Reality of clonidine poisoning in children and adolescents - Duong C, Lovett C, Downes MIA, Isbister GK.
AIM: We aimed to describe the severity of clonidine poisonings in a paediatric population referred to a tertiary toxicology service. METHODS: We undertook a retrospective review of all presentations of clonidine poisoning in children or adolescents... (Source: SafetyLit)
Source: SafetyLit - April 13, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Clonidine Suppression Test for a Pheochromocytoma Diagnosis Clonidine Suppression Test for a Pheochromocytoma Diagnosis
A new study evaluates the potential role of the clonidine suppression test in the assessment of suspected pheochromocytoma/paraganglioma.Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 10, 2022 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Non-opioid compounds squelch pain without sedation
A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco. The molecules act on the same receptor as clonidine and dexmedetomidine - drugs commonly used in hospitals as sedatives - but are chemically unrelated to them and may not be addictive. (Source: World Pharma News)
Source: World Pharma News - September 30, 2022 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
Notes from the field: xylazine, a veterinary tranquilizer, identified as an emerging novel substance in drug overdose deaths -- Connecticut, 2019-2020 - Thangada S, Clinton HA, Ali S, Nunez J, Gill JR, Lawler RF, Logan SB.
Xylazine, a clonidine analog, is a nonopioid veterinary tranquilizer not intended for human use. Recreational drugs such as cocaine, heroin, and fentanyl are often adulterated with agents such as xylazine to enhance drug effects or increase street value by... (Source: SafetyLit)
Source: SafetyLit - September 18, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
What Causes Anisocoria?
Discussion Anisocoria is a common physical finding caused by the mechanical imbalance of the iris dilator (sympathetic innervation causing dilation) and sphincter muscles (parasympathetic innervation causes miosis). Which pupil is abnormal is important to determine. “Anisocoria greater in the light signifies an abnormal large pupil, whereas anisocoria in the dark indicates an abnormal small pupil.” The pupillary size should be noted along with any changes with accommodation, extra ocular movements and lighting. The time it takes to revert to the baseline pupillary size can also be helpful. Any ptosis, lacrimati...
Source: PediatricEducation.org - August 23, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Class 3 Medicines Recall: SyriMed, Clonidine hydrochloride 50micrograms/5ml Oral Solution
SyriMed are recalling the batches of Clonidine hydrochloride 50micrograms/5ml Oral Solution as a precautionary measure due to an issue related to the container closure (child-lock cap). Further detai (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 17, 2021 Category: Drugs & Pharmacology Source Type: news
"Road rash" and dizziness: a case of hemodynamically significant topical clonidine toxicity - Downs JW, Cumpston KL.
We report a case of uninten... (Source: SafetyLit)
Source: SafetyLit - October 5, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
What Causes Bradycardia?
Discussion Bradycardia is a heart rate below what the lowest value that is normal for age. Infants and children have higher heart rates that slowly decrease with age to adult levels. It is usually noted as an incidental finding because of increased vagal tone. Reasons for cardiology referral include associated heart murmur, syncope especially if associated with exercise or unusual triggers, other signs such as chest pain or palpitations, family history of sudden cardiac death, congenital heart disease or familial heart disease, bradycardic medication use, or unusual symptoms associated with the concern. Severe bradycardia ...
Source: PediatricEducation.org - June 22, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Fresenius Kabi's Recall of Ketorolac Results In QuVa Pharma ® Recall of Compounded Sterile Product (R.E.C.K.)
QuVa Pharma, Inc. confirms that is working with the U.S. Food and Drug Administration, and voluntarily recalling all lots of R.E.C.K. (Ropivacaine, Epinephrine, Clonidine, Ketorolac) 50 ml in Sodium Chloride-60 ml BD syringe that were prepared using sterile Ketorolac being recalled by Fresenius Kabi (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 27, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news
What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Medicine Supply Notifications - Clonidine and H2-antagonists (cimetidine, famotidine and nizatidine)
The Department of Health and Social Care (DHSC) has issued the following Medicine Supply Notifications: (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - December 23, 2019 Category: Drugs & Pharmacology Source Type: news