Effects of a gluten-reduced or gluten-free diet for the primary prevention of cardiovascular disease

CONCLUSIONS: Very low-certainty evidence suggested that it is unclear whether gluten intake is associated with all-cause mortality. Our findings also indicate that low-certainty evidence may show little or no association between gluten intake and cardiovascular mortality and non-fatal myocardial infarction. Low-certainty evidence suggested that a lower compared with a higher gluten intake may be associated with a slightly increased risk to develop type 2 diabetes - a major cardiovascular risk factor. For other cardiovascular risk factors it is unclear whether there is a difference between a gluten-free and normal diet. Given the limited findings from this review predominantly based on observational studies, no recommendations for practice can be made.PMID:35199850 | DOI:10.1002/14651858.CD013556.pub2

Source: Cochrane Database of Systematic Reviews - February 24, 2022 Category: General Medicine Authors: Christine Schmucker Angelika Eisele-Metzger Joerg J Meerpohl Cornelius Lehane Daniela Kuellenberg de Gaudry Szimonetta Lohner Lukas Schwingshackl Source Type: research