Analyses of odontogenic tumours: the most recent classification proposed by the World Health Organization (2017).
CONCLUSIONS: The new odontogenic tumour list has been simplified with the objective of improving its role as an international guide for diagnosis. Some changes have been possible thanks to the application of immunohistochemistry and molecular genetic techniques that allow better characterization of certain tumours. Further clinicopathological and molecular studies are needed so that this new classification can be consolidated and/or amended. PMID: 32388513 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Validation of the oral health impact profile - 14 in patients with head and neck cancer.
Authors: Tesic M, Cankovic M, Jevtic M, Stevanovic D Abstract BACKGROUND: The Oral Health Impact Profile-14 (OHIP-14) was designed to assess patients' perception of the impact of oral disorders on their quality of life (QoL). Although the OHIP-14 is now frequently used in patients with head and neck cancer, data related to its measurement properties in this population are scarce. The aim of the present study was to evaluate the reliability and validity of the OHIP-14 in a sample of Serbian patients with head and neck cancer. MATERIAL AND METHODS: Data were available for 345 patients (257 [74.5%] males; aged 30-...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Cardiovascular diseases and apical periodontitis: association not always implies causality.
CONCLUSIONS: The results are inconsistent and a causal relationship between CVDS and endodontic disease cannot be stablished. The risk factors common to both diseases can act as confounding factors, biasing the results. To reach definitive conclusions about the type of association (causal or non-causal) between both diseases, longitudinal epidemiological studies must be carried out to establish the temporal relationship and the dose-response gradient. PMID: 32388515 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Comparative expression of cyclooxygenase 2 and Ki67 in amelanotic and conventional oral melanomas.
In this study, we have compared the expression of COX-2 and Ki67 in a series of amelanotic (n=7) and melanotic oral melanomas (n=22). The cases were selected from 4 pathology laboratories and submitted to the immunohistochemical (IHC) reactions. We analyzed the IHC staining based on a qualitative - using visual scores; and a computer-assisted method (quantitative) using scanned slides and software for digital analysis. RESULTS: COX-2 was expressed in all oral melanomas; however, its intensity was significantly higher in the amelanotic ones (P
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Incidence of traumatic dental injury in Valencia, Spain.
Authors: Faus-Matoses V, Faus-Matoses I, Ruiz-Sánchez C, Faus-Damiá M, Faus-Llácer VJ Abstract BACKGROUND: While traumatic dental injuries (TDI) are an increasingly frequent occurrence in everyday dental practice, little research on TDIs has been published in Spain. The aim of this study was to determine the incidence of TDIs in a population in Valencia (Spain) and investigate influential variables. In addition, a protocol for TDI data collection is proposed. MATERIAL AND METHODS: This retrospective study compiled data from patients attending a private dental clinic between January 2003 and...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Quality assessment of randomized controlled trial abstracts on drug therapy of periodontal disease from the abstracts published in dental Science Citation Indexed journals in the last ten years.
This study evaluated the reporting quality of RCT abstracts on drug therapy of periodontal disease and assessed the associated factors. MATERIAL AND METHODS: The Pubmed database was searched for periodontal RCTs published in Science Citation Indexed (SCI) dental journals from 2010/01/01 to 2019/07/17. Information was extracted from the abstracts according to a modified Consolidated Standards of Reporting Trials (CONSORT) guideline checklist. The data was analyzed using descriptive statistical analysis and the statistical associations were examined using the linear regression analysis (P
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Clinicopathological and prognostic characterization of oral lichenoid disease and its main subtypes: A series of 384 cases.
CONCLUSIONS: OLD is a potentially malignant disorder of the oral mucosa which has to be correctly diagnosed as either OLP or OLL, since the risk of malignancy of these subtypes is significantly different. PMID: 32388519 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Myofibroblasts and increased angiogenesis contribute to periapical cystic injury containment and repair.
Authors: de-Freitas CT, de-França GM, Gordón-Núñez MA, Santos PP, de-Lima KC, Galvão HC Abstract BACKGROUND: Myofibroblasts (MF) and angiogenesis are important factors in the development and expansion of cystic lesions, where these cells secrete growth factors and proteases, stimulating angiogenesis, matrix deposition and cell migration, affecting the growth of these periapicopathies. The present study aimed to evaluate the immunohistochemical expression of CD34 and α-SMA in radicular cysts (RC) and residual radicular cysts (RRC), with the purpose of contributing to a better...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Short time guided bone regeneration using beta-tricalcium phosphate with and without fibronectin - An experimental study in rats.
