Associations of antiretroviral therapy and comorbidities with neurocognitive outcomes in HIV-1-infected patients
Conclusion: ART may reduce the risk of NCIs in HIV-infected patients in general. Further research to investigate NCIs on specific antiretroviral regimens and comorbidities may provide insights regarding the long-term clinical care of these patients.
(American Association for Cancer Research) Among patients with both colorectal cancer and diabetes in Korea, those who had a high adherence to their oral diabetes medication had a significantly reduced risk of overall mortality compared with those with lower adherence.
Publication date: Available online 30 May 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Alpna Tyagi, Carol Mirita, Nadine Taher, Iman Shah, Emily Moeller, Anit Tyagi, Thomas Chong, Subbiah Pugazhenthi
Publication date: Available online 28 May 2020Source: NeuroImage: ClinicalAuthor(s): Anson C.M. Chau, Eva Cheung, K.H. Chan, W.S. Chow, Y.F. Shea, Patrick K.C. Chiu, Henry K.F. Mak
Publication date: Available online 26 May 2020Source: NeuroImage: ClinicalAuthor(s): Kl. West, Dk. Sivakolundu, Gb. Maruthy, Md. Zuppichini, P. Liu, Bp. Thomas, Js. Spence, H. Lu, Dt. Okuda, B. Rypma
Publication date: Available online 26 May 2020Source: NeuroImage: ClinicalAuthor(s): Sonsoles Alonso Martínez, Jan-Bernard C. Marsman, Morten L. Kringelbach, Gustavo Deco, Gert J. ter Horst
Publication date: Available online 26 May 2020Source: NeuroImage: ClinicalAuthor(s): Chanon Ngamsombat, Qiyuan Tian, Qiuyun Fan, Andrew Russo, Natalya Machado, Maya Polackal, Ilena C. George, Thomas Witzel, Eric C. Klawiter, Susie Y. Huang
Publication date: Available online 26 May 2020Source: NeuroImage: ClinicalAuthor(s): Jae-Won Jang, Yeshin Kim, Seongheon Kim, Sang Won Park, Sung Ok Kwon, Young Ho Park, Jae-Sung Lim, Young Chul Youn, Sung Hun Kim, SangYun Kim, Alzheimer's Disease Neuroimaging Initiative
Publication date: Available online 30 May 2020Source: Social Science &MedicineAuthor(s): Jonathan M. Platt, Lisa Bates, Justin Jager, Katie A. McLaughlin, Katherine M. Keyes
This study aimed to investigate the effects of hirudin on the production of extracellular matrix (ECM) factors by renal tubular epithelial cells in a rat model of diabetic kidney disease (DKD) and HK-2 human renal tubule epithelial cells. MATERIAL AND METHODS Sprague-Dawley rats were divided into the normal control group (n=10), the normal control+hirudin group (n=10), the DKD model group (n=12) and the DKD+hirudin group (n=12). At the end of the study, renal histopathology was undertaken, and the expression of type IV collagen, fibronectin, hypoxia-inducible factor-1alpha (HIF-1alpha), and vascular endothelial growth fact...
ConclusionsThe grades of BPD-specific symptom severity derived from the distribution of the BSL-23 scores received consistent empirical validation from established assessments for psychopathology. Future studies should expand this validation by including additional instruments e.g., to assess self-esteem, loneliness, connectedness, and quality of life.
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