Climate Change Is Making Us Sick, Says WHO Envoy
The World Health Organization says round 7 million people die prematurely each year due to air pollution. Credit: Busani Bafana/IPSBy Busani BafanaBULAWAYO, Aug 2 2023 (IPS) Climate change is making us sick. It has become urgent to build resilient health systems to secure humanity’s well-being, says the special envoy for climate change and health of the World Health Organization (WHO). “Climate change is unquestionably affecting our health every day,” says Vanessa Kerry– a renowned global health expert and medical doctor – who was appointed the WHO Director-General’s Special Envoy for Climate Change and Health ...
Source: IPS Inter Press Service - Health - August 2, 2023 Category: International Medicine & Public Health Authors: Busani Bafana Tags: Climate Action Climate Change Editors' Choice Featured Global Headlines Health TerraViva United Nations IPS UN Bureau IPS UN Bureau Report Source Type: news

Patients Can Die: Screen Organ Donors for This Parasitic Disease Patients Can Die: Screen Organ Donors for This Parasitic Disease
Bob Naedele died after receiving a heart from a donor with Chagas disease. His death could have been prevented had the donor been tested.ProPublica (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 23, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Integrating Chagas disease screening into primary health care
Yale experts discuss access to screening and treatment for the epidemic that has spread over a century from rural areas of Latin America to the United States. (Source: Yale Science and Health News)
Source: Yale Science and Health News - April 13, 2023 Category: Universities & Medical Training Source Type: news

Parasite Drove Natural Selection in Amazonian Indigenous Groups
The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease. (Source: The Scientist)
Source: The Scientist - March 13, 2023 Category: Science Tags: News & Opinion Source Type: news

Indigenous groups in the Amazon evolved resistance to deadly Chagas
Humans have evolved to have some remarkable superpowers. People can thrive at high altitudes, dive for long periods underwater, and even tolerate a glass of lactose-rich milk well into adulthood. Now, a new study of Indigenous peoples from the Amazon rainforest reveals one more such adaptation: a genetic resistance to the endemic parasite responsible for deadly Chagas disease. The study’s findings could help scientists develop desperately needed new therapies for the disease, which infects roughly 6 million people in Latin America and is a leading cause of death in the region. “This paper is very important,” sa...
Source: ScienceNOW - March 8, 2023 Category: Science Source Type: news

Kissing Bug Confidential: Priorities for Managing Chagas Disease
(MedPage Today) -- Kissing bug. Cone-nosed bug. Vinchuca. Chipo. Barbeiro. These English, Spanish, and Portuguese names are local sobriquets for nocturnal, blood-sucking insects that transmit a zoonotic parasite native to Latin America. In recent... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 8, 2023 Category: Infectious Diseases Source Type: news

Possible new treatment identified for neglected tropical disease
The last time a new drug for Chagas disease was introduced, Richard Nixon was in his first term as U.S. president. Now, in a study published yesterday, researchers unveil a drug that appears to safely eliminate from mice and monkeys the parasites that cause the sometimes-fatal tropical disease. The scientists hope clinical trials of the compound can begin soon and that it will have fewer side effects than the current Chagas treatments. The study is “very impressive” and provides enough evidence to support human testing, says medical epidemiologist Caryn Bern of the University of California, San Francisco, who was...
Source: ScienceNOW - September 6, 2022 Category: Science Source Type: news

Characteristics and Adverse Events of Patients for Whom Nifurtimox Was Released Through CDC-Sponsored Investigational New Drug Program for Treatment of Chagas Disease - United States, 2001-2021
This report describes the treatment of Chagas disease using nifurtimox. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 10, 2022 Category: American Health Tags: Chagas Disease (Trypanosoma cruzi Infection) MMWR Morbidity & Mortality Weekly Report Drug Therapy Source Type: news

Janssen Announces Novel Mechanism of Action that Shows Promise Against Dengue in Data Published in Nature
BEERSE, BELGIUM, October 6, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) announced today, in collaboration with the KU Leuven Rega Institute and the KU Leuven Centre for Drug Design and Discovery (CD3), the publication of new preclinical data in the journal Nature showing that an early-stage compound with a novel mechanism of action could potentially treat all serotypes of dengue fever and provide a period of protection against acquiring the dengue virus. Janssen is now moving its dengue program into clinical development. Data from the early-stage study suggest that an antiviral compound...
Source: Johnson and Johnson - October 6, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

The Diagnosis We're All Missing, and Why That Must Change The Diagnosis We're All Missing, and Why That Must Change
It ' s not just a disease of Latin America; there are an estimated 300,000 cases of Chagas disease in the United States. Are you prepared to make the diagnosis?Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - April 14, 2021 Category: Infectious Diseases Tags: Infectious Diseases Commentary Source Type: news

Enhanced scorpion venom molecules can be used to treat Chagas disease
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Brazilian researchers tested the antichagasic properties of VmCT1, obtained from the venom of Vaejovis mexicanus, a scorpion harmless to humans, and synthesized novel analogs to redesign the native molecule (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 21, 2020 Category: Biology Source Type: news

Parasitology - Bringing the locals onboard
(Ludwig-Maximilians-Universit ä t M ü nchen) A new study examines local perceptions of Chagas disease in a region where the infectious agent is endemic. The results underline the need to take social and cultural factors into account in campaigns designed to curb infectious diseases. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 30, 2020 Category: Infectious Diseases Source Type: news

Stronger treatments could cure Chagas disease
(University of Georgia) Researchers in the University of Georgia's Center for Tropical and Emerging Global Diseases have found that a more intensive, less frequent drug regimen with currently available therapeutics could cure the infection that causes Chagas disease (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 29, 2020 Category: International Medicine & Public Health Source Type: news

Study finds asymptomatic Chagas patients are at a high risk for cardiac disease
(University of Colorado Anschutz Medical Campus) People living with Chagas disease without symptoms or signs of cardiac injury are at high risk of developing cardiomyopathy, a progressive heart disease, and the risk more than doubled among patients with acute infections, according to a new study from the University of Colorado School of Medicine at the Anschutz Medical Campus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 31, 2020 Category: Infectious Diseases Source Type: news

FDA Approves Lampit (nifurtimox) for the Treatment of Chagas Disease in Children
WHIPPANY, N.J.--(BUSINESS WIRE) August 7, 2020 -- Bayer announced today that the United States Food and Drug Administration (FDA) has approved Lampit (nifurtimox) for use in pediatric patients (from birth to less than 18 years of age and weighing at... (Source: - New Drug Approvals)
Source: - New Drug Approvals - August 7, 2020 Category: Drugs & Pharmacology Source Type: news