No proof coffee causes obesity and diabetes

Conclusion This rodent research suggests that mice given a high-fat diet supplemented with the polyphenol chlorogenic acid (CGA) fared worse than those given a high-fat diet. But this was only in terms of measures of glucose regulation that are related to the risk of developing type 2 diabetes. The researchers point out that other studies have found that giving CGA to mice improved measures of their glucose regulation. When there are contradictory results from different studies like this, it can indicate that the biological processes involved are not fully understood. Because of this, these results are not likely to be reliable on their own. A better consensus of what is going on may come through further research into the area. There are further limitations with this research to consider when thinking about the impact of this study: The equation of the amount of CGA given to the mice to five cups of coffee in humans was relatively crude and may not be accurate. However, the researchers did make an effort to give the mice a dose of CGA that they thought might be roughly equivalent to the amount a person could get through drinking coffee, although it wasn't clear what type or strength of coffee this would be. The researchers suggest that the results could have been influenced by the bacteria present in the guts of the mice. They suggest the gut bacteria can degrade CGA, which would alter its biological effect in the body. The precise combination of gut bacteria varie...
Source: NHS News Feed - Category: Consumer Health News Tags: Food/diet Diabetes Obesity Source Type: news