What Causes Bradycardia?
Discussion Bradycardia is a heart rate below what the lowest value that is normal for age. Infants and children have higher heart rates that slowly decrease with age to adult levels. It is usually noted as an incidental finding because of increased vagal tone. Reasons for cardiology referral include associated heart murmur, syncope especially if associated with exercise or unusual triggers, other signs such as chest pain or palpitations, family history of sudden cardiac death, congenital heart disease or familial heart disease, bradycardic medication use, or unusual symptoms associated with the concern. Severe bradycardia that causes poor cardiac output is a medical emergency. Fortunately most children have mild bradycardia which may have no symptoms or can manifest as dizziness, syncope, exercise intolerance or fatigue. Evaluation includes a good history and physical examination. Electrocardiogram may determine a rhythm abnormality but often an ambulatory Holter monitoring will be needed as the bradycardia and/or rhythm may be intermittent. Echocardiogram may be appropriate if congenital heart disease is suspected. Exercise stress testing is usually not need but can determine if the heart is appropriately responsive during exercise. Learning Point The differential diagnosis of bradycardia includes: Athletes, well trained Hypervagotonia this is a sinus bradycardia Apnea and bradycardia in infants Breathholding spells Coughing Emesis Gastroesophageal reflux Increased...
Publication date: Available online 30 September 2020Source: Journal of Hazardous MaterialsAuthor(s): Anthony Beauvois, Delphine Vantelon, Jacques Jestin, Martine Bouhnik-Le Coz, Charlotte Catrouillet, Valérie Briois, Thomas Bizien, Mélanie Davranche
We describe the most highly recommended generic and disease-specific PRO tools in SCD and discuss the challenges of incorporating them in clinical practice. EXPERT OPINION: PRO measures are essential to incorporate into SCD clinical trials either as primary or secondary outcomes. The use of PRO measures in SCD facilitates a patient-centered approach, which is likely to lead to improved outcomes. Significant challenges remain in adapting PRO tools to routine clinical use and in developing countries. PMID: 33034214 [PubMed - as supplied by publisher]
Currently in fellowship doing bread/butter procedures (MBB, epidurals, PNB, few SCS/PNS trials, etc.) and just interviewed at a private practice spot where they do a lot of procedures that I will have not done any training in prior to graduating (e.g. IT pump, SI fusion, Vertiflex, Kypho, MILD, Discectomy, lots of SCS/PNS trials etc) and significant amount of "OR pain procedures" at a very busy practice seeing 30-40 pts/day - how many of you are commonly performing these procedures and are... private practice concern
Authors: Saavedra J, Reyes JG, Salinas DG Abstract Cytosolic Ca2+ concentration ([Ca2+ ]) has an important role in spermatozoa and hence it regulates fertilization. In male germinal cells, there are indirect evidences that this ion could regulate physiological processes in spermatogenesis. Since little is known about Ca 2+ homeostasis in spermatogenic cells, in this work we propose a mathematical model that accounts for experimental [Ca2+ ] dynamics triggered by blockade of the SERCA transport ATPase with thapsigargin in round rat spermatids, without external Ca2+ and with different extracellular lactate concentrat...
Abstract Lithium (Li+) is used in various applications involving pharmaceuticals, textile dyes, and batteries. Therefore, the demand for environmentally friendly and effective materials for Li+ uptake and recovery continues to increase. Herein, rice husk (RH) and coconut shell (CS) biomasses were used to fabricate honeycomb-networked biochar (BC) precursors via slow pyrolysis. RHBC- and CSBC-based MnO2 composites were synthesized by depositing MnO2 in various ratios onto RHBC and CSBC by varying the KMnO4 concentration (2%, 3%, and 4%), followed by simple ultrasonication and heat-treatment methodologies. The struc...
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Publication date: October 2020Source: Brain, Behavior, and Immunity, Volume 89Author(s): Fernando Lopes, Fernando A. Vicentini, Nina L. Cluny, Alexander J. Mathews, Benjamin H. Lee, Wagdi A. Almishri, Lateece Griffin, William Gonçalves, Vanessa Pinho, Derek M. McKay, Simon A. Hirota, Mark G. Swain, Quentin J. Pittman, Keith A. Sharkey
BEST supplements to relieve joint pain: Is your arthritis playing up? The wetter and colder months could partially be to blame. These two pills may help.
Authors: Kim H, Lim YM, Lee EJ, Kim HW, Ahn HS, Kim KK PMID: 33029979 [PubMed]
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