Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review.

Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review. Nutr Cancer. 2020 Jul 10;:1-12 Authors: Barati M, Jabbari M, Nickho H, Esparvarinha M, Javadi Mamaghani A, Majdi H, Fathollahi A, Davoodi SH Abstract This systematic review assesses the literature regarding beneficial and potential detrimental effects of bioactive peptides (BPs), focusing on evidence of regulatory T cells (T-regs) mediated oral tolerance (OT), collagen hydrolysate (CH) supplementation in osteoarthritis (OA) and the association of T-regs with chronic disease. The systematic search was done for articles published from inception to April 2019 using the PubMed and Scopus databases. About 3081 papers were identified by three different search strategies and screened against inclusion criteria which resulted in the inclusion of 22 articles. From the included articles, 12 papers were related to treatment of different disease in vivo by oral administration of BPs, six articles evaluated the effects of CH supplementation, as a rich source of BPs, on OA pain-relief and four observational studies assessed the association of circulating T-regs and risk of cancer and cardiovascular disease (CVD). The evidence obtained from first search strategy, indicated that oral administration of BPs improve clinical manifestations of animal models of allergy, arthritis, atherosclerosis, ulcerative colitis and allogra...
Source: Nutrition and Cancer - Category: Cancer & Oncology Authors: Tags: Nutr Cancer Source Type: research

Related Links:

Publication date: Available online 2 August 2020Source: Cirugía Española (English Edition)Author(s): Sheila Serra-Pla, Anna Pallisera-Lloveras, Laura Mora-López, Ana Granados Maturano, Sebastian Gallardo, Carmen del Pino Zurita, Xavier Serra-Aracil
Source: Cirugia Espanola - Category: Surgery Source Type: research
Former PA Training Instructor Elected to U.S. House of Representatives | Inside PA Training Congresswoman Karen Bass As strident as midterm election politics were this year, and whatever your political stripe, you'll probably be pleased to hear that the US House of Representatives will have its first PA in office when the 122nd Congress convenes this January. With www.mypatraining.com
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Solar ultraviolet radiation (UVR) induces the production of vitamin D (VD), but it also causes erythema and skin cancer among other diseases. The amount of UVR to get benefit and avoid harm is unknown. Some principles were proposed to provide accessible information on how to avoid overexposure to the Sun. They are (1) the Shadow Rule (SR); (2) the UV Index (UVI); and (3) the Slip, Slop, Slap, Seek, Slide (5S) steps. This work discusses these principles in the tropics, considering measurements of solar UVR, total ozone column, and cloudiness. Indeed, the SR leads to overexposures. The UVI is adequate for cloudless skies, bu...
Source: Health Physics - Category: Radiology Tags: NOTES Source Type: research
The excess relative risk (ERR) of mortality for circulatory disease among nuclear workers was reanalyzed by taking into consideration the annual dose as the dose rate using publicly available epidemiological data of the Hanford site dedicated to the cohort study of nuclear workers in the US, the UK, and Canada. Values of the dose rate (cut-points) were chosen at 2 mSv y−1 intervals from 2 to 40 mSv y−1, and risk estimates were made for 32,988 workers, considering the doses accumulated below and above each cut-point to have different effects. Similarly to that in the previous study for cancer by Sasaki et al., e...
Source: Health Physics - Category: Radiology Tags: PAPERS Source Type: research
The Radiation and Nuclear Countermeasures Program at the National Institute of Allergy and Infectious Diseases (NIAID) mandated that medical countermeasures for treating Acute Radiation Syndrome (ARS) must have efficacy when administered at least 24 h after radiation exposure. At this time point, many cells within key target tissues, such as the hematopoietic system and the gastrointestinal (GI) tract, will already be dead. Therefore, drugs that promote the regeneration of surviving cells may improve outcomes. The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) regulates stem and progenitor cell self-renewal and...
Source: Health Physics - Category: Radiology Tags: PAPERS Source Type: research
Conclusions: For the studied children, the use of traditional BMI references may result in the overestimation of underweight and underestimation of overweight and obesity. Studies should be carried out with periodic updates, respecting the characteristics of each location in order to use BMI reference values to classify the nutritional status of children and adolescents.RESUMO Objetivo: Determinar novos valores de refer ência do índice de massa corporal (IMC) para a classificação do estado nutricional de crianças de seis a 10 anos da cidade de Montes Claros (MG) Brasil. Métodos: Foi...
Source: Revista Paulista de Pediatria - Category: Pediatrics Source Type: research
Conclusions: Patients with hematologic tumors had an increase in body weight, height, and fat mass, which was not identified in the solid tumor group. The positive correlation between anthropometry (triceps skinfold thickness and arm muscle circumference), deuterium oxide dilution, and bioelectric impedance analysis shows the applicability of anthropometry in clinical practice.RESUMO Objetivo: Verificar mudan ças no estado nutricional de crianças com câncer antes e após o tratamento quimioterápico e avaliar a correlação entre diluição de óxido de deut&eac...
Source: Revista Paulista de Pediatria - Category: Pediatrics Source Type: research
In conclusion, both elastic stable intramedullary nailing and external fixation can achieve satisfactory clinical and radiographic outcomes in children with acute Monteggia fractures. However, the rate of residual pain and less satisfactory clinical appearance was higher in patients managed by external fixation compared to those treated by elastic stable intramedullary nailing. According to our results, elastic stable intramedullary nailing should be used as primary treatment option in children with acute Monteggia fracture requiring surgical management.
Source: Journal of Pediatric Orthopaedics B - Category: Orthopaedics Tags: Pediatric Orthopedic Surgery in China Special Issue Source Type: research
The aim of this study was to explore the clinical features and surgical treatment methods of unstable midfoot injuries in children. Eleven children with severe unstable midfoot injuries admitted to Jishuitan Hospital, Beijing, from June 2009 to October 2016 were enrolled, including seven patients with Lisfranc injuries and four patients with Chopart injuries. All Lisfranc injuries had radiographic data from the healthy sides, and radiographs of the affected sides showed that all injured Lisfranc joints separated more than 3 mm compared with the healthy sides. The treatment methods employed a joint-spanning external fixator...
Source: Journal of Pediatric Orthopaedics B - Category: Orthopaedics Tags: Pediatric Orthopedic Surgery in China Special Issue Source Type: research
We describe the surgical technique and, using an illustrative case, compare the outcome of this technique with the outcome following reconstruction without reinforcement. Level of evidence: Level III.
Source: Journal of Pediatric Orthopaedics B - Category: Orthopaedics Tags: Bone Tumours Source Type: research
More News: Allergy | Allergy & Immunology | Arthritis | Bone Graft | Cancer | Cancer & Oncology | Cardiology | Cardiovascular | Chronic Pain | Databases & Libraries | Heart | Inflammatory Bowel Disease | Nutrition | Oral Cancer | Osteoarthritis | Pain | Rheumatology | Study | Ulcerative Colitis