Lasers used to regenerate damaged teeth

Conclusion This laboratory study has shown that low-power laser therapy can direct dental stem cells to grow into one type of dental tissue, dentin. A strength of the study is that it used the dental pulp from molar teeth in rats, which are similar to humans, rather than their incisors, which are open-rooted and continue to grow for life to replace loss from gnawing.  Limitations highlighted by the authors include: the small sample size as a result of the limited availability of these particular rodents technical difficulties of growing minute rodent teeth widespread growth of dental tissue, which the authors think is because of the large area that was exposed to laser – they are hopeful that this can be improved with better technique and in larger animals and humans Other factors that will need to be taken into account are that although the authors wanted to create a way to stimulate the cells without the toxic effects of chemicals or transplant, there is still the potential for side effects from the laser therapy. It is not yet known if the laser therapy stimulates other unwanted cell production or whether it might damage other cells. Further research is required before this technique could progress to human trials, but it is a promising start. There is also the possibility that laser therapy could be used to stimulate the production of other specialised cells. Even if the research progresses well, it would probably be at least a decade bef...
Source: NHS News Feed - Category: Consumer Health News Tags: Medical practice Genetics/stem cells Source Type: news

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Medtronic seems to be on a roll when it comes to innovation. The Dublin-based company has received the greenlight from FDA for an expanded indication of the Kyphon HV-R Bone Cement. Under the new indication, Medtronic can market Kyphon for the fixation of pathological fractures of the sacral vertebral body using sacral vertebroplasty or sacroplasty. Sacral insufficiency fractures (SIFs) are a common cause of debilitating back pain. SIFs mimic the symptoms of lumbar spine pathology. Studies show more than two-thirds of patients diagnosed with SIFs aren't able to associate their pain with a traumatic event. As a result, phys...
Source: MDDI - Category: Medical Devices Authors: Tags: Orthopedics Source Type: news
Service on demand (repair) is a regular part of medical equipment maintenance. Repair can be approached as a 1-time situation of finding the problem and fixing it, or it can be approached as an integral part of keeping the medical device environment in full functioning condition at managed cost. The latter requires an organized commitment to not only repair but also determine why repair was needed and what if anything could be done to reduce subsequent failures. This is particularly the case for repeat service calls over an unexpectedly short period.
Source: Journal of Clinical Engineering - Category: Medical Devices Tags: Feature Articles Source Type: research
In addition to being an aerosolized topical local anesthetic, Cetacaine Spray has the physical property of being an excellent medical lubricant for airway management and related procedures. This is a result of the constituent ingredient dipropylene glycol (DPG). However, because of the presence of benzocaine, this medication can cause methemoglobinemia if absorbed excessively. The authors speculate that aerosolized DPG may be useful as medical lubricant, independent of the local anesthetics contained within Cetacaine Spray. Further research into this potential application of DPG may be indicated.
Source: Journal of Clinical Engineering - Category: Medical Devices Tags: Feature Articles Source Type: research
Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer, Published online: 21 June 2018; doi:10.1038/s41397-018-0030-8Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer
Source: The Pharmacogenomics Journal - Category: Drugs & Pharmacology Authors: Source Type: research
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: Oral health promotion and disease prevention is an emergent need for older adult populations residing in urban and rural communities of the state of Texas. Analysis revealed that the majority of the older adult populations in both settings to have financial and socioeconomic barriers to access preventative and restorative dental care services. PMID: 29118278 [PubMed - in process]
Source: Journal of Dental Hygiene - Category: Dentistry Tags: J Dent Hyg Source Type: research
The objective of this project was to integrate preventive oral care into pediatric oncology care. 
. METHODS: This project consisted of an educational program for pediatric oncology providers who completed pre- and postprogram surveys assessing oral health knowledge, attitudes, and practice; attended an oral health education session; and performed oral assessment and fluoride varnish application on children during cancer treatment. 
. FINDINGS: Three major outcomes resulted from this project. PMID: 28945720 [PubMed - in process]
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research
Poor oral health afflicts many low-income and other vulnerable populations. Poor oral health can lead to unnecessary tooth decay, periodontal disease, plaque buildup, pain, and even the quiet and deadly advancement of oral cancer. It also leads to unnecessary and expensive visits to the emergency department to treat pain of tooth decay and periodontal disease but not the causal conditions. Finding ways to improve oral health in low-income communities is essential to good health and helping individuals move from poverty to middle class status.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Feature Article Source Type: research
A dentist is simply a doctor in charge of your oral hygiene. So, let me ask you a question: How many times have you visited a dentist this year? Alright, you don't have to tell me your answer. Most people don't visit a dentist until they have severe problems in their oral area. I am also part of this group even if I don't want to admit it. This is because most people are unaware of the importance and usefulness of a dentist. It is recommended that you visit a dentist at least twice in a year to keep your gums and teeth healthy. Dental visits are supposed to start at the age of 8 years when the permanent teeth are repl...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This article highlights 2 cases illustrating how interprofessional team dynamics can affect patient outcomes.
Source: Dental Clinics of North America - Category: Dentistry Authors: Source Type: research
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