Authors: Sánchez-Garcés MÁ, Camps-Font O, Escoda-Francolí J, Muñoz-Guzón F, Toledano-Serrabona J, Gay-Escoda C Abstract BACKGROUND:  The aim of this histomorphometric study was to assess the bone regeneration potential of beta-tricalcium phosphate with fibronectin (β-TCP-Fn) in critical-sized defects (CSDs) in rats calvarial, to know whether Fn improves the new bone formation in a short time scope. MATERIAL AND METHODS:  CSDs were created in 30 Sprague Dawley rats, and divided into four groups (2 or 6 weeks of healing) and type of filling (β-TCP...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Photobiomodulation therapy for the management of recurrent aphthous stomatitis in children: clinical effectiveness and parental satisfaction.
This study aims to evaluate the effectiveness of the photobiomodulation therapy (PBMT) in the treatment of minor recurrent aphthous stomatitis (MiRAS) in children, in terms of pain relief, lesion size reduction and the parental satisfaction of the therapy. MATERIAL AND METHODS: This randomized controlled study was carried out on 60 children with clinical diagnosis of MiRAS. Patients were randomized into two groups: group A receiving laser therapy and group B receiving sham therapy (placebo). Laser therapy (diode laser, λ: 645 nm) was administered on day 1 (T0) for three consecutive days. Patients were evaluated ...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Quality and readability of the dental information obtained by patients on Internet: criteria for selecting medical consultation websites.
Authors: Allegue-Magaz S, Peñarrocha-Diago M, Chamorro-Petronacci CM, Lorenzo-Pouso AI, Blanco-Carrión A, García-García A, Pérez-Sayáns M Abstract BACKGROUND: The main objective of this study is to examine the quality of the information available for patients online with regards to the apicoectomy surgical procedure, both on general and critically selected websites. The hypothesis is that general websites has less quality than other that have been pre-selected. MATERIAL AND METHODS: A search for the English term "apicoectomy" was performed online. The first 10...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Epidemiologic analysis of salivary gland tumors over a 10-years period diagnosed in a northeast Brazilian population.
Authors: Cunha JL, Coimbra AC, Silva JV, Nascimento IS, Andrade ME, Oliveira CR, Almeida OP, Soares CD, Sousa SF, Albuquerque-Júnior RL Abstract BACKGROUND: Salivary gland tumors (SGT) correspond to a heterogeneous group of lesions with variable biological behavior. The present study aimed to determine the distribution and demographic findings of salivary gland neoplasms in a northeast Brazilian population. MATERIAL AND METHODS: A retrospective descriptive cross-sectional study was performed. A total of 588 cases of SGT were diagnosed between 2006 and 2016 of 4 pathology services in the state of Sergipe,...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Effect of different solutions in reversing the damage caused by radiotherapy in dentin structure.
This study evaluated the effect of different solutions on the dentin chemical composition and collagen structure of irradiated dentin. MATERIAL AND METHODS: Sixty maxillary canines were distributed in 2 groups (n=30): non-irradiated and irradiated (radiotherapy: X-rays of 6 MV in 30 cycles of 2 Gy to 60 Gy). The teeth were sectioned, sanded, and polished to obtain 3x3x2 mm fragments, which were redistributed in 3 subgroups (n=10) according to the treatment employed: chlorhexidine 2% (CL), chitosan 0.2% (QT), and 0.5 M carbodiimide (EDC). The samples were analyzed in FTIR at time zero (T0-control) and after 1 (T1), 3 (T...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

High frequency of BRAF V600E mutation in Iranian population ameloblastomas.
CONCLUSIONS: We report the highest frequency (92%) of BRAF V600E mutation in ameloblastomas in the Iranian population. Although there was not a significant association between BRAF V600E‑positive immunoexpression and recurrence and clinicopathologic parameters, its high frequency could emphasize its role as a therapeutic marker in the future. PMID: 32388526 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Influence of surgical ultrasound used in the detachment of flaps, osteotomy and odontosection in lower third molar surgeries. A prospective, randomized, and "split-mouth" clinical study.
