medical Letter)
Source: The Medical Letter - March 24, 2021 Category: Drugs & Pharmacology Authors: admin Tags: Acular Aerius Afrin Alavert Alaway Alcaftadine Allegra Allergic rhinitis Alocril Alomide Antihistamines Avamys azelastine azelastine/fluticasone propionate Beclomethasone dipropionate Beconase AQ Benadryl Bepotastine Be Source Type: research
Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia
In conclusion, intramuscular injection of nalbuphine 30 min before trigeminal ganglion pulse radiofrequency surgery can be conducive to pain relief and improve the postoperative comfort of patients, providing an effective alternative for the alleviation of PHN in clinic.PMID:33747319 | PMC:PMC7943312 | DOI:10.1155/2021/6623112 (Source: Pain Research and Management)
Source: Pain Research and Management - March 22, 2021 Category: Anesthesiology Authors: Song Wen Qiu-Xia Xiao Zhao-Qiong Zhu Li Chen Ying Li Qi-Hua Ran Song Cao Liu-Lin Xiong Source Type: research
Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia
In conclusion, intramuscular injection of nalbuphine 30 min before trigeminal ganglion pulse radiofrequency surgery can be conducive to pain relief and improve the postoperative comfort of patients, providing an effective alternative for the alleviation of PHN in clinic.PMID:33747319 | PMC:PMC7943312 | DOI:10.1155/2021/6623112 (Source: Pain Research and Management)
Source: Pain Research and Management - March 22, 2021 Category: Anesthesiology Authors: Song Wen Qiu-Xia Xiao Zhao-Qiong Zhu Li Chen Ying Li Qi-Hua Ran Song Cao Liu-Lin Xiong Source Type: research
Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia
In conclusion, intramuscular injection of nalbuphine 30 min before trigeminal ganglion pulse radiofrequency surgery can be conducive to pain relief and improve the postoperative comfort of patients, providing an effective alternative for the alleviation of PHN in clinic.PMID:33747319 | PMC:PMC7943312 | DOI:10.1155/2021/6623112 (Source: Pain Research and Management)
Source: Pain Research and Management - March 22, 2021 Category: Anesthesiology Authors: Song Wen Qiu-Xia Xiao Zhao-Qiong Zhu Li Chen Ying Li Qi-Hua Ran Song Cao Liu-Lin Xiong Source Type: research
Nano-engineering of ketorolac tromethamine platforms for ocular treatment of inflammatory disorders
Nanomedicine, Ahead of Print. (Source: Nanomedicine)
Source: Nanomedicine - February 15, 2021 Category: Nanotechnology Authors: Mireia Mallandrich Ana C Calpena Beatriz Clares Alexander Parra Mar ía L García Jos é L. Soriano Francisco Fern ández-Campos Source Type: research
Nano-engineering of ketorolac tromethamine platforms for ocular treatment of inflammatory disorders
Nanomedicine, Ahead of Print. (Source: Future Medicine: Nanomedicine)
Source: Future Medicine: Nanomedicine - February 15, 2021 Category: Nanotechnology Authors: Mireia Mallandrich Ana C Calpena Beatriz Clares Alexander Parra Mar ía L García Jos é L. Soriano Francisco Fern ández-Campos Source Type: research
Effects of topical instillation of 0.1% diclofenac sodium, 0.5% ketorolac tromethamine, and 0.03% flurbiprofen sodium on corneal sensitivity in ophthalmologically normal cats.
CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that neither short-term nor prolonged topical instillation of 3 NSAID ophthalmic solutions had any effect on the CS of healthy cats. Given potential differences in cyclooxygenase expression between healthy and diseased eyes, further investigation of the effects of topical NSAID instillation in the eyes of cats with ocular surface inflammation is warranted.
PMID: 33369491 [PubMed - as supplied by publisher] (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - December 29, 2020 Category: Veterinary Research Authors: Roberts JK, Meekins JM, Roush JK, Rankin AJ Tags: Am J Vet Res Source Type: research
The role of the endothelium in the hyperemic response to passive leg movement: looking beyond nitric oxide.
Abstract
Passive leg movement (PLM) evokes a robust and predominantly nitric oxide (NO)-mediated increase in blood flow that declines with age and disease. Consequently, PLM is becoming increasingly accepted as a sensitive assessment of endothelium-mediated vascular function. However, a substantial PLM-induced hyperemic response is still evoked despite NO synthase (NOS) inhibition. Therefore, in 9 young healthy men (25±4 yrs), this investigation aimed to determine if the combination of two potent endothelium-dependent vasodilators, specifically prostaglandin (PG) and endothelium-derived hyperpolarizing fa...
Source: American Journal of Physiology. Heart and Circulatory Physiology - December 11, 2020 Category: Physiology Authors: Trinity JD, Kwon OS, Broxterman RM, Gifford JR, Kithas AC, Hydren JR, Jarrett CL, Shields KL, Bisconti AV, Park SH, Craig JC, Nelson AD, Morgan DE, Jessop JE, Bledsoe AD, Richardson RS Tags: Am J Physiol Heart Circ Physiol Source Type: research
Is Dexamethasone superior to Ketorolac in reducing pain, swelling and trismus following mandibular third molar removal? A split mouth triple-blind randomized clinical trial.
CONCLUSIONS: The clinical performance of dexamethasone in controlling pain, swelling and trismus after mandibular third molar removal was superior to ketorolac tromethamine's.
PMID: 33247572 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - November 29, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research
Ketorolac tromethamine pretreatment suppresses sufentanil-induced cough during general anesthesia induction: a prospective randomized controlled trial
To observe the effect of pretreatment with ketorolac tromethamine on sufentanil-induced cough in general anesthesia patients. (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - August 17, 2020 Category: Anesthesiology Authors: Zhen Tian, Bei Hu, Min Miao, Lulu Zhang, Lin Wang and Bin Chen Tags: Research article Source Type: research
Cetirizine Ophthalmic Solution (Zerviate) for Allergic Conjunctivitis
Date: June 1, 2020
Issue #:
1599Summary:
A 0.24% ophthalmic solution of the second-generation
H1-antihistamine cetirizine (Zerviate– Eyevance) is now
available by prescription for treatment of ocular itching
associated with allergic conjunctivitis in patients ≥2
years old. Oral cetirizine (Zyrtec, and others), which is
used for treatment of allergic conjunctivitis and rhinitis,
has been available over the counter (OTC) for years. (Source: The Medical Letter)
Source: The Medical Letter - April 29, 2020 Category: Drugs & Pharmacology Authors: admin Tags: Acular Alaway Alcaftadine Allergic rhinitis Alocril Alomide nedocromil Antihistamines azelastine Bepotastine Bepreve cetirizine Clear Eyes Conjunctivitis corticosteroids Cromolyn Epinastine Ketorolac Ketotifen Lastacaft Source Type: research
Effective mamagement of acute postoperative pain using intravenous emulsions of novel ketorolac prodrugs: in vitro and in vivo evaluations.
EFFECTIVE MAMAGEMENT OF ACUTE POSTOPERATIVE PAIN USING INTRAVENOUS EMULSIONS OF NOVEL KETOROLAC PRODRUGS: IN VITRO AND IN VIVO EVALUATIONS.
Eur J Pharm Sci. 2020 Apr 17;:105344
Authors: Niu B, Yin Z, Qiu N, Yu Y, Huang Q, Zhu Q, Zhuang X, Chen Y
Abstract
The aim was to prepare intravenous fat emulsions (IFEs) of ketorolac (KTL) ester prodrugs and to investigate the pharmacokinetics and pharmacodynamics of these formulations. Three prodrugs of KTL (KTL-IS, KTL-AX and KTL-BT) were synthesized as a means to increase the lipid solubility of KTL. All KTL prodrugs with higher Log P valu...
Source: European Journal of Pharmaceutical Sciences - April 16, 2020 Category: Drugs & Pharmacology Authors: Niu B, Yin Z, Qiu N, Yu Y, Huang Q, Zhu Q, Zhuang X, Chen Y Tags: Eur J Pharm Sci Source Type: research
Randomized, Double-Blind, Placebo-Controlled Study to Compare the Efficacy of Combination of Lidocaine with Ketorolac or Triamcinolone versus Lidocaine Alone for Soft Tissue Injuries
Conclusionsketorolac was considered equal to triamcinolone. (Source: Journal of Orthopaedics)
Source: Journal of Orthopaedics - January 28, 2020 Category: Orthopaedics Source Type: research
