Virological and epidemiological patterns of swine influenza A virus infections in France: cumulative data from the RESAVIP surveillance network, 2011–2018

This study reports virological and epidemiological data accumulated through passive surveillance conducted during 1,825 herd visits from 2011 to 2018. Among them, 887 (48.6%) tested swIAV-positive. The proportion of positive cases remained stable year-on-year and year-round. The European avian-like swine H1N1 (H1avN1) virus was the most frequently identified (69.6%), and was widespread across the country. The European human-like reassortant swine H1N2 (H1huN2) virus accounted for 22.1% and was only identified in the north-western quarter and recently in the far north. The 2009 pandemic H1N1 (H1N1pdm) virus (3.6%) was detected throughout the country, without settling in areas of higher pig densities. Its proportion increased in winter, during the seasonal epidemics in humans. The European human-like reassortant swine H3N2 as well as H1avN2 viruses were identified sporadically. In up to 30% of swIAV-positive cases, pigs exhibited clinical signs of high intensity, regardless of the viral subtype and vaccination program. The recurrent pattern of the disease, i.e., an endemic infection at the herd level, was reported in 41% of cases and mainly affected post-weaning piglets (OR = 5.11 [3.36-7.76]). Interestingly, the study also revealed a significant association between the recurrent pattern and sow vaccination (OR = 1.96 [1.37-2.80]). Although restricted to the studied pig population, these results bring new knowledge about swIAV dynamics and infection ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research

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Source: SafetyLit - Category: International Medicine & Public Health Tags: Media, Marketing, and Internet Issues Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Commentary Source Type: news
Contributors : Catherine J Wu ; Derin B KeskinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPrediction of HLA epitopes is important for the development of cancer immunotherapies and vaccines. However, current prediction algorithms have limited predictive power, in part because they were not trained on high-quality epitope datasets covering a broad range of HLA alleles. To enable prediction of endogenous HLA class I-associated peptides across a large fraction of the human population, we used mass spectrometry to profile>185,000 peptides eluted from 95 HLA-A, -B, -C and -G mono-all...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
We report a case series of 5 patients with PMD and unsatisfactory refractive correction managed at Clermont-Ferrand university hospital from January to December 2018 fitted with customized SPOT scleral lenses. We assessed the best-corrected visual acuity (BCVA) before and after fitting with SPOT, keratometric data and tolerability of the scleral lenses. RESULTS: Nine eyes of 5 patients aged 51.8±8.47 years were fitted. The BCVA was significantly improved from 0.51 logMAR (±0.39) to 0.04 logMAR (±0.07) (P
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
This study aims to determine the knowledge, attitude, and behaviors of teachers regarding human papillomavirus (HPV) and its vaccination. This cross-sectional study included teachers from 30 schools of the Kahramanmara ş city between 01 March 2015 and 09 June 2015. The teachers were informed prior to the study, and 804 teachers giving written consents were enrolled. Nine questions (9 points) to ascertain the knowledge of teachers regarding HPV and 5 questions to detect the knowledge level about HPV vaccination we re prepared from the literature. Of the participants, 448 (55.7%) were men and 356 (44.3%) were women with a m...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
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Source: Molecular Phylogenetics and Evolution - Category: Molecular Biology Source Type: research
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Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
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Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
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