CONCLUSIONS: Piezosurgery for tissue elevation of the surgical flap, osteotomy and dental sectioning in mandibular third molar extraction surgery promoted less edema in the early postoperative stages in mandibular third molar extractions despite the longer surgical duration. PMID: 32388527 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

What is the preferred concentration of ethanolamine oleate for sclerotherapy of oral vascular anomalies?
This study compared three different concentrations of EO (1.25%, 2.5% and 5%) for the treatment of oral vascular anomalies (OVAs). MATERIAL AND METHODS: This was a retrospective comparative analysis of patients with OVAs treated with EO. Anomalies smaller than 20 mm were included. The patients were treated with 1.25% (G1), 2.5% (G2), and 5% (G3) and clinical data were obtained. The number of sessions, the final volume and dose of EO were statistically analyzed to verify effectiveness and safety of the treatment. The different concentrations of EO were compared considering the number of sessions, the final volume and to...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

People would rather see a physician than a dentist when experiencing a long-standing oral ulceration. A population-based study in Spain.
CONCLUSIONS: General Galician population would seek professional consultation about a long-standing oral ulceration, relying mostly on primary care physicians. Those neglecting these lesions are elderly, less-schooled people and unaware of oral cancer. PMID: 32388529 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - May 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Marginal bone loss in the second molar related to impacted mandibular third molars: comparison between panoramic images and cone beam computed tomography.
This study aimed to assess and compare second molar bone loss adjacent to impacted mandibular third molar in panoramic radiographs (PAN) and cone beam computed tomography (CBCT) scans. MATERIAL AND METHODS: A sample of 70 patients was selected (n=124 teeth). Each patient had a set of a panoramic radiograph and CBCT scans consecutively taken for dental treatment purposes. In PAN and CBCT, mandibular third molars were classified based on their position and bone loss of the adjacent second molar. Agreement between PAN and CBCT scans was assessed and quantified. RESULTS: Outcomes of bone loss assessment were different ...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - April 10, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Clinical-pathological and sociodemographic factors associated with the distant metastasis and overall survival of oral cavity and oropharynx squamous cell carcinoma.
The objective of this study was to evaluate the influence of clinical-pathological and sociodemographic factors on the prevalence of distant metastasis (DM) and overall survival in patients with oral cavity and oropharynx squamous cell carcinoma (OOSCC). MATERIAL AND METHODS: Cross-sectional study based on the records of 404 OOSCC patients evaluated for DM, covering the period 2000-2014. We analysed the influence of age, sex, level of schooling, primary tumor subsite, treatment, marital status, family history of cancer, history of smoking and alcohol consumption, type of health care coverage (private vs. public) and ov...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - April 10, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Medication-related osteonecrosis of the jaws (MRONJ) in cancer patients treated with denosumab VS. zoledronic acid: A systematic review and meta-analysis.
CONCLUSIONS: Denosumab is associated with a significantly higher risk of developing MRONJ compared to ZA. Nevertheless, no differences were found in its prognoses. PMID: 32271321 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - April 10, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Assessing osseointegration of metallic implants with boronized surface treatment.
This study investigated the effect of implant surface boronization on bone healing. MATERIAL AND METHODS: Two implant surface roughness profiles (acid etched, machined) in CP titanium (type II) alloy implants were boronized by solid-state diffusion until 10-15µm boron coating was achieved. The surface-treated implants were placed bilaterally into 5 adult sheep ilia for three and six weeks. Four implant groups were tested: boronized machined (BM), boronized acid-etched (BAA), control machined (CM), and control acid-etched (CAA). Osseointegration was quantified by calculating bone to implant contact (BIC) and bone ...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - April 10, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Investigation of PTEN promoter methylation in ameloblastoma.
CONCLUSIONS: PTEN promoter methylation is found in a number of ameloblastomas but not significantly correlated with loss of PTEN expression. Genetic or epigenetic mechanisms other than PTEN promoter methylation may contribute to PTEN inactivation in ameloblastoma tumor cells. PMID: 32134893 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Does clinical findings correlate with magnetic resonance imaging (MRI) findings in patients with temporomandibular joint (TMJ) pain? A cross sectional study.
