Chemical constituents of Patrinia heterophylla Bunge and selective cytotoxicity against six human tumor cells

ConclusionsCompounds 1–10, 12 and 14–15 were isolated for the first time from the P. heterophylla. This result enriches the previous studies on the chemical constituents of P. heterophylla. Compounds 1 and 15 were reported for the first time have cytotoxic activities against tumor cells. Compounds 1, 5, 6, 7, 12, 15 showed cytotoxic activities against tumor cells. This result reveals that the active ingredient of P. heterophylla are composed of phenylpropanoids, iridoid and coumarin. This study provides some theoretical basis for the anti-tumor research of P. heterophylla.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research