Molecule limits heart attack damage in mice
Conclusion This laboratory-based research in mice, which used a simulation designed to mimic the effects of a heart attack, appears to show that the molecule MitoSNO can prevent some of the heart tissue damage of a heart attack and the consequences of the return of blood to the heart (reperfusion). It is important to remember this was a small, early study in mice. Further studies in rodents would be needed to confirm these initial findings as true and accurate. Furthermore, this study was carried out in mice and the results may not be the same for people. Research in humans would be needed to understand fully the human biological processes involved and to establish whether MitoSNO is effective or safe when used in a similar way for real people. These experiments would need to include a rigorous assessment of the safety of the molecule. Despite the limitations, this intriguing research does highlight a potential biological target for further research. Ultimately, researchers hope to harness the protective effects of MitoSNO to reduce the damage in, and therefore aid the recovery of, people who have recently suffered heart failure due to lack of oxygen. Heart failure can have a significant adverse impact on quality of life so any treatment that can prevent or repair damage to the heart would be very valuable. Analysis by Bazian. Edited by NHS Choices. Follow Behind the Headlines on Twitter. Links To The Headlines Heart attack drug may reduce tissue damage. BBC News, May 27 201...
RHEUMATOID arthritis, and other forms of the disease, cause pain and discomfort among other symptoms. There is no cure, but can be treated using lifestyle changes, diet alterations and medication. Try using this neat trick to reduce pain caused by a flare-up.
It ’ s not always easy to tell if you have heart disease or have had a heart attack.
In one night, the Savage family lost two sons to opioid overdoses. Now they are working to prevent other families from experiencing the same pain.
Plunge into water at near-freezing temperatures, and your body goes into extreme distress. Your skin screams signals of pain. You can't breathe, because your chest is cramping up. Talking is nearly impossible. Your heart is pounding. Fear mounts -- as it should. Without any protection, you may lose consciousness in under 15 minutes. You'll be dead within an hour.
CONCLUSIONS: Elevation of TNFα level might be a predictor of OA progression after hip arthroscopy. PMID: 29665766 [PubMed - in process]
Conclusion: These results suggest that CPS technology accurately quantifies heart and respiration rates and measure fluid change- in the lungs. Significance: The CPS has the potential to accurately monitor lung fluid status noninvasively and continuously in a clinical and outpatient setting. Early and efficient management of lung fluid status is key in managing chronic conditions such heart failure, pulmonary hypertension, and acute respiration distress syndrome.
First bit of news: I’ve had absolutely no pain in my heel. It’s as good as new. I have to admit I’m still stunned…and I wonder if a more conventional doctor, let’s say a physiotherapist, would have made the connection between my relatively new eyeglass prescription and my heel pain. I doubt it. This makes me wonder how many similar cases there are, of people who think they have plantar fasciitis or tendonitis or, sorry for the mention! , heel spurs, but whose pain actually originated in a different part of the body, an easy-to-fix part of the body. Mind-blowing, eh? But the reason I&rsq...
CONCLUSION: In this consecutive real-world cohort of patients, the DCS was safe and efficacious when used for PPCI in patients with STEMI. PMID: 29666900 [PubMed - as supplied by publisher]
Objective. We evaluated the relationship between various risk scores (SYNTAX score (SS), SYNTAX score-II (SS-II), thrombolysis in myocardial infarction (TIMI) risk scores and Global Registry of Acute Coronary Events (GRACE) risk scores) and major adverse cardiovascular events (MACE) in non-ST-elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). Subjects and Methods: The study population were selected from among 589 patients who underwent coronary angiography with a diagnosis of NSTEMI. TIMI and GRACE risk scores were calculated. SS and SS-II were calculated in all patients,...
National Institutes of Health. 04/17/2018 This one-hour, 49-minute lecture describes the state of the opioid crisis, the state of the National Institutes of Health (NIH)'s efforts, and how clinicians, medical students, Ph.D. students, and other healthcare and research professionals can be a part of the solution. The focus of NIH's efforts center on ways to reduce the over-prescription of opioids, accelerate development of effective non-opioid therapies for pain, and provide more flexible options for treating opioid addiction. (Video or Multimedia)