Authors: Koca CG, Gümrükçü Z, Bilgir E Abstract BACKGROUND: Although magnetic resonance imaging (MRI) helps to clearly visualize the disorders in temporomandibular joint (TMJ), the relationship between cross-sectional and clinical findings has not been precisely established. The aim of this study was to evaluate the relationship between clinical symptoms and MRI findings in individuals with TMJ pain. MATERIAL AND METHODS: This cross-sectional study, conducted on the clinical and MRI findings of the patients, who applied to Uşak University, Oral and Maxillofacial Surgery Clinic with TMJ pa...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Dermoid and epidermoid cysts of the oral cavity: a 48-year retrospective study with focus on clinical and morphological features and review of main topics.
CONCLUSION: Our results suggest that stratified squamous epithelium is the predominant epithelial lining of these cystic lesions. Also, we may find some unusual findings in DCs, such as Pacini bodies. PMID: 32134895 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Alveolar bone loss, platelet and glycosylated haemoglobin levels in 239 patients. A clinical study.
Authors: Pérez-Sayáns M, Blanco-Carrión A, García-García A, Chamorro-Petronacci CM, Ortega KL, Suárez-Quintanilla J Abstract BACKGROUND: The relation between periodontal disease and systemic pathologies is still not widespread among general practitioners. The aim of our study is to evaluate whether or not periodontal radiological diagnosis can aid the detection of blood alterations associated with acquired systemic diseases. MATERIAL AND METHODS: This is a cross sectional study. All of the participants underwent a panoramic radiograph and a complete blood test. Morpholo...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Mandibular incisive canal-related prevalence, morphometric parameters, and implant placement implications: a multicenter study of 847 CBCT scans.
This study evaluated the epidemiological and morphological features of the mandibular incisive canal (MIC) using cone beam computed tomography (CBCT) in a significant sample of subjects in Brazil. MATERIAL AND METHODS: This retrospective, multicenter study assessed 847 CBCT scans performed at four oral imaging centers. The sample comprised CBCT images acquired from dentate individuals who presented at least from tooth 35 to tooth 45 in the anterior mandible region. Data regarding patient sex and age, and MIC linear measurements (length and diameter in mm), anatomical distances (to the alveolar, buccal and lingual corte...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Prevalence of Apical Periodontitis in patients with Multiple Myeloma.
CONCLUSIONS: The presence of AP and endodontic treatment was not significantly different in individuals with MM compared with control subjects. Future studies are needed to elucidate and confirm the association between MM and AP. PMID: 32134898 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Oral Human Papillomavirus: a multisite infection.
CONCLUSIONS: HPV is frequently present in oral cavity as a multifocal infection, even without the presence of clinical lesions. PMID: 32134899 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Head and neck squamous cell carcinoma in young patients: a 26-year clinicopathologic retrospective study in a Brazilian specialized center.
CONCLUSIONS: HNSCC in young patients had a different profile when compared to older patients, especially regarding sex and exposure to the classic risk factors for this disease. The survival of the young group is similar to the older groups and advanced clinical stage is predictor of worse survival. PMID: 32134900 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Different methods of cell quantification can lead to different results: a comparison of digital methods using a pilot study of dendritic cells in HIV-positive patients.
Authors: Fernandes DT, van Heerden WF, Ribeiro AC, Brandão TB, Mello ES, Rivera C, van Heerden MB, Gondak R, Santos-Silva AR, Vargas PA, Lopes MA Abstract BACKGROUND: Although new digital pathology tools have improved the positive cell quantification, there is a heterogeneity of the quantification methods in the literature. The aim of this study was to evaluate and propose a novel dendritic cells quantification method in squamous cell carcinoma comparing it with a conventional quantification method. MATERIAL AND METHODS: Twenty-six squamous cell carcinomas HIV-positive cases affecting the oropharynx, lip...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Role of interleukin-4 in pathogenesis of oral lichen planus: A systematic review.
CONCLUSIONS: This review study shows that IL-4 plays a key role in the development of OLP. According to the past studies, there are several factors contributing to the production of this cytokine. Identification of the routes of production of IL-4 and its role in OLP might be useful for development of new preventive and therapeutic methods in management of patients with OLP. PMID: 32134902 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

One-year implant survival following lateral window sinus augmentation using plasma rich in growth factors (PRGF): a retrospective study.
