Lasers used to regenerate damaged teeth

Conclusion This laboratory study has shown that low-power laser therapy can direct dental stem cells to grow into one type of dental tissue, dentin. A strength of the study is that it used the dental pulp from molar teeth in rats, which are similar to humans, rather than their incisors, which are open-rooted and continue to grow for life to replace loss from gnawing.  Limitations highlighted by the authors include: the small sample size as a result of the limited availability of these particular rodents technical difficulties of growing minute rodent teeth widespread growth of dental tissue, which the authors think is because of the large area that was exposed to laser – they are hopeful that this can be improved with better technique and in larger animals and humans Other factors that will need to be taken into account are that although the authors wanted to create a way to stimulate the cells without the toxic effects of chemicals or transplant, there is still the potential for side effects from the laser therapy. It is not yet known if the laser therapy stimulates other unwanted cell production or whether it might damage other cells. Further research is required before this technique could progress to human trials, but it is a promising start. There is also the possibility that laser therapy could be used to stimulate the production of other specialised cells. Even if the research progresses well, it would probably be at least a decade bef...
Source: NHS News Feed - Category: Consumer Health News Tags: Medical practice Genetics/stem cells Source Type: news

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Authors: Campello E, Spiezia L, Adamo A, Simioni P Abstract INTRODUCTION: Fifty-three years after the first description of an inherited prothrombotic condition (antithrombin deficiency), our knowledge on hereditary and acquired causes of hypercoagulability that can predispose carriers to venous thromboembolism (VTE) has greatly improved. Areas covered: Main causes of hereditary thrombophilia are summarized alongside new prothrombotic mutations recently discovered. The main causes of acquired thrombophilia, and namely, antiphospholipid antibody syndrome and hyperhomocysteinemia, are also discussed together with othe...
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
This article summarizes the epithelial and subepithelial dystrophies of the cornea, which, according to IC3D are the following: · epithelial basement membrane dystrophy (EBMD),. · epithelial recurrent erosion dystrophy (ERED),. · subepithelial mucinous corneal dystrophy (SMCD),. · Meesmann corneal dystrophy (MECD),. · Lisch epithelial corneal dystrophy (LECD),. · gelatinous drop-like corneal dystrophy (GDLD).. The main problem concerning almost all dystrophies of the corneal epithelium are epithelial defects (erosion) associated with pain, epiphora and red eyes. In addition, all dy...
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
Abstract Anterior gradient protein 2 homolog (AGR) is a potential tumor biomarker and plays an important role in tissue development and regeneration. The intracellular detection of AGR is rarely reported. By conjugating the AGR aptamer with a cytosine base sequence as Ag cluster template, a highly fluorescent probe (MA@AgNCs) was synthesized for targeting intracellular AGR. The MA@AgNCs display a maximum fluorescence peak at 565 nm, and possess an excellent quantum yield (QY = 87.43%), small size, great biocompatibility, low toxicity, and good stability. Moreover, the as synthesized MA@AgNCs show high specific...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
In this study, a novel approach for preparing fluorescent boronic-acid-modified carbon dots (C-dots) for the detection of SA was developed. The functionalized C-dots were synthesized by a facile, one-step hydrothermal method using 3-pyridineboronic acid as the sole carbon source. The added SA selectively recognized the C-dots, leading to the fluorescence quenching of the C-dots in a linear range of 80-4000 μM with a detection limit of 54 μM. The as-developed boronic-acid nanoprobe was successfully applied for the detection of SA in human serum samples with satisfactory results. In addition, this method afforded r...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: Oral health promotion and disease prevention is an emergent need for older adult populations residing in urban and rural communities of the state of Texas. Analysis revealed that the majority of the older adult populations in both settings to have financial and socioeconomic barriers to access preventative and restorative dental care services. PMID: 29118278 [PubMed - in process]
Source: Journal of Dental Hygiene - Category: Dentistry Tags: J Dent Hyg Source Type: research
The objective of this project was to integrate preventive oral care into pediatric oncology care. 
. METHODS: This project consisted of an educational program for pediatric oncology providers who completed pre- and postprogram surveys assessing oral health knowledge, attitudes, and practice; attended an oral health education session; and performed oral assessment and fluoride varnish application on children during cancer treatment. 
. FINDINGS: Three major outcomes resulted from this project. PMID: 28945720 [PubMed - in process]
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research
Poor oral health afflicts many low-income and other vulnerable populations. Poor oral health can lead to unnecessary tooth decay, periodontal disease, plaque buildup, pain, and even the quiet and deadly advancement of oral cancer. It also leads to unnecessary and expensive visits to the emergency department to treat pain of tooth decay and periodontal disease but not the causal conditions. Finding ways to improve oral health in low-income communities is essential to good health and helping individuals move from poverty to middle class status.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Feature Article Source Type: research
A dentist is simply a doctor in charge of your oral hygiene. So, let me ask you a question: How many times have you visited a dentist this year? Alright, you don't have to tell me your answer. Most people don't visit a dentist until they have severe problems in their oral area. I am also part of this group even if I don't want to admit it. This is because most people are unaware of the importance and usefulness of a dentist. It is recommended that you visit a dentist at least twice in a year to keep your gums and teeth healthy. Dental visits are supposed to start at the age of 8 years when the permanent teeth are repl...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This article highlights 2 cases illustrating how interprofessional team dynamics can affect patient outcomes.
Source: Dental Clinics of North America - Category: Dentistry Authors: Source Type: research
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