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Molecule limits heart attack damage in mice

Conclusion This laboratory-based research in mice, which used a simulation designed to mimic the effects of a heart attack, appears to show that the molecule MitoSNO can prevent some of the heart tissue damage of a heart attack and the consequences of the return of blood to the heart (reperfusion). It is important to remember this was a small, early study in mice. Further studies in rodents would be needed to confirm these initial findings as true and accurate. Furthermore, this study was carried out in mice and the results may not be the same for people. Research in humans would be needed to understand fully the human biological processes involved and to establish whether MitoSNO is effective or safe when used in a similar way for real people. These experiments would need to include a rigorous assessment of the safety of the molecule. Despite the limitations, this intriguing research does highlight a potential biological target for further research. Ultimately, researchers hope to harness the protective effects of MitoSNO to reduce the damage in, and therefore aid the recovery of, people who have recently suffered heart failure due to lack of oxygen. Heart failure can have a significant adverse impact on quality of life so any treatment that can prevent or repair damage to the heart would be very valuable. Analysis by Bazian. Edited by NHS Choices. Follow Behind the Headlines on Twitter. Links To The Headlines Heart attack drug may reduce tissue damage. BBC News, May 27 201...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: NYT Health - Category: Consumer Health News Authors: Tags: Heart Tests (Medical) O'Donnell, Rosie Source Type: news
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Source: CNN.com - Health - Category: Consumer Health News Source Type: news
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Source: CNN.com - Health - Category: Consumer Health News Source Type: news
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Source: Journal of Orthopaedic Surgery - Category: Orthopaedics Authors: Tags: J Orthop Surg (Hong Kong) Source Type: research
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Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
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Source: Margaret's Corner - Category: Cancer & Oncology Authors: Tags: Blogroll celiac disease curcumin EBV Epstein-Barr virus inflammatory bowel disease lupus multiple sclerosis rheumatoid arthritis type 1 diabetes Source Type: blogs
CONCLUSION: In this consecutive real-world cohort of patients, the DCS was safe and efficacious when used for PPCI in patients with STEMI. PMID: 29666900 [PubMed - as supplied by publisher]
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Objective. We evaluated the relationship between various risk scores (SYNTAX score (SS), SYNTAX score-II (SS-II), thrombolysis in myocardial infarction (TIMI) risk scores and Global Registry of Acute Coronary Events (GRACE) risk scores) and major adverse cardiovascular events (MACE) in non-ST-elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). Subjects and Methods: The study population were selected from among 589 patients who underwent coronary angiography with a diagnosis of NSTEMI. TIMI and GRACE risk scores were calculated. SS and SS-II were calculated in all patients,...
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research
National Institutes of Health. 04/17/2018 This one-hour, 49-minute lecture describes the state of the opioid crisis, the state of the National Institutes of Health (NIH)'s efforts, and how clinicians, medical students, Ph.D. students, and other healthcare and research professionals can be a part of the solution. The focus of NIH's efforts center on ways to reduce the over-prescription of opioids, accelerate development of effective non-opioid therapies for pain, and provide more flexible options for treating opioid addiction. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news
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