CONCLUSIONS: Within the limitations of this study, dental implants placed in maxillary sinuses grafted with PRGF in combination with bone grafting materials, exhibit high implant survival rates after at least one year follow up. PMID: 32142503 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - March 7, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Patient morbidity after impacted third molar extraction with different flap designs. A systematic review and meta-analysis.
CONCLUSIONS: Despite its limitations, the present meta-analysis found no clear differences in patient morbidity between the different flap designs. PMID: 32062667 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 19, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Primordial odontogenic tumor: A systematic review.
Authors: Bologna-Molina R, Pereira-Prado V, Sánchez-Romero C, González-González R, Mosqueda-Taylor A Abstract BACKGROUND: The primordial odontogenic tumor (POT) is a recently described benign entity with histopathological and immunohistochemical features suggesting its origin during early odontogenesis. AIM: To integrate the available data published on POT into a comprehensive analysis to better define its clinicopathological and molecular features. MATERIAL AND METHODS: An electronic systematic review was performed up to September 2019 in multiple databases. RESULTS: A total of 13 ...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Trends of mortality due to oral and oropharyngeal cancers in Uruguay from 1997 to 2014.
CONCLUSIONS: The overall mortality from oral and oropharyngeal cancer in Uruguay has remained constant in the period between 1997 and 2014. Oral cancer mortality decreased in men and increased in women and decreased at the base of the tongue. It's necessary to continue monitoring the behavior of these diseases. PMID: 32040460 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Estimation of the age of majority through radiographic evaluation of the third molar maturation degree.
CONCLUSIONS: Our results showed that subjects with the lower third molars in the highest maturational stage could be estimated to be older than 18 years and therefore considered of legal age, a finding also reported by other authorsThe Demirjian´s tooth maturational stage method, applied to the lower third molars, can be reliably used to estimate whether an individual is of legal age (18 years or older). High concordance between different observers using this method can be expected. PMID: 32040461 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Hyaluronic acid treatment outcome on the post-extraction wound healing in patients with poorly controlled type 2 diabetes: A randomized controlled split-mouth study.
Authors: Marin S, Popovic-Pejicic S, Radosevic-Caric B, Trtić N, Tatic Z, Selakovic S Abstract BACKGROUND: Hyaluronic acid is widely used in the medical field. However, there is a lack of research about its effect on patients with certain risks, such as compromised wound healing commonly found in patients with poorly controlled type 2 diabetes. The aim of this study is to investigate the efficacy of hyaluronic acid on the post-extraction wound healing and pain in patients with poorly controlled type 2 diabetes. MATERIAL AND METHODS: The randomized controlled split-mouth study was designed, which included 30 pa...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

A retrospective 11-year study on lip lesions attended at an oral diagnostic service.
The objective of this study was to describe the upper and lower lip lesion occurrence in an oral diagnostic service. MATERIAL AND METHODS: Retrospective descriptive sectional study was performed. Clinical records were obtained from the archives of an Oral Diagnostic Service referral center between 2006 and 2016. Data such as gender, age, anatomical location, and diagnosis were collected and categorized. The collected data were submitted to a descriptive analysis and Pearson's chi-square test (p ≤ 0.05). RESULTS: A total of 587 patient records of lip lesions were analyzed. Most lesions were diagnosed in female (5...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Quality of information about oral cancer in Brazilian Portuguese available on Google, Youtube, and Instagram.
CONCLUSIONS: Information on oral cancer on the Internet in Brazilian Portuguese is of low quality. Thus, educational and governmental institutions have a responsibility to produce and indicate reliable sources of information for the population. PMID: 32040464 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Short implants ( < 8mm) versus longer implants ( ≥8mm) with lateral sinus floor augmentation in posterior atrophic maxilla: A meta-analysis of RCT`s in humans.
Short implants (
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Tooth avulsion accidents due to urgent and emergency orotracheal intubation.
CONCLUSION: Pulmonary problems were the major causes of intubation, with the highest tooth avulsion prevalence observed during emergency intubation. The avulsed teeth were 11, 12, 13, 22, 32, and 33 across all cases. PMID: 32040466 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Metagenomic investigation of bacteria associated with dental lesions: a cross-sectional study.
