HIV Did Not Stop Me From Having a Biological Child

On Monday, April 15, 2013, at 8:00 a.m., my life changed forever. My wife, Kasiah, and I welcomed our first child, a healthy girl named Finley Elizabeth Banks, into this world. She was perfect. But the journey to have a healthy, HIV-free biological child began many years before Finley’s birth. MoreFederal Appeals Court Strikes Down Utah's Gay Marriage Ban NBC NewsJessica N. Turner: Moms, Put on That Swimsuit Huffington PostShould the Cops Get to Look at Your Cellphone? NBC NewsParty's Over? GOP's Insurgents Take More Punches NBC NewsUruguay eliminates Italy; Did Suarez bite again? Sports IllustratedIn 1981, when I was two years old, I was diagnosed with Bilateral Wilms’ tumors, a cancer of the kidneys, which had also spread to both of my lungs. The prognosis was grim; treatment was aggressive. My tiny toddler body fought a battle that required 15 months of chemotherapy, radiation therapy, and surgeries that required multiple blood transfusions. Unknowingly, I was transfused with blood that infected me with HIV. Ten years later, having lived through a cancer-free childhood, doctors screened my blood during a routine oncology check-up. They discovered that I was HIV-positive. In 1991, the epidemic was still raging, and very little was known about how HIV/AIDS infected and affected children. Pediatric treatment options were limited — AZT (the drug that drives the plot of Dallas Buyers Club) had only been approved for young patients the previous year. Support fr...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized AIDS research Family & Parenting Fatherhood HIV medicine Science Source Type: news

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In this study, we further explored the mechanism underlying CD133-mediated cisplatin resistance in glioblastoma stem cells. We sorted human glioblastoma T98G and U87MG cells into CD133+ and CD133− pools and measured apoptosis and CD133 expression levels in response to cisplatin treatment. We predicted candidate microRNAs that might target CD133 and assessed their levels in cisplatin-treated CD133+ cells. Finally, we overexpressed miR-29a in CD133+ cells and tested its effects in cisplatin-mediated apoptosis and survival of CD133+ tumor bearing mice receiving cisplatin treatment. We found that CD133+ glioblastoma stem...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
In conclusion, molecular alterations in ependymoma involve miRNAs. In our report, we review the level of evidence for the biomarker candidacy of identified miRNAs. Confirmatory studies are necessary to establish robust biomarkers for the clinical management of ependymoma. Proteins regulated by differentially expressed miRNAs are additional candidate biomarkers and may offer targets for novel therapeutic interventions.
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
CONCLUSION: In conclusion, our study demonstrated that SCH-527123, a small-molecule antagonist for CXCR1 and CXCR2 inhibited cell proliferation, migration and invasion in melanoma via PI3K/AKT pathway. PMID: 30340844 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Authors: Snehalatha C, Priscilla S, Nanditha A, Arun R, Satheesh K, Ramachandran A Abstract Identification and treatment of individuals with prediabetes is crucial. Effective interventional strategies are key to reducing the diabetes risk at the population level. Lifestyle intervention is found to be more effective but more expensive. Evidence of potential benefits from pharmacotherapy is accumulating. The choice of a pharmacologic intervention to reduce the progression of type 2 diabetes (T2DM) in high risk individuals must consider the balance between the benefit to risk ratio. A meta-analysis of the results of t...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Padhiyar R, Chavan S, Dhampalwar S, Trivedi T, Moulick N Abstract Background: In India, it is estimated that up to 20,000 people die annually from snake bites. The present study was carried to out to estimate the snake bite related epidemiology, predictors of severity, relationship between type of snake, clinical severity, complications, outcome and usage pattern of polyvalent anti snake venom (ASV) in a tertiary care center. Methods: All indoor patients admitted in our institute with definitive history of bite by a snake, with or without presence of fang marks, Evidence of cellulitis, acute onset of...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Ankit BS, Agrawal R, Gadhwal A, Chahar C, Agrawal RP Abstract Objectives: Diabetes mellitus has been claimed to be a risk factor for the development of pancreatic carcinoma. CA 19-9 has a great sensitivity in detection of pancreatic adenocarcinoma. Metformin exhibits a strong and consistent antiproliferative action on several cancer cell lines including pancreatic cancer. We aim to determine the influence of metformin on CA 19-9 levels in type 2 diabetes mellitus patients. Methods: Total 193 patients with type 2 diabetes mellitus were registered for a single centre, cross-sectional study. On the basis ...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Basu A, Raj Y, Bhowmik P, Rahman M, Goswami RP Abstract A 22 year old male Indian patient presented with high grade fever, multiple joint pain, low back pain, generalized body ache since 6 months and erythematous pruritic rashes and atypical annular target like lesions over face, arm, leg and back and ulcers on hard palate and buccal mucosa for 2 months. Laboratory investigations showed a speckled pattern anti-nuclear antibody with a titer>1:160 and positive SS-A, dsDNA auto-antibodies and Rheumatoid factor. Diagnosis of Rowell's syndrome was made based on clinical and laboratory finding and the patient...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: Diagnosis of CNS TB should be based on clinical features and 3 or more supportive criteria rather than CSF positivity on staining or culture. Rapid and early diagnosis by positive CSF PCR and CT/MRI findings should replace CSF AFB staining and culture in further for the diagnosis of CNS TB. PMID: 30341844 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
CANCER symptoms vary depending on which part of the body is affected by a tumour. You could be at risk of the deadly condition if you have this painful sign.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In conclusion, we have focused on the role of B[a]P contamination in food for cancer risk and the possible molecular mechanism of cancer development, which could provide a way to reduce cancer incidence either by regulatory efforts or modifying food processed technology.
Source: Current Opinion in Food Science - Category: Food Science Source Type: research
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