CONCLUSIONS: Exploring the dental microbiota and comparing them in health or diseased conditions is critical step in the determination of human general health. The method applied in this study could identify bacteria related to the three dental lesions. However, due to lack of data for comparison in Genbank or because of the sequence similarity lower than 98% for most identified bacteria, the use of more powerful approaches like NGS platforms or typing of multiple loci (MLST) in future studies is recommended. PMID: 32040467 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Assessment of clinical outcomes and histomorphometric findings in alveolar ridge augmentation procedures with allogeneic bone block grafts: A systematic review and meta-analysis.
CONCLUSIONS: Atrophic alveolar crest reconstruction with allogeneic bone block grafts would appear a feasible alternative to autologous bone block grafts, obtaining a low block graft failure rate, similar implant survival rate and fewer postoperative complications. Further investigations generating long term data are needed to confirm these findings. PMID: 32040468 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Salivary biomarkers for diagnosis of systemic diseases and malignant tumors. A systematic review.
CONCLUSIONS: The present systematic review confirms the existence of some "good" quality evidence to support the role of peculiar salivary biomarkers for diagnosis of systemic diseases (e.g. lung cancer and EGFR). PMID: 32040469 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Influence of information concerning a computerized anesthesia system on dental anxiety: a randomized controlled clinical trial.
CONCLUSIONS: Patients that received a detailed explanation of The Wand did not have a significant reduction of the anxiety degree and perceived pain during the anesthetic act compared to patients that received no information. The need of re-anesthesia was not related to the anxiety level but was significantly related to increasing operative time. PMID: 32040470 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - February 12, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Immunohistochemical analysis of cancer-associated fibroblasts and podoplanin in head and neck cancer.
CONCLUSIONS: The presence of CAFs in the tumour stroma is related to an aggressive phenotype and could increase as the disease progresses, although based on our findings, it would have no relationship, at least directly, with the expression of PDPN. PMID: 31967978 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - January 24, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Evaluation of effectiveness of photobiostimulation in alleviating side effects after dental implant surgery. A randomized clinical trial.
Authors: Caccianiga G, Perillo L, Portelli M, Baldoni M, Galletti C, Gay-Escoda C Abstract BACKGROUND: To assess if photobiostimulation (PBS) alleviates pain intensity/duration and swelling after implant surgery. MATERIAL AND METHODS: Sixty subjects (27 male and 33 female, with a mean age of 47,13 8.05 years) were included and randomly assigned to experimental group (implant surgery and photobiostimulation), placebo group (implant surgery and simulated photobiostimulation) and control group (implant surgery only). INCLUSION CRITERIA: subjects older than 20 years, with a healthy oral mucosa and requiring imp...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - January 24, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Comparison of diode laser - Oral tissue interaction to different wavelengths. In vitro study of porcine periodontal pockets and oral mucosa.
CONCLUSIONS: According to our results, the 810nm diode laser for oral soft-tissue biopsy using power ranges between 0.5W and 2W would be the best choice to avoid thermal damage in peri-incisional margins. PMID: 31967980 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - January 24, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

SOX2 and BCL-2 Expressions in Odontogenic Keratocyst and Ameloblastoma.
Authors: Silva BS, Silva LR, Lima KL, Dos Santos AC, Oliveira AC, Dezzen-Gomide AC, Batista AC, Yamamoto-Silva FP Abstract BACKGROUND: The purpose of this experimental study was to compare the immunohistochemical expression of SOX2 and BCL-2 in Odontogenic Keratocyst (OKC) and Ameloblastoma (AB) specimens, and to identify a possible correlation in their expression. MATERIAL AND METHODS: Immunohistochemical analysis was performed to evaluate SOX2 and BCL-2 expression in OKC (n = 20) and AB (n = 20). The immunoexpression was analyzed by a quantitative and qualitative scoring system. The comparison between the imm...
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - January 24, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

Prognostic value of the immunohistochemical detection of epithelial-mesenchymal transition biomarkers in oral epithelial dysplasia: A systematic review.
CONCLUSIONS: The dysregulation of expression of important EMT components in oral dysplastic epithelium is a potential prognostic marker in OPMDs. PMID: 31967982 [PubMed - as supplied by publisher] (Source: Medicina Oral, Patologia Oral y Cirugia Bucal)
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - January 24, 2